{"id":2438,"date":"2025-01-15T12:28:10","date_gmt":"2025-01-15T09:28:10","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2438"},"modified":"2025-01-15T12:28:12","modified_gmt":"2025-01-15T09:28:12","slug":"the-fda-designates-ips-hearts-givi-mpc-stem-cell-therapy-for-becker-muscular-dystrophy-an-orphan-drug","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/tr\/the-fda-designates-ips-hearts-givi-mpc-stem-cell-therapy-for-becker-muscular-dystrophy-an-orphan-drug\/","title":{"rendered":"FDA, IPS HEART&#039;\u0131n Becker Musk\u00fcler Distrofisi i\u00e7in GIVI-MPC K\u00f6k H\u00fccre Terapisini Yetim \u0130la\u00e7 Olarak Belirledi"},"content":{"rendered":"<p class=\"wp-block-paragraph\">FDA, Becker Musk\u00fcler Distrofisi (BMD) hastalar\u0131nda tam uzunlukta distrofin ile yeni kas \u00fcretme konusundaki ola\u011fan\u00fcst\u00fc kapasitesi nedeniyle GIVI-MPC&#039;ler i\u00e7in IPS HEART Yetim \u0130la\u00e7 Tan\u0131m\u0131 (ODD) almaya hak kazand\u0131.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">IPS HEART taraf\u0131ndan GIVI-MPC&#039;lerin sarkopeni, gen\u00e7 ve \u00e7ok ya\u015fl\u0131 Duchenne Musk\u00fcler Distrofi (DMD) fareleri ve distrofik domuzlardan olu\u015fan bir fare modelinde tam uzunlukta insan distrofinli yeni insan kas\u0131 \u00fcretti\u011fi g\u00f6sterilmi\u015ftir. GIVI-MPC&#039;lerin zay\u0131flat\u0131c\u0131 hastal\u0131klar\u0131 tersine \u00e7evirmek i\u00e7in ola\u011fan\u00fcst\u00fc platform potansiyelini g\u00f6stermek amac\u0131yla, FDA daha \u00f6nce GIVI-MPC&#039;lere DMD i\u00e7in Yetim \u0130la\u00e7 Tan\u0131m\u0131 vermi\u015ftir.<\/p>","protected":false},"excerpt":{"rendered":"<p>The FDA has granted IPS HEART Orphan Drug Designation (ODD) for GIVI-MPCs because of its exceptional capacity to produce new muscle with full length dystrophin in patients with Becker Muscular Dystrophy (BMD). It has now been demonstrated by IPS HEART that GIVI-MPCs produce new human muscle with full length human dystrophin in a mouse model [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2441,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[67,73,88,160,161],"class_list":["post-2438","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-becker-muscular-dystrophy","tag-dystrophin","tag-fda","tag-givi-mpc","tag-ips-heart"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/2438","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/comments?post=2438"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/posts\/2438\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media\/2441"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/media?parent=2438"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/categories?post=2438"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/tr\/wp-json\/wp\/v2\/tags?post=2438"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}