{"id":5285,"date":"2025-12-03T17:41:43","date_gmt":"2025-12-03T14:41:43","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=5285"},"modified":"2025-12-03T17:52:01","modified_gmt":"2025-12-03T14:52:01","slug":"capricor-therapeutics-announces-positive-topline-results","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ru\/capricor-therapeutics-announces-positive-topline-results\/","title":{"rendered":"Capricor Therapeutics \u043e\u0431\u044a\u044f\u0432\u043b\u044f\u0435\u0442 \u043e \u043f\u043e\u043b\u043e\u0436\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u043e\u0441\u043d\u043e\u0432\u043d\u044b\u0445 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0430\u0445 \u043a\u043b\u044e\u0447\u0435\u0432\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u0444\u0430\u0437\u044b 3 HOPE-3 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0430 Deramiocel \u043f\u0440\u0438 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430"},"content":{"rendered":"

HOPE-3 \u2014 \u044d\u0442\u043e \u0440\u0430\u043d\u0434\u043e\u043c\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u043e\u0435 \u0434\u0432\u043e\u0439\u043d\u043e\u0435 \u0441\u043b\u0435\u043f\u043e\u0435 \u043f\u043b\u0430\u0446\u0435\u0431\u043e-\u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0438\u0440\u0443\u0435\u043c\u043e\u0435 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 III \u0444\u0430\u0437\u044b, \u043e\u0446\u0435\u043d\u0438\u0432\u0430\u044e\u0449\u0435\u0435 \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0430 Deramiocel \u0443 \u043c\u0430\u043b\u044c\u0447\u0438\u043a\u043e\u0432 \u0438 \u043c\u043e\u043b\u043e\u0434\u044b\u0445 \u043c\u0443\u0436\u0447\u0438\u043d \u0441 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0435\u0439 \u0414\u044e\u0448\u0435\u043d\u043d\u0430. \u0412 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0438 \u0443\u0447\u0430\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 106 \u0447\u0435\u043b\u043e\u0432\u0435\u043a, \u0440\u0430\u043d\u0434\u043e\u043c\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0445 \u0432 20 \u0432\u0435\u0434\u0443\u0449\u0438\u0445 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0446\u0435\u043d\u0442\u0440\u0430\u0445 \u0421\u0428\u0410. \u0423\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u0438 \u043f\u043e\u043b\u0443\u0447\u0430\u043b\u0438 Deramiocel \u0432\u043d\u0443\u0442\u0440\u0438\u0432\u0435\u043d\u043d\u043e \u0432 \u0434\u043e\u0437\u0435 150 \u043c\u0438\u043b\u043b\u0438\u043e\u043d\u043e\u0432 \u043a\u043b\u0435\u0442\u043e\u043a \u043d\u0430 \u0438\u043d\u0444\u0443\u0437\u0438\u044e \u0438\u043b\u0438 \u043f\u043b\u0430\u0446\u0435\u0431\u043e \u043a\u0430\u0436\u0434\u044b\u0435 \u0442\u0440\u0438 \u043c\u0435\u0441\u044f\u0446\u0430 \u0432 \u0442\u0435\u0447\u0435\u043d\u0438\u0435 12 \u043c\u0435\u0441\u044f\u0446\u0435\u0432.<\/p>\n\n\n\n

