{"id":3953,"date":"2025-06-20T18:39:58","date_gmt":"2025-06-20T15:39:58","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=3953"},"modified":"2025-06-20T18:43:44","modified_gmt":"2025-06-20T15:43:44","slug":"capricor-therapeutics-announces-positive-4-year-data-of-deramiocel-cap-1002-in-duchenne-muscular-dystrophy","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/capricor-therapeutics-announces-positive-4-year-data-of-deramiocel-cap-1002-in-duchenne-muscular-dystrophy\/","title":{"rendered":"Capricor Therapeutics \u5ba3\u5e03 Deramiocel (CAP-1002) \u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684 4 \u5e74\u79ef\u6781\u6570\u636e"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Capricor Therapeutics\u662f\u4e00\u5bb6\u81f4\u529b\u4e8e\u5f00\u53d1\u8f6c\u5316\u7ec6\u80de\u548c\u5916\u6ccc\u4f53\u7597\u6cd5\u6cbb\u7597\u7f55\u89c1\u75be\u75c5\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u8be5\u516c\u53f8\u4eca\u5929\u5ba3\u5e03\uff0c\u5176\u6b63\u5728\u8fdb\u884c\u7684HOPE-2\u5f00\u653e\u6807\u7b7e\u6269\u5c55(OLE)\u7814\u7a76\u53d6\u5f97\u4e86\u79ef\u6781\u7684\u56db\u5e74\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7ed3\u679c\u3002Deramiocel\u662f\u8be5\u516c\u53f8\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7(DMD)\u7684\u9886\u5148\u7ec6\u80de\u7597\u6cd5\u5019\u9009\u836f\u7269\u3002\u2014\u2014\u9605\u8bfb\u66f4\u591a\uff1a <a href=\"https:\/\/dmdwarrior.com\/zh\/what-is-deramiocel\/\">\u4ec0\u4e48\u662f Deramiocel\uff1fCAP-1002 \u6709\u4ec0\u4e48\u4f5c\u7528\uff1f<\/a> \u2013<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7ecf\u8fc7\u56db\u5e74\u7684\u6301\u7eed\u6cbb\u7597\uff0c\u63a5\u53d7Deramiocel\u6cbb\u7597\u7684\u60a3\u8005\u4e0e\u57fa\u7ebf\u76f8\u6bd4\uff0c\u4e2d\u4f4d\u6570\u53d8\u5316\u4e3a-0.5\u5206\u3002\u6b64\u5916\uff0c\u5bf9\u57fa\u7ebfLVEF&gt;45%\u7684\u60a3\u8005\u8fdb\u884c\u7684\u4e9a\u7ec4\u5206\u6790\u663e\u793a\uff0cDeramiocel\u6cbb\u7597\u7684\u4e34\u5e8a\u83b7\u76ca\u66f4\u5927\uff0c\u652f\u6301\u65e9\u671f\u5e72\u9884Deramiocel\u4ee5\u6f5c\u5728\u5730\u4fdd\u7559\u5fc3\u810f\u529f\u80fd\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b64\u5916\uff0c\u6cbb\u7597\u7ee7\u7eed\u51cf\u7f13\u9aa8\u9abc\u808c\u75be\u75c5\u8fdb\u5c55\uff0c\u4ee5\u4e0a\u80a2\u8868\u73b0\uff08PUL v2.0\uff09\u8861\u91cf\uff0c\u60a3\u8005\u7b2c\u56db\u5e74\u7684\u5e73\u5747\u4e0b\u964d\u5e45\u5ea6\uff080.6 \u5206\uff09\u4e0e\u7b2c\u4e00\u5e74\uff081.8 \u5206\uff09\u76f8\u6bd4\u8f83\u5c0f\u3002 <strong>\u603b\u4e4b\uff0c\u8fd9\u4e9b\u53d1\u73b0\u8868\u660e\uff0c\u957f\u671f\u4f7f\u7528 Deramiocel \u6cbb\u7597\u53ef\u80fd\u6709\u52a9\u4e8e\u51cf\u7f13 DMD \u7684\u8fdb\u5c55\u3002<\/strong> Deramiocel \u5728\u6574\u4e2a\u7814\u7a76\u8fc7\u7a0b\u4e2d\u6301\u7eed\u4fdd\u6301\u826f\u597d\u7684\u5b89\u5168\u6027\u3002\u2013 \u4e86\u89e3\u66f4\u591a\uff1a <a href=\"https:\/\/dmdwarrior.com\/zh\/capricor-therapeutics-deramiocel-mid-cycle-review-meeting-with-fda\/\">Capricor Therapeutics \u5ba3\u5e03\u5b8c\u6210\u4e0e FDA \u5c31 Deramiocel \u8fdb\u884c\u7684\u4e2d\u671f\u5ba1\u67e5\u4f1a\u8bae<\/a> \u2013<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">PPMD \u521b\u59cb\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98 Pat Furlong \u8868\u793a\uff1a\u201c\u5fc3\u808c\u75c5\u4ecd\u7136\u662f\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u4e3b\u8981\u6b7b\u56e0\u4e4b\u4e00\uff0c\u89e3\u51b3\u8be5\u75be\u75c5\u7684\u8fd9\u4e00\u65b9\u9762\u5bf9\u4e8e\u6539\u5584\u9884\u540e\u81f3\u5173\u91cd\u8981\u3002HOPE-2 