SRP-9001-104 \u5728\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD) \u4e2d\u7684\u5e94\u7528\uff1a\u8bd5\u9a8c\u62a5\u544a\u4e86\u4e09\u540d\u5728\u63a5\u53d7 Sarepta \u7684 ELEVIDYS \u6cbb\u7597\u524d\u63a5\u53d7 imlifidase \u6cbb\u7597\u7684 DMD \u60a3\u8005\u7684\u521d\u6b65\u7ed3\u679c\u3002.<\/p>\n\n\n\n
\u4e24\u9879\u57fa\u56e0\u6cbb\u7597\u8bd5\u9a8c\uff0c\u4e00\u9879\u7531 Sarepta \u8d5e\u52a9\uff0c\u53e6\u4e00\u9879\u7531 Genethon \u8d5e\u52a9\uff0c\u5747\u652f\u6301\u4f0a\u7c73\u5229\u9176\u80fd\u591f\u5927\u5e45\u51cf\u5c11\u6297 AAV \u6297\u4f53\uff0c\u4ece\u800c\u5141\u8bb8\u8fdb\u884c\u57fa\u56e0\u6cbb\u7597\u3002.<\/p>\n\n\n\n
\u5355\u6b21\u6ce8\u5c04\u4f0a\u7c73\u5229\u9176\u540e\uff0c\u60a3\u8005\u7684IgG\u6297\u4f53\u6c34\u5e73\u8fc5\u901f\u4e0b\u964d\uff0c\u964d\u81f3\u4f4e\u4e8e\u57fa\u7ebf\u6c34\u5e73\u226595%\u3002\u6b64\u5916\uff0c\u9884\u5148\u5b58\u5728\u7684\u6297AAV\u6297\u4f53\u6ef4\u5ea6\u4e5f\u964d\u81f31:400\u4ee5\u4e0b\uff0c\u4ece\u800c\u4f7f\u60a3\u8005\u80fd\u591f\u63a5\u53d7ELEVIDYS\u6cbb\u7597\u3002\u8bd5\u9a8c\u4e2d\u672a\u89c2\u5bdf\u5230\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u53f7\u3002\u8fd9\u4e9b\u521d\u6b65\u4e34\u5e8a\u6570\u636e\u652f\u6301\u4f0a\u7c73\u5229\u9176\u80fd\u591f\u663e\u8457\u964d\u4f4e\u6297AAV\u6297\u4f53\u6c34\u5e73\uff0c\u4ece\u800c\u4f7f\u57fa\u56e0\u6cbb\u7597\u5f97\u4ee5\u8fdb\u884c\u3002. \u9605\u8bfb\u66f4\u591a\u5173\u4e8e\u4f0a\u59c6\u5229\u83f2\u9176\u7684\u4fe1\u606f<\/a>.<\/p>","protected":false},"excerpt":{"rendered":" SRP-9001-104 in Duchenne muscular dystrophy (DMD): Topline results were reported for three patients with DMD treated with imlifidase prior to administration of Sarepta’s ELEVIDYS in the trial. Two gene therapy trials, one sponsored by Sarepta and the other sponsored by Genethon, support the ability of imlifidase to substantially reduce anti-AAV antibodies to allow administration of […]<\/p>\n","protected":false},"author":1,"featured_media":4954,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[368,448,61,401],"class_list":["post-4953","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-aav-based-gene-therapy","tag-anti-aav","tag-gene-therapy","tag-hansa-biopharma"],"subtitle":"\u521d\u6b65\u4e34\u5e8a\u6570\u636e\u652f\u6301\u4f0a\u7c73\u5229\u9176\u80fd\u591f\u5927\u5e45\u964d\u4f4e\u6297AAV\u6297\u4f53\uff0c\u4ece\u800c\u5141\u8bb8\u8fdb\u884c\u57fa\u56e0\u6cbb\u7597\u3002.","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/4953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=4953"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/4953\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/4954"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=4953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=4953"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=4953"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}