{"id":7974,"date":"2026-05-27T17:33:34","date_gmt":"2026-05-27T14:33:34","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=7974"},"modified":"2026-05-27T17:33:35","modified_gmt":"2026-05-27T14:33:35","slug":"dyne-251-z-rostudirsen-phase-3-forzetto-clinical-trial","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/hi\/dyne-251-z-rostudirsen-phase-3-forzetto-clinical-trial\/","title":{"rendered":"DMD \u0915\u0947 \u0932\u093f\u090f Z-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0947\u0928 \u0915\u0947 DYNE-251 \u091a\u0930\u0923 3 \u0914\u0930 FORZETTO \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u0940 \u0906\u0927\u093f\u0915\u093e\u0930\u093f\u0915 \u0936\u0941\u0930\u0941\u0906\u0924 \u0939\u094b \u0917\u0908 \u0939\u0948\u0964"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>Dyne Therapeutics \u0928\u0947 DMD \u0915\u0947 \u0932\u093f\u090f Z-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0947\u0928 \u0915\u0947 Dyne Therapeutics \u091a\u0930\u0923 3 FORZETTO \u092a\u0930\u0940\u0915\u094d\u0937\u0923 (NCT07608432) \u0915\u0940 \u0936\u0941\u0930\u0941\u0906\u0924 \u0915\u0940 \u0918\u094b\u0937\u0923\u093e \u0915\u0940 \u0939\u0948, \u091c\u094b \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 (DMD) \u0938\u0947 \u092a\u094d\u0930\u092d\u093e\u0935\u093f\u0924 \u092a\u0930\u093f\u0935\u093e\u0930\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u0914\u0930 \u092c\u0921\u093c\u093e \u0915\u0926\u092e \u0939\u0948\u0964.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0935\u0948\u0936\u094d\u0935\u093f\u0915 \u091a\u0930\u0923 3 \u0905\u0927\u094d\u092f\u092f\u0928 \u092e\u0947\u0902 DMD \u0938\u0947 \u092a\u0940\u0921\u093c\u093f\u0924 \u0909\u0928 \u0932\u094b\u0917\u094b\u0902 \u092e\u0947\u0902 z-rostudirsen (DYNE-251) \u0915\u093e \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u0915\u093f\u092f\u093e \u091c\u093e\u090f\u0917\u093e \u091c\u094b \u090f\u0915\u094d\u0938\u0949\u0928 51 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0915\u0947 \u0932\u093f\u090f \u0909\u092a\u092f\u0941\u0915\u094d\u0924 \u0939\u0948\u0902\u0964 \u0915\u0902\u092a\u0928\u0940 \u0907\u0938 \u0924\u093f\u092e\u093e\u0939\u0940 \u0915\u0947 \u0905\u0902\u0924 \u092e\u0947\u0902 \u0924\u094d\u0935\u0930\u093f\u0924 \u0905\u0928\u0941\u092e\u094b\u0926\u0928 \u0915\u0947 \u0932\u093f\u090f US FDA \u0915\u0947 \u0932\u093f\u090f \u092c\u093e\u092f\u094b\u0932\u0949\u091c\u093f\u0915\u094d\u0938 \u0932\u093e\u0907\u0938\u0947\u0902\u0938 \u090f\u092a\u094d\u0932\u0940\u0915\u0947\u0936\u0928 (BLA) \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924 \u0915\u0930\u0928\u0947 \u0915\u0940 \u092d\u0940 \u092f\u094b\u091c\u0928\u093e \u092c\u0928\u093e \u0930\u0939\u0940 \u0939\u0948\u0964 \u0905\u0927\u093f\u0915 \u091c\u093e\u0928\u0947\u0902: <a href=\"https:\/\/dmdwarrior.com\/hi\/biologics-license-application-bla\/\" target=\"_blank\" data-type=\"post\" data-id=\"5027\" rel=\"noreferrer noopener\">\u092c\u0940\u090f\u0932\u090f \u0915\u093e \u092e\u0924\u0932\u092c \u0915\u094d\u092f\u093e \u0939\u0948?