{"id":4013,"date":"2025-06-27T12:29:23","date_gmt":"2025-06-27T09:29:23","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=4013"},"modified":"2025-06-27T12:29:24","modified_gmt":"2025-06-27T09:29:24","slug":"entrada-therapeutics-begins-clinical-trials-in-europe-for-exon-44-and-exon-45-skipping-therapies","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ru\/entrada-therapeutics-begins-clinical-trials-in-europe-for-exon-44-and-exon-45-skipping-therapies\/","title":{"rendered":"Entrada Therapeutics \u043d\u0430\u0447\u0438\u043d\u0430\u0435\u0442 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0438\u0441\u043f\u044b\u0442\u0430\u043d\u0438\u044f \u0432 \u0415\u0432\u0440\u043e\u043f\u0435 \u0434\u043b\u044f \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u043f\u0440\u043e\u043f\u0443\u0441\u043a\u0430 \u044d\u043a\u0437\u043e\u043d\u0430 44 \u0438 \u044d\u043a\u0437\u043e\u043d\u0430 45"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u041a\u043e\u043c\u043f\u0430\u043d\u0438\u044f Entrada Therapeutics \u043e\u0444\u0438\u0446\u0438\u0430\u043b\u044c\u043d\u043e \u043d\u0430\u0447\u0430\u043b\u0430 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0438\u0441\u043f\u044b\u0442\u0430\u043d\u0438\u044f \u0432 \u0415\u0432\u0440\u043e\u043f\u0435 \u0441\u0432\u043e\u0435\u0439 \u0438\u043d\u043d\u043e\u0432\u0430\u0446\u0438\u043e\u043d\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u043f\u0440\u043e\u043f\u0443\u0441\u043a\u0430 \u044d\u043a\u0437\u043e\u043d\u043e\u0432, \u043d\u0430\u0446\u0435\u043b\u0435\u043d\u043d\u043e\u0439 \u043d\u0430 \u044d\u043a\u0437\u043e\u043d 44 \u0438 \u044d\u043a\u0437\u043e\u043d 45, \u0447\u0442\u043e \u0441\u0442\u0430\u043b\u043e \u0432\u0430\u0436\u043d\u043e\u0439 \u0432\u0435\u0445\u043e\u0439 \u0432 \u043b\u0435\u0447\u0435\u043d\u0438\u0438 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430 (\u041c\u0414\u0414).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u042d\u0442\u0438 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u0438\u0435 \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u043f\u0440\u0435\u0434\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d\u044b \u0434\u043b\u044f \u0443\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u0438\u044f \u0441\u043f\u0435\u0446\u0438\u0444\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043c\u0443\u0442\u0430\u0446\u0438\u0439 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u041c\u0414\u0414 \u0441 \u0446\u0435\u043b\u044c\u044e \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u044f \u0432\u044b\u0440\u0430\u0431\u043e\u0442\u043a\u0438 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u043d\u0430 \u0438 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u044f \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432. \u041d\u0430\u0447\u0430\u043b\u043e \u044d\u0442\u0438\u0445 \u0438\u0441\u043f\u044b\u0442\u0430\u043d\u0438\u0439 \u043f\u043e\u0434\u0447\u0435\u0440\u043a\u0438\u0432\u0430\u0435\u0442 \u043f\u0440\u0438\u0432\u0435\u0440\u0436\u0435\u043d\u043d\u043e\u0441\u0442\u044c Entrada \u043f\u0440\u043e\u0434\u0432\u0438\u0436\u0435\u043d\u0438\u044e \u0442\u043e\u0447\u043d\u043e\u0439 \u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u044b \u0438 \u0440\u0430\u0441\u0448\u0438\u0440\u0435\u043d\u0438\u044e \u0433\u043b\u043e\u0431\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0434\u043e\u0441\u0442\u0443\u043f\u0430 \u043a \u043d\u043e\u0432\u044b\u043c \u043c\u0435\u0442\u043e\u0434\u0430\u043c \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u0440\u0435\u0434\u043a\u0438\u0445 \u043d\u0435\u0440\u0432\u043d\u043e-\u043c\u044b\u0448\u0435\u0447\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439. \u2013 \u041f\u043e\u0434\u0440\u043e\u0431\u043d\u0435\u0435: <a href=\"https:\/\/dmdwarrior.com\/ru\/what-is-exon-skipping-and-how-does-it-work\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0427\u0442\u043e \u0442\u0430\u043a\u043e\u0435 \u043f\u0440\u043e\u043f\u0443\u0441\u043a \u044d\u043a\u0437\u043e\u043d\u043e\u0432 \u0438 \u043a\u0430\u043a \u043e\u043d \u0440\u0430\u0431\u043e\u0442\u0430\u0435\u0442?