{"id":2785,"date":"2025-02-03T15:39:17","date_gmt":"2025-02-03T12:39:17","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2785"},"modified":"2025-03-07T13:17:20","modified_gmt":"2025-03-07T10:17:20","slug":"entrada-therapeutics-receives-uk-authorization-to-begin-elevate-44-201","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/entrada-therapeutics-receives-uk-authorization-to-begin-elevate-44-201\/","title":{"rendered":"Entrada Therapeutics \u83b7\u5f97\u82f1\u56fd\u6388\u6743\u5f00\u59cb ELEVATE-44-201"},"content":{"rendered":"<p class=\"wp-block-paragraph\">ELEVATE-44-201 \u662f ENTR-601-44 \u7684 1\/2 \u671f\u591a\u6b21\u9012\u589e\u5242\u91cf (MAD) \u4e34\u5e8a\u7814\u7a76\uff0c\u5df2\u83b7\u5f97\u82f1\u56fd\u836f\u54c1\u548c\u4fdd\u5065\u4ea7\u54c1\u7ba1\u7406\u5c40 (MHRA) \u548c\u7814\u7a76\u4f26\u7406\u59d4\u5458\u4f1a\u7684\u6279\u51c6\uff0c\u7528\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u3002\u8be5\u7814\u7a76\u65e8\u5728\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD)\uff0c\u9002\u7528\u4e8e\u5df2\u786e\u8ba4 DMD \u57fa\u56e0\u7a81\u53d8\u4e14\u53ef\u901a\u8fc7\u5916\u663e\u5b50 44 \u8df3\u8dc3\u6cbb\u7597\u7684\u60a3\u8005\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u4ec0\u4e48\u662fELEVATE-44-201 \u4e34\u5e8a\u7814\u7a76\uff1f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">ELEVATE-44-201 \u662f\u4e00\u9879\u5168\u7403\u6027\u3001\u4e24\u90e8\u5206\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684 1\/2 \u671f\u7814\u7a76\uff0c\u8bc4\u4f30\u4e86 ENTR-601-44 \u5bf9\u9002\u5408\u8fdb\u884c\u5916\u663e\u5b50 44 \u8df3\u8dc3\u6cbb\u7597\u7684 DMD \u95e8\u8bca\u60a3\u8005\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u6709\u6548\u6027\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>ELEVATE-44-201, a Phase 1\/2 multiple ascending dose (MAD) clinical study of ENTR-601-44, was authorized by the UK&#8217;s Medicines and Healthcare Products Regulatory Agency (MHRA) and Research Ethics Committee for the Clinical Trial of an Investigational Medicinal Product. The study aims to treat Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation in the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2788,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[235,49,233,234,141,127,77,48],"class_list":["post-2785","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-elevate-44-201","tag-england","tag-entrada","tag-entrada-therapeutics","tag-exon-44","tag-exon-44-skipping","tag-exon-skipping","tag-uk"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2785","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=2785"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2785\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/2788"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=2785"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=2785"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=2785"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}