{"id":4192,"date":"2026-08-09T14:39:36","date_gmt":"2026-08-09T11:39:36","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=4192"},"modified":"2026-08-09T14:39:39","modified_gmt":"2026-08-09T11:39:39","slug":"mutations-and-deletions-amenable-to-exon-44-skipping-therapies-dmd","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/tr\/mutations-and-deletions-amenable-to-exon-44-skipping-therapies-dmd\/","title":{"rendered":"Duchenne Musk\u00fcler Distrofisi \u0130\u00e7in Ekzon 44 Atlama Terapilerine Uygun Mutasyonlar ve Delesyonlar"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>Ekzon 44 atlamaya uygun delesyonlar (silinmeler), DMD geninde ekzon 44'\u00fcn atlanmas\u0131n\u0131n okuma \u00e7er\u00e7evesini geri kazand\u0131rabilece\u011fi ve kas h\u00fccrelerinin daha k\u0131sa, potansiyel olarak i\u015flevsel bir distrofin proteini \u00fcretmesine olanak sa\u011flayabilece\u011fi spesifik genetik de\u011fi\u015fikliklerdir.<\/strong> Duchenne kas distrofisi (DMD) hastal\u0131\u011f\u0131ndan etkilenen aileler i\u00e7in, \u00e7ocu\u011fun sahip oldu\u011fu mutasyonun 44. ekzon atlamaya uygun delesyonlar aras\u0131nda olup olmad\u0131\u011f\u0131n\u0131 anlamak, ortaya \u00e7\u0131kan ekzon atlama terapilerini ve klinik \u00e7al\u0131\u015fmalar\u0131 de\u011ferlendirirken \u00f6nemli olabilir.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">DMD, distrofin \u00fcretimini sa\u011flayan DMD genindeki patojenik varyantlardan kaynaklan\u0131r. Bir\u00e7ok DMD delesyonu, genin okuma \u00e7er\u00e7evesini bozarak, i\u015flevsel distrofinin az veya hi\u00e7 olmamas\u0131na neden olur. Ekzon atlama, haberci RNA'dan ek bir ekzonun \u00e7\u0131kar\u0131lmas\u0131n\u0131 sa\u011flayarak, kalan dizinin tekrar \u00e7er\u00e7eve i\u00e7inde okunabilmesini ama\u00e7lar. <strong>Bu nedenle, ekzon 44'\u00fc hedef alan tedaviler klinik geli\u015ftirme a\u015famas\u0131nda ilerledik\u00e7e, ekzon 44 atlamas\u0131na uygun delesyonlar \u00fczerine yap\u0131lan ara\u015ft\u0131rmalar giderek daha \u00f6nemli hale gelmi\u015ftir.<\/strong> \u015eimdi \u00d6\u011frenin: <a href=\"https:\/\/dmdwarrior.com\/tr\/dystrophin-gene\/\" target=\"_blank\" rel=\"noreferrer noopener\">DMD geni nedir?<\/a><\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>\u0130\u00e7indekiler<\/h2><nav><ul><li><a href=\"#which-dmd-deletions-are-amenable-to-exon-44-skipping\">Hangi DMD Delesyonlar\u0131 44. Ekzon Atlamaya Uygundur?<\/a><\/li><li><a href=\"#why-does-skipping-exon-44-matter\">44. Ekzonun Atlanmas\u0131n\u0131n \u00d6nemi Nedir?<\/a><\/li><li><a href=\"#current-exon-44-skipping-clinical-trials\">G\u00fcncel Ekzon 44 Atlama Klinik \u00c7al\u0131\u015fmalar\u0131<\/a><\/li><li><a href=\"#how-can-a-family-determine-whether-a-dmd-mutation-is-amenable\">Bir aile, DMD mutasyonunun tedaviye uygun olup olmad\u0131\u011f\u0131n\u0131 nas\u0131l belirleyebilir?<\/a><\/li><li><a href=\"#exon-45-deletion-and-exon-44-skipping\">Ekzon 45 Silinmesi ve Ekzon 44 Atlanmas\u0131<\/a><\/li><li><a href=\"#academic-sources-and-references\">Akademik Kaynaklar ve Referanslar<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<h2 id=\"which-dmd-deletions-are-amenable-to-exon-44-skipping\" class=\"wp-block-heading\">Hangi DMD Delesyonlar\u0131 44. Ekzon Atlamaya Uygundur?