{"id":4274,"date":"2025-08-04T17:03:02","date_gmt":"2025-08-04T14:03:02","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=4274"},"modified":"2025-08-04T17:13:24","modified_gmt":"2025-08-04T14:13:24","slug":"dyne-therapeutics-announces-fda-breakthrough-therapy-designation-for-dyne-251-in-duchenne-muscular-dystrophy-dmd","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ru\/dyne-therapeutics-announces-fda-breakthrough-therapy-designation-for-dyne-251-in-duchenne-muscular-dystrophy-dmd\/","title":{"rendered":"Dyne Therapeutics \u043e\u0431\u044a\u044f\u0432\u043b\u044f\u0435\u0442 \u043e \u043f\u0440\u0438\u0441\u0432\u043e\u0435\u043d\u0438\u0438 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0443 FDA \u0441\u0442\u0430\u0442\u0443\u0441\u0430 \u043f\u0440\u0438\u043d\u0446\u0438\u043f\u0438\u0430\u043b\u044c\u043d\u043e \u043d\u043e\u0432\u043e\u0433\u043e \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0430 \u0434\u043b\u044f \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430 (\u041c\u0414\u0414)"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u041a\u043e\u043c\u043f\u0430\u043d\u0438\u044f Dyne Therapeutics \u043e\u0431\u044a\u044f\u0432\u0438\u043b\u0430 \u043e \u0442\u043e\u043c, \u0447\u0442\u043e \u0423\u043f\u0440\u0430\u0432\u043b\u0435\u043d\u0438\u0435 \u043f\u043e \u0441\u0430\u043d\u0438\u0442\u0430\u0440\u043d\u043e\u043c\u0443 \u043d\u0430\u0434\u0437\u043e\u0440\u0443 \u0437\u0430 \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u043e\u043c \u043f\u0438\u0449\u0435\u0432\u044b\u0445 \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u043e\u0432 \u0438 \u043c\u0435\u0434\u0438\u043a\u0430\u043c\u0435\u043d\u0442\u043e\u0432 \u0421\u0428\u0410 (FDA) \u043f\u0440\u0438\u0441\u0432\u043e\u0438\u043b\u043e \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0443 DYNE-251 \u0441\u0442\u0430\u0442\u0443\u0441 \u00ab\u043f\u0440\u043e\u0440\u044b\u0432\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438\u00bb \u0434\u043b\u044f \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0435\u0439 \u0414\u044e\u0448\u0435\u043d\u043d\u0430 (\u041c\u0414\u0414), \u043f\u043e\u0434\u0434\u0430\u044e\u0449\u0435\u0439\u0441\u044f \u043b\u0435\u0447\u0435\u043d\u0438\u044e \u043c\u0435\u0442\u043e\u0434\u043e\u043c \u043f\u0440\u043e\u043f\u0443\u0441\u043a\u0430 \u044d\u043a\u0437\u043e\u043d\u0430 51. \u041f\u0440\u0438\u0441\u0432\u043e\u0435\u043d\u0438\u0435 \u0441\u0442\u0430\u0442\u0443\u0441\u0430 \u043e\u0441\u043d\u043e\u0432\u0430\u043d\u043e \u043d\u0430 \u0434\u0430\u043d\u043d\u044b\u0445 \u0442\u0435\u043a\u0443\u0449\u0435\u0433\u043e \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f DELIVER.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">DYNE-251: \u041e\u0431\u043e\u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435 \u043f\u0440\u043e\u0440\u044b\u0432\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u00ab\u041f\u0440\u0438\u0441\u0432\u043e\u0435\u043d\u0438\u0435 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0443 DYNE-251 \u0441\u0442\u0430\u0442\u0443\u0441\u0430 \u043f\u0440\u043e\u0440\u044b\u0432\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u0441\u0432\u0438\u0434\u0435\u0442\u0435\u043b\u044c\u0441\u0442\u0432\u0443\u0435\u0442 \u043e \u0435\u0433\u043e \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b\u0435 \u043a\u0430\u043a \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u043d\u043e\u0432\u043e\u0433\u043e \u043f\u043e\u043a\u043e\u043b\u0435\u043d\u0438\u044f, \u0440\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u0430\u043d\u043d\u043e\u0439 \u0434\u043b\u044f \u0434\u043e\u0441\u0442\u0438\u0436\u0435\u043d\u0438\u044f \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0433\u043e \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u044f \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u041c\u0414\u0414, \u0443 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u043f\u0440\u043e\u043f\u0443\u0441\u043a \u044d\u043a\u0437\u043e\u043d\u0430 51 \u043c\u043e\u0436\u0435\u0442 \u043f\u0440\u0438\u0432\u0435\u0441\u0442\u0438 \u043a \u0432\u044b\u0440\u0430\u0431\u043e\u0442\u043a\u0435 \u043f\u0440\u0430\u043a\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u043f\u043e\u043b\u043d\u043e\u0440\u0430\u0437\u043c\u0435\u0440\u043d\u043e\u0433\u043e \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u043d\u0430\u00bb, \u2014 \u0437\u0430\u044f\u0432\u0438\u043b \u0414\u0443\u0433 \u041a\u0435\u0440\u0440, \u0434\u043e\u043a\u0442\u043e\u0440 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u043d\u0430\u0443\u043a, \u0434\u043e\u043a\u0442\u043e\u0440 \u0444\u0438\u043b\u043e\u0441\u043e\u0444\u0438\u0438, \u0433\u043b\u0430\u0432\u043d\u044b\u0439 \u0432\u0440\u0430\u0447 \u043a\u043e\u043c\u043f\u0430\u043d\u0438\u0438 Dyne. \u00ab\u041a\u0430\u043a \u043c\u044b \u0443\u0436\u0435 \u0441\u043e\u043e\u0431\u0449\u0430\u043b\u0438 \u0440\u0430\u043d\u0435\u0435, \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442 DYNE-251 \u043f\u0440\u043e\u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u043e\u0432\u0430\u043b \u0443\u0441\u0442\u043e\u0439\u0447\u0438\u0432\u043e\u0435 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u0435 \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f \u0432 \u0442\u0435\u0447\u0435\u043d\u0438\u0435 \u0432\u043e\u0441\u0435\u043c\u043d\u0430\u0434\u0446\u0430\u0442\u0438 \u043c\u0435\u0441\u044f\u0446\u0435\u0432, \u043e\u0446\u0435\u043d\u0438\u0432\u0430\u0435\u043c\u043e\u0435 \u043f\u043e \u0442\u0430\u043a\u0438\u043c \u043a\u043b\u044e\u0447\u0435\u0432\u044b\u043c \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044f\u043c, \u043a\u0430\u043a \u0432\u0440\u0435\u043c\u044f \u043f\u043e\u0434\u044a\u0435\u043c\u0430 \u0438 \u0441\u043a\u043e\u0440\u043e\u0441\u0442\u044c \u0448\u0430\u0433\u0430 (95-\u0439 \u043f\u0440\u043e\u0446\u0435\u043d\u0442\u0438\u043b\u044c). \u041d\u0430\u0431\u043b\u044e\u0434\u0430\u0435\u043c\u044b\u0439 \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u044d\u043a\u0441\u043f\u0440\u0435\u0441\u0441\u0438\u0438 \u043f\u0440\u0430\u043a\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u043f\u043e\u043b\u043d\u043e\u0440\u0430\u0437\u043c\u0435\u0440\u043d\u043e\u0433\u043e \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u043d\u0430 \u0437\u043d\u0430\u043c\u0435\u043d\u0443\u0435\u0442 \u0441\u043e\u0431\u043e\u0439 \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0439 \u0448\u0430\u0433 \u0432\u043f\u0435\u0440\u0435\u0434 \u043a \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b\u044c\u043d\u043e \u0437\u043d\u0430\u0447\u0438\u043c\u043e\u043c\u0443 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u044e \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432\u00bb.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0423\u0437\u043d\u0430\u0442\u044c \u0431\u043e\u043b\u044c\u0448\u0435<\/strong>: <a href=\"https:\/\/dmdwarrior.com\/ru\/exon-51-skipping-therapies-dmd\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u041f\u0440\u0435\u0434\u0441\u0442\u043e\u044f\u0449\u0438\u0435 \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u043f\u0440\u043e\u043f\u0443\u0441\u043a\u0430 \u044d\u043a\u0437\u043e\u043d\u0430 51 \u0434\u043b\u044f \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0427\u0438\u0442\u0430\u0442\u044c \u0434\u0430\u043b\u0435\u0435<\/strong>: <a href=\"https:\/\/dmdwarrior.com\/ru\/dyne-therapeutics-receives-european-medicines-agency-ema-orphan-drug-designation-for-dyne-251-in-duchenne-muscular-dystrophy\/\">Dyne Therapeutics \u043f\u043e\u043b\u0443\u0447\u0438\u043b \u0441\u0442\u0430\u0442\u0443\u0441 \u043e\u0440\u0444\u0430\u043d\u043d\u043e\u0433\u043e \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0430 \u043e\u0442 \u0415\u0432\u0440\u043e\u043f\u0435\u0439\u0441\u043a\u043e\u0433\u043e \u0430\u0433\u0435\u043d\u0442\u0441\u0442\u0432\u0430 \u043f\u043e \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u043c \u0441\u0440\u0435\u0434\u0441\u0442\u0432\u0430\u043c (EMA) \u0434\u043b\u044f DYNE-251 \u043f\u0440\u0438 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Dyne Therapeutics announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation to DYNE-251 for the treatment of patients with Duchenne muscular dystrophy (DMD), amenable to exon 51 skipping. The designation is based on data from the ongoing DELIVER clinical trial. DYNE-251: Breakthrough Therapy Designation \u201cThis Breakthrough Therapy Designation for DYNE-251 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4275,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[208,145,122,193,194,88],"class_list":["post-4274","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-dyne-therapeutics","tag-dyne-251","tag-exon-51","tag-exon-51-skipping","tag-exon-51-treatment","tag-fda"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/4274","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/comments?post=4274"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/4274\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media\/4275"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media?parent=4274"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/categories?post=4274"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/tags?post=4274"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}