\u0421\u0440\u0435\u0434\u043d\u0438\u0439 \u0432\u043e\u0437\u0440\u0430\u0441\u0442 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u043e\u0432 \u0441\u043e\u0441\u0442\u0430\u0432\u0438\u043b \u043e\u043a\u043e\u043b\u043e 15 \u043b\u0435\u0442, \u0438 \u0432\u0441\u0435 \u043e\u043d\u0438 \u043d\u0430\u0445\u043e\u0434\u0438\u043b\u0438\u0441\u044c \u043d\u0430 \u0441\u0442\u0430\u0431\u0438\u043b\u044c\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u043a\u043e\u0440\u0442\u0438\u043a\u043e\u0441\u0442\u0435\u0440\u043e\u0438\u0434\u0430\u043c\u0438 \u043d\u0430 \u043f\u0440\u043e\u0442\u044f\u0436\u0435\u043d\u0438\u0438 \u0432\u0441\u0435\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f. \u0418\u0441\u0445\u043e\u0434\u043d\u044b\u0435 \u0434\u0435\u043c\u043e\u0433\u0440\u0430\u0444\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0434\u0430\u043d\u043d\u044b\u0435 \u0431\u044b\u043b\u0438 \u0445\u043e\u0440\u043e\u0448\u043e \u0441\u0431\u0430\u043b\u0430\u043d\u0441\u0438\u0440\u043e\u0432\u0430\u043d\u044b \u043c\u0435\u0436\u0434\u0443 \u0433\u0440\u0443\u043f\u043f\u0430\u043c\u0438 \u043b\u0435\u0447\u0435\u043d\u0438\u044f: \u043f\u0440\u0438\u043c\u0435\u0440\u043d\u043e 90% \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u043d\u0430 \u043c\u043e\u043c\u0435\u043d\u0442 \u043d\u0430\u0447\u0430\u043b\u0430 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u043f\u0440\u0438\u043d\u0438\u043c\u0430\u043b\u0438 \u043a\u0430\u0440\u0434\u0438\u043e\u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u044b, \u0430 \u0431\u043e\u043b\u0435\u0435 75% \u0438\u043c\u0435\u043b\u0438 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u0443\u044e \u043a\u0430\u0440\u0434\u0438\u043e\u043c\u0438\u043e\u043f\u0430\u0442\u0438\u044e. Deramiocel \u0441\u043e\u0445\u0440\u0430\u043d\u044f\u043b \u0431\u043b\u0430\u0433\u043e\u043f\u0440\u0438\u044f\u0442\u043d\u044b\u0439 \u043f\u0440\u043e\u0444\u0438\u043b\u044c \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u0438 \u0438 \u043f\u0435\u0440\u0435\u043d\u043e\u0441\u0438\u043c\u043e\u0441\u0442\u0438, \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0443\u044e\u0449\u0438\u0439 \u043f\u0440\u0435\u0434\u044b\u0434\u0443\u0449\u0435\u043c\u0443 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u043c\u0443 \u043e\u043f\u044b\u0442\u0443. >>>\u00a0\u0427\u0442\u043e \u0442\u0430\u043a\u043e\u0435 Deramiocel? \u0427\u0442\u043e \u0434\u0435\u043b\u0430\u0435\u0442 CAP-1002?<\/a><\/p>\n\n\n\n

