{"id":8848,"date":"2026-10-05T19:00:36","date_gmt":"2026-10-05T16:00:36","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=8848"},"modified":"2026-10-05T19:09:42","modified_gmt":"2026-10-05T16:09:42","slug":"deramiocel-hope-3-24-month-results-duchenne","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/deramiocel-hope-3-24-month-results-duchenne\/","title":{"rendered":"Deramiocel \u5728\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u60a3\u8005\u4e2d\u663e\u793a\u51fa\u79ef\u6781\u7684 24 \u4e2a\u6708 HOPE-3 \u7814\u7a76\u7ed3\u679c\u3002"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>Capricor Therapeutics \u62a5\u544a\u4e86 HOPE-3 \u7814\u7a76\u7684\u65b0\u7ed3\u679c\uff0c\u8be5\u7814\u7a76\u8bc4\u4f30\u4e86 Deramiocel \u5bf9\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD) \u60a3\u8005\u7684\u7597\u6548\u3002.<\/strong> \u4e3a\u671f 24 \u4e2a\u6708\u7684\u5f00\u653e\u6807\u7b7e\u6269\u5c55\u6570\u636e\u91cd\u70b9\u5173\u6ce8\u4e0a\u80a2\u529f\u80fd\uff0c\u7ed3\u679c\u663e\u793a\uff0c\u5728\u63a5\u53d7\u5b89\u6170\u5242\u6cbb\u7597\u4e00\u5e74\u540e\u5f00\u59cb\u63a5\u53d7 Deramiocel \u6cbb\u7597\u7684\u60a3\u8005\uff0c\u5728\u6cbb\u7597\u7684\u7b2c\u4e00\u5e74\u4e2d\uff0c\u4e0a\u80a2\u529f\u80fd\u4e0b\u964d\u7684\u901f\u5ea6\u660e\u663e\u8f83\u6162\u3002.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6700\u65b0\u7814\u7a76\u7ed3\u679c\u5df2\u57282026\u5e74\u4e16\u754c\u808c\u8089\u5b66\u4f1a\u5927\u4f1a\u4e0a\u516c\u5e03\u3002HOPE-3\u7814\u7a76\u662f\u4e00\u9879\u8bc4\u4f30Deramiocel\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u60a3\u8005\u76843\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002\u8be5\u7814\u7a76\u6700\u521d\u7eb3\u5165\u4e86106\u540d\u60a3\u8005\uff0c\u91c7\u7528\u968f\u673a\u3001\u5b89\u6170\u5242\u5bf9\u7167\u8bbe\u8ba1\u3002\u5b8c\u6210\u8be5\u9636\u6bb5\u7684\u60a3\u8005\u53ef\u7ee7\u7eed\u63a5\u53d7Deramiocel\u6cbb\u7597\uff0c\u8be5\u9636\u6bb5\u4e3a\u5f00\u653e\u6807\u7b7e\u6269\u5c55\u7814\u7a76\u3002\u4e86\u89e3\u66f4\u591a\uff1a <a href=\"https:\/\/dmdwarrior.com\/zh\/what-is-deramiocel\/\" target=\"_blank\" rel=\"noreferrer noopener\">Deramiocel \u662f\u4ec0\u4e48\uff1f<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u5f00\u59cb\u4f7f\u7528Deramiocel\u540e\uff0c\u4e0a\u80a2\u529f\u80fd\u4e0b\u964d\u901f\u5ea6\u51cf\u7f13\u3002<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u6700\u91cd\u8981\u7684\u53d1\u73b0\u4e4b\u4e00\u6765\u81ea\u7b2c\u4e00\u5e74\u63a5\u53d7\u5b89\u6170\u5242\u6cbb\u7597\uff0c\u7136\u540e\u8f6c\u800c\u63a5\u53d7 Deramiocel \u6cbb\u7597\u7684\u60a3\u8005\u3002.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5728\u670d\u7528\u5b89\u6170\u5242\u7684\u7b2c\u4e00\u5e74\uff0c\u8fd9\u4e9b\u60a3\u8005\u7684 PUL 2.0 \u603b\u5206\u5e73\u5747\u4e0b\u964d\u4e86 2.05 \u5206\u3002.<\/strong> \u5728\u968f\u540e\u7684\u4e00\u5e74\u91cc\uff0cDeramiocel \u5f00\u59cb\u8fd0\u884c\u540e\uff0c\u5176\u5e73\u5747\u8dcc\u5e45\u653e\u7f13\u81f3 0.49 \u70b9\u3002.