{"id":3802,"date":"2025-05-05T17:54:31","date_gmt":"2025-05-05T14:54:31","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=3802"},"modified":"2025-05-05T17:55:03","modified_gmt":"2025-05-05T14:55:03","slug":"scribe-therapeutics-and-prevail-therapeutics-to-share-in-vivo-crispr-based-genome-editing-data-at-asgct-2025","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/scribe-therapeutics-and-prevail-therapeutics-to-share-in-vivo-crispr-based-genome-editing-data-at-asgct-2025\/","title":{"rendered":"Scribe Therapeutics \u548c Prevail Therapeutics \u5c06\u5728 ASGCT 2025 \u4e0a\u5206\u4eab\u57fa\u4e8e CRISPR \u7684\u4f53\u5185\u57fa\u56e0\u7ec4\u7f16\u8f91\u6570\u636e"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Scribe Therapeutics \u662f\u4e00\u5bb6\u81f4\u529b\u4e8e\u91ca\u653e CRISPR \u6539\u53d8\u4eba\u7c7b\u5065\u5eb7\u7684\u6f5c\u529b\u7684\u57fa\u56e0\u836f\u7269\u516c\u53f8\uff0c\u8be5\u516c\u53f8\u4eca\u5929\u5ba3\u5e03\u5c06\u53c2\u52a0 2025 \u5e74 5 \u6708 13 \u65e5\u81f3 17 \u65e5\u5728\u8def\u6613\u65af\u5b89\u90a3\u5dde\u65b0\u5965\u5c14\u826f Ernest N. Morial \u4f1a\u8bae\u4e2d\u5fc3\u4e3e\u884c\u7684\u7b2c 28 \u5c4a\u7f8e\u56fd\u57fa\u56e0\u548c\u7ec6\u80de\u6cbb\u7597\u5b66\u4f1a (ASGCT) \u5e74\u4f1a\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Scribe Therapeutics \u5c06\u8fdb\u884c\u4e24\u573a\u6f14\u8bb2\uff0c\u5c55\u793a\u8be5\u516c\u53f8\u5229\u7528 CRISPR \u65b9\u6cd5\u8bbe\u8ba1\u65b0\u578b\u4f53\u5185\u57fa\u56e0\u836f\u7269\u6240\u53d6\u5f97\u7684\u6301\u7eed\u8fdb\u5c55\u3002<\/strong> \u5728\u4e00\u9879\u5f3a\u6548\u6cbb\u7597\u5e94\u7528\u6f14\u793a\u4e2d\uff0cScribe Therapeutics \u5c06\u5c55\u793a\u5176\u5229\u7528 X-Editor (XE) \u6280\u672f\u9776\u5411\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD) \u7a81\u53d8\u7684\u65b0\u578b\u57fa\u56e0\u7ec4\u7f16\u8f91\u7b56\u7565\u3002\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u662f\u4e00\u79cd\u4e25\u91cd\u7684\u795e\u7ecf\u808c\u8089\u75be\u75c5\uff0c\u53ef\u5bfc\u81f4\u547c\u5438\u8870\u7aed\u548c\u5fc3\u810f\u8870\u7aed\u3002\u8fd9\u9879\u7814\u7a76\u7684\u7ed3\u679c\u5c06\u5c55\u793a XE \u4f5c\u4e3a\u6cbb\u7597 DMD \u548c\u5176\u4ed6\u9057\u4f20\u6027\u808c\u8089\u75be\u75c5\u7684\u6709\u6548\u591a\u529f\u80fd\u5e73\u53f0\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b64\u6b21\u8054\u5408\u6f14\u8bb2\u5c06\u4ecb\u7ecd\u793c\u6765\u516c\u53f8\u5168\u8d44\u5b50\u516c\u53f8Scribe Therapeutics\u548cPrevail Therapeutics\u7684\u7814\u7a76\u6210\u679c\uff0c\u4ed6\u4eec\u81f4\u529b\u4e8e\u8bbe\u8ba1\u81ea\u5931\u6d3b\u817a\u76f8\u5173\u75c5\u6bd2(AAV)\u8f7d\u4f53\uff0c\u8be5\u8f7d\u4f53\u4ee5Scribe Therapeutics\u57fa\u4e8eCRISPR\u6280\u672f\u7684XE\u57fa\u56e0\u4e3a\u8f7d\u4f53\uff0c\u5e76\u7ed3\u5408\u81ea\u9776\u5411\u5411\u5bfcRNA\uff0c\u5e76\u5c55\u793a\u4e86\u5728\u5c0f\u9f20\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u4e2d\u5b9e\u73b0\u5f3a\u6548\u3001\u77ac\u65f6\u4e14\u53ef\u63a7\u7684\u4f53\u5185\u9776\u5411\u7f16\u8f91\u7684\u6548\u679c\u3002\u4e24\u5bb6\u516c\u53f8\u8fd1\u671f\u5728\u795e\u7ecf\u7cfb\u7edf\u548c\u795e\u7ecf\u808c\u8089\u75be\u75c5\u9886\u57df\u7684\u5408\u4f5c\u4e2d\u53d6\u5f97\u4e86\u91cc\u7a0b\u7891\u5f0f\u7684\u6210\u529f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9605\u8bfb\u66f4\u591a\uff1a <a href=\"https:\/\/dmdwarrior.com\/zh\/new-gene-therapies-for-duchenne-muscular-dystrophy\/\">\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u65b0\u57fa\u56e0\u7597\u6cd5<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Scribe Therapeutics, a genetic medicines company unlocking the potential of CRISPR to transform human health, today announced its participation in the 28th American Society of Gene &amp; Cell Therapy (ASGCT) Annual Meeting taking place May 13-17, 2025, at the Ernest N. Morial Convention Center in New Orleans, LA. Scribe Therapeutics will deliver two presentations that [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3803,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[366,290,72,61,365,364,363],"class_list":["post-3802","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-asgct-2025","tag-crispr","tag-gene-editing","tag-gene-therapy","tag-genome-editing","tag-prevail-therapeutics","tag-scribe-therapeutics"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/3802","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=3802"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/3802\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/3803"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=3802"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=3802"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=3802"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}