{"id":2190,"date":"2025-01-02T01:50:35","date_gmt":"2025-01-01T22:50:35","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2190"},"modified":"2025-01-02T02:00:28","modified_gmt":"2025-01-01T23:00:28","slug":"is-duchenne-gene-therapy-a-suitable-treatment-despite-its-immunogenic-class-effect","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ru\/is-duchenne-gene-therapy-a-suitable-treatment-despite-its-immunogenic-class-effect\/","title":{"rendered":"\u042f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u043b\u0438 \u0433\u0435\u043d\u043d\u0430\u044f \u0442\u0435\u0440\u0430\u043f\u0438\u044f \u0414\u044e\u0448\u0435\u043d\u043d\u0430 \u043f\u043e\u0434\u0445\u043e\u0434\u044f\u0449\u0438\u043c \u043c\u0435\u0442\u043e\u0434\u043e\u043c \u043b\u0435\u0447\u0435\u043d\u0438\u044f, \u043d\u0435\u0441\u043c\u043e\u0442\u0440\u044f \u043d\u0430 \u0435\u0435 \u0438\u043c\u043c\u0443\u043d\u043e\u0433\u0435\u043d\u043d\u044b\u0439 \u043a\u043b\u0430\u0441\u0441?"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u041f\u0440\u043e\u0433\u0440\u0435\u0441\u0441\u0438\u0440\u0443\u044e\u0449\u0430\u044f \u043c\u044b\u0448\u0435\u0447\u043d\u0430\u044f \u0441\u043b\u0430\u0431\u043e\u0441\u0442\u044c \u0438 \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u0430\u044f \u0441\u043c\u0435\u0440\u0442\u043d\u043e\u0441\u0442\u044c \u0432 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0435 \u043a\u0430\u0440\u0434\u0438\u043e\u043c\u0438\u043e\u043f\u0430\u0442\u0438\u0438 \u0438\u043b\u0438 \u0440\u0435\u0441\u043f\u0438\u0440\u0430\u0442\u043e\u0440\u043d\u044b\u0445 \u043e\u0441\u043b\u043e\u0436\u043d\u0435\u043d\u0438\u0439 \u044f\u0432\u043b\u044f\u044e\u0442\u0441\u044f \u043e\u0442\u043b\u0438\u0447\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u043c\u0438 \u043f\u0440\u0438\u0437\u043d\u0430\u043a\u0430\u043c\u0438 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430 (\u041c\u0414\u0414), \u0442\u044f\u0436\u0435\u043b\u043e\u0433\u043e \u0425-\u0441\u0446\u0435\u043f\u043b\u0435\u043d\u043d\u043e\u0433\u043e \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f. \u0412 \u043d\u0430\u0441\u0442\u043e\u044f\u0449\u0435\u0435 \u0432\u0440\u0435\u043c\u044f \u043d\u0435 \u0441\u0443\u0449\u0435\u0441\u0442\u0432\u0443\u0435\u0442 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430 \u043e\u0442 \u041c\u0414\u0414, \u0438 \u043e\u0441\u043d\u043e\u0432\u043d\u043e\u0435 \u0432\u043d\u0438\u043c\u0430\u043d\u0438\u0435 \u0432 \u0441\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u043e\u043c \u043b\u0435\u0447\u0435\u043d\u0438\u0438 \u0443\u0434\u0435\u043b\u044f\u0435\u0442\u0441\u044f \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u043c\u0443 \u043b\u0435\u0447\u0435\u043d\u0438\u044e. \u0413\u0435\u043d\u043d\u0430\u044f \u0442\u0435\u0440\u0430\u043f\u0438\u044f \u043c\u043e\u0436\u0435\u0442 \u0431\u043e\u043b\u0435\u0435 \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e \u0432\u043e\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u043e\u0432\u0430\u0442\u044c \u043d\u0430 \u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0443\u044e \u043f\u0440\u0438\u0447\u0438\u043d\u0443 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f, \u043f\u0440\u0438\u043c\u0435\u043d\u044f\u044f \u0438\u043c\u043c\u0443\u043d\u043e\u0441\u0443\u043f\u0440\u0435\u0441\u0441\u0438\u0432\u043d\u044b\u0435 \u043c\u0435\u0440\u044b \u0438 \u043e\u043f\u0442\u0438\u043c\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0435 \u0432\u0435\u043a\u0442\u043e\u0440\u043d\u044b\u0435 \u043a\u043e\u043d\u0441\u0442\u0440\u0443\u043a\u0446\u0438\u0438.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u041a\u0430\u043a\u043e\u0432\u044b \u044d\u0444\u0444\u0435\u043a\u0442\u044b \u0433\u0435\u043d\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u043f\u0440\u0438 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u0438 \u0414\u044e\u0448\u0435\u043d\u043d\u0430 (\u041c\u0414\u0414), \u0440\u0430\u0431\u043e\u0442\u0430\u044e\u0442 \u043b\u0438 \u0433\u0435\u043d\u043d\u044b\u0435 \u0442\u0435\u0440\u0430\u043f\u0438\u0438? \u0412\u043e\u0442 \u043a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u043d\u044b\u0439 \u0430\u043d\u0430\u043b\u0438\u0437.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.tandfonline.com\/eprint\/BFZQKYN3YY3AHAVX9S27\/full?target=10.1080\/14740338.2024.2447072\" target=\"_blank\" rel=\"noreferrer noopener\">\u0427\u0438\u0442\u0430\u0442\u044c \u0434\u0430\u043b\u0435\u0435<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/x.com\/ToshifumiYokota\" target=\"_blank\" rel=\"noreferrer noopener\">\u0421\u043b\u0435\u0434\u0443\u0439\u0442\u0435 \u0437\u0430 \u043f\u0440\u043e\u0444\u0435\u0441\u0441\u043e\u0440\u043e\u043c \u0422\u043e\u0448\u0438 \u0401\u043a\u043e\u0442\u0430<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Progressive muscle weakness and eventual mortality as a result of cardiomyopathy or respiratory complications are the hallmarks of Duchenne muscular dystrophy (DMD), a severe X-linked disorder. At present, there is no cure for DMD, and the primary focus of standard treatments is on symptom management. Gene therapies can more effectively address the genetic cause of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2192,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[66,33,72,61],"class_list":["post-2190","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-duchenne-muscular-dystrophy","tag-elevidys","tag-gene-editing","tag-gene-therapy"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/2190","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/comments?post=2190"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/posts\/2190\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media\/2192"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/media?parent=2190"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/categories?post=2190"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ru\/wp-json\/wp\/v2\/tags?post=2190"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}