{"id":3990,"date":"2025-06-24T12:40:44","date_gmt":"2025-06-24T09:40:44","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=3990"},"modified":"2025-06-24T12:43:56","modified_gmt":"2025-06-24T09:43:56","slug":"cumberland-ifetroban-demonstrated-improvement-compared-to-placebo-treated-patients","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/cumberland-ifetroban-demonstrated-improvement-compared-to-placebo-treated-patients\/","title":{"rendered":"\u4e0e\u63a5\u53d7\u5b89\u6170\u5242\u6cbb\u7597\u7684\u60a3\u8005\u76f8\u6bd4\uff0cCumberland \u7684 Ifetroban \u663e\u793a\u51fa 5.4% \u7684\u6539\u5584"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Cumberland Pharmaceuticals\u662f\u4e00\u5bb6\u81f4\u529b\u4e8e\u5f00\u53d1\u7f55\u89c1\u75c5\u65b0\u4ea7\u54c1\u7684\u4e13\u4e1a\u5236\u836f\u516c\u53f8\uff0c\u8be5\u516c\u53f8\u5728\u62c9\u65af\u7ef4\u52a0\u65af\u4e3e\u884c\u7684\u5bb6\u957f\u9879\u76ee\u808c\u8089\u840e\u7f29\u75c7 (PPMD) \u5e74\u5ea6\u4f1a\u8bae\u4e0a\uff0c\u5206\u4eab\u4e86\u5176\u4e8c\u671f FIGHT DMD \u8bd5\u9a8c\u7684\u6700\u65b0\u79ef\u6781\u7ed3\u679c\u3002\u8be5\u8bd5\u9a8c\u8bc4\u4f30\u4e86\u7528\u4e8e\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD) \u5fc3\u810f\u75c5\u7684\u65b0\u578b\u53e3\u670d\u836f\u7269ifetroban\u3002\u8fd9\u4e9b\u65b0\u7ed3\u679c\u7a81\u663e\u4e86ifetroban\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u5fc3\u810f\u75c5\uff08DMD \u7684\u4e3b\u8981\u6b7b\u4ea1\u539f\u56e0\uff09\u7684\u591a\u9879\u5fc3\u810f\u76ca\u5904\u6307\u6807\uff0c\u5305\u62ec\u6b64\u524d\u672a\u62a5\u544a\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u53d1\u73b0\u548c\u5fc3\u810f\u751f\u7269\u6807\u5fd7\u7269\u6570\u636e\uff0c\u8fd9\u4e9b\u6570\u636e\u8868\u660e\u8be5\u836f\u7269\u5177\u6709\u9884\u9632\u6301\u7eed\u6027\u5fc3\u810f\u635f\u5bb3\u7684\u6f5c\u529b\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u6765\u81ea\u574e\u4f2f\u5170\u7684 Ifetroban \u60a3\u8005\u6bd4\u63a5\u53d7\u5b89\u6170\u5242\u7684\u60a3\u8005\u6539\u5584\u4e86 5.4%<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3a\u671f12\u4e2a\u6708\u7684II\u671fFIGHT DMD\u8bd5\u9a8c (NCT03340675) \u8868\u660e\uff0c\u4e0e\u5b89\u6170\u5242\u7ec4\u60a3\u8005\u548c\u503e\u5411\u8bc4\u5206\u5339\u914d\u7684\u81ea\u7136\u75c5\u7a0b\u60a3\u8005\u7ec4\u6210\u7684\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0c\u9ad8\u5242\u91cf\u4f0a\u83f2\u66f2\u73ed\u6cbb\u7597\u4f7f\u5de6\u5fc3\u5ba4\u5c04\u8840\u5206\u6570 (LVEF) \u663e\u8457\u63d0\u9ad85.4%\u3002\u8fd9\u5bf9\u4e8e\u5fc3\u810f\u529f\u80fd\u901a\u5e38\u4f1a\u968f\u65f6\u95f4\u63a8\u79fb\u800c\u4e0b\u964d\u7684\u8fdb\u884c\u6027\u75be\u75c5\u800c\u8a00\uff0c\u5177\u6709\u4e34\u5e8a\u610f\u4e49\u7684\u5dee\u5f02\u3002\u2014\u2014\u4e86\u89e3\u66f4\u591a\uff1a <a href=\"https:\/\/www.clinicaltrials.gov\/study\/NCT03340675\" target=\"_blank\" rel=\"noopener\">NCT03340675<\/a> \u2013<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8be5\u7814\u7a76\u8fd8\u63ed\u793a\u4e86\u836f\u4ee3\u52a8\u529b\u5b66\u65b9\u9762\u7684\u89c1\u89e3\uff0c\u8868\u660e\u63a5\u53d7\u8f83\u9ad8\u5242\u91cf\u7684\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD) \u60a3\u8005\u8fbe\u5230\u7684\u8840\u6d46\u6d53\u5ea6\u4e0e\u666e\u901a\u6210\u5e74\u4eba\u76f8\u4f3c\uff0c\u4e14\u65e0\u836f\u7269\u84c4\u79ef\u8ff9\u8c61\uff0c\u8fd9\u652f\u6301\u9ad8\u5242\u91cf\u7ec4\u6bcf\u65e5 