{"id":2355,"date":"2025-01-08T17:41:32","date_gmt":"2025-01-08T14:41:32","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2355"},"modified":"2025-03-07T15:26:36","modified_gmt":"2025-03-07T12:26:36","slug":"avidity-biosciences-prepares-for-three-rare-muscle-disease-programs-2025-bla-submission-and-commercialization","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ru\/avidity-biosciences-prepares-for-three-rare-muscle-disease-programs-2025-bla-submission-and-commercialization\/","title":{"rendered":"Avidity Biosciences \u0433\u043e\u0442\u043e\u0432\u0438\u0442\u0441\u044f \u043a \u043f\u043e\u0434\u0430\u0447\u0435 \u0437\u0430\u044f\u0432\u043e\u043a \u043d\u0430 BLA \u0438 \u043a\u043e\u043c\u043c\u0435\u0440\u0446\u0438\u0430\u043b\u0438\u0437\u0430\u0446\u0438\u0438 \u0442\u0440\u0435\u0445 \u043f\u0440\u043e\u0433\u0440\u0430\u043c\u043c \u043f\u043e \u0440\u0435\u0434\u043a\u0438\u043c \u043c\u044b\u0448\u0435\u0447\u043d\u044b\u043c \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u043c \u0432 2025 \u0433\u043e\u0434\u0443"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u0411\u0438\u043e\u0444\u0430\u0440\u043c\u0430\u0446\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0444\u0438\u0440\u043c\u0430 Avidity Biosciences, Inc., \u0437\u0430\u043d\u0438\u043c\u0430\u044e\u0449\u0430\u044f\u0441\u044f \u0440\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u043a\u043e\u0439 \u043d\u043e\u0432\u043e\u0433\u043e \u043a\u043b\u0430\u0441\u0441\u0430 \u0420\u041d\u041a-\u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u043e\u0432, \u0438\u0437\u0432\u0435\u0441\u0442\u043d\u044b\u0445 \u043a\u0430\u043a \u043a\u043e\u043d\u044a\u044e\u0433\u0430\u0442\u044b \u043e\u043b\u0438\u0433\u043e\u043d\u0443\u043a\u043b\u0435\u043e\u0442\u0438\u0434\u043e\u0432 \u0430\u043d\u0442\u0438\u0442\u0435\u043b (AOCsTM), \u0441\u0435\u0433\u043e\u0434\u043d\u044f \u0441\u043e\u043e\u0431\u0449\u0438\u043b\u0430 \u043e \u0441\u0432\u043e\u0438\u0445 \u0434\u043e\u0441\u0442\u0438\u0436\u0435\u043d\u0438\u044f\u0445 \u0438 \u043f\u043b\u0430\u043d\u0430\u0445 \u043d\u0430 2025 \u0433\u043e\u0434, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u0438\u0437\u043c\u0435\u043d\u0438\u0442 \u0441\u0438\u0442\u0443\u0430\u0446\u0438\u044e.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u042d\u0442\u0438 \u0432\u0430\u0436\u043d\u044b\u0435 \u043e\u0436\u0438\u0434\u0430\u0435\u043c\u044b\u0435 \u0432\u0435\u0445\u0438 \u0432\u043a\u043b\u044e\u0447\u0430\u044e\u0442 \u0437\u0430\u0432\u0435\u0440\u0448\u0435\u043d\u0438\u0435 \u0442\u0440\u0435\u0445 \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b\u044c\u043d\u044b\u0445 \u0440\u0435\u0433\u0438\u0441\u0442\u0440\u0430\u0446\u0438\u043e\u043d\u043d\u044b\u0445 \u043f\u0440\u043e\u0433\u0440\u0430\u043c\u043c, \u043f\u043e\u0434\u0430\u0447\u0443 \u0437\u0430\u044f\u0432\u043a\u0438 \u043d\u0430 \u043f\u043e\u043b\u0443\u0447\u0435\u043d\u0438\u0435 \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u043b\u0438\u0446\u0435\u043d\u0437\u0438\u0438 (BLA) \u0434\u043b\u044f delpacibart zotadirsen (del-zota) \u0434\u043b\u044f \u043b\u044e\u0434\u0435\u0439 \u0441 \u043c\u0443\u0442\u0430\u0446\u0438\u044f\u043c\u0438 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430, \u043f\u043e\u0434\u0434\u0430\u044e\u0449\u0438\u043c\u0438\u0441\u044f \u043f\u0440\u043e\u043f\u0443\u0441\u043a\u0443 \u044d\u043a\u0437\u043e\u043d\u0430 44 (DMD44), \u043f\u043e\u0434\u0433\u043e\u0442\u043e\u0432\u043a\u0443 \u043a \u0437\u0430\u043f\u0443\u0441\u043a\u0443 \u043d\u0435\u0441\u043a\u043e\u043b\u044c\u043a\u0438\u0445 \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u043e\u0432 \u043f\u0440\u0438 DMD44, \u043c\u0438\u043e\u0442\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0442\u0438\u043f\u0430 1 (DM1) \u0438 \u043f\u043b\u0435\u0447\u0435-\u043b\u043e\u043f\u0430\u0442\u043e\u0447\u043d\u043e-\u043b\u0438\u0446\u0435\u0432\u043e\u0439 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 (FSHD), \u0430 \u0442\u0430\u043a\u0436\u0435 \u0441\u043e\u0437\u0434\u0430\u043d\u0438\u0435 \u043f\u043e\u043b\u043d\u043e\u0441\u0442\u044c\u044e \u0438\u043d\u0442\u0435\u0433\u0440\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u043e\u0433\u043e \u043c\u0435\u0436\u0434\u0443\u043d\u0430\u0440\u043e\u0434\u043d\u043e\u0433\u043e \u0431\u0438\u0437\u043d\u0435\u0441\u0430 \u0434\u043b\u044f \u043f\u043e\u0434\u0434\u0435\u0440\u0436\u043a\u0438 \u0440\u0430\u0441\u0448\u0438\u0440\u044f\u044e\u0449\u0435\u0433\u043e\u0441\u044f \u043f\u043e\u0440\u0442\u0444\u0435\u043b\u044f AOC \u0432 \u043e\u0431\u043b\u0430\u0441\u0442\u0438 \u043f\u0440\u0435\u0446\u0438\u0437\u0438\u043e\u043d\u043d\u043e\u0439 \u043a\u0430\u0440\u0434\u0438\u043e\u043b\u043e\u0433\u0438\u0438 \u0438 \u043d\u0435\u0440\u0432\u043d\u043e-\u043c\u044b\u0448\u0435\u0447\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439.<\/p>","protected":false},"excerpt":{"rendered":"<p>A biopharmaceutical firm dedicated to developing a novel class of RNA treatments known as Antibody Oligonucleotide Conjugates (AOCsTM), Avidity Biosciences, Inc., today reported its advancements and plans for a game-changing year in 2025. These significant expected milestones include completing three potentially registrational programs, submitting a Biologics License Application (BLA) for delpacibart zotadirsen (del-zota) for individuals [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2357,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[126,128,130,129,66,77],"class_list":["post-2355","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-avidity-biosciences","tag-bla","tag-dm1","tag-dmd44","tag-duchenne-muscular-dystrophy","tag-exon-skipping"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/2355","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/comments?post=2355"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/2355\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media\/2357"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media?parent=2355"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/categories?post=2355"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/tags?post=2355"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}