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Bu referans i\u00e7in talep edilen ve 44. ekzonun atlanmas\u0131na uygun olan silme i\u015flemleri \u015funlard\u0131r:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Ekzon 44 Atlamas\u0131 \u0130\u00e7in DMD Silme Listesi: 10-43, 11-43, 13-43, 14-43, 15-43, 16-43, 17-43, 19-43, 21-43, 23-43, 24-43, 25-43, 26-43, 27-43, 28-43, 29-43, 30-43, 31-43, 32-43, 33-43, 34-43, 35-43, 36-43, 37-43, 38-43, 39-43, 40-43, 41-43, 42-43, 43, 45, 45-54, 45-56 ve 45-62.<\/strong><\/p>\n\n\n\n<div><a href=\"https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR.jpg\" class=\"td-modal-image\"><figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1890\" height=\"2000\" src=\"https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR.jpg\" alt=\"Duchenne Musk\u00fcler Distrofisi \u0130\u00e7in Ekzon 44 Atlama Terapilerine Uygun Mutasyonlar ve Delesyonlar\" class=\"wp-image-5275\" title=\"\" srcset=\"https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR.jpg 1890w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-284x300.jpg 284w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-968x1024.jpg 968w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-768x813.jpg 768w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-1452x1536.jpg 1452w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-11x12.jpg 11w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-397x420.jpg 397w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-150x159.jpg 150w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-300x317.jpg 300w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-696x737.jpg 696w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/12\/Deletions-Amenable-to-Exon-44-Skipping-TR-1068x1130.jpg 1068w\" sizes=\"(max-width: 1890px) 100vw, 1890px\" \/><\/figure><\/a><\/div>\n\n\n\n<h2 id=\"why-does-skipping-exon-44-matter\" class=\"wp-block-heading\">44. Ekzonun Atlanmas\u0131n\u0131n \u00d6nemi Nedir?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Ekzon 44 atlanmas\u0131na olanak sa\u011flayan silinmelerin temel prensibi, okuma \u00e7er\u00e7evesinin yeniden olu\u015fturulmas\u0131d\u0131r. <strong>E\u011fer bir delesyon, DMD geninin normal \u00fc\u00e7 bazl\u0131 okuma yap\u0131s\u0131n\u0131 bozarsa, ortaya \u00e7\u0131kan haberci RNA, ciddi \u015fekilde k\u0131salt\u0131lm\u0131\u015f veya hi\u00e7 bulunmayan bir distrofin proteini \u00fcretebilir.<\/strong> 44. ekzonun \u00e7\u0131kar\u0131lmas\u0131, orijinal silinmeyi telafi edebilir ve \u00e7er\u00e7eve i\u00e7i bir transkripti geri y\u00fckleyebilir.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Olu\u015fan distrofinin tam uzunlukta olmas\u0131 beklenmez. Bunun yerine, ekzon atlama y\u00f6ntemi, \u00f6nemli fonksiyonel b\u00f6lgeleri koruyan daha k\u0131sa bir distrofin \u00fcretmeyi ama\u00e7lar. Bu yakla\u015f\u0131m bazen Duchenne benzeri genetik bir kusuru daha hafif, Becker benzeri molek\u00fcler bir sonuca d\u00f6n\u00fc\u015ft\u00fcrme giri\u015fimi olarak tan\u0131mlan\u0131r. Bununla birlikte, klinik etki yaln\u0131zca delesyon s\u0131n\u0131rlar\u0131ndan tahmin edilemez. Daha Fazlas\u0131n\u0131 Okuyun: <a href=\"https:\/\/dmdwarrior.com\/tr\/what-is-exon-skipping-and-how-does-it-work\/\" target=\"_blank\" data-type=\"post\" data-id=\"1445\" rel=\"noreferrer noopener\">Ekzon Atlama Nedir?