{"id":2355,"date":"2025-01-08T17:41:32","date_gmt":"2025-01-08T14:41:32","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2355"},"modified":"2025-03-07T15:26:36","modified_gmt":"2025-03-07T12:26:36","slug":"avidity-biosciences-prepares-for-three-rare-muscle-disease-programs-2025-bla-submission-and-commercialization","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/avidity-biosciences-prepares-for-three-rare-muscle-disease-programs-2025-bla-submission-and-commercialization\/","title":{"rendered":"Avidity Biosciences \u4e3a\u4e09\u9879\u7f55\u89c1\u808c\u8089\u75be\u75c5\u9879\u76ee 2025 \u5e74 BLA \u63d0\u4ea4\u548c\u5546\u4e1a\u5316\u505a\u51c6\u5907"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Avidity Biosciences, Inc. \u662f\u4e00\u5bb6\u81f4\u529b\u4e8e\u5f00\u53d1\u4e00\u79cd\u540d\u4e3a\u6297\u4f53\u5be1\u6838\u82f7\u9178\u5076\u8054\u7269 (AOCsTM) \u7684\u65b0\u578b RNA \u6cbb\u7597\u65b9\u6cd5\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4eca\u5929\u62a5\u544a\u4e86\u5176\u8fdb\u5c55\u548c 2025 \u5e74\u6539\u53d8\u6e38\u620f\u89c4\u5219\u7684\u8ba1\u5212\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fd9\u4e9b\u91cd\u8981\u7684\u9884\u671f\u91cc\u7a0b\u7891\u5305\u62ec\u5b8c\u6210\u4e09\u4e2a\u6f5c\u5728\u7684\u6ce8\u518c\u9879\u76ee\u3001\u4e3a\u60a3\u6709\u53ef\u901a\u8fc7\u5916\u663e\u5b5044\u8df3\u8dc3\u6cbb\u7597\u7684\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD44) \u7a81\u53d8\u7684\u60a3\u8005\u63d0\u4ea4 delpacibart zotadirsen (del-zota) \u7684\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7 (BLA)\u3001\u4e3a DMD44\u30011 \u578b\u5f3a\u76f4\u6027\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DM1) \u548c\u9762\u80a9\u80b1\u578b\u808c\u8425\u517b\u4e0d\u826f\u75c7 (FSHD) \u7684\u51e0\u79cd\u4ea7\u54c1\u4e0a\u5e02\u505a\u597d\u51c6\u5907\uff0c\u5e76\u5efa\u7acb\u4e00\u4e2a\u5b8c\u5168\u6574\u5408\u7684\u56fd\u9645\u4e1a\u52a1\uff0c\u4ee5\u652f\u6301\u7cbe\u51c6\u5fc3\u810f\u75c5\u5b66\u548c\u795e\u7ecf\u808c\u8089\u75be\u75c5\u9886\u57df\u4e0d\u65ad\u6269\u5927\u7684 AOC \u7ba1\u7ebf\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>A biopharmaceutical firm dedicated to developing a novel class of RNA treatments known as Antibody Oligonucleotide Conjugates (AOCsTM), Avidity Biosciences, Inc., today reported its advancements and plans for a game-changing year in 2025. These significant expected milestones include completing three potentially registrational programs, submitting a Biologics License Application (BLA) for delpacibart zotadirsen (del-zota) for individuals [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2357,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[126,128,130,129,66,77],"class_list":["post-2355","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-avidity-biosciences","tag-bla","tag-dm1","tag-dmd44","tag-duchenne-muscular-dystrophy","tag-exon-skipping"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2355","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=2355"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2355\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/2357"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=2355"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=2355"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=2355"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}