{"id":3872,"date":"2025-05-22T18:37:53","date_gmt":"2025-05-22T15:37:53","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=3872"},"modified":"2025-05-22T18:37:55","modified_gmt":"2025-05-22T15:37:55","slug":"entos-pharmaceuticals-develops-re-dosable-full-length-dystrophin-gene-therapy-fusogenix-plv-method","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/entos-pharmaceuticals-develops-re-dosable-full-length-dystrophin-gene-therapy-fusogenix-plv-method\/","title":{"rendered":"Entos Pharmaceuticals \u5f00\u53d1\u53ef\u91cd\u590d\u7ed9\u836f\u7684\u5168\u957f\u808c\u8425\u517b\u4e0d\u826f\u86cb\u767d\u57fa\u56e0\u7597\u6cd5\uff1aFusogenix PLV \u65b9\u6cd5"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Entos Pharmaceuticals Inc.\uff08Entos\uff09\u662f\u4e00\u5bb6\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u5229\u7528\u5176\u975e\u75c5\u6bd2\u3001\u53ef\u91cd\u590d\u7ed9\u836f\u7684Fusogenix PLV\u9012\u9001\u6280\u672f\u7814\u53d1\u57fa\u56e0\u7597\u6cd5\u3002CureDuchenne Ventures\u5ba3\u5e03\u5411Entos\u63d0\u4f9b1.02\u4ebf\u7f8e\u5143\u7684\u521d\u59cb\u6295\u8d44\u3002\u4e3a\u4e86\u6cbb\u6108\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\uff08DMD\uff09\uff0cEntos\u5c06\u5229\u7528\u8fd9\u7b14\u878d\u8d44\u5f00\u53d1\u4e00\u79cd\u9012\u9001\u5168\u957f\u6297\u808c\u840e\u7f29\u86cb\u767d\u7684\u808c\u8089\u9776\u5411\u7597\u6cd5\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CureDuchenne Ventures \u6295\u8d44 Entos Pharmaceuticals<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CureDuchenne \u521b\u59cb\u4eba\u517c\u9996\u5e2d\u6267\u884c\u5b98 Debra Miller \u8868\u793a\uff1a\u201c\u6211\u4eec\u5bf9 Entos Pharmaceuticals \u6280\u672f\u7684\u6f5c\u529b\u611f\u5230\u975e\u5e38\u5174\u594b\uff0c\u5e76\u671f\u5f85\u4e0e Entos \u5408\u4f5c\u5f00\u53d1\u4e00\u79cd\u80fd\u591f\u514b\u670d\u5f53\u524d\u57fa\u4e8e AAV \u7684\u65b9\u6cd5\u7684\u5c40\u9650\u6027\u7684\u57fa\u56e0\u7597\u6cd5\u2014\u2014\u8fd9\u79cd\u7597\u6cd5\u4e0d\u4f1a\u6392\u9664\u5177\u6709\u9884\u5148\u5b58\u5728\u514d\u75ab\u529b\u7684\u4e2a\u4f53\uff0c\u5141\u8bb8\u91cd\u590d\u7ed9\u836f\uff0c\u5e76\u4e14\u81f3\u5173\u91cd\u8981\u7684\u662f\uff0c\u5c06\u5168\u957f\u808c\u8425\u517b\u4e0d\u826f\u86cb\u767d\u8f93\u9001\u5230\u6240\u6709\u5fc5\u8981\u7684\u808c\u8089\u7ec4\u7ec7\u3002\u201d <a href=\"https:\/\/entospharma.com\/technology\" target=\"_blank\" rel=\"noreferrer noopener\">Fusogenix PLV<\/a> \u2013<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CureDuchenne \u957f\u671f\u4ee5\u6765\u4e00\u76f4\u662f\u8d44\u52a9\u521b\u65b0\u6cbb\u7597\u65b9\u6cd5\u7684\u9886\u5bfc\u8005\uff0c\u8fd9\u9879\u6295\u8d44\u5f70\u663e\u4e86\u6211\u4eec\u6301\u7eed\u8fd0\u7528\u98ce\u9669\u6148\u5584\u4e8b\u4e1a\uff0c\u63a8\u52a8\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u53d8\u9769\u6027\u6cbb\u7597\u8fdb\u5c55\u3002\u6211\u4eec\u5411\u6350\u8d60\u8005\u548c\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u60a3\u8005\u7fa4\u4f53\u81f4\u4ee5\u8877\u5fc3\u7684\u611f\u8c22\u2014\u2014\u662f\u4f60\u4eec\u7684\u652f\u6301\u4f7f\u8fd9\u9879\u6295\u8d44\u6210\u4e3a\u53ef\u80fd\uff0c\u5e76\u5c06\u7ee7\u7eed\u63a8\u52a8\u6cbb\u6108\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u8fdb\u7a0b\u3002\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fusogenix PLV \u662f\u4ec0\u4e48<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Fusogenix PLV \u9012\u9001\u5e73\u53f0\u91c7\u7528\u6211\u4eec\u4e13\u6709\u7684\u878d\u5408 FAST \u86cb\u767d\u914d\u5236\u800c\u6210\uff0c\u53ef\u9a71\u52a8\u6cbb\u7597\u6027\u6838\u9178\u6709\u6548\u8f7d\u8377\u878d\u5408\u5e76\u5411\u5168\u8eab\u7ec6\u80de\u548c\u7ec4\u7ec7\u9012\u9001\uff0c\u4ece\u800c\u4f7f\u8fd9\u4e9b\u6025\u9700\u7684\u6cbb\u7597\u65b9\u6cd5\u6210\u4e3a\u73b0\u5b9e\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Entos Pharmaceuticals \u9996\u5e2d\u6267\u884c\u5b98 John Lewis \u8868\u793a\uff1a\u201cFusogenix PLV \u5e73\u53f0\u80fd\u591f\u5b89\u5168\u3001\u6709\u6548\u4e14\u53ef\u91cd\u590d\u5730\u5c06\u5168\u957f\u529f\u80fd\u6027\u57fa\u56e0\uff08\u4f8b\u5982\u808c\u8425\u517b\u4e0d\u826f\u86cb\u767d\uff09\u9012\u9001\u81f3\u5168\u8eab\u808c\u8089\u7ec6\u80de\u3002\u9274\u4e8e Fusogenix PLV \u7597\u6cd5\u53ef\u4ee5\u6839\u636e\u9700\u8981\u8fdb\u884c\u591a\u6b21\u7ed9\u836f\uff0c\u8fd9\u53ef\u80fd\u4f1a\u5e26\u6765\u771f\u6b63\u7684\u53d8\u9769\u3002\u6211\u4eec\u5e0c\u671b\u8fd9\u79cd\u65b9\u6cd5\u80fd\u591f\u4e3a\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u60a3\u8005\u53ca\u5176\u5bb6\u4eba\u5e26\u6765\u771f\u6b63\u7684\u6539\u53d8\u3002\u201d<\/p>","protected":false},"excerpt":{"rendered":"<p>Entos Pharmaceuticals Inc. (Entos) is a biotech business that creates genetic therapies using its non-viral, redosable Fusogenix PLV delivery technology. CureDuchenne Ventures announced an initial $1 million investment in Entos. In order to cure Duchenne muscular dystrophy (DMD), Entos will use this financing to develop a muscle-targeting therapy that delivers full-length dystrophin. CureDuchenne Ventures Invests [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3873,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[369,359,370,61],"class_list":["post-3872","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-entos-pharmaceuticals","tag-full-length-dystrophin","tag-fusogenix-plv","tag-gene-therapy"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/3872","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=3872"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/3872\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/3873"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=3872"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=3872"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=3872"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}