<\/a> \u2013<\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>\u041e\u0433\u043b\u0430\u0432\u043b\u0435\u043d\u0438\u0435<\/h2><nav><ul><li><a href=\"#entrada-exon-44-skipping-nct-07037862\">Entrada \u041f\u0440\u043e\u043f\u0443\u0441\u043a \u044d\u043a\u0437\u043e\u043d\u0430 44 \u2013 NCT07037862 \u2013<\/a><\/li><li><a href=\"#entrada-exon-45-skipping-nct-07038824\">Entrada \u041f\u0440\u043e\u043f\u0443\u0441\u043a \u044d\u043a\u0437\u043e\u043d\u0430 45 \u2013 NCT07038824 \u2013<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"entrada-exon-44-skipping-nct-07037862\">Entrada \u041f\u0440\u043e\u043f\u0443\u0441\u043a \u044d\u043a\u0437\u043e\u043d\u0430 44 \u2013 NCT07037862 \u2013<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u042d\u0442\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u044d\u043a\u0441\u043f\u0435\u0440\u0438\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0430 ENTR-601-44 \u0441 \u0443\u0447\u0430\u0441\u0442\u0438\u0435\u043c \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u043e\u0432, \u0441\u0442\u0440\u0430\u0434\u0430\u044e\u0449\u0438\u0445 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0435\u0439 \u0414\u044e\u0448\u0435\u043d\u043d\u0430 (\u041c\u0414\u0414) \u2014 \u0440\u0435\u0434\u043a\u0438\u043c \u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u043c \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0435\u043c.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u041d\u0430\u0447\u0430\u043b\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f (\u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u0435\u043c\u043e\u0435)<\/strong>: 2025-06-30<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u041f\u0435\u0440\u0432\u0438\u0447\u043d\u043e\u0435 \u0437\u0430\u0432\u0435\u0440\u0448\u0435\u043d\u0438\u0435 (\u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u0435\u043c\u043e\u0435)<\/strong>: 2029-03-28<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0417\u0430\u0432\u0435\u0440\u0448\u0435\u043d\u0438\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f (\u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u0435\u043c\u043e\u0435)<\/strong>: 2029-03-28<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u041a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u043e \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u043e\u0432 (\u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u0435\u043c\u043e\u0435)<\/strong>: 24<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u041c\u0435\u0441\u0442\u0430<\/strong>: \u0411\u0435\u043b\u044c\u0433\u0438\u044f, \u0418\u0442\u0430\u043b\u0438\u044f, \u0418\u0441\u043f\u0430\u043d\u0438\u044f, \u0412\u0435\u043b\u0438\u043a\u043e\u0431\u0440\u0438\u0442\u0430\u043d\u0438\u044f.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0412\u043e\u0437\u0440\u0430\u0441\u0442, \u043f\u043e\u0434\u0445\u043e\u0434\u044f\u0449\u0438\u0439 \u0434\u043b\u044f \u043e\u0431\u0443\u0447\u0435\u043d\u0438\u044f<\/strong>: \u043e\u0442 4 \u0434\u043e 20 \u043b\u0435\u0442 (\u0440\u0435\u0431\u0435\u043d\u043e\u043a, \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0439)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u041e\u0441\u043d\u043e\u0432\u043d\u044b\u0435 \u043a\u0440\u0438\u0442\u0435\u0440\u0438\u0438 \u0432\u043a\u043b\u044e\u0447\u0435\u043d\u0438\u044f \u0438 \u0438\u0441\u043a\u043b\u044e\u0447\u0435\u043d\u0438\u044f. \u2013 <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT07037862\" target=\"_blank\" rel=\"noreferrer noopener\">NCT07037862<\/a> \u2013<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"entrada-exon-45-skipping-nct-07038824\">Entrada \u041f\u0440\u043e\u043f\u0443\u0441\u043a \u044d\u043a\u0437\u043e\u043d\u0430 45 \u2013 NCT07038824 \u2013<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u042d\u0442\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u044d\u043a\u0441\u043f\u0435\u0440\u0438\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0430 ENTR-601-45 \u0441 \u0443\u0447\u0430\u0441\u0442\u0438\u0435\u043c \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u043e\u0432, \u0441\u0442\u0440\u0430\u0434\u0430\u044e\u0449\u0438\u0445 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0435\u0439 \u0414\u044e\u0448\u0435\u043d\u043d\u0430 (\u041c\u0414\u0414) \u2014 \u0440\u0435\u0434\u043a\u0438\u043c \u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u043c \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0435\u043c.