{"id":1855,"date":"2024-12-12T14:23:56","date_gmt":"2024-12-12T11:23:56","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=1855"},"modified":"2024-12-12T14:26:49","modified_gmt":"2024-12-12T11:26:49","slug":"18-digit-code-wnt7a-that-allows-proteins-to-hitch-a-ride-around-the-body","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/zh\/18-digit-code-wnt7a-that-allows-proteins-to-hitch-a-ride-around-the-body\/","title":{"rendered":"\u7814\u7a76\u4eba\u5458\u53d1\u73b0 18 \u4f4d\u4ee3\u7801 (Wnt7a)\uff0c\u53ef\u8ba9\u86cb\u767d\u8d28\u5728\u4f53\u5185\u201c\u642d\u4fbf\u8f66\u201d"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>\u6e25\u592a\u534e\u5927\u5b66\u548c\u6e25\u592a\u534e\u533b\u9662\u7684\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4e86\u4e00\u4e2a 18 \u4f4d\u4ee3\u7801 (Wnt7a)\uff0c\u86cb\u767d\u8d28\u53ef\u4ee5\u5229\u7528\u5b83\u4e0e\u5916\u6ccc\u4f53\u7ed3\u5408\uff0c\u5916\u6ccc\u4f53\u662f\u7ec6\u80de\u7684\u5fae\u5c0f\u788e\u7247\uff0c\u53ef\u4ee5\u5728\u5168\u8eab\u79fb\u52a8\u5e76\u4f20\u9012\u751f\u5316\u4fe1\u606f\u3002<\/strong> \u8be5\u7814\u7a76\u7ed3\u679c\u53d1\u8868\u5728\u300a\u79d1\u5b66\u8fdb\u5c55\u300b\u6742\u5fd7\u4e0a\uff0c\u5bf9\u65b0\u5174\u7684\u5916\u6ccc\u4f53\u6cbb\u7597\u9886\u57df\u5177\u6709\u91cd\u8981\u5f71\u54cd\uff0c\u5916\u6ccc\u4f53\u6cbb\u7597\u65e8\u5728\u5229\u7528\u5916\u6ccc\u4f53\u8fd0\u8f93\u6cbb\u7597\u591a\u79cd\u75be\u75c5\u7684\u836f\u7269\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8be5\u7814\u7a76\u7684\u8d44\u6df1\u4f5c\u8005\u3001\u6e25\u592a\u534e\u533b\u9662\u518d\u751f\u533b\u5b66\u9879\u76ee\u4e3b\u4efb\u3001\u6e25\u592a\u534e\u5927\u5b66\u6559\u6388\u8fc8\u514b\u5c14\u00b7\u9c81\u5fb7\u5c3c\u8328\u57fa\u535a\u58eb\u8868\u793a\uff1a\u201c\u86cb\u767d\u8d28\u662f\u4eba\u4f53\u81ea\u5df1\u5236\u9020\u7684\u836f\u7269\uff0c\u4f46\u5b83\u4eec\u4e0d\u4e00\u5b9a\u80fd\u5728\u4f53\u5185\u5f88\u597d\u5730\u4f20\u64ad\u3002\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201c\u7531\u4e8e\u8fd9\u4e00\u53d1\u73b0\uff0c\u6211\u4eec\u73b0\u5728\u53ef\u4ee5\u4f7f\u7528\u5916\u6ccc\u4f53\u5c06\u4efb\u4f55\u86cb\u767d\u8d28\u8fd0\u8f93\u5230\u5168\u8eab\u3002 <strong>\u5b83\u4e3a\u836f\u7269\u5f00\u53d1\u7684\u5168\u65b0\u9886\u57df\u63d0\u4f9b\u4e86\u9014\u5f84\u3002<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Rudnicki \u535a\u58eb\u548c\u4ed6\u7684\u540c\u4e8b\u53d1\u73b0\uff0c\u4e00\u79cd\u540d\u4e3a Wnt7a \u7684\u86cb\u767d\u8d28\u542b\u6709\u4e00\u4e2a\u5916\u6ccc\u4f53\u9776\u5411\u90ae\u653f\u7f16\u7801\uff0c\u8fd9\u79cd\u86cb\u767d\u8d28\u5bf9\u53d1\u80b2\u3001\u751f\u957f\u3001\u518d\u751f\u548c\u764c\u75c7\u81f3\u5173\u91cd\u8981\u3002\u4ed6\u4eec\u9996\u5148\u8bc1\u660e\u4e86 Wnt7a \u80fd\u591f\u4e0e\u5916\u6ccc\u4f53\u7ed3\u5408\u3002\u63a5\u4e0b\u6765\uff0c\u4ed6\u4eec\u6d88\u9664\u4e86 Wnt7a \u86cb\u767d\u8d28\u7684\u51e0\u4e2a\u533a\u57df\uff0c\u76f4\u5230\u786e\u5b9a\u4e86\u8d1f\u8d23\u5916\u6ccc\u4f53\u9776\u5411\u7684\u6700\u77ed\u533a\u57df\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fd9\u79cd\u7531 