<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">FORZETTO \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u093e \u0921\u093f\u091c\u093c\u093e\u0907\u0928 \u0907\u091f\u0932\u0940 \u0915\u0947 \u092b\u094d\u0932\u094b\u0930\u0947\u0902\u0938 \u092e\u0947\u0902 \u0906\u092f\u094b\u091c\u093f\u0924 \u0939\u094b\u0928\u0947 \u0935\u093e\u0932\u0947 19\u0935\u0947\u0902 \u0905\u0902\u0924\u0930\u094d\u0930\u093e\u0937\u094d\u091f\u094d\u0930\u0940\u092f \u0928\u094d\u092f\u0942\u0930\u094b\u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0930\u094b\u0917 \u0915\u093e\u0902\u0917\u094d\u0930\u0947\u0938 (ICNMD) \u0915\u0947 \u0926\u094c\u0930\u093e\u0928 \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924 \u0915\u093f\u092f\u093e \u091c\u093e\u090f\u0917\u093e\u0964.<\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>\u0935\u093f\u0937\u092f\u0938\u0942\u091a\u0940<\/h2><nav><ul><li><a href=\"#what-is-z-rostudirsen-dyne-251\">Z-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0928 (DYNE-251) \u0915\u094d\u092f\u093e \u0939\u0948?<\/a><\/li><li><a href=\"#how-the-forzetto-phase-3-trial-will-work\">FORZETTO \u092b\u0947\u091c 3 \u091f\u094d\u0930\u093e\u092f\u0932 \u0915\u0948\u0938\u0947 \u0915\u093e\u092e \u0915\u0930\u0947\u0917\u093e<\/a><\/li><li><a href=\"#primary-endpoint-focuses-on-muscle-function\">\u092a\u094d\u0930\u093e\u0925\u092e\u093f\u0915 \u0932\u0915\u094d\u0937\u094d\u092f \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u0947 \u0915\u093e\u0930\u094d\u092f \u092a\u0930 \u0915\u0947\u0902\u0926\u094d\u0930\u093f\u0924 \u0939\u0948\u0964<\/a><\/li><li><a href=\"#additional-secondary-endpoints-in-the-forzetto-study\">FORZETTO \u0905\u0927\u094d\u092f\u092f\u0928 \u092e\u0947\u0902 \u0905\u0924\u093f\u0930\u093f\u0915\u094d\u0924 \u0926\u094d\u0935\u093f\u0924\u0940\u092f\u0915 \u0932\u0915\u094d\u0937\u094d\u092f<\/a><\/li><li><a href=\"#fda-alignment-and-accelerated-approval-plans\">FDA \u0938\u0902\u0930\u0947\u0916\u0923 \u0914\u0930 \u0924\u094d\u0935\u0930\u093f\u0924 \u0905\u0928\u0941\u092e\u094b\u0926\u0928 \u092f\u094b\u091c\u0928\u093e\u090f\u0901<\/a><\/li><li><a href=\"#why-the-dyne-therapeutics-phase-3-forzetto-trial-of-z-rostudirsen-for-dmd-matters\">\u0921\u0940\u090f\u092e\u0921\u0940 \u0915\u0947 \u0932\u093f\u090f \u091c\u0947\u0921-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0947\u0928 \u0915\u0947 1\u091f\u0940\u092a\u094045\u091f\u0940 \u092b\u0947\u091c 3 1\u091f\u0940\u092a\u0940135\u091f\u0940 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u093e \u092e\u0939\u0924\u094d\u0935 \u0915\u094d\u092f\u094b\u0902 \u0939\u0948?<\/a><\/li><li><a href=\"#contact-information\">\u0938\u0902\u092a\u0930\u094d\u0915 \u091c\u093e\u0928\u0915\u093e\u0930\u0940<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 id=\"what-is-z-rostudirsen-dyne-251\" class=\"wp-block-heading\">Z-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0928 (DYNE-251) \u0915\u094d\u092f\u093e \u0939\u0948?<\/h2>\n\n\n\n<h3 id=\"a-next-generation-exon-51-skipping-therapy\" class=\"wp-block-heading\">\u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0940 \u090f\u0915\u094d\u0938\u0949\u0928 51 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0925\u0947\u0930\u0947\u092a\u0940<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u091c\u0947\u0921-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0947\u0928, \u091c\u093f\u0938\u0947 DYNE-251 \u0915\u0947 \u0928\u093e\u092e \u0938\u0947 \u092d\u0940 \u091c\u093e\u0928\u093e \u091c\u093e\u0924\u093e \u0939\u0948, \u090f\u0915 \u092a\u094d\u0930\u093e\u092f\u094b\u0917\u093f\u0915 \u091a\u093f\u0915\u093f\u0924\u094d\u0938\u093e \u092a\u0926\u094d\u0927\u0924\u093f \u0939\u0948 \u091c\u093f\u0938\u0947 \u0921\u0940\u090f\u092e\u0921\u0940 \u0909\u0924\u094d\u092a\u0930\u093f\u0935\u0930\u094d\u0924\u0928 \u0935\u093e\u0932\u0947 \u0932\u094b\u0917\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0921\u093f\u091c\u093c\u093e\u0907\u0928 \u0915\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948 \u091c\u094b \u090f\u0915\u094d\u0938\u0949\u0928 51 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0938\u0947 \u0932\u093e\u092d\u093e\u0928\u094d\u0935\u093f\u0924 \u0939\u094b \u0938\u0915\u0924\u0947 \u0939\u0948\u0902\u0964.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0907\u0938 \u0925\u0947\u0930\u0947\u092a\u0940 \u0915\u093e \u0909\u0926\u094d\u0926\u0947\u0936\u094d\u092f \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0914\u0930 \u0915\u0947\u0902\u0926\u094d\u0930\u0940\u092f \u0924\u0902\u0924\u094d\u0930\u093f\u0915\u093e \u0924\u0902\u0924\u094d\u0930 \u092e\u0947\u0902 \u0932\u0917\u092d\u0917 \u092a\u0942\u0930\u094d\u0923 \u0932\u0902\u092c\u093e\u0908 \u0935\u093e\u0932\u0947 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u092a\u094d\u0930\u094b\u091f\u0940\u0928 \u0915\u093e \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u0915\u0930\u0928\u0947 \u092e\u0947\u0902 \u0936\u0930\u0940\u0930 \u0915\u0940 \u092e\u0926\u0926 \u0915\u0930\u0928\u093e \u0939\u0948\u0964 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u094b \u0915\u094d\u0937\u0924\u093f \u0938\u0947 \u092c\u091a\u093e\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0906\u0935\u0936\u094d\u092f\u0915 \u0939\u0948, \u0914\u0930 \u0907\u0938\u0915\u0940 \u0905\u0928\u0941\u092a\u0938\u094d\u0925\u093f\u0924\u093f \u0921\u0940\u090f\u092e\u0921\u0940 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u092e\u0947\u0902 \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u0940 \u092c\u0922\u093c\u0924\u0940 \u0915\u092e\u091c\u094b\u0930\u0940 \u0915\u093e \u0915\u093e\u0930\u0923 \u092c\u0928\u0924\u0940 \u0939\u0948\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Dyne Therapeutics \u0915\u0947 \u0905\u0928\u0941\u0938\u093e\u0930, \u0907\u0938 \u0909\u092a\u091a\u093e\u0930 \u0915\u093e \u0932\u0915\u094d\u0937\u094d\u092f \u0928 \u0915\u0947\u0935\u0932 \u092a\u094d\u0930\u092f\u094b\u0917\u0936\u093e\u0932\u093e \u092c\u093e\u092f\u094b\u092e\u093e\u0930\u094d\u0915\u0930\u094b\u0902 \u092e\u0947\u0902 \u0938\u0941\u0927\u093e\u0930 \u0915\u0930\u0928\u093e \u0939\u0948, \u092c\u0932\u094d\u0915\u093f \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u094b \u092c\u0947\u0939\u0924\u0930 \u0922\u0902\u0917 \u0938\u0947 \u091a\u0932\u0928\u0947-\u092b\u093f\u0930\u0928\u0947, \u092c\u0947\u0939\u0924\u0930 \u0938\u093e\u0902\u0938 \u0932\u0947\u0928\u0947 \u0914\u0930 \u0926\u0948\u0928\u093f\u0915 \u091c\u0940\u0935\u0928 \u0915\u0940 \u0917\u0941\u0923\u0935\u0924\u094d\u0924\u093e \u092e\u0947\u0902 \u0938\u0941\u0927\u093e\u0930 \u0915\u0930\u0928\u0947 \u092e\u0947\u0902 \u092e\u0926\u0926 \u0915\u0930\u0928\u093e \u092d\u0940 \u0939\u0948\u0964.