{"id":2390,"date":"2025-01-16T13:22:01","date_gmt":"2025-01-16T10:22:01","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2390"},"modified":"2025-01-16T13:22:02","modified_gmt":"2025-01-16T10:22:02","slug":"insmeds-gene-therapy-ins1201-poised-to-challenge-duchenne-muscular-dystrophy-dmd","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/insmeds-gene-therapy-ins1201-poised-to-challenge-duchenne-muscular-dystrophy-dmd\/","title":{"rendered":"Insmed \u57fa\u56e0\u7597\u6cd5 (INS1201) \u6709\u671b\u6311\u6218\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD)"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Insmed \u6b63\u51c6\u5907\u4f7f\u7528\u5176\u7a81\u7834\u6027\u7684\u57fa\u56e0\u7597\u6cd5 INS1201 \u6765\u5bf9\u6297\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u3002\u5728 FDA \u4e8e 2024 \u5e74 12 \u6708\u6279\u51c6\u5176\u8bd5\u9a8c\u6027\u65b0\u836f (IND) \u7533\u8bf7\u540e\uff0cInsmed \u6253\u7b97\u5728 2025 \u5e74\u4e0a\u534a\u5e74\u542f\u52a8 INS1201 \u7684 I \u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u4ec0\u4e48\u662f Insmed INS1201 \u57fa\u56e0\u6cbb\u7597\uff1f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">INS1201 \u76f4\u63a5\u4f5c\u7528\u4e8e\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\uff0c\u901a\u8fc7\u9798\u5185\u7ed9\u836f\uff0c\u800c Elevidys \u5219\u9700\u8981\u5168\u8eab\u9759\u8109\u6ce8\u5c04\u3002\u8fd9\u79cd\u6709\u9488\u5bf9\u6027\u7684\u7ed9\u836f\u7b56\u7565\u65e8\u5728\u89e3\u51b3\u5168\u8eab\u57fa\u56e0\u6cbb\u7597\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u95ee\u9898\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9798\u5185\u7ed9\u836f\u53ef\u5c06\u6240\u9700\u5242\u91cf\u5927\u5e45\u964d\u4f4e 10 \u81f3 50 \u500d\uff0c\u901a\u8fc7\u5c06\u836f\u7269\u96c6\u4e2d\u5728\u9700\u8981\u7684\u5730\u65b9\uff0c\u53ef\u9632\u6b62\u5168\u8eab\u6bd2\u6027\u548c\u8131\u9776\u6548\u5e94\u3002\u5c3d\u7ba1\u5b58\u5728\u810a\u9ad3\u635f\u4f24\u3001\u795e\u7ecf\u635f\u4f24\u548c\u611f\u67d3\u98ce\u9669\u7b49\u969c\u788d\uff0c\u4f46\u8fd9\u53ef\u80fd\u4e3a\u60a3\u8005\u63d0\u4f9b\u66f4\u5b89\u5168\u3001\u66f4\u6210\u529f\u7684\u9009\u62e9\uff0c\u5c24\u5176\u662f\u8003\u8651\u5230\u9759\u8109\u6cbb\u7597\u4e2d\u4f7f\u7528\u7684\u5927\u5242\u91cf\u75c5\u6bd2\u8f7d\u4f53\u7684\u5b89\u5168\u95ee\u9898\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e86\u89e3\u66f4\u591a\uff1a<\/strong> <a href=\"https:\/\/dmdwarrior.com\/zh\/new-gene-therapies-for-duchenne-muscular-dystrophy\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u6f5c\u5728\u65b0\u57fa\u56e0\u7597\u6cd5<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Insmed is getting ready to use its ground-breaking gene therapy, INS1201, to combat Duchenne muscular dystrophy. Insmed intends to start Phase I clinical trials for INS1201 in the first half of 2025 after the FDA approved its investigational new drug (IND) application in December 2024. What is Insmed INS1201 Gene Therapy? INS1201 targets the central [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2465,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[66,72,61,173,174,172],"class_list":["post-2390","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-duchenne-muscular-dystrophy","tag-gene-editing","tag-gene-therapy","tag-ins1201","tag-ins1201-gene-therapy","tag-insmed"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2390","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=2390"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2390\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/2465"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=2390"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=2390"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=2390"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}