<\/a><\/p>\n\n\n\n<h2 id=\"current-exon-44-skipping-clinical-trials\" class=\"wp-block-heading\">G\u00fcncel Ekzon 44 Atlama Klinik \u00c7al\u0131\u015fmalar\u0131<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Ekzon 44 atlama terapisi geli\u015ftirme \u00e7al\u0131\u015fmalar\u0131 insan klinik \u00e7al\u0131\u015fmalar\u0131na kadar ilerlemi\u015ftir.<\/strong> Entrada Therapeutics' ENTR-601-44, ekzon 44 atlamas\u0131na uygun DMD'li kat\u0131l\u0131mc\u0131larda Faz 1\/2 ELEVATE-44 \u00e7al\u0131\u015fmas\u0131nda de\u011ferlendirilmektedir. ClinicalTrials.gov, \u00e7al\u0131\u015fmay\u0131 g\u00fcvenlik, tolere edilebilirlik, farmakokinetik, farmakodinamik ve etkinli\u011fi de\u011ferlendiren m\u00fcdahale edici bir Faz 1\/2 deneme olarak listelemektedir.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ekzon 44 atlamas\u0131na uygun DMD mutasyonlar\u0131na sahip kat\u0131l\u0131mc\u0131larda ba\u015fka bir ekzon 44 program\u0131 olan AOC 1044 de incelenmi\u015ftir. EXPLORE44 program\u0131, deneysel tedavinin g\u00fcvenli\u011fini, tolerans\u0131n\u0131, farmakokineti\u011fini ve farmakodinamik etkilerini de\u011ferlendirmi\u015ftir.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bu programlar, ekzon 44 atlamas\u0131na uygun delesyonlar hakk\u0131ndaki bilgilerin aileler i\u00e7in neden giderek daha \u00f6nemli hale geldi\u011fini g\u00f6stermektedir. Bununla birlikte, deneysel tedaviler onaylanm\u0131\u015f tedaviler olarak yorumlanmamal\u0131 ve klinik deneme uygunlu\u011fu her zaman resmi protokolden belirlenmelidir. Daha Fazla Bilgi Edinin: <a href=\"https:\/\/dmdwarrior.com\/clinical-trials\/active-studies\/\" target=\"_blank\" rel=\"noreferrer noopener\">Aktif DMD Klinik \u00c7al\u0131\u015fmalar\u0131<\/a><\/p>\n\n\n\n<h2 id=\"how-can-a-family-determine-whether-a-dmd-mutation-is-amenable\" class=\"wp-block-heading\">Bir aile, DMD mutasyonunun tedaviye uygun olup olmad\u0131\u011f\u0131n\u0131 nas\u0131l belirleyebilir?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0130lk ad\u0131m, \u00e7ocu\u011fun eksiksiz genetik raporunu edinmektir. &quot;42-43. ekzonun silinmesi&quot; gibi bir ifade nispeten basittir, ancak daha b\u00fcy\u00fck silinmeler, ekzon s\u0131n\u0131rlar\u0131n\u0131n dikkatli bir \u015fekilde yorumlanmas\u0131n\u0131 gerektirebilir. \u015eimdi Ke\u015ffedin: <a href=\"https:\/\/dmdwarrior.com\/tr\/duchenne-exon-deletion-tool\/\" target=\"_blank\" rel=\"noreferrer noopener\">DMD mi yoksa BMD mi? Ekzon Kontrol Arac\u0131<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Aileler, ekzon 44 atlanmas\u0131na uygun delesyonlar\u0131n \u00e7evrimi\u00e7i listesinde bulunan bir delesyonun ad\u0131na tek ba\u015f\u0131na g\u00fcvenmemelidir.<\/strong> N\u00f6rom\u00fcsk\u00fcler hastal\u0131klar uzman\u0131, molek\u00fcler genetik\u00e7i veya genetik dan\u0131\u015fman, s\u00f6z konusu varyant\u0131 incelemeli ve 44. ekzon atlamas\u0131n\u0131n okuma \u00e7er\u00e7evesini geri kazand\u0131r\u0131p kazand\u0131rmayaca\u011f\u0131n\u0131 belirlemelidir.