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u041d\u0430\u0447\u0430\u043b\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f (\u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u0435\u043c\u043e\u0435)<\/strong>: 2025-09-30<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u041f\u0435\u0440\u0432\u0438\u0447\u043d\u043e\u0435 \u0437\u0430\u0432\u0435\u0440\u0448\u0435\u043d\u0438\u0435 (\u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u0435\u043c\u043e\u0435)<\/strong>: 2029-03-01<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0417\u0430\u0432\u0435\u0440\u0448\u0435\u043d\u0438\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f (\u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u0435\u043c\u043e\u0435)<\/strong>: 2029-03-01<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u041a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u043e \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u043e\u0432 (\u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u0435\u043c\u043e\u0435)<\/strong>: 24<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u041c\u0435\u0441\u0442\u0430<\/strong>: \u0411\u0435\u043b\u044c\u0433\u0438\u044f, \u0418\u0442\u0430\u043b\u0438\u044f, \u041d\u0438\u0434\u0435\u0440\u043b\u0430\u043d\u0434\u044b, \u0418\u0441\u043f\u0430\u043d\u0438\u044f, \u0412\u0435\u043b\u0438\u043a\u043e\u0431\u0440\u0438\u0442\u0430\u043d\u0438\u044f.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0412\u043e\u0437\u0440\u0430\u0441\u0442, \u043f\u043e\u0434\u0445\u043e\u0434\u044f\u0449\u0438\u0439 \u0434\u043b\u044f \u043e\u0431\u0443\u0447\u0435\u043d\u0438\u044f<\/strong>: \u043e\u0442 4 \u0434\u043e 20 \u043b\u0435\u0442 (\u0440\u0435\u0431\u0435\u043d\u043e\u043a, \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0439)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u041e\u0441\u043d\u043e\u0432\u043d\u044b\u0435 \u043a\u0440\u0438\u0442\u0435\u0440\u0438\u0438 \u0432\u043a\u043b\u044e\u0447\u0435\u043d\u0438\u044f \u0438 \u0438\u0441\u043a\u043b\u044e\u0447\u0435\u043d\u0438\u044f. \u2013 <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT07038824\" target=\"_blank\" rel=\"noreferrer noopener\">NCT07038824<\/a> \u2013<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/dmdwarrior.com\/ru\/tag\/entrada-therapeutics\/\">\u041f\u043e\u0434\u0440\u043e\u0431\u043d\u0435\u0435 \u043e Entrada Therapeutics<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>Entrada Therapeutics has officially launched clinical trials in Europe for its innovative exon skipping therapies targeting Exon 44 and Exon 45\u2014marking a significant milestone in the treatment of Duchenne muscular dystrophy (DMD). These investigational therapies are designed to address specific genetic mutations in DMD patients, with the goal of restoring dystrophin production and improving clinical [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4021,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[242,233,234,84,246,319,178],"class_list":["post-4013","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-clinical-trials","tag-entrada","tag-entrada-therapeutics","tag-europe","tag-exon-44-skipping-therapies","tag-exon-45-skipping-therapy","tag-exon-skipping-therapies"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/4013","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/comments?post=4013"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/4013\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media\/4021"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media?parent=4013"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/categories?post=4013"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/tags?post=4013"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}