{"id":3823,"date":"2025-05-07T15:43:13","date_gmt":"2025-05-07T12:43:13","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=3823"},"modified":"2025-05-07T15:43:14","modified_gmt":"2025-05-07T12:43:14","slug":"sonothera-ultrasound-mediated-delivery-method-can-deliver-full-length-dystrophin-to-cells","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/tr\/sonothera-ultrasound-mediated-delivery-method-can-deliver-full-length-dystrophin-to-cells\/","title":{"rendered":"SonoThera Ultrason Arac\u0131l\u0131 Da\u011f\u0131t\u0131m Y\u00f6ntemi H\u00fccrelere Tam Uzunlukta Distrofin Sa\u011flayabilir"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u015eu anda Duchenne Musk\u00fcler Distrofi (DMD) tedavisi i\u00e7in SonoThera&#039;nin geli\u015ftirilmesi a\u015famas\u0131nda olan \u00e7al\u0131\u015fman\u0131n bulgular\u0131, Ultrason Arac\u0131l\u0131 \u0130la\u00e7 Da\u011f\u0131t\u0131m teknolojisinin genetik ila\u00e7lar\u0131 da\u011f\u0131tma yetene\u011fini g\u00f6stermektedir. <strong>Bu teknoloji, fare ve insan olmayan primat (NHP) modellerinde iskelet, kalp ve diyafram kaslar\u0131nda tam uzunlukta distrofin protein ekspresyonunu m\u00fcmk\u00fcn k\u0131l\u0131yor.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Yeni nesil genetik ila\u00e7lar geli\u015ftirerek insan hastal\u0131klar\u0131n\u0131n temel nedenini tedavi etmeye adanm\u0131\u015f bir biyoteknoloji \u015firketi olan SonoThera, bug\u00fcn 13-17 May\u0131s tarihleri aras\u0131nda New Orleans, Louisiana&#039;da d\u00fczenlenecek 28. Amerikan Gen ve H\u00fccre Terapisi Derne\u011fi (ASGCT) y\u0131ll\u0131k toplant\u0131s\u0131nda yeni veriler sunaca\u011f\u0131n\u0131 duyurdu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SonoThera CEO&#039;su Dr. Kenneth Greenberg, &quot;Genetik t\u0131ptaki temel zorluklar\u0131n \u00e7\u00f6z\u00fcm\u00fcnde ultrason arac\u0131l\u0131 iletim potansiyelini vurgulayan yeni verileri ASGCT&#039;de sunmaktan mutluluk duyuyoruz&quot; dedi. <strong>&quot;Bu veriler, kaslarda hedeflenen tam uzunlukta insan distrofin ekspresyonu ve dayan\u0131kl\u0131, g\u00fcvenli, tekrarlanabilir ve invaziv olmayan bir \u015fekilde b\u00fcy\u00fck boyutlu genetik y\u00fckler sa\u011flama dahil olmak \u00fczere benzersiz yeteneklerimizi g\u00f6stermeye devam ediyor.<\/strong> Bu y\u0131lki y\u0131ll\u0131k toplant\u0131da en son verilerimizi payla\u015fmay\u0131 sab\u0131rs\u0131zl\u0131kla bekliyoruz.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Daha fazla bilgi edin: <a href=\"https:\/\/dmdwarrior.com\/tr\/sonothera-presents-new-data-of-genetic-medicine-using-targeted-ultrasound-mediated-delivery-umd-in-treating-duchenne-muscular-dystrophy\/\" target=\"_blank\" rel=\"noreferrer noopener\">Ultrason Arac\u0131l\u0131 \u0130letim (UMD)<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>The findings of the study, which are currently being developed for SonoThera&#8217;s Duchenne Muscular Dystrophy (DMD) treatment, demonstrate the capability of Ultrasound-Mediated Delivery technology to deliver genetic drugs. This technology enables full-length dystrophin protein expression in skeletal, cardiac, and diaphragm muscles in mouse and non-human primate (NHP) models. SonoThera, a biotechnology company dedicated to treating [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3824,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[366,359,367,285,286],"class_list":["post-3823","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-asgct-2025","tag-full-length-dystrophin","tag-kenneth-greenberg","tag-sonothera","tag-ultrasound-mediated-delivery"],"subtitle":"\u015eu anda SonoThera'nin DMD tedavisi i\u00e7in geli\u015ftirilme a\u015famas\u0131nda olan \u00e7al\u0131\u015fmadan elde edilen veriler, Ultrason Arac\u0131l\u0131 Da\u011f\u0131t\u0131m teknolojisinin genetik ila\u00e7lar\u0131 iletme yetene\u011fini g\u00f6stererek, fare ve insan olmayan primat (NHP) modellerinde iskelet, kalp ve diyafram kaslar\u0131nda tam uzunlukta distrofin protein ekspresyonuna izin verdi\u011fini g\u00f6stermektedir.","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/3823","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/comments?post=3823"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/3823\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media\/3824"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media?parent=3823"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/categories?post=3823"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/tags?post=3823"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}