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Genetik yatk\u0131nl\u0131\u011f\u0131 tedaviye eri\u015fimden ay\u0131rt etmek de \u00f6nemlidir. Bir mutasyon teorik olarak ekzon 44 atlamas\u0131na yan\u0131t verebilirken, belirli bir \u00fclkede onaylanm\u0131\u015f ekzon 44 atlama ilac\u0131 bulunmayabilir. Benzer \u015fekilde, bir klinik \u00e7al\u0131\u015fman\u0131n mutasyonun kendisiyle ilgisi olmayan ek gereksinimleri olabilir.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Daha fazla bilgi edin<\/strong>: <a href=\"https:\/\/dmdwarrior.com\/tr\/upcoming-exon-44-skipping-therapies-for-dmd\/\">Duchenne Tedavisinde Yakla\u015fan Ekzon 44 Atlama Terapileri<\/a><\/p>\n\n\n\n<h2 id=\"exon-45-deletion-and-exon-44-skipping\" class=\"wp-block-heading\">Ekzon 45 Silinmesi ve Ekzon 44 Atlanmas\u0131<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Ekzon 44'\u00fcn atlanmas\u0131na uygun en \u00f6nemli delesyonlar aras\u0131nda ekzon 45'in delesyonu yer almaktad\u0131r.<\/strong> Ekzon 45 delesyonu, iyi bilinen bir ekzon 44 atlama genotipidir ve do\u011fal tarih ve molek\u00fcler \u00e7al\u0131\u015fmalarda \u00f6nemli ilgi g\u00f6rm\u00fc\u015ft\u00fcr.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ara\u015ft\u0131rmac\u0131lar, ekzon 45 delesyonu olan baz\u0131 bireylerde endojen ekzon 44 atlamas\u0131 g\u00f6r\u00fcld\u00fc\u011f\u00fcn\u00fc ve terap\u00f6tik m\u00fcdahale olmaks\u0131z\u0131n \u00e7er\u00e7eve i\u00e7i bir transkript \u00fcretildi\u011fini bildirmi\u015flerdir. Duchenne Kay\u0131t Defteri'ndeki \u00e7al\u0131\u015fmalar ayr\u0131ca, \u00f6zellikle ekzon 45 delesyonu olan ki\u015filerde, ekzon 44 atlamas\u0131na yatk\u0131n mutasyonlar\u0131n, di\u011fer \u00e7e\u015fitli DMD mutasyon gruplar\u0131na k\u0131yasla y\u00fcr\u00fcme yetene\u011fini kaybetme ya\u015f\u0131 a\u00e7\u0131s\u0131ndan farkl\u0131l\u0131klar g\u00f6sterdi\u011fini ortaya koymu\u015ftur.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bu g\u00f6zlem, ekzon 45 delesyonunun hafif bir durum oldu\u011fu veya spontan ekzon atlamas\u0131n\u0131n yeterli distrofin sa\u011flad\u0131\u011f\u0131 anlam\u0131na gelmez. Aksine, alternatif eklemenin fenotipi nas\u0131l etkileyebilece\u011fini g\u00f6stermekte ve ekzon 44'\u00fc terap\u00f6tik olarak hedeflemeye y\u00f6nelik biyolojik destek sa\u011flamaktad\u0131r.<\/p>\n\n\n\n<h2 id=\"academic-sources-and-references\" class=\"wp-block-heading\">Akademik Kaynaklar ve Referanslar<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Van den Bergen JC, Ginjaar HB, Niks EH, Aartsma-Rus A, Verschuuren JJGM. Ekzon 44 Atlamaya Uygun Mutasyona Sahip Duchenne Hastalar\u0131nda Uzun S\u00fcre Ambulasyon. <a href=\"https:\/\/journals.sagepub.com\/doi\/10.3233\/JND-140002\" target=\"_blank\" rel=\"noopener\">N\u00f6rom\u00fcsk\u00fcler Hastal\u0131klar Dergisi<\/a>. 2014;1(1):91\u201394.<\/li>\n\n\n\n<li>Dwianingsih EK, Malueka RG, Nishida A, Itoh K, Lee T, Yagi M, Iijima K, Takeshima Y, Matsuo M. DMD ekzon 45 delesyon birle\u015fimi taraf\u0131ndan olu\u015fturulan yeni bir ekleme susturucusu, distrofinopatiyi de\u011fi\u015ftiren yukar\u0131 ak\u0131\u015f ekzon 44 atlamas\u0131n\u0131 a\u00e7\u0131klayabilir. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24871807\/\" target=\"_blank\" rel=\"noopener\">\u0130nsan Geneti\u011fi Dergisi<\/a>. 2014;59:423\u2013429.