{"id":8854,"date":"2026-10-14T11:55:39","date_gmt":"2026-10-14T08:55:39","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=8854"},"modified":"2026-10-14T11:55:43","modified_gmt":"2026-10-14T08:55:43","slug":"sapreme-therapeutics-spm-2551-dystrophin-restoration-duchenne","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/hi\/sapreme-therapeutics-spm-2551-dystrophin-restoration-duchenne\/","title":{"rendered":"Sapreme Therapeutics \u0928\u0947 \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0930\u094b\u0917 \u092e\u0947\u0902 SPM-2551 \u0915\u0947 \u0938\u093e\u0925 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u0940 \u092e\u091c\u092c\u0942\u0924 \u092a\u094d\u0930\u0940\u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u092c\u0939\u093e\u0932\u0940 \u0915\u0940 \u0930\u093f\u092a\u094b\u0930\u094d\u091f \u0926\u0940 \u0939\u0948\u0964"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>Sapreme Therapeutics \u0928\u0947 SPM-2551 \u0915\u0947 \u0932\u093f\u090f \u0906\u0936\u093e\u091c\u0928\u0915 \u092a\u094d\u0930\u0940\u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u0915\u0940 \u0918\u094b\u0937\u0923\u093e \u0915\u0940 \u0939\u0948, \u091c\u094b \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 (\u0921\u094d\u092f\u0942\u0936\u0947\u0928) \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u092a\u094d\u0930\u093e\u092f\u094b\u0917\u093f\u0915 \u0909\u092a\u091a\u093e\u0930 \u0939\u0948 \u091c\u094b \u090f\u0915\u094d\u0938\u0949\u0928-\u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0924\u0915\u0928\u0940\u0915 \u0914\u0930 \u0906\u0930\u090f\u0928\u090f-\u0906\u0927\u093e\u0930\u093f\u0924 \u0926\u0935\u093e\u0913\u0902 \u0915\u093e \u0909\u092a\u092f\u094b\u0917 \u0915\u0930\u0924\u093e \u0939\u0948, \u091c\u093f\u0938\u092e\u0947\u0902 \u090f\u0902\u091f\u0940\u0938\u0947\u0902\u0938 \u0911\u0932\u093f\u0917\u094b\u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u092f\u094b\u091f\u093e\u0907\u0921\u094d\u0938 (\u090f\u090f\u0938\u0913) \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902\u0964.<\/strong> \u0915\u0902\u092a\u0928\u0940 \u0928\u0947 \u0913\u0932\u093f\u0917\u094b\u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u092f\u094b\u091f\u093e\u0907\u0921 \u0925\u0947\u0930\u0947\u092a\u094d\u092f\u0942\u091f\u093f\u0915\u094d\u0938 \u0938\u094b\u0938\u093e\u0907\u091f\u0940 (\u0913\u091f\u0940\u090f\u0938) 2026 \u0915\u0940 22\u0935\u0940\u0902 \u0935\u093e\u0930\u094d\u0937\u093f\u0915 \u092c\u0948\u0920\u0915 \u092e\u0947\u0902 \u0928\u090f \u0928\u093f\u0937\u094d\u0915\u0930\u094d\u0937 \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924 \u0915\u093f\u090f\u0964 \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u0938\u0947 \u092a\u0924\u093e \u091a\u0932\u093e \u0915\u093f \u092a\u094d\u0930\u0940\u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0949\u0921\u0932 \u092e\u0947\u0902 \u090f\u0915\u0932 \u0915\u092e \u0916\u0941\u0930\u093e\u0915 \u0915\u0947 \u092c\u093e\u0926 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u092e\u0947\u0902 \u092a\u0930\u094d\u092f\u093e\u092a\u094d\u0924 \u0935\u0943\u0926\u094d\u0927\u093f \u0939\u0941\u0908\u0964.