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"847\" height=\"1024\" src=\"https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-847x1024.jpg\" alt=\"\u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u0915\u0947 \u0932\u093f\u090f \u090f\u0915\u094d\u0938\u0949\u0928 51 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0925\u0947\u0930\u0947\u092a\u0940 \u0915\u0947 \u0905\u0928\u0941\u0915\u0942\u0932 \u0909\u0924\u094d\u092a\u0930\u093f\u0935\u0930\u094d\u0924\u0928 \u0914\u0930 \u0935\u093f\u0932\u094b\u092a\u0928\" class=\"wp-image-4526\" title=\"\" srcset=\"https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-847x1024.jpg 847w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-248x300.jpg 248w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-768x929.jpg 768w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-1270x1536.jpg 1270w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-1693x2048.jpg 1693w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-10x12.jpg 10w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-347x420.jpg 347w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-150x181.jpg 150w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-300x363.jpg 300w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-696x842.jpg 696w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-1068x1292.jpg 1068w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping-1920x2323.jpg 1920w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/amenable-to-exon-51-skipping.jpg 1984w\" sizes=\"(max-width: 847px) 100vw, 847px\" \/><figcaption class=\"wp-element-caption\"><a href=\"https:\/\/dmdwarrior.com\/hi\/mutations-and-deletions-amenable-to-exon-51-skipping-therapies-dmd\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u090f\u0915\u094d\u0938\u0949\u0928 51 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0925\u0947\u0930\u0947\u092a\u0940 \u0915\u0947 \u0905\u0928\u0941\u0915\u0942\u0932 \u0909\u0924\u094d\u092a\u0930\u093f\u0935\u0930\u094d\u0924\u0928 \u0914\u0930 \u0935\u093f\u0932\u094b\u092a\u0928<\/a><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0905\u092c \u0915\u094b\u0936\u093f\u0936 \u0915\u0930\u094b:<\/strong> <strong><a href=\"https:\/\/dmdwarrior.com\/hi\/duchenne-exon-deletion-tool\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0921\u0940\u090f\u092e\u0921\u0940 \u092f\u093e \u092c\u0940\u090f\u092e\u0921\u0940? \u090f\u0915\u094d\u0938\u0949\u0928 \u091a\u0947\u0915 \u091f\u0942\u0932<\/a><\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 id=\"how-the-forzetto-phase-3-trial-will-work\" class=\"wp-block-heading\">FORZETTO \u092b\u0947\u091c 3 \u091f\u094d\u0930\u093e\u092f\u0932 \u0915\u0948\u0938\u0947 \u0915\u093e\u092e \u0915\u0930\u0947\u0917\u093e<\/h2>\n\n\n\n<h3 id=\"global-randomized-placebo-controlled-study\" class=\"wp-block-heading\">\u0935\u0948\u0936\u094d\u0935\u093f\u0915 \u092f\u093e\u0926\u0943\u091a\u094d\u091b\u093f\u0915 \u092a\u094d\u0932\u0947\u0938\u0940\u092c\u094b-\u0928\u093f\u092f\u0902\u0924\u094d\u0930\u093f\u0924 \u0905\u0927\u094d\u092f\u092f\u0928<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>DYNE-251 \u092b\u0947\u091c 3 FORZETTO \u091f\u094d\u0930\u093e\u092f\u0932 \u090f\u0915 \u0935\u0948\u0936\u094d\u0935\u093f\u0915, \u092f\u093e\u0926\u0943\u091a\u094d\u091b\u093f\u0915, \u0921\u092c\u0932-\u092c\u094d\u0932\u093e\u0907\u0902\u0921, \u092a\u094d\u0932\u0947\u0938\u0940\u092c\u094b-\u0928\u093f\u092f\u0902\u0924\u094d\u0930\u093f\u0924 \u0905\u0927\u094d\u092f\u092f\u0928 \u0939\u0948 \u091c\u093f\u0938\u0947 \u091c\u0947\u0921-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0947\u0928 \u0915\u0940 \u0938\u0941\u0930\u0915\u094d\u0937\u093e \u0914\u0930 \u092a\u094d\u0930\u092d\u093e\u0935\u0936\u0940\u0932\u0924\u093e \u0915\u093e \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0921\u093f\u091c\u093c\u093e\u0907\u0928 \u0915\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948\u0964.