<\/li>\n\n\n\n<li>Lu QL, Cirak S, Partridge T. DMD i\u00e7in Ekzon Atlama Y\u00f6nteminin Klinik Denemelerinden Neler \u00d6\u011frenebiliriz? <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4027981\/\" target=\"_blank\" rel=\"noreferrer noopener\">N\u00f6rom\u00fcsk\u00fcler Hastal\u0131klar Dergisi. 2014<\/a>. Bu \u00e7al\u0131\u015fma, ekzon atlama stratejileri ve bunlar\u0131n DMD'de distrofin ekspresyonunu geri kazand\u0131rma potansiyeli hakk\u0131nda \u00f6nemli bir ba\u011flam sa\u011flamaktad\u0131r.<\/li>\n\n\n\n<li>Lim KRQ, Maruyama R, Yokota T. Duchenne kas distrofisi i\u00e7in antisens oligon\u00fckleotid arac\u0131l\u0131 ekzon atlama y\u00f6nteminin etkinli\u011fi ve s\u0131n\u0131rlamalar\u0131. Uluslararas\u0131 Molek\u00fcler Bilimler Dergisi. 2017. Bu derleme, ekzon atlama yakla\u015f\u0131mlar\u0131n\u0131n molek\u00fcler temellerini, terap\u00f6tik potansiyelini ve s\u0131n\u0131rlamalar\u0131n\u0131 ele almaktad\u0131r.<\/li>\n\n\n\n<li>Brogna C ve ark. 44, 45, 51 ve 53. ekzonlar\u0131n atlanmas\u0131na uygun, ayakta tedavi g\u00f6ren Duchenne hastas\u0131 \u00e7ocuklarda North Star Ambulatuvar De\u011ferlendirme de\u011fi\u015fiklikleri: 3 y\u0131ll\u0131k takip. N\u00f6rom\u00fcsk\u00fcler Bozukluklar. 2021. \u00c7al\u0131\u015fma, 44. ekzonun atlanmas\u0131na uygun delesyonlar\u0131 olan 34 hastay\u0131 i\u00e7ermekte olup, bu spesifik genetik alt grup i\u00e7in yararl\u0131 do\u011fal seyir verileri sa\u011flamaktad\u0131r.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>","protected":false},"excerpt":{"rendered":"<p>Deletions amenable to exon 44 skipping are specific genetic changes in the DMD gene for which skipping exon 44 may restore the reading frame and allow muscle cells to produce a shorter, potentially functional dystrophin protein. For families affected by Duchenne muscular dystrophy (DMD), understanding whether a child&#8217;s particular mutation is among the deletions amenable [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":8356,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[141,127,246,77,178],"class_list":["post-4192","post","type-post","status-publish","format-standard","has-post-thumbnail","category-dmd","tag-exon-44","tag-exon-44-skipping","tag-exon-44-skipping-therapies","tag-exon-skipping","tag-exon-skipping-therapies"],"subtitle":"O\u011flum ekzon 44 atlama tedavisi i\u00e7in uygun mu? Duchenne Musk\u00fcler Distrofisi'nde (DMD) ekzon 44 atlamaya uygun delesyonlar (silinmeler), hedefli ekzon atlama yakla\u015f\u0131mlar\u0131ndan fayda g\u00f6rebilecek hastalar\u0131 belirlemeye yard\u0131mc\u0131 olabilir. Hangi DMD delesyonlar\u0131n\u0131n uygun olabilece\u011fini, ekzon 44 atlaman\u0131n nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131n\u0131 ve ailelerin yeni tedaviler hakk\u0131nda bilmesi gerekenleri \u00f6\u011frenin.","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/4192","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/comments?post=4192"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/4192\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media\/8356"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media?parent=4192"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/categories?post=4192"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/tags?post=4192"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}