18 \u4e2a\u6c28\u57fa\u9178\u7ec4\u6210\u7684\u6210\u5206\u88ab\u79f0\u4e3a\u5916\u6ccc\u4f53\u7ed3\u5408\u80bd (EBP)\u3002\u4ed6\u4eec\u968f\u540e\u53d1\u73b0\uff0cEBP \u53ef\u7528\u4e8e\u5c06\u4efb\u4f55\u86cb\u767d\u8d28\u9776\u5411\u5916\u6ccc\u4f53\uff0c\u5e76\u4e14\u5b83\u4e0e\u5916\u6ccc\u4f53\u4e0a\u79f0\u4e3a\u8863\u58f3\u86cb\u767d\u7684\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b2c\u4e00\u4f5c\u8005 Uxia Gurriaran-Rodriguez \u535a\u58eb\u66fe\u662f Michael Rudnicki \u535a\u58eb\u56e2\u961f\u7684\u535a\u58eb\u540e\u7814\u7a76\u5458\uff0c\u76ee\u524d\u53d7\u96c7\u4e8e\u897f\u73ed\u7259\u751f\u7269\u79d1\u5b66\u5408\u4f5c\u7814\u7a76\u4e2d\u5fc3 (CIC bioGUNE)\uff0c\u4ed6\u8868\u793a\uff1a\u201c\u591a\u5e74\u6765\uff0c\u7814\u7a76\u4eba\u5458\u4e00\u76f4\u5728\u5c1d\u8bd5\u5c06 Wnt7a \u8f6c\u5316\u4e3a\u808c\u8089\u518d\u751f\u836f\u7269\uff0c\u4f46\u5c06 Wnt7a \u8f93\u9001\u5230\u5168\u8eab\u975e\u5e38\u56f0\u96be\uff0c\u56e0\u4e3a\u5b83\u88ab\u8102\u80aa\u5206\u5b50\u8986\u76d6\uff0c\u4e0e\u4f53\u6db2\u4e0d\u6613\u6df7\u5408\u3002\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u201c\u73b0\u5728\u6211\u4eec\u77e5\u9053\u4e86Wnt7a\u5982\u4f55\u9644\u7740\u4e8e\u5916\u6ccc\u4f53\uff0c\u6211\u4eec\u5c31\u89e3\u51b3\u4e86\u8fd9\u4e2a\u95ee\u9898\uff0c\u73b0\u5728\u53ef\u4ee5\u52a0\u901f\u5f00\u53d1\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7b49\u6bc1\u706d\u6027\u75be\u75c5\u7684\u836f\u7269\u3002\u201d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u6765\u6e90\uff1a<\/strong> https:\/\/www.ohri.ca\/newsroom\/story\/view\/1742?l=en<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7814\u7a76\uff1a<\/strong> https:\/\/www.science.org\/doi\/10.1126\/sciadv.ado5914<\/p>","protected":false},"excerpt":{"rendered":"<p>Researchers from the University of Ottawa and The Ottawa Hospital have found an 18-digit code (Wnt7a) that proteins can use to bind to exosomes, which are tiny, pinched-off fragments of cells that move throughout the body and transmit biochemical information. The finding, which was reported in Science Advances, has significant ramifications for the emerging field [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1857,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[37,36,40,38,39,35],"class_list":["post-1855","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-exosome-therapy","tag-exosomes","tag-michael-rudnicki","tag-ottawa","tag-university-of-ottawa","tag-wnt7a"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/1855","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/comments?post=1855"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/posts\/1855\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media\/1857"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/media?parent=1855"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/categories?post=1855"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/zh\/wp-json\/wp\/v2\/tags?post=1855"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}