300 \u6beb\u514b\u7684\u7ed9\u836f\u65b9\u6848\u3002\u5c3d\u7ba1\u5242\u91cf\u8981\u6c42\u8f83\u9ad8\uff0c\u4f46\u4f0a\u83f2\u66f2\u73ed\u5728\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD) \u60a3\u8005\u4e2d\u8010\u53d7\u6027\u826f\u597d\uff0c\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u53ef\u63a5\u53d7\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ifetroban \u662f\u4ec0\u4e48\uff1f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Ifetroban \u662f\u4e00\u79cd\u6bcf\u65e5\u4e00\u6b21\u7684\u53e3\u670d\u836f\u7269\uff0c\u901a\u8fc7\u963b\u65ad\u8840\u6813\u7d20\u53d7\u4f53\u8d77\u6548\uff0c\u800c\u8840\u6813\u7d20\u53d7\u4f53\u5728\u708e\u75c7\u548c\u7ea4\u7ef4\u5316\u4e2d\u8d77\u7740\u5173\u952e\u4f5c\u7528\u3002\u8be5\u836f\u7269\u5df2\u83b7\u5f97\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\u548c\u513f\u79d1\u7f55\u89c1\u75c5\u8d44\u683c\u8ba4\u5b9a\uff0cFDA \u7528\u4e8e\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\uff08DMD\uff09\u5fc3\u810f\u75c5\u3002\u76ee\u524d\u5c1a\u65e0\u4e13\u95e8\u9488\u5bf9\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\uff08DMD\uff09\u5fc3\u810f\u75c5\u7684\u83b7\u6279\u6cbb\u7597\u836f\u7269\uff0c\u8fd9\u7a81\u663e\u4e86\u8be5\u60a3\u8005\u7fa4\u4f53\u4e9f\u5f85\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff0c\u56e0\u4e3a\u5fc3\u810f\u5e76\u53d1\u75c7\u666e\u904d\u5b58\u5728\uff0c\u662f\u5bfc\u81f4\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u9605\u8bfb\u66f4\u591a\uff1a<\/strong> <a href=\"https:\/\/dmdwarrior.com\/zh\/cumberland-pharmaceuticals-phase-2-fight-dmd-ifetroban-duchenne-trial\/\">Cumberland Pharmaceuticals \u5ba3\u5e03 DMD \u5fc3\u810f\u75c5 FIGHT Duchenne \u8bd5\u9a8c\u7b2c 2 \u671f\u53d6\u5f97\u4f18\u5f02\u7ed3\u679c<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Cumberland Pharmaceuticals a specialty pharmaceutical company committed to developing new products for rare diseases, shared the latest positive results from its Phase 2 FIGHT DMD trial evaluating ifetroban, a novel oral therapy for Duchenne muscular dystrophy (DMD) heart disease, at the annual Parent Project Muscular Dystrophy (PPMD) conference in Las Vegas. These new results highlight [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3992,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[237,238,236,239],"class_list":["post-3990","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-cumberland","tag-cumberland-pharmaceuticals","tag-dmd-heart-disease","tag-ifetroban"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/3990","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=3990"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/3990\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/3992"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=3990"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=3990"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=3990"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}