{"id":2438,"date":"2025-01-15T12:28:10","date_gmt":"2025-01-15T09:28:10","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2438"},"modified":"2025-01-15T12:28:12","modified_gmt":"2025-01-15T09:28:12","slug":"the-fda-designates-ips-hearts-givi-mpc-stem-cell-therapy-for-becker-muscular-dystrophy-an-orphan-drug","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/pt\/the-fda-designates-ips-hearts-givi-mpc-stem-cell-therapy-for-becker-muscular-dystrophy-an-orphan-drug\/","title":{"rendered":"O FDA designa a terapia com c\u00e9lulas-tronco GIVI-MPC da IPS HEART para distrofia muscular de Becker como um medicamento \u00f3rf\u00e3o"},"content":{"rendered":"<p class=\"wp-block-paragraph\">O FDA recebeu a designa\u00e7\u00e3o de medicamento \u00f3rf\u00e3o (ODD) do IPS HEART para GIVI-MPCs devido \u00e0 sua capacidade excepcional de produzir novos m\u00fasculos com distrofina de comprimento total em pacientes com distrofia muscular de Becker (BMD).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Foi agora demonstrado pelo IPS HEART que GIVI-MPCs produzem novo m\u00fasculo humano com distrofina humana de comprimento total em um modelo murino de sarcopenia, camundongos jovens e muito velhos com Distrofia Muscular de Duchenne (DMD) e porcos distr\u00f3ficos. A fim de demonstrar o potencial excepcional da plataforma GIVI-MPCs para reverter doen\u00e7as debilitantes, o FDA concedeu anteriormente a Designa\u00e7\u00e3o de Medicamento \u00d3rf\u00e3o para DMD aos GIVI-MPCs.<\/p>","protected":false},"excerpt":{"rendered":"<p>The FDA has granted IPS HEART Orphan Drug Designation (ODD) for GIVI-MPCs because of its exceptional capacity to produce new muscle with full length dystrophin in patients with Becker Muscular Dystrophy (BMD). It has now been demonstrated by IPS HEART that GIVI-MPCs produce new human muscle with full length human dystrophin in a mouse model [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2441,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[67,73,88,160,161],"class_list":["post-2438","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-becker-muscular-dystrophy","tag-dystrophin","tag-fda","tag-givi-mpc","tag-ips-heart"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/posts\/2438","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/comments?post=2438"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/posts\/2438\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/media\/2441"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/media?parent=2438"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/categories?post=2438"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/pt\/wp-json\/wp\/v2\/tags?post=2438"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}