\u0420\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u043c\u0430\u043a\u0441\u0438\u043c\u0430\u043b\u044c\u043d\u043e\u0439 \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438<\/h2>\n\n\n\n
\u041a\u043e\u043d\u0435\u0447\u043d\u0430\u044f \u0442\u043e\u0447\u043a\u0430<\/strong><\/td>% \u0417\u0430\u043c\u0435\u0434\u043b\u0435\u043d\u0438\u0435 \u043f\u0440\u043e\u0433\u0440\u0435\u0441\u0441\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f<\/strong>3<\/strong><\/sup>
(Deramiocel \u043f\u0440\u043e\u0442\u0438\u0432 \u043f\u043b\u0430\u0446\u0435\u0431\u043e)<\/strong><\/td>		p-\u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435<\/strong><\/td><\/tr>
\u041e\u0431\u0449\u0430\u044f \u043e\u0446\u0435\u043d\u043a\u0430 \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u0432\u0435\u0440\u0445\u043d\u0438\u0445 \u043a\u043e\u043d\u0435\u0447\u043d\u043e\u0441\u0442\u0435\u0439 (PUL v2.0)<\/strong>\u00b9
(\u041f\u0435\u0440\u0432\u0438\u0447\u043d\u043e\u0435, n=105)<\/td>		54%<\/td>\u0440=0,029<\/td><\/tr>
\u0424\u0440\u0430\u043a\u0446\u0438\u044f \u0432\u044b\u0431\u0440\u043e\u0441\u0430 \u043b\u0435\u0432\u043e\u0433\u043e \u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043a\u0430 (LVEF %)<\/strong>\u00b2
(\u041a\u043b\u044e\u0447\u0435\u0432\u043e\u0439 \u0432\u0442\u043e\u0440\u0438\u0447\u043d\u044b\u0439, n=83)<\/td>		91%<\/td>\u0440=0,041<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u00b9 n \u043e\u0442\u0440\u0430\u0436\u0430\u0435\u0442 \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u043e \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0432 \u043f\u043e\u043f\u0443\u043b\u044f\u0446\u0438\u0438 ITT \u0441 \u043e\u0446\u0435\u043d\u043a\u043e\u0439 PUL v2.0 \u0447\u0435\u0440\u0435\u0437 12 \u043c\u0435\u0441\u044f\u0446\u0435\u0432.
\u00b2 n \u043e\u0442\u0440\u0430\u0436\u0430\u0435\u0442 \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u043e \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0432 \u043f\u043e\u043f\u0443\u043b\u044f\u0446\u0438\u0438 ITT, \u0443 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u041c\u0420\u0422 \u0441\u0435\u0440\u0434\u0446\u0430 \u0438 \u0424\u0412\u041b\u0416 \u0431\u044b\u043b\u0438 \u0446\u0435\u043d\u0442\u0440\u0430\u043b\u0438\u0437\u043e\u0432\u0430\u043d\u043d\u043e \u043f\u0440\u043e\u0432\u0435\u0440\u0435\u043d\u044b \u0438 \u043e\u0446\u0435\u043d\u0435\u043d\u044b \u0447\u0435\u0440\u0435\u0437 12 \u043c\u0435\u0441\u044f\u0446\u0435\u0432.
3 <\/sup>\u041f\u0440\u043e\u0446\u0435\u043d\u0442 \u0437\u0430\u043c\u0435\u0434\u043b\u0435\u043d\u0438\u044f \u0440\u0430\u0441\u0441\u0447\u0438\u0442\u044b\u0432\u0430\u0435\u0442\u0441\u044f \u043a\u0430\u043a \u0440\u0430\u0437\u043d\u0438\u0446\u0430 \u0432 \u043b\u0435\u0447\u0435\u043d\u0438\u0438, \u0434\u0435\u043b\u0435\u043d\u043d\u0430\u044f \u043d\u0430 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u0435 \u0432 \u043f\u0440\u0438\u0435\u043c\u0435 \u043f\u043b\u0430\u0446\u0435\u0431\u043e \u043f\u043e \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u044e \u0441 \u0438\u0441\u0445\u043e\u0434\u043d\u044b\u043c \u0443\u0440\u043e\u0432\u043d\u0435\u043c.<\/p>\n\n\n\n

\u041f\u043e\u0434\u043f\u0438\u0441\u0430\u0442\u044c\u0441\u044f \u043d\u0430 \u044d\u0442\u0443 \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0443<\/strong> >>> \u0412\u0441\u0435 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0438\u0441\u043f\u044b\u0442\u0430\u043d\u0438\u044f \u043f\u043e \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430<\/a><\/p>","protected":false},"excerpt":{"rendered":"

HOPE-3 is a randomized, double-blind, placebo-controlled, Phase 3 clinical trial evaluating Deramiocel in boys and young men with Duchenne muscular dystrophy. The study randomized 106 participants across 20 leading U.S. clinical sites. Participants received intravenous Deramiocel at 150 million cells per infusion or placebo every three months for a 12-month period. The average age of […]<\/p>\n","protected":false},"author":1,"featured_media":5287,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[86,87,303,137,85],"class_list":["post-5285","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-capricor","tag-capricor-therapeutics","tag-cell-therapy","tag-clinical-trial","tag-deramiocel"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/5285","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/comments?post=5285"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/5285\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media\/5287"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media?parent=5285"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/categories?post=5285"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/tags?post=5285"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}