{"id":2190,"date":"2025-01-02T01:50:35","date_gmt":"2025-01-01T22:50:35","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2190"},"modified":"2025-01-02T02:00:28","modified_gmt":"2025-01-01T23:00:28","slug":"is-duchenne-gene-therapy-a-suitable-treatment-despite-its-immunogenic-class-effect","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/is-duchenne-gene-therapy-a-suitable-treatment-despite-its-immunogenic-class-effect\/","title":{"rendered":"\u5c3d\u7ba1\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u57fa\u56e0\u7597\u6cd5\u5177\u6709\u514d\u75ab\u539f\u6027\u7c7b\u6548\u5e94\uff0c\u4f46\u5b83\u662f\u5426\u662f\u4e00\u79cd\u5408\u9002\u7684\u6cbb\u7597\u65b9\u6cd5\uff1f"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7 (DMD) \u662f\u4e00\u79cd\u4e25\u91cd\u7684 X \u8fde\u9501\u75be\u75c5\uff0c\u5176\u7279\u5f81\u662f\u808c\u8089\u9010\u6e10\u65e0\u529b\uff0c\u6700\u7ec8\u56e0\u5fc3\u808c\u75c5\u6216\u547c\u5438\u7cfb\u7edf\u5e76\u53d1\u75c7\u800c\u6b7b\u4ea1\u3002\u76ee\u524d\uff0c\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u5c1a\u65e0\u6cbb\u6108\u65b9\u6cd5\uff0c\u6807\u51c6\u6cbb\u7597\u7684\u4e3b\u8981\u91cd\u70b9\u662f\u75c7\u72b6\u7ba1\u7406\u3002\u57fa\u56e0\u7597\u6cd5\u53ef\u4ee5\u901a\u8fc7\u91c7\u7528\u514d\u75ab\u6291\u5236\u63aa\u65bd\u548c\u4f18\u5316\u8f7d\u4f53\u8bbe\u8ba1\u66f4\u6709\u6548\u5730\u89e3\u51b3\u8be5\u75be\u75c5\u7684\u9057\u4f20\u539f\u56e0\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u57fa\u56e0\u6cbb\u7597\u5bf9\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\uff08DMD\uff09\u6709\u4ec0\u4e48\u4f5c\u7528\uff1f\u57fa\u56e0\u6cbb\u7597\u6709\u6548\u5417\uff1f\u4e0b\u9762\u6211\u4eec\u6765\u5168\u9762\u5206\u6790\u4e00\u4e0b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.tandfonline.com\/eprint\/BFZQKYN3YY3AHAVX9S27\/full?target=10.1080\/14740338.2024.2447072\" target=\"_blank\" rel=\"noreferrer noopener\">\u9605\u8bfb\u66f4\u591a<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/x.com\/ToshifumiYokota\" target=\"_blank\" rel=\"noreferrer noopener\">\u5173\u6ce8 Toshi Yokota \u6559\u6388<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Progressive muscle weakness and eventual mortality as a result of cardiomyopathy or respiratory complications are the hallmarks of Duchenne muscular dystrophy (DMD), a severe X-linked disorder. At present, there is no cure for DMD, and the primary focus of standard treatments is on symptom management. Gene therapies can more effectively address the genetic cause of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2192,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[66,33,72,61],"class_list":["post-2190","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-duchenne-muscular-dystrophy","tag-elevidys","tag-gene-editing","tag-gene-therapy"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2190","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=2190"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/2190\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/2192"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=2190"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=2190"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=2190"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}