{"id":5295,"date":"2025-12-08T16:05:39","date_gmt":"2025-12-08T13:05:39","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=5295"},"modified":"2025-12-08T16:08:05","modified_gmt":"2025-12-08T13:08:05","slug":"dyne-therapeutics-to-apply-for-accelerated-approval-in-q2-2026-for-exon-51-skipping-therapy-dyne-251-z-rostudirsen","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ru\/dyne-therapeutics-to-apply-for-accelerated-approval-in-q2-2026-for-exon-51-skipping-therapy-dyne-251-z-rostudirsen\/","title":{"rendered":"Dyne Therapeutics \u043f\u043e\u0434\u0430\u0441\u0442 \u0437\u0430\u044f\u0432\u043a\u0443 \u043d\u0430 \u0443\u0441\u043a\u043e\u0440\u0435\u043d\u043d\u043e\u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d\u0438\u0435 \u0432\u043e \u0432\u0442\u043e\u0440\u043e\u043c \u043a\u0432\u0430\u0440\u0442\u0430\u043b\u0435 2026 \u0433\u043e\u0434\u0430 \u0434\u043b\u044f \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u043f\u0440\u043e\u043f\u0443\u0441\u043a\u0430 \u044d\u043a\u0437\u043e\u043d\u0430 51 (DYNE-251)"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u041a\u043e\u043c\u043f\u0430\u043d\u0438\u044f Dyne Therapeutics \u043e\u0431\u044a\u044f\u0432\u0438\u043b\u0430 \u043e \u043f\u043e\u043b\u043e\u0436\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u043e\u0441\u043d\u043e\u0432\u043d\u044b\u0445 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0430\u0445, \u043f\u043e\u043b\u0443\u0447\u0435\u043d\u043d\u044b\u0445 \u0432 \u0445\u043e\u0434\u0435 \u043a\u043e\u0433\u043e\u0440\u0442\u044b \u0440\u0430\u0441\u0448\u0438\u0440\u0435\u043d\u0438\u044f \u0440\u0435\u0433\u0438\u0441\u0442\u0440\u0430\u0446\u0438\u0438 (REC) \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u0444\u0430\u0437\u044b 1\/2 DELIVER \u043f\u043e \u043e\u0446\u0435\u043d\u043a\u0435 \u0446\u0435\u043b\u0435\u0446\u0438\u043c\u0435\u043d\u0442\u0430 \u0440\u043e\u0441\u0442\u0443\u0434\u0438\u0440\u0441\u0435\u043d\u0430 (z-\u0440\u043e\u0441\u0442\u0443\u0434\u0438\u0440\u0441\u0435\u043d\u0430, \u0442\u0430\u043a\u0436\u0435 \u0438\u0437\u0432\u0435\u0441\u0442\u043d\u043e\u0433\u043e \u043a\u0430\u043a DYNE-251) \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0435\u0439 \u0414\u044e\u0448\u0435\u043d\u043d\u0430 (\u041c\u0414\u0414), \u043f\u043e\u0434\u0434\u0430\u044e\u0449\u0438\u0445\u0441\u044f \u043f\u0440\u043e\u043f\u0443\u0441\u043a\u0443 \u044d\u043a\u0437\u043e\u043d\u0430 51.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0423\u0437\u043d\u0430\u0439\u0442\u0435 \u0441\u0435\u0439\u0447\u0430\u0441:<\/strong> <a href=\"https:\/\/dmdwarrior.com\/ru\/mutations-and-deletions-amenable-to-exon-51-skipping-therapies-dmd\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u041c\u0443\u0442\u0430\u0446\u0438\u0438 \u0438 \u0434\u0435\u043b\u0435\u0446\u0438\u0438, \u043f\u043e\u0434\u0434\u0430\u044e\u0449\u0438\u0435\u0441\u044f \u0442\u0435\u0440\u0430\u043f\u0438\u0438, \u043f\u0440\u043e\u043f\u0443\u0441\u043a\u0430\u044e\u0449\u0435\u0439 \u044d\u043a\u0437\u043e\u043d 51<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u0420\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f DYNE-251<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u041a\u043e\u0433\u043e\u0440\u0442\u0430 \u0440\u0430\u0441\u0448\u0438\u0440\u0435\u043d\u0438\u044f \u0440\u0435\u0433\u0438\u0441\u0442\u0440\u0430\u0446\u0438\u0438 (REC) \u0434\u043e\u0441\u0442\u0438\u0433\u043b\u0430 \u043f\u0435\u0440\u0432\u0438\u0447\u043d\u043e\u0439 \u043a\u043e\u043d\u0435\u0447\u043d\u043e\u0439 \u0442\u043e\u0447\u043a\u0438, \u043f\u0440\u043e\u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u043e\u0432\u0430\u0432 \u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u043e\u0435 \u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u043d\u0430 \u0434\u043e 5,46% \u0447\u0435\u0440\u0435\u0437 6 \u043c\u0435\u0441\u044f\u0446\u0435\u0432 (\u0441 \u043f\u043e\u043f\u0440\u0430\u0432\u043a\u043e\u0439 \u043d\u0430 \u0441\u043e\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u0435 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u043c\u0430\u0441\u0441\u044b; p &lt; 0,0001), \u043f\u043e\u0432\u0442\u043e\u0440\u0438\u0432 \u0442\u043e \u0436\u0435 7-\u043a\u0440\u0430\u0442\u043d\u043e\u0435 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u0435 \u043f\u043e \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u044e \u0441 \u0438\u0441\u0445\u043e\u0434\u043d\u044b\u043c \u0443\u0440\u043e\u0432\u043d\u0435\u043c, \u043a\u043e\u0442\u043e\u0440\u043e\u0435 \u0440\u0430\u043d\u0435\u0435 \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u043b\u043e\u0441\u044c \u043f\u0440\u0438 \u0440\u0435\u0433\u0438\u0441\u0442\u0440\u0430\u0446\u0438\u043e\u043d\u043d\u043e\u0439 \u0434\u043e\u0437\u0435 \u2013<\/li>\n\n\n\n<li><strong>\u0424\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0435 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u0435 \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u043b\u043e\u0441\u044c \u043f\u043e \u043d\u0435\u0441\u043a\u043e\u043b\u044c\u043a\u0438\u043c \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u043c \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044f\u043c \u0432 \u0442\u0435\u0447\u0435\u043d\u0438\u0435 6 \u043c\u0435\u0441\u044f\u0446\u0435\u0432 \u0432 REC; \u0444\u0443\u043d\u043a\u0446\u0438\u044f \u043b\u0435\u0433\u043a\u0438\u0445 \u0441\u043e\u0445\u0440\u0430\u043d\u044f\u043b\u0430\u0441\u044c \u0432 \u0442\u0435\u0447\u0435\u043d\u0438\u0435 6 \u043c\u0435\u0441\u044f\u0446\u0435\u0432 \u2013<\/strong><\/li>\n\n\n\n<li>\u041d\u043e\u0432\u044b\u0435 \u043f\u043e\u043b\u043e\u0436\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0435 \u0434\u043e\u043b\u0433\u043e\u0441\u0440\u043e\u0447\u043d\u044b\u0435 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f DELIVER \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u0438 \u0443\u0441\u0442\u043e\u0439\u0447\u0438\u0432\u043e\u0435 \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0435 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u0435 \u043f\u043e \u0432\u0441\u0435\u043c \u043e\u0446\u0435\u043d\u0438\u0432\u0430\u0435\u043c\u044b\u043c \u043a\u043e\u043d\u0435\u0447\u043d\u044b\u043c \u0442\u043e\u0447\u043a\u0430\u043c \u0432 \u0442\u0435\u0447\u0435\u043d\u0438\u0435 24 \u043c\u0435\u0441\u044f\u0446\u0435\u0432 \u2013<\/li>\n\n\n\n<li><strong>\u041f\u0440\u043e\u0434\u043e\u043b\u0436\u0430\u044e\u0449\u0438\u0439\u0441\u044f \u0431\u043b\u0430\u0433\u043e\u043f\u0440\u0438\u044f\u0442\u043d\u044b\u0439 \u043f\u0440\u043e\u0444\u0438\u043b\u044c \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u0438 \u0438 \u043f\u0435\u0440\u0435\u043d\u043e\u0441\u0438\u043c\u043e\u0441\u0442\u0438 \u2013<\/strong><\/li>\n\n\n\n<li>\u041f\u043e\u0434\u0430\u0447\u0430 \u0437\u0430\u044f\u0432\u043a\u0438 \u043d\u0430 \u0443\u0441\u043a\u043e\u0440\u0435\u043d\u043d\u043e\u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d\u0438\u0435 \u0432 \u0421\u0428\u0410 \u0437\u0430\u043f\u043b\u0430\u043d\u0438\u0440\u043e\u0432\u0430\u043d\u0430 \u043d\u0430 \u0432\u0442\u043e\u0440\u043e\u0439 \u043a\u0432\u0430\u0440\u0442\u0430\u043b 2026 \u0433\u043e\u0434\u0430.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u041f\u043e\u0434\u043f\u0438\u0441\u0430\u0442\u044c\u0441\u044f \u043d\u0430 \u044d\u0442\u0443 \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0443<\/strong>&nbsp;&gt;&gt;&gt;&nbsp;<a href=\"https:\/\/dmdwarrior.com\/ru\/dmd-therapies\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0412\u0441\u0435 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0438\u0441\u043f\u044b\u0442\u0430\u043d\u0438\u044f \u043f\u043e \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Dyne Therapeutics announced positive topline results from the Registrational Expansion Cohort (REC) of its Phase 1\/2 DELIVER trial evaluating zeleciment rostudirsen (z-rostudirsen, also known as DYNE-251) in individuals with Duchenne muscular dystrophy (DMD) amenable to exon 51 skipping. Discover Now: Mutations and Deletions Amenable to Exon 51 Skipping Therapies Results of DYNE-251 Clinical Trial Follow [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":5297,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[143,208,145,122,193,421,194,460],"class_list":["post-5295","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-dyne","tag-dyne-therapeutics","tag-dyne-251","tag-exon-51","tag-exon-51-skipping","tag-exon-51-skipping-therapy","tag-exon-51-treatment","tag-z-rostudirsen"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/5295","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/comments?post=5295"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/5295\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media\/5297"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media?parent=5295"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/categories?post=5295"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/tags?post=5295"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}