OLE \u7814\u7a76\u7684\u957f\u671f\u6570\u636e\u4ee4\u4eba\u9f13\u821e\uff0c\u5c24\u5176\u4f53\u73b0\u5728\u56db\u5e74\u5185\u5fc3\u810f\u4fdd\u6301\u7a33\u5b9a\u3002Deramiocel \u4ee3\u8868\u4e86\u4e00\u79cd\u91cd\u8981\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u6211\u4eec\u652f\u6301\u901a\u8fc7\u76d1\u7ba1\u9014\u5f84\u6301\u7eed\u53d6\u5f97\u8fdb\u5c55\uff0c\u4ee5\u786e\u4fdd\u9488\u5bf9\u5fc3\u810f\u548c\u808c\u8089\u529f\u80fd\u7684\u6cbb\u7597\u80fd\u591f\u5c3d\u5feb\u60e0\u53ca\u6211\u4eec\u7684\u793e\u533a\u3002\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Capricor Therapeutics \u9996\u5e2d\u6267\u884c\u5b98 Linda Marb\u00e1n \u535a\u58eb\u8868\u793a\uff1a\u201c\u8fd9\u4e9b\u56db\u5e74\u7684\u6570\u636e\u8fdb\u4e00\u6b65\u8bc1\u660e\u4e86 Deramiocel \u5728\u5fc3\u810f\u548c\u9aa8\u9abc\u808c\u529f\u80fd\u65b9\u9762\u4e34\u5e8a\u76ca\u5904\u7684\u5f3a\u5ea6\u548c\u6301\u4e45\u6027\uff0c\u4ee5\u53ca\u826f\u597d\u7684\u5b89\u5168\u6027\u3002\u6211\u4eec\u7684\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7 (BLA) \u5df2\u83b7\u5f97\u4f18\u5148\u5ba1\u8bc4\uff0c\u4e14\u591a\u9879\u5173\u952e\u76d1\u7ba1\u6b65\u9aa4\u5df2\u5b8c\u6210\uff0c\u6211\u4eec\u6b63\u5168\u529b\u4ee5\u8d74\u3001\u523b\u4e0d\u5bb9\u7f13\u5730\u63a8\u8fdb\uff0c\u4e89\u53d6\u83b7\u5f97\u6f5c\u5728\u6279\u51c6\u3002\u6211\u4eec\u4e0e FDA \u7684\u6301\u7eed\u6c9f\u901a\u4ecd\u5728\u8fdb\u884c\u4e2d\uff0c\u6ca1\u6709\u4efb\u4f55\u5ef6\u8bef\u7684\u8ff9\u8c61\u3002\u6211\u4eec\u611f\u8c22\u6240\u6709\u4e3a\u63a8\u8fdb\u8be5\u9879\u76ee\u505a\u51fa\u8d21\u732e\u7684\u60a3\u8005\u3001\u5bb6\u5c5e\u548c\u4e34\u5e8a\u533b\u751f\u3002\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9605\u8bfb\u66f4\u591a\uff1a <a href=\"https:\/\/dmdwarrior.com\/zh\/capricor-therapeutics-announces-bmd-orphan-drug-designation-and-dmd-program-regulatory-development-for-deramiocel-cap-1002\/\">Capricor Therapeutics \u5ba3\u5e03\u83b7\u5f97 BMD \u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff0c\u5e76\u542f\u52a8 Deramiocel (CAP-1002) \u7684 DMD \u9879\u76ee\u76d1\u7ba1\u5f00\u53d1<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Capricor Therapeutics, a biotechnology company developing transformative cell and exosome-based therapeutics for rare diseases, today announced positive four-year safety and efficacy results from its ongoing HOPE-2 Open-Label Extension (OLE) study of Deramiocel, the Company\u2019s lead cell therapy candidate for Duchenne Muscular Dystrophy (DMD). &#8211; Read More: What is Deramiocel? What Does CAP-1002 Do? &#8211; After [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3954,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[90,86,87,89,85,362,301],"class_list":["post-3953","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-cap-1002","tag-capricor","tag-capricor-therapeutics","tag-cardiomyopathy","tag-deramiocel","tag-dmd-cardiomyopathy","tag-hope-2"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/3953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=3953"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/3953\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/3954"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=3953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=3953"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=3953"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}