{"id":2612,"date":"2025-01-27T11:49:18","date_gmt":"2025-01-27T08:49:18","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2612"},"modified":"2025-01-27T14:06:33","modified_gmt":"2025-01-27T11:06:33","slug":"roche-announces-new-results-from-the-embark-study-of-elevidys-in-outpatients-with-duchenne-muscular-dystrophy-dmd","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/roche-announces-new-results-from-the-embark-study-of-elevidys-in-outpatients-with-duchenne-muscular-dystrophy-dmd\/","title":{"rendered":"\u7f57\u6c0f\u516c\u5e03 EMBARK \u7814\u7a76\u65b0\u7ed3\u679c\uff0c\u8be5\u7814\u7a76\u9488\u5bf9\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD) \u95e8\u8bca\u60a3\u8005\u8fdb\u884c\u4e86 Elevidys \u6cbb\u7597"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u4eca\u5929\uff0c\u7f57\u6c0f\u516c\u53f8\u516c\u5e03\u4e86 EMBARK \u8bd5\u9a8c\u7b2c\u4e8c\u5e74\u4ee4\u4eba\u9f13\u821e\u7684\u9876\u7ebf\u6570\u636e\uff0c\u8be5\u8bd5\u9a8c\u662f\u9488\u5bf9 Elevidys\uff08delandistrogene moxeparvovec\uff09\u7684\u4e00\u9879\u5168\u7403\u6027\u3001\u53cc\u76f2\u3001\u968f\u673a III \u671f\u7814\u7a76\uff0c\u4e5f\u662f\u9996\u4e2a\u83b7\u51c6\u7528\u4e8e\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u57fa\u56e0\u7597\u6cd5\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e0e\u9884\u5148\u786e\u5b9a\u7684\u503e\u5411\u52a0\u6743\u672a\u6cbb\u7597\u7684\u5916\u90e8\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0cElevidys \u6cbb\u7597\u4e24\u5e74\u540e\uff0c\u4e09\u9879\u91cd\u8981\u7684\u8fd0\u52a8\u529f\u80fd\u6d4b\u8bd5\u4e2d\u51fa\u73b0\u4e86\u7edf\u8ba1\u5b66\u4e0a\u663e\u8457\u4e14\u5177\u6709\u4e34\u5e8a\u610f\u4e49\u7684\u6539\u5584\uff1aNSAA\u3001TTR \u548c 10MWR\u3002\u5728\u670d\u836f\u540e\u4e00\u5230\u4e24\u5e74\u5185\uff0c\u63a5\u53d7 Elevidys \u6cbb\u7597\u7684\u60a3\u8005\u4e0e\u5916\u90e8\u5bf9\u7167\u7ec4\u4e4b\u95f4\u7684\u529f\u80fd\u5dee\u5f02\u6709\u6240\u6269\u5927\u3002\u4ece\u6574\u4f53\u6765\u770b\uff0c\u8fd9\u4e9b\u53d1\u73b0\u8868\u660e Elevidys \u4e00\u76f4\u53d7\u76ca\u532a\u6d45\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7f57\u6c0f\u9996\u5e2d\u533b\u7597\u5b98\u517c\u5168\u7403\u4ea7\u54c1\u5f00\u53d1\u4e3b\u7ba1 Levi Garraway \u533b\u5b66\u535a\u58eb\u8868\u793a\uff1a\u201c\u7ecf\u8fc7\u4e24\u5e74\u7684 Elevidys \u6cbb\u7597\uff0c\u6211\u4eec\u770b\u5230\u8fd9\u4e9b\u5c0f\u7537\u5b69\u7684\u65e5\u5e38\u751f\u6d3b\u4e2d\u51fa\u73b0\u4e86\u591a\u79cd\u6301\u7eed\u76ca\u5904\uff0c\u6240\u6709\u8fd9\u4e9b\u90fd\u8868\u660e\u8be5\u836f\u7269\u5177\u6709\u6539\u5584\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u6f5c\u529b\u3002\u8fd9\u4e9b\u7ed3\u679c\u5305\u62ec\u7ad9\u7acb\u3001\u884c\u8d70\u548c\u8dd1\u6b65\u65b9\u9762\u7684\u6539\u5584\uff0c\u4ee3\u8868\u7740\u6709\u610f\u4e49\u7684\u8fdb\u5c55\uff0c\u6211\u4eec\u8ba1\u5212\u5c3d\u5feb\u4e0e\u536b\u751f\u5f53\u5c40\u5206\u4eab\u8fd9\u4e9b\u7ed3\u679c\u3002\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u9605\u8bfb\u66f4\u591a\uff1a<\/strong> <a href=\"https:\/\/dmdwarrior.com\/zh\/frequently-asked-questions-about-elevidys-used-for-duchenne-muscular-dystrophy\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u5173\u4e8e Elevidys \u7684\u5e38\u89c1\u95ee\u9898\u89e3\u7b54<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Today, Roche revealed encouraging topline data from the second year of the EMBARK trial, a worldwide, double-blind, randomised phase III investigation of Elevidys (delandistrogene moxeparvovec), the first gene therapy to be authorized for the treatment of Duchenne muscular dystrophy. When compared to a predetermined propensity-weighted untreated external control group, statistically significant and clinically meaningful improvements [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2613,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[66,33,207,61,203,65],"class_list":["post-2612","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-duchenne-muscular-dystrophy","tag-elevidys","tag-embark","tag-gene-therapy","tag-roche","tag-sarepta"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2612","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=2612"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2612\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/2613"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=2612"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=2612"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=2612"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}