<\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>\u0935\u093f\u0937\u092f\u0938\u0942\u091a\u0940<\/h2><nav><ul><li><a href=\"#how-does-spm-2551-work\">\u090f\u0938\u092a\u0940\u090f\u092e-2551 \u0915\u0948\u0938\u0947 \u0915\u093e\u092e \u0915\u0930\u0924\u093e \u0939\u0948?<\/a><\/li><li><a href=\"#dystrophin-increased-to-more-than-35-and-55-of-normal-levels\">\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u093e \u0938\u094d\u0924\u0930 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0938\u094d\u0924\u0930 \u0938\u0947 35% \u0914\u0930 55% \u0938\u0947 \u0905\u0927\u093f\u0915 \u092c\u0922\u093c \u0917\u092f\u093e\u0964<\/a><\/li><li><a href=\"#when-will-human-trials-begin\">\u092e\u093e\u0928\u0935 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u092c \u0936\u0941\u0930\u0942 \u0939\u094b\u0902\u0917\u0947?<\/a><\/li><li><a href=\"#what-do-these-results-mean-for-duchenne\">\u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0930\u094b\u0917 \u0915\u0947 \u0932\u093f\u090f \u0907\u0928 \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u0915\u093e \u0915\u094d\u092f\u093e \u0905\u0930\u094d\u0925 \u0939\u0948?<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<h2 id=\"how-does-spm-2551-work\" class=\"wp-block-heading\">\u090f\u0938\u092a\u0940\u090f\u092e-2551 \u0915\u0948\u0938\u0947 \u0915\u093e\u092e \u0915\u0930\u0924\u093e \u0939\u0948?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0930\u094b\u0917 \u0906\u0928\u0941\u0935\u0902\u0936\u093f\u0915 \u092a\u0930\u093f\u0935\u0930\u094d\u0924\u0928\u094b\u0902 \u0915\u0947 \u0915\u093e\u0930\u0923 \u0939\u094b\u0924\u093e \u0939\u0948 \u091c\u094b \u0936\u0930\u0940\u0930 \u0915\u094b \u092a\u0930\u094d\u092f\u093e\u092a\u094d\u0924 \u092e\u093e\u0924\u094d\u0930\u093e \u092e\u0947\u0902 \u0915\u093e\u0930\u094d\u092f\u093e\u0924\u094d\u092e\u0915 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u093e \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u0915\u0930\u0928\u0947 \u0938\u0947 \u0930\u094b\u0915\u0924\u093e \u0939\u0948, \u091c\u094b \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u0940 \u0924\u093e\u0915\u0924 \u0914\u0930 \u0938\u0902\u0930\u091a\u0928\u093e \u0915\u094b \u092c\u0928\u093e\u090f \u0930\u0916\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0906\u0935\u0936\u094d\u092f\u0915 \u092a\u094d\u0930\u094b\u091f\u0940\u0928 \u0939\u0948\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u090f\u0938\u092a\u0940\u090f\u092e-2551 \u092e\u0947\u0902 \u0924\u0940\u0928 \u0918\u091f\u0915 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902: \u090f\u0915 \u090f\u0902\u091f\u0940\u092c\u0949\u0921\u0940 \u091c\u094b \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u0940 \u090a\u0924\u0915 \u0915\u094b \u0932\u0915\u094d\u0937\u093f\u0924 \u0915\u0930\u0924\u0940 \u0939\u0948, \u090f\u0915 \u090f\u0915\u094d\u0938\u0949\u0928-\u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u090f\u0902\u091f\u0940\u0938\u0947\u0902\u0938 \u0911\u0932\u093f\u0917\u094b\u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u092f\u094b\u091f\u093e\u0907\u0921 \u091c\u093f\u0938\u0947 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u0915\u094b \u092c\u0939\u093e\u0932 \u0915\u0930\u0928\u0947 \u092e\u0947\u0902 \u092e\u0926\u0926 \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0921\u093f\u091c\u093c\u093e\u0907\u0928 \u0915\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948, \u0914\u0930 \u0938\u0948\u092a\u094d\u0930\u0940\u092e \u0915\u0940 \u092e\u093e\u0932\u093f\u0915\u093e\u0928\u093e \u090f\u0938\u092a\u0940\u091f\u0940 \u0924\u0915\u0928\u0940\u0915\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u090f\u0938\u092a\u0940\u091f\u0940 \u0924\u0915\u0928\u0940\u0915 \u0906\u0930\u090f\u0928\u090f-\u0906\u0927\u093e\u0930\u093f\u0924 \u0926\u0935\u093e\u0913\u0902 \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u092c\u0921\u093c\u0940 \u091a\u0941\u0928\u094c\u0924\u0940 \u0915\u093e \u0938\u092e\u093e\u0927\u093e\u0928 \u0915\u0930\u0928\u0947 \u0915\u093e \u0932\u0915\u094d\u0937\u094d\u092f \u0930\u0916\u0924\u0940 \u0939\u0948\u0964 \u0915\u094b\u0936\u093f\u0915\u093e \u092e\u0947\u0902 \u092a\u094d\u0930\u0935\u0947\u0936 \u0915\u0930\u0928\u0947 \u0915\u0947 \u092c\u093e\u0926, \u092f\u0947 \u0926\u0935\u093e\u090f\u0902 \u090f\u0902\u0921\u094b\u0938\u094b\u092e \u0928\u093e\u092e\u0915 \u091b\u094b\u091f\u0940 \u0938\u0902\u0930\u091a\u0928\u093e\u0913\u0902 \u092e\u0947\u0902 \u092b\u0902\u0938 \u0938\u0915\u0924\u0940 \u0939\u0948\u0902, \u091c\u093f\u0938\u0938\u0947 \u0935\u0947 \u0905\u092a\u0928\u0947 \u0932\u0915\u094d\u0937\u093f\u0924 \u0938\u094d\u0925\u093e\u0928 \u0924\u0915 \u0928\u0939\u0940\u0902 \u092a\u0939\u0941\u0902\u091a \u092a\u093e\u0924\u0940\u0902\u0964 \u0938\u0948\u092a\u094d\u0930\u0940\u092e \u0915\u0940 \u0924\u0915\u0928\u0940\u0915 \u0907\u0938 \u0924\u0930\u0939 \u0938\u0947 \u0921\u093f\u091c\u093c\u093e\u0907\u0928 \u0915\u0940 \u0917\u0908 \u0939\u0948 \u0915\u093f \u0926\u0935\u093e \u0915\u093e \u0905\u0927\u093f\u0915 \u0939\u093f\u0938\u094d\u0938\u093e \u0907\u0928 \u0938\u0902\u0930\u091a\u0928\u093e\u0913\u0902 \u0938\u0947 \u092c\u093e\u0939\u0930 \u0928\u093f\u0915\u0932\u0915\u0930 \u0915\u094b\u0936\u093f\u0915\u093e \u0915\u0947 \u0905\u0902\u0926\u0930 \u0915\u093e\u092e \u0915\u0930 \u0938\u0915\u0947\u0964.<\/p>\n\n\n\n<h2 id=\"dystrophin-increased-to-more-than-35-and-55-of-normal-levels\" class=\"wp-block-heading\">\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u093e \u0938\u094d\u0924\u0930 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0938\u094d\u0924\u0930 \u0938\u0947 35% \u0914\u0930 55% \u0938\u0947 \u0905\u0927\u093f\u0915 \u092c\u0922\u093c \u0917\u092f\u093e\u0964<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0938\u092c\u0938\u0947 \u0909\u0932\u094d\u0932\u0947\u0916\u0928\u0940\u092f \u0928\u093f\u0937\u094d\u0915\u0930\u094d\u0937 \u092a\u094d\u0930\u094b\u092b\u0947\u0938\u0930 \u090f\u0928\u0940\u092e\u0940\u0915\u0947 \u0906\u0930\u094d\u091f\u094d\u0938\u092e\u093e-\u0930\u0938 \u0915\u0940 \u092a\u094d\u0930\u092f\u094b\u0917\u0936\u093e\u0932\u093e\u0913\u0902 \u092e\u0947\u0902 \u0935\u093f\u0915\u0938\u093f\u0924 \u0915\u093f\u090f \u0917\u090f \u092e\u093e\u0928\u0935\u0940\u0915\u0943\u0924 \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u093e\u0909\u0938 \u092e\u0949\u0921\u0932 \u0938\u0947 \u092a\u094d\u0930\u093e\u092a\u094d\u0924 \u0939\u0941\u090f\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u090f\u0938\u092a\u0940\u090f\u092e-2551 \u0928\u0947 \u0924\u0941\u0932\u0928\u093e\u0924\u094d\u092e\u0915 \u0911\u0932\u093f\u0917\u094b\u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u092f\u094b\u091f\u093e\u0907\u0921\u094d\u0938 \u0915\u0940 \u0924\u0941\u0932\u0928\u093e \u092e\u0947\u0902 5-10 \u0917\u0941\u0928\u093e \u0905\u0927\u093f\u0915 \u090f\u0915\u094d\u0938\u0949\u0928 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0939\u093e\u0938\u093f\u0932 \u0915\u0940, \u092f\u0939\u093e\u0902 \u0924\u0915 \u0915\u093f \u0932\u0917\u092d\u0917 \u0926\u0938 \u0917\u0941\u0928\u093e \u0915\u092e \u090f\u0902\u091f\u0940\u0938\u0947\u0902\u0938 \u0911\u0932\u093f\u0917\u094b\u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u092f\u094b\u091f\u093e\u0907\u0921 \u0916\u0941\u0930\u093e\u0915 \u0915\u093e \u0909\u092a\u092f\u094b\u0917 \u0915\u0930\u0928\u0947 \u092a\u0930 \u092d\u0940\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u0947 \u092a\u0930\u093f\u0923\u093e\u092e \u0935\u093f\u0936\u0947\u0937 \u0930\u0942\u092a \u0938\u0947 \u0909\u0924\u094d\u0938\u093e\u0939\u091c\u0928\u0915 \u0925\u0947:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>1 \u092e\u093f\u0932\u0940\u0917\u094d\u0930\u093e\u092e\/\u0915\u093f\u0932\u094b\u0917\u094d\u0930\u093e\u092e \u092a\u0930: \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0938\u094d\u0924\u0930 \u0938\u0947 351\u091f\u0940\u092a\u0940179\u091f\u0940 \u0905\u0927\u093f\u0915 \u0939\u094b \u0917\u092f\u093e\u0964.<\/li>\n\n\n\n<li>3 \u092e\u093f\u0932\u0940\u0917\u094d\u0930\u093e\u092e\/\u0915\u093f\u0932\u094b\u0917\u094d\u0930\u093e\u092e \u092a\u0930: \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0938\u094d\u0924\u0930 \u0938\u0947 55% \u0938\u0947 \u0905\u0927\u093f\u0915 \u0939\u094b \u0917\u092f\u093e\u0964.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u092f\u0947 \u092a\u0930\u093f\u0923\u093e\u092e \u090f\u0915 \u092c\u093e\u0930 \u0926\u0935\u093e \u0926\u0947\u0928\u0947 \u0915\u0947 56 \u0926\u093f\u0928 \u092c\u093e\u0926 \u092e\u093e\u092a\u0947 \u0917\u090f\u0964 \u0928\u093f\u0937\u094d\u0915\u0930\u094d\u0937\u094b\u0902 \u0938\u0947 \u092a\u0924\u093e \u091a\u0932\u0924\u093e \u0939\u0948 \u0915\u093f \u0905\u0927\u093f\u0915 \u092e\u093e\u0924\u094d\u0930\u093e \u092e\u0947\u0902 \u0926\u0935\u093e \u0926\u0947\u0928\u0947 \u0938\u0947 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u0940 \u092c\u0939\u093e\u0932\u0940 \u0905\u0927\u093f\u0915 \u0939\u0941\u0908 \u0914\u0930 \u092f\u0939 \u092a\u094d\u0930\u092d\u093e\u0935 \u0905\u0935\u0932\u094b\u0915\u0928 \u0905\u0935\u0927\u093f \u0915\u0947 \u0926\u094c\u0930\u093e\u0928 \u092c\u0928\u093e \u0930\u0939\u093e\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0938\u0948\u092a\u094d\u0930\u0940\u092e \u0928\u0947 \u0915\u0939\u093e \u0939\u0948 \u0915\u093f \u0909\u0938\u0915\u093e \u0935\u093f\u0915\u093e\u0938 \u0932\u0915\u094d\u0937\u094d\u092f \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u0947 \u0938\u094d\u0924\u0930 \u0915\u094b \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0938\u094d\u0924\u0930 \u0938\u0947 