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u6839\u636e Capricor \u7684\u6570\u636e\uff0c\u4e0e\u60a3\u8005\u524d\u4e00\u5e74\u670d\u7528\u5b89\u6170\u5242\u76f8\u6bd4\uff0c\u8fd9\u4ee3\u8868\u4e0a\u80a2\u8870\u9000\u901f\u5ea6\u964d\u4f4e\u4e86 76%\u3002.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e0a\u80a2\u529f\u80fd\u5bf9\u4e8e\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u60a3\u8005\u6765\u8bf4\u5c24\u4e3a\u91cd\u8981\uff0c\u56e0\u4e3a\u5b83\u4e0e\u72ec\u7acb\u751f\u6d3b\u548c\u65e5\u5e38\u6d3b\u52a8\u5bc6\u5207\u76f8\u5173\u3002.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u4ece\u4e00\u5f00\u59cb\u5c31\u63a5\u53d7 Deramiocel \u6cbb\u7597\u7684\u60a3\u8005<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u8be5\u7814\u7a76\u8fd8\u5bf9\u4ece\u8bd5\u9a8c\u5f00\u59cb\u5c31\u63a5\u53d7 Deramiocel \u6cbb\u7597\u7684\u60a3\u8005\u8fdb\u884c\u4e86\u8ddf\u8e2a\u3002.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5728\u8be5\u7ec4\u4e2d\uff0c\u5e73\u5747 PUL 2.0 \u5206\u6570\u5728\u7b2c\u4e00\u5e74\u4e0b\u964d\u4e86 0.95 \u5206\uff0c\u5728\u7b2c\u4e8c\u5e74\u4e0b\u964d\u4e86 0.89 \u5206\u3002.<\/strong> \u4e24\u5e74\u95f4\u76f8\u4f3c\u7684\u7ed3\u679c\u8868\u660e\uff0c\u6cbb\u7597\u7b2c\u4e8c\u5e74\u75c5\u60c5\u4e0b\u964d\u901f\u5ea6\u4ecd\u5728\u51cf\u7f13\u3002.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e0e\u81ea\u7136\u53f2\u7684\u6bd4\u8f83<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">24 \u4e2a\u6708\u65f6\uff0c\u4e24\u7ec4\u53d7\u8bd5\u8005\u7684\u4e0a\u80a2\u529f\u80fd\u4e0b\u964d\u7a0b\u5ea6\u5747\u5c0f\u4e8e\u81ea\u7136\u53f2\u6a21\u578b\u9884\u6d4b\u503c\u3002.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7b2c\u4e00\u5e74\u63a5\u53d7\u5b89\u6170\u5242\u6cbb\u7597\uff0c\u7b2c\u4e8c\u5e74\u63a5\u53d7 Deramiocel \u6cbb\u7597\u7684\u60a3\u8005\u89c2\u5bdf\u5230\u7684\u53d8\u5316\u4e3a -3.76 \u5206\uff0c\u800c\u9884\u6d4b\u7684\u81ea\u7136\u75c5\u7a0b\u4e0b\u964d\u4e3a -5.35 \u5206\u3002.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u63a5\u53d7 Deramiocel \u6cbb\u7597\u4e24\u5e74\u7684\u60a3\u8005\u89c2\u5bdf\u5230\u7684\u53d8\u5316\u4e3a -3.42 \u5206\uff0c\u800c\u9884\u6d4b\u7684\u4e0b\u964d\u503c\u4e3a -5.88 \u5206\u3002.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7136\u800c\uff0cCapricor \u6307\u51fa\uff0c\u8fd9\u4e9b\u81ea\u7136\u53f2\u6bd4\u8f83\u53ea\u662f\u63cf\u8ff0\u6027\u7684\uff0c\u5e76\u975e\u57fa\u4e8e\u60a3\u8005\u5339\u914d\u6216\u7edf\u8ba1\u68c0\u9a8c\u3002.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u8fd9\u4e9b\u7ed3\u679c\u610f\u5473\u7740\u4ec0\u4e48<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3a\u671f24\u4e2a\u6708\u7684\u7ed3\u679c\u8fdb\u4e00\u6b65\u8bc1\u5b9e\uff0cDeramiocel\u53ef\u80fd\u5ef6\u7f13\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u60a3\u8005\u4e0a\u80a2\u529f\u80fd\u7684\u4e27\u5931\u3002\u6700\u663e\u8457\u7684\u53d1\u73b0\u662f\uff0c\u4ece\u5b89\u6170\u5242\u7ec4\u8f6c\u4e3aDeramiocel\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u5176\u529f\u80fd\u8870\u9000\u901f\u5ea6\u663e\u8457\u964d\u4f4e\u3002.