Wellcome Trust Donates £10 Million to Treat Rare Diseases

The Wellcome Trust, the biggest medical foundation in the world, has committed a £10 million initial investment to accelerate the discovery of rare disease therapies, announced that by accelerating treatments for numerous terminal diseases, it might do more benefit than damage.

The new Synthetic Human Genome Project (SynHG) is receiving £10 million from Wellcome Trust to build the fundamental instruments, technologies, and techniques that will eventually allow scientists to synthesize genomes. The Synthetic Human Genome Project (SynHG) could enable studies of Duchenne Muscular Dystrophy to progress more quickly and produce full-length dystrophin. – Read More: SynHG

Synthetic Human Genome Project

Researchers have been looking into the idea of writing genomes since the Human Genome Project was completed in 2003. Scientists are now working on the technologies that will enable it.

It will likely take decades to create a complete synthetic human genome. The SynHG project will develop the fundamental tools to make this work possible over the course of the next five years.

Although this presents a significant obstacle, there are significant potential advantages. Our knowledge of health and illness would be profoundly altered by a fully synthetic human genome and the research required to produce it.

It might eventually result in novel medical interventions, such as tissue transplantation that is resistant to viruses and designer cell-based medicines. By designing plant species to endure climate extremes, for example, it may also aid in the defense of biodiversity and food security.

What is Genome Synthesis?

Genome synthesis, as opposed to genome editing, enables larger-scale modifications and the identification of causal links between human traits and DNA.

According to Michael Dunn, Director of Discovery Research at Wellcome Trust, “our DNA determines who we are and how our bodies work.” “The SynHG project is at the forefront of one of the most exciting areas of scientific research thanks to recent technological advances.”

“We will transform our understanding of life and wellbeing by developing the tools and techniques required to synthesize a human genome, which will answer questions about our health and disease that we cannot even predict yet.”

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