15% \u0938\u0947 \u0905\u0927\u093f\u0915 \u0924\u0915 \u092c\u0939\u093e\u0932 \u0915\u0930\u0928\u093e \u0939\u0948\u0964 \u0930\u093f\u092a\u094b\u0930\u094d\u091f \u0915\u093f\u090f \u0917\u090f \u092a\u094d\u0930\u0940\u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u092e\u0947\u0902 \u0926\u094b\u0928\u094b\u0902 \u092a\u0930\u0940\u0915\u094d\u0937\u0923\u093f\u0924 \u0916\u0941\u0930\u093e\u0915\u094b\u0902 \u092a\u0930 \u092f\u0939 \u0932\u0915\u094d\u0937\u094d\u092f \u092a\u093e\u0930 \u0939\u094b \u0917\u092f\u093e\u0964 \u0939\u093e\u0932\u093e\u0902\u0915\u093f, \u092f\u0947 \u0928\u093f\u0937\u094d\u0915\u0930\u094d\u0937 \u090f\u0915 \u092a\u0936\u0941 \u092e\u0949\u0921\u0932 \u0938\u0947 \u092a\u094d\u0930\u093e\u092a\u094d\u0924 \u0939\u0941\u090f \u0939\u0948\u0902 \u0914\u0930 \u092f\u0939 \u0938\u094d\u0925\u093e\u092a\u093f\u0924 \u0928\u0939\u0940\u0902 \u0915\u0930\u0924\u0947 \u0915\u093f \u092e\u0928\u0941\u0937\u094d\u092f\u094b\u0902 \u092e\u0947\u0902 \u0909\u092a\u091a\u093e\u0930 \u0915\u0948\u0938\u093e \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u0928 \u0915\u0930\u0947\u0917\u093e\u0964.<\/p>\n\n\n\n<h2 id=\"when-will-human-trials-begin\" class=\"wp-block-heading\">\u092e\u093e\u0928\u0935 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u092c \u0936\u0941\u0930\u0942 \u0939\u094b\u0902\u0917\u0947?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0938\u0948\u092a\u094d\u0930\u0940\u092e 2027 \u092e\u0947\u0902 \u090f\u0938\u092a\u0940\u090f\u092e-2551 \u0915\u0947 \u0932\u093f\u090f \u0906\u0908\u090f\u0928\u0921\u0940-\u0938\u0915\u094d\u0937\u092e \u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u0940 \u0924\u0948\u092f\u093e\u0930\u0940 \u0915\u0930 \u0930\u0939\u0940 \u0939\u0948\u0964.<\/strong> \u0907\u0928 \u0905\u0927\u094d\u092f\u092f\u0928\u094b\u0902 \u0915\u093e \u0909\u0926\u094d\u0926\u0947\u0936\u094d\u092f \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0936\u0941\u0930\u0942 \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0938\u0902\u092d\u093e\u0935\u093f\u0924 \u0906\u0935\u0947\u0926\u0928 \u0915\u093e \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0928\u0947 \u0939\u0947\u0924\u0941 \u0906\u0935\u0936\u094d\u092f\u0915 \u0921\u0947\u091f\u093e \u0909\u0924\u094d\u092a\u0928\u094d\u0928 \u0915\u0930\u0928\u093e \u0939\u0948\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0915\u0902\u092a\u0928\u0940 \u0928\u0947 \u092e\u093e\u0928\u0935 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0936\u0941\u0930\u0942 \u0915\u0930\u0928\u0947 \u0915\u0940 \u0915\u094b\u0908 \u0928\u093f\u0936\u094d\u091a\u093f\u0924 \u0924\u093e\u0930\u0940\u0916 \u0918\u094b\u0937\u093f\u0924 \u0928\u0939\u0940\u0902 \u0915\u0940 \u0939\u0948\u0964.<\/strong> \u0907\u0938\u0915\u0940 \u0935\u0930\u094d\u0924\u092e\u093e\u0928 \u092f\u094b\u091c\u0928\u093e \u0906\u0935\u0936\u094d\u092f\u0915 \u092a\u0942\u0930\u094d\u0935-\u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u0924\u0948\u092f\u093e\u0930\u093f\u092f\u094b\u0902 \u0938\u0947 \u0936\u0941\u0930\u0942 \u0915\u0930\u0924\u0947 \u0939\u0941\u090f, \u0909\u092e\u094d\u092e\u0940\u0926\u0935\u093e\u0930 \u0915\u094b \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u0935\u093f\u0915\u093e\u0938 \u0915\u0940 \u0913\u0930 \u0906\u0917\u0947 \u092c\u0922\u093c\u093e\u0928\u093e \u0939\u0948\u0964.