Is Duchenne Gene Therapy a Suitable Treatment Despite its Immunogenic Class Effect?
Progressive muscle weakness and eventual mortality as a result of cardiomyopathy or respiratory complications are the hallmarks of Duchenne muscular dystrophy (DMD), a severe...
New Research on Duchenne Muscular Dystrophy Protein Interactions Lead to More Targeted Therapies
A pioneering discovery has shown the complicated relationships between dystrophin, a muscle stability protein, and its companion protein, dystrobrevin, opening new avenues for studying...
Zebrafish Modeling Shows Promise in Duchenne (DMD) Research
Zebrafish (Danio rerio) has emerged as a valuable model organism for investigating musculoskeletal development and the pathophysiology of associated diseases. Key genes and biological...
SPLICER Gene Editing Tool Holds A Lot of Potential to Treat Duchenne Muscular Dystrophy
A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of...
Researchers Discover 18-Digit Code (Wnt7a) that Allows Proteins to Hitch a Ride Around the Body
Researchers from the University of Ottawa and The Ottawa Hospital have found an 18-digit code (Wnt7a) that proteins can use to bind to exosomes,...