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u540c\u65f6\uff0c\u8be5\u5f00\u653e\u6807\u7b7e\u6269\u5c55\u7814\u7a76\u7684\u8bbe\u8ba1\u548c\u6837\u672c\u91cf\u5747\u4e0d\u8db3\u4ee5\u8fdb\u884c24\u4e2a\u6708\u65f6\u7684\u6b63\u5f0f\u7edf\u8ba1\u6bd4\u8f83\u3002\u56e0\u6b64\uff0c\u5e94\u5728\u7814\u7a76\u8bbe\u8ba1\u7684\u5c40\u9650\u6027\u8303\u56f4\u5185\u89e3\u8bfb\u7814\u7a76\u7ed3\u679c\u3002.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Capricor \u5df2\u5c06\u8fd9\u4e9b\u6570\u636e\u4f5c\u4e3a\u5176 Deramiocel \u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7 (BLA) \u7684\u91cd\u5927\u4fee\u8ba2\u7684\u4e00\u90e8\u5206\u63d0\u4ea4\u3002. <strong>FDA \u76ee\u524d\u7684 PDUFA \u76ee\u6807\u5ba1\u6279\u65e5\u671f\u4e3a 2026 \u5e74 11 \u6708 22 \u65e5\u3002.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e86\u89e3\u66f4\u591a<\/strong>:\u00a0<a href=\"https:\/\/dmdwarrior.com\/clinical-trials\/map\/\" target=\"_blank\" rel=\"noopener\">\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u4e34\u5e8a\u8bd5\u9a8c\u5730\u70b9\u5730\u56fe<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Capricor Therapeutics has reported new results from the HOPE-3 study evaluating Deramiocel in people with Duchenne muscular dystrophy (DMD). The 24-month open-label extension data focused on Upper Limb Function and showed that patients who started Deramiocel after one year on placebo experienced a significantly slower rate of upper limb decline during their first year of [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":8849,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[90,86,87,85,88,926,923],"class_list":["post-8848","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-cap-1002","tag-capricor","tag-capricor-therapeutics","tag-deramiocel","tag-fda","tag-hope-3","tag-wms-2026"],"subtitle":"Capricor Therapeutics \u62a5\u544a\u4e86 Deramiocel \u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u4ee4\u4eba\u9f13\u821e\u7684 24 \u4e2a\u6708 HOPE-3 \u7814\u7a76\u7ed3\u679c\u3002\u6570\u636e\u663e\u793a\uff0c\u60a3\u8005\u4ece\u5b89\u6170\u5242\u7ec4\u8f6c\u4e3a\u6cbb\u7597\u7ec4\u540e\uff0c\u4e0a\u80a2\u529f\u80fd\u4e0b\u964d\u901f\u5ea6\u51cf\u7f13\uff0c\u5305\u62ec 76% \u7684\u51cf\u5c11\u3002.","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/8848","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=8848"}],"version-history":[{"count":2,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/8848\/revisions"}],"predecessor-version":[{"id":8851,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/8848\/revisions\/8851"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/8849"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=8848"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=8848"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=8848"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}