<\/p>\n\n\n\n<h2 id=\"what-do-these-results-mean-for-duchenne\" class=\"wp-block-heading\">\u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0930\u094b\u0917 \u0915\u0947 \u0932\u093f\u090f \u0907\u0928 \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u0915\u093e \u0915\u094d\u092f\u093e \u0905\u0930\u094d\u0925 \u0939\u0948?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u090f\u0938\u092a\u0940\u090f\u092e-2551 \u0928\u0947 \u090f\u0915 \u092a\u094d\u0930\u0940\u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u092e\u0949\u0921\u0932 \u092e\u0947\u0902 \u090f\u0915\u0932 \u0915\u092e \u0916\u0941\u0930\u093e\u0915 \u0915\u0947 \u092c\u093e\u0926 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u0940 \u092a\u0930\u094d\u092f\u093e\u092a\u094d\u0924 \u092c\u0939\u093e\u0932\u0940 \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u093f\u0924 \u0915\u0940 \u0939\u0948\u0964 \u0907\u0938\u0915\u0940 \u0932\u0915\u094d\u0937\u093f\u0924 \u0921\u093f\u0932\u0940\u0935\u0930\u0940 \u0914\u0930 \u090f\u0902\u0921\u094b\u0938\u094b\u092e\u0932 \u090f\u0938\u094d\u0915\u0947\u092a \u0924\u0915\u0928\u0940\u0915 \u0915\u092e \u0916\u0941\u0930\u093e\u0915 \u0914\u0930 \u0938\u0902\u092d\u093e\u0935\u093f\u0924 \u0930\u0942\u092a \u0938\u0947 \u092a\u094d\u0930\u0936\u093e\u0938\u0928 \u0915\u0947 \u092c\u0940\u091a \u0932\u0902\u092c\u0947 \u0905\u0902\u0924\u0930\u093e\u0932 \u0915\u0947 \u0938\u093e\u0925 \u092d\u0940 \u092a\u094d\u0930\u092d\u093e\u0935 \u092a\u094d\u0930\u093e\u092a\u094d\u0924 \u0915\u0930\u0928\u0947 \u092e\u0947\u0902 \u0938\u0939\u093e\u092f\u0915 \u0939\u094b \u0938\u0915\u0924\u0940 \u0939\u0948\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0905\u0917\u0932\u093e \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0915\u0926\u092e \u092f\u0939 \u0928\u093f\u0930\u094d\u0927\u093e\u0930\u093f\u0924 \u0915\u0930\u0928\u093e \u0939\u094b\u0917\u093e \u0915\u093f \u0915\u094d\u092f\u093e \u0907\u0928 \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u0915\u094b \u092e\u0928\u0941\u0937\u094d\u092f\u094b\u0902 \u092e\u0947\u0902 \u0938\u0941\u0930\u0915\u094d\u0937\u093f\u0924 \u0914\u0930 \u092a\u094d\u0930\u092d\u093e\u0935\u0940 \u0922\u0902\u0917 \u0938\u0947 \u0926\u094b\u0939\u0930\u093e\u092f\u093e \u091c\u093e \u0938\u0915\u0924\u093e \u0939\u0948\u0964 \u091c\u092c \u0924\u0915 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u092f\u0939 \u092a\u094d\u0930\u092e\u093e\u0923 \u092a\u094d\u0930\u0926\u093e\u0928 \u0928\u0939\u0940\u0902 \u0915\u0930\u0924\u0947, \u090f\u0938\u092a\u0940\u090f\u092e-2551 \u090f\u0915 \u092a\u094d\u0930\u093e\u092f\u094b\u0917\u093f\u0915 \u0909\u092a\u091a\u093e\u0930 \u092c\u0928\u093e \u0930\u0939\u0947\u0917\u093e, \u0914\u0930 \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0930\u094b\u0917 \u0938\u0947 \u092a\u0940\u0921\u093c\u093f\u0924 \u0932\u094b\u0917\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0907\u0938\u0915\u0947 \u0938\u0902\u092d\u093e\u0935\u093f\u0924 \u0932\u093e\u092d \u0905\u092d\u0940 \u0924\u0915 \u0938\u094d\u0925\u093e\u092a\u093f\u0924 \u0928\u0939\u0940\u0902 \u0939\u0941\u090f \u0939\u0948\u0902\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0914\u0930 \u0922\u0942\u0902\u0922\u0947\u0902<\/strong>:\u00a0<a href=\"https:\/\/dmdwarrior.com\/clinical-trials\/map\/\" target=\"_blank\" rel=\"noopener\">\u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u091f\u094d\u0930\u093e\u092f\u0932 \u0938\u094d\u0925\u093e\u0928\u094b\u0902 \u0915\u093e \u092e\u093e\u0928\u091a\u093f\u0924\u094d\u0930<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>","protected":false},"excerpt":{"rendered":"<p>Sapreme Therapeutics has announced promising preclinical results for SPM-2551, an experimental treatment for Duchenne muscular dystrophy (Duchenne) that uses exon-skipping technology and RNA-based medicines, including antisense oligonucleotides (ASOs). The company presented the new findings at the 22nd Annual Meeting of the Oligonucleotide Therapeutics Society (OTS) 2026. The results showed substantial increases in dystrophin production following [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":8855,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[929,77,931,930,928,932,927],"class_list":["post-8854","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-dystrophin-restoration","tag-exon-skipping","tag-oligonucleotide-therapeutics","tag-rna-therapeutics","tag-sapreme-therapeutics","tag-sirna","tag-spm-2551"],"subtitle":"Sapreme Therapeutics' SPM-2551 \u0928\u0947 \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0949\u0921\u0932 \u092e\u0947\u0902 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u0947 \u0938\u094d\u0924\u0930 \u092e\u0947\u0902 \u0909\u0932\u094d\u0932\u0947\u0916\u0928\u0940\u092f \u0935\u0943\u0926\u094d\u0927\u093f \u0939\u093e\u0938\u093f\u0932 \u0915\u0940\u0964 1 \u0914\u0930 3 \u092e\u093f\u0932\u0940\u0917\u094d\u0930\u093e\u092e\/\u0915\u093f\u0932\u094b\u0917\u094d\u0930\u093e\u092e \u0915\u0940 \u0916\u0941\u0930\u093e\u0915 \u092a\u0930, \u0938\u094d\u0924\u0930 \u0915\u094d\u0930\u092e\u0936\u0903 35% \u0914\u0930 55% \u0915\u0947 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0938\u094d\u0924\u0930 \u0938\u0947 \u0905\u0927\u093f\u0915 \u0939\u094b \u0917\u090f\u0964 \u0915\u094d\u092f\u093e \u090f\u0915\u094d\u0938\u0949\u0928-\u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0924\u0915\u0928\u0940\u0915 2027 \u0924\u0915 \u092e\u093e\u0928\u0935 \u092a\u0930\u0940\u0915\u094d\u0937\u0923\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0924\u0948\u092f\u093e\u0930 \u0939\u094b \u0938\u0915\u0924\u0940 \u0939\u0948?","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/8854","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/comments?post=8854"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/8854\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media\/8855"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media?parent=8854"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/categories?post=8854"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/tags?post=8854"}],"curies":[{"name":"\u0921\u092c\u094d\u0932\u094d\u092f\u0942\u092a\u0940","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}