{"id":3823,"date":"2025-05-07T15:43:13","date_gmt":"2025-05-07T12:43:13","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=3823"},"modified":"2025-05-07T15:43:14","modified_gmt":"2025-05-07T12:43:14","slug":"sonothera-ultrasound-mediated-delivery-method-can-deliver-full-length-dystrophin-to-cells","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/tr\/sonothera-ultrasound-mediated-delivery-method-can-deliver-full-length-dystrophin-to-cells\/","title":{"rendered":"SonoThera Ultrason Arac\u0131l\u0131 Da\u011f\u0131t\u0131m Y\u00f6ntemi H\u00fccrelere Tam Uzunlukta Distrofin Sa\u011flayabilir"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u015eu anda Duchenne Musk\u00fcler Distrofi (DMD) tedavisi i\u00e7in SonoThera&#039;nin geli\u015ftirilmesi a\u015famas\u0131nda olan \u00e7al\u0131\u015fman\u0131n bulgular\u0131, Ultrason Arac\u0131l\u0131 \u0130la\u00e7 Da\u011f\u0131t\u0131m teknolojisinin genetik ila\u00e7lar\u0131 da\u011f\u0131tma yetene\u011fini g\u00f6stermektedir. <strong>Bu teknoloji, fare ve insan olmayan primat (NHP) modellerinde iskelet, kalp ve diyafram kaslar\u0131nda tam uzunlukta distrofin protein ekspresyonunu m\u00fcmk\u00fcn k\u0131l\u0131yor.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Yeni nesil genetik ila\u00e7lar geli\u015ftirerek insan hastal\u0131klar\u0131n\u0131n temel nedenini tedavi etmeye adanm\u0131\u015f bir biyoteknoloji \u015firketi olan SonoThera, bug\u00fcn 13-17 May\u0131s tarihleri aras\u0131nda New Orleans, Louisiana&#039;da d\u00fczenlenecek 28. Amerikan Gen ve H\u00fccre Terapisi Derne\u011fi (ASGCT) y\u0131ll\u0131k toplant\u0131s\u0131nda yeni veriler sunaca\u011f\u0131n\u0131 duyurdu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SonoThera CEO&#039;su Dr. Kenneth Greenberg, &quot;Genetik t\u0131ptaki temel zorluklar\u0131n \u00e7\u00f6z\u00fcm\u00fcnde ultrason arac\u0131l\u0131 iletim potansiyelini vurgulayan yeni verileri ASGCT&#039;de sunmaktan mutluluk duyuyoruz&quot; dedi. <strong>&quot;Bu veriler, kaslarda hedeflenen tam uzunlukta insan distrofin ekspresyonu ve dayan\u0131kl\u0131, g\u00fcvenli, tekrarlanabilir ve invaziv olmayan bir \u015fekilde b\u00fcy\u00fck boyutlu genetik y\u00fckler sa\u011flama dahil olmak \u00fczere benzersiz yeteneklerimizi g\u00f6stermeye devam ediyor.<\/strong> Bu y\u0131lki y\u0131ll\u0131k toplant\u0131da en son verilerimizi payla\u015fmay\u0131 sab\u0131rs\u0131zl\u0131kla bekliyoruz.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Daha fazla bilgi edin: <a href=\"https:\/\/dmdwarrior.com\/tr\/sonothera-presents-new-data-of-genetic-medicine-using-targeted-ultrasound-mediated-delivery-umd-in-treating-duchenne-muscular-dystrophy\/\" target=\"_blank\" rel=\"noreferrer noopener\">Ultrason Arac\u0131l\u0131 \u0130letim (UMD)<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>The findings of the study, which are currently being developed for SonoThera&#8217;s Duchenne Muscular Dystrophy (DMD) treatment, demonstrate the capability of Ultrasound-Mediated Delivery technology to deliver genetic drugs. This technology enables full-length dystrophin protein expression in skeletal, cardiac, and diaphragm muscles in mouse and non-human primate (NHP) models. SonoThera, a biotechnology company dedicated to treating [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3824,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[366,359,367,285,286],"class_list":["post-3823","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-asgct-2025","tag-full-length-dystrophin","tag-kenneth-greenberg","tag-sonothera","tag-ultrasound-mediated-delivery"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/3823","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/comments?post=3823"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/3823\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media\/3824"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media?parent=3823"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/categories?post=3823"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/tags?post=3823"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}