{"id":4743,"date":"2025-10-07T15:37:43","date_gmt":"2025-10-07T12:37:43","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=4743"},"modified":"2025-11-03T20:18:29","modified_gmt":"2025-11-03T17:18:29","slug":"sonothera-presents-new-data-at-esgct-2025-demonstrating-expression-of-full-length-human-dystrophin-using-targeted-ultrasound-mediated-delivery-to-treat-duchenne-muscular-dystrophy","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/sonothera-presents-new-data-at-esgct-2025-demonstrating-expression-of-full-length-human-dystrophin-using-targeted-ultrasound-mediated-delivery-to-treat-duchenne-muscular-dystrophy\/","title":{"rendered":"SonoThera \u5728 ESGCT 2025 \u4e0a\u5c55\u793a\u65b0\u6570\u636e\uff0c\u8bc1\u660e\u5229\u7528\u9776\u5411\u8d85\u58f0\u4ecb\u5bfc\u9012\u9001\u5168\u957f\u4eba\u7c7b\u808c\u8425\u517b\u4e0d\u826f\u86cb\u767d\u6765\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7"},"content":{"rendered":"<p class=\"wp-block-paragraph\">SonoThera \u662f\u4e00\u5bb6\u81f4\u529b\u4e8e\u901a\u8fc7\u5f00\u53d1\u4e0b\u4e00\u4ee3\u57fa\u56e0\u836f\u7269\u6765\u6cbb\u7597\u4eba\u7c7b\u75be\u75c5\u6839\u6e90\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u8be5\u516c\u53f8\u4eca\u5929\u5ba3\u5e03\uff0c\u5c06\u5728 10 \u6708 7 \u65e5\u81f3 10 \u65e5\u5728\u897f\u73ed\u7259\u585e\u7ef4\u5229\u4e9a\u4e3e\u884c\u7684\u7b2c 32 \u5c4a\u6b27\u6d32\u57fa\u56e0\u548c\u7ec6\u80de\u6cbb\u7597\u5b66\u4f1a\u5927\u4f1a\u4e0a\u5c55\u793a\u65b0\u6570\u636e\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6d77\u62a5\u5c55\u793a\u7684\u91cd\u70b9\u662f\u4f7f\u7528 SonoThera \u4e13\u6709\u7684 RIPPLETM \u8d85\u58f0\u4ecb\u5bfc\u9012\u9001 (UMD) \u6280\u672f\u5c06\u5168\u957f\u4eba\u7c7b\u808c\u8425\u517b\u4e0d\u826f\u86cb\u767d\u6709\u6548\u8f7d\u8377\u9012\u9001\u81f3\u9aa8\u9abc\u808c\u3001\u5fc3\u810f\u548c\u6a2a\u8188\u819c\u808c\u8089\uff0c\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD)\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u8d85\u97f3\u6ce2\u4ecb\u5c0e\u7684\u50b3\u8f38<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u65b0\u6570\u636e\u8868\u660e\uff0cRIPPLETM \u80fd\u591f\u5b9e\u73b0\u591a\u79cd\u6709\u6548\u8f7d\u8377\u5f62\u5f0f\u7684\u5e7f\u6cdb\u3001\u9ad8\u5ea6\u9488\u5bf9\u6027\u7684\u751f\u7269\u5206\u5e03\uff0c\u800c\u4e0d\u53d7\u5c3a\u5bf8\u9650\u5236\uff0c\u4ece\u800c\u5b9e\u73b0\u53ef\u91cd\u590d\u7ed9\u836f\u7684\u57fa\u56e0\u836f\u7269\uff0c\u5e76\u4e14\u5b89\u5168\u3001\u8010\u53d7\u6027\u826f\u597d\u4e14\u5177\u6709\u6210\u672c\u6548\u76ca\u3002\u2013 <a href=\"https:\/\/dmdwarrior.com\/zh\/sonothera-ultrasound-mediated-delivery-method-can-deliver-full-length-dystrophin-to-cells\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u4ec0\u4e48\u662f\u8d85\u58f0\u6ce2\u4ecb\u5bfc\u7684\u9012\u9001\u65b9\u6cd5\uff1f<\/a> \u2013<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u5168\u957f\u4eba\u7c7b\u808c\u8425\u517b\u4e0d\u826f\u86cb\u767d<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u65b0\u6570\u636e\u8bc1\u660e\u4e86 UMD \u6280\u672f\u8f93\u9001\u57fa\u56e0\u836f\u7269\u7684\u80fd\u529b\uff0c\u5141\u8bb8\u5728\u5c0f\u9f20\u548c\u975e\u4eba\u7c7b\u7075\u957f\u7c7b\u52a8\u7269 (NHP) \u6a21\u578b\u7684\u9aa8\u9abc\u3001\u5fc3\u810f\u548c\u8188\u808c\u7ec4\u7ec7\u4e2d\u8868\u8fbe\u5168\u957f\u4eba\u7c7b\u808c\u8425\u517b\u4e0d\u826f\u86cb\u767d\u3002<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u7ed3\u679c\u8868\u660e\uff0c\u5728 NHP \u4e2d\u5df2\u7ecf\u5b9e\u73b0\u4e86\u9ad8\u6c34\u5e73\u7684\u6301\u4e45\u4eba\u7c7b\u808c\u8425\u517b\u4e0d\u826f\u86cb\u767d\u8868\u8fbe\uff0c\u8d85\u8fc7\u4e86\u5185\u6e90\u6027\u6c34\u5e73\u7684 50%\u3002<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6d77\u62a5\u5c55\u793a\u91cd\u70b9\u4ecb\u7ecd\u4e86 SonoThera \u4f7f\u7528\u8d85\u58f0\u4ecb\u5bfc\u9012\u9001 (UMD) \u7684\u4e13\u6709\u3001\u975e\u75c5\u6bd2\u3001\u975e\u4fb5\u5165\u6027\u65b9\u6cd5\u3002<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">SonoThera \u9996\u5e2d\u6267\u884c\u5b98 Kenneth Greenberg \u535a\u58eb\u8868\u793a\uff1a\u201c\u6211\u4eec\u7684\u65b0\u6570\u636e\u8fdb\u4e00\u6b65\u8bc1\u660e\u4e86\u8d85\u58f0\u4ecb\u5bfc\u57fa\u56e0\u836f\u7269\u9012\u9001\u7684\u6f5c\u529b\u53ca\u5176\u5728\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7b49\u590d\u6742\u75be\u75c5\u65b9\u9762\u7684\u72ec\u7279\u80fd\u529b\u3002\u5c24\u5176\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u6211\u4eec\u80fd\u591f\u4ee5\u6301\u4e45\u3001\u5b89\u5168\u3001\u53ef\u91cd\u590d\u7ed9\u836f\u4e14\u65e0\u521b\u7684\u65b9\u5f0f\u5c06\u9776\u5411\u7684\u5168\u957f\u4eba\u7c7b\u808c\u8425\u517b\u4e0d\u826f\u86cb\u767d\u9012\u9001\u81f3\u9aa8\u9abc\u808c\u3001\u5fc3\u810f\u808c\u548c\u8188\u808c\uff0c\u8fd9\u5c55\u73b0\u4e86 UMD \u5982\u4f55\u514b\u670d\u5f53\u524d\u57fa\u56e0\u6cbb\u7597\u9012\u9001\u65b9\u6848\u9762\u4e34\u7684\u6240\u6709\u6311\u6218\u3002\u6211\u4eec\u671f\u5f85\u5728\u4eca\u5e74\u7684 ESGCT \u5927\u4f1a\u4e0a\u5206\u4eab\u8fd9\u4e9b\u6210\u679c\u3002\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u9605\u8bfb\u66f4\u591a<\/strong>:\u00a0<a href=\"https:\/\/dmdwarrior.com\/zh\/dmd-therapies\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u4e34\u5e8a\u8bd5\u9a8c\uff08\u6240\u6709\u7814\u7a76\u5217\u8868\uff09<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>SonoThera, a biotechnology company dedicated to treating the root cause of human diseases by developing the next generation of genetic medicines, today announced it will present new data at the 32nd congress of the European Society of Gene and Cell Therapy being held October 7-10 in Seville, Spain. The poster presentation focuses on treating Duchenne [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4744,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[359,432,285,286],"class_list":["post-4743","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-full-length-dystrophin","tag-ripple","tag-sonothera","tag-ultrasound-mediated-delivery"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/4743","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=4743"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/4743\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/4744"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=4743"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=4743"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=4743"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}