{"id":4740,"date":"2025-10-07T12:35:42","date_gmt":"2025-10-07T09:35:42","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=4740"},"modified":"2025-11-03T20:18:48","modified_gmt":"2025-11-03T17:18:48","slug":"new-data-presented-on-duvyzat-givinostat-for-treatment-of-duchenne-muscular-dystrophy-at-2025-world-muscle-society-congress","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/tr\/new-data-presented-on-duvyzat-givinostat-for-treatment-of-duchenne-muscular-dystrophy-at-2025-world-muscle-society-congress\/","title":{"rendered":"2025 D\u00fcnya Kas Derne\u011fi Kongresi&#039;nde Duchenne Musk\u00fcler Distrofi Tedavisinde Duvyzat (Givinostat) ile \u0130lgili Yeni Veriler Sunuldu"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>Italfarmaco, 7-11 Ekim tarihleri aras\u0131nda Avusturya&#039;n\u0131n Viyana kentinde d\u00fczenlenen 30. D\u00fcnya Kas Toplulu\u011fu (WMS) Uluslararas\u0131 Kongresi&#039;nde, Duchenne kas distrofisi (DMD) tedavisinde kullan\u0131lan givinostat ile ilgili ek verilerin sunulaca\u011f\u0131n\u0131 duyurdu.<\/strong> Poster sunumlar\u0131, DMD&#039;li hastalarda givinostat\u0131n uzun vadeli g\u00fcvenli\u011fini vurgulamakta, \u00f6nemli EPIDYS \u00e7al\u0131\u015fmas\u0131n\u0131n post-hoc analizinde ya\u015fa g\u00f6re etkinli\u011fini incelemekte ve bu Faz 3 \u00e7al\u0131\u015fmada g\u00f6zlemlenen gastrointestinal advers olaylar\u0131n ayr\u0131nt\u0131l\u0131 bir karakterizasyonunu sa\u011flamaktad\u0131r. <a href=\"https:\/\/dmdwarrior.com\/tr\/duvyzat-givinostat-nonsteroidal-drug\/\" target=\"_blank\" data-type=\"post\" data-id=\"3957\" rel=\"noreferrer noopener\">Duvyzat (Givinostat) Nedir?<\/a> &gt;&gt;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Italfarmaco taraf\u0131ndan desteklenen ve 2025 WMS Kongresi&#039;nde sunulan \u00e7al\u0131\u015fmalardan elde edilen veriler \u015funlard\u0131r:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>651P Duchenne Musk\u00fcler Distrofisi Olan Hastalarda Givinostat&#039;\u0131n Uzun D\u00f6nemli G\u00fcvenli\u011fi: A\u00e7\u0131k Etiketli Bir Uzatma \u00c7al\u0131\u015fmas\u0131ndan Elde Edilen Sonu\u00e7lar<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">DMD&#039;li erkek \u00e7ocuklarda givinostat \u00fczerine devam eden uzun s\u00fcreli \u00e7al\u0131\u015fma, tedavinin g\u00fcvenli\u011fi ve tolerabilitesi hakk\u0131nda daha \u00f6nceki k\u0131sa s\u00fcreli \u00e7al\u0131\u015fmalarla tutarl\u0131 sonu\u00e7lar sunarak, tedavinin g\u00fcvenilirli\u011fi ve tolere edilebilirli\u011fi konusunda fikir vermeye devam etmektedir. Baz\u0131 hastalar, \u00e7e\u015fitli \u00e7al\u0131\u015fmalar ve uzatma a\u015famalar\u0131 boyunca toplamda 8 y\u0131ldan uzun s\u00fcredir givinostat kullanmaktad\u0131r.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>684VP Givinostat&#039;\u0131n Ya\u015fa G\u00f6re Etkinli\u011fi (6-7 ve &gt;7 Ya\u015f): EPIDYS&#039;in Post Hoc Analizi<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u00c7al\u0131\u015fmada yap\u0131lan temel de\u011ferlendirmeler, farkl\u0131 ya\u015f gruplar\u0131ndaki DMD&#039;li erkek \u00e7ocuklar\u0131n fiziksel i\u015flevlerine ili\u015fkin \u00f6nemli bilgiler sa\u011flad\u0131.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>688VP Duchenne Musk\u00fcler Distrofisi Olan Hastalarda Givinostat&#039;\u0131n Faz 3 \u00c7al\u0131\u015fmas\u0131ndan Elde Edilen \u0130lgi \u00c7ekici Gastrointestinal Olumsuz Olaylar\u0131n Karakterizasyonu<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u00c7al\u0131\u015fma, kat\u0131l\u0131mc\u0131larda gastrointestinal olaylar\u0131 izlemeye devam etmekte olup, bildirilen olaylar\u0131n \u00e7o\u011fu hafif ila orta \u015fiddette olup, tedavinin kesilmesini gerektirmeden d\u00fczelmektedir. Bu bulgular, uzun s\u00fcreli tedavinin genel g\u00fcvenli\u011fini ve tolere edilebilirli\u011fini anlamak i\u00e7in \u00f6nemli bir ba\u011flam sa\u011flamaktad\u0131r.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Devam\u0131n\u0131 oku<\/strong>:\u00a0<a href=\"https:\/\/dmdwarrior.com\/tr\/dmd-therapies\/\" target=\"_blank\" rel=\"noreferrer noopener\">Duchenne \u0130\u00e7in Klinik Ara\u015ft\u0131rmalar (T\u00fcm Ara\u015ft\u0131rmalar\u0131n Listesi)<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Italfarmaco announced that additional data on givinostat for the treatment of Duchenne muscular dystrophy (DMD) are being presented at the 30th annual International Congress of the World Muscle Society (WMS) held October 7-11 in Vienna, Austria. Poster presentations highlight the long-term safety of givinostat in patients with DMD, explore efficacy by age in a post [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4741,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[46,47,311],"class_list":["post-4740","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-duvyzat","tag-givinostat","tag-italfarmaco"],"subtitle":"Italfarmaco, D\u00fcnya Kas Derne\u011fi'nin 30. Uluslararas\u0131 Kongresi'nde Duchenne kas distrofisi (DMD) i\u00e7in Duvyzat (Givinostat) ile ilgili yeni verileri sundu.","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/4740","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/comments?post=4740"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/4740\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media\/4741"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media?parent=4740"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/categories?post=4740"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/tags?post=4740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}