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u0947 \u092a\u094d\u0930\u092e\u0941\u0916 \u0935\u093f\u0935\u0930\u0923\u094b\u0902 \u092e\u0947\u0902 \u0928\u093f\u092e\u094d\u0928\u0932\u093f\u0916\u093f\u0924 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0932\u0917\u092d\u0917 90 \u091a\u0932\u0928\u0947-\u092b\u093f\u0930\u0928\u0947 \u092e\u0947\u0902 \u0938\u0915\u094d\u0937\u092e \u092a\u0941\u0930\u0941\u0937 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u0940<\/li>\n\n\n\n<li>4 \u0938\u0947 18 \u0935\u0930\u094d\u0937 \u0915\u0940 \u0906\u092f\u0941 \u0915\u0947 \u092c\u091a\u094d\u091a\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f<\/li>\n\n\n\n<li>\u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0915\u094b \u090f\u0915\u094d\u0938\u0949\u0928 51 \u0915\u094b \u091b\u094b\u0921\u093c\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0924\u0948\u092f\u093e\u0930 \u0930\u0939\u0928\u093e \u091a\u093e\u0939\u093f\u090f\u0964<\/li>\n\n\n\n<li>\u092e\u0930\u0940\u091c\u094b\u0902 \u0915\u094b \u0928\u093f\u092e\u094d\u0928\u0932\u093f\u0916\u093f\u0924 \u092e\u0947\u0902 \u0938\u0947 \u0915\u094b\u0908 \u090f\u0915 \u0909\u092a\u091a\u093e\u0930 \u092e\u093f\u0932\u0947\u0917\u093e:\n<ul class=\"wp-block-list\">\n<li>20 \u092e\u093f\u0932\u0940\u0917\u094d\u0930\u093e\u092e\/\u0915\u093f\u0932\u094b\u0917\u094d\u0930\u093e\u092e \u091c\u0947\u0921-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0947\u0928<\/li>\n\n\n\n<li>\u092f\u093e \u092a\u094d\u0932\u0947\u0938\u0940\u092c\u094b<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>\u0909\u092a\u091a\u093e\u0930 \u092a\u094d\u0930\u0924\u094d\u092f\u0947\u0915 \u091a\u093e\u0930 \u0938\u092a\u094d\u0924\u093e\u0939 (Q4W) \u092e\u0947\u0902 \u0926\u093f\u092f\u093e \u091c\u093e\u090f\u0917\u093e\u0964<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u092a\u0939\u0932\u093e \u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u091f\u094d\u0930\u093e\u092f\u0932 \u0938\u094d\u0925\u0932 \u092a\u0939\u0932\u0947 \u0939\u0940 \u0938\u0915\u094d\u0930\u093f\u092f \u0939\u094b \u091a\u0941\u0915\u093e \u0939\u0948 \u0914\u0930 \u0928\u093e\u092e\u093e\u0902\u0915\u0928 \u0905\u092c \u0916\u0941\u0932\u093e \u0939\u0948\u0964.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 id=\"primary-endpoint-focuses-on-muscle-function\" class=\"wp-block-heading\">\u092a\u094d\u0930\u093e\u0925\u092e\u093f\u0915 \u0932\u0915\u094d\u0937\u094d\u092f \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u0947 \u0915\u093e\u0930\u094d\u092f \u092a\u0930 \u0915\u0947\u0902\u0926\u094d\u0930\u093f\u0924 \u0939\u0948\u0964<\/h2>\n\n\n\n<h3 id=\"rise-from-floor-velocity-will-be-measured\" class=\"wp-block-heading\">\u092b\u0930\u094d\u0936 \u0938\u0947 \u0909\u0920\u0928\u0947 \u0915\u0940 \u0917\u0924\u093f \u092e\u093e\u092a\u0940 \u091c\u093e\u090f\u0917\u0940<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0907\u0938 \u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u093e \u092e\u0941\u0916\u094d\u092f \u0909\u0926\u094d\u0926\u0947\u0936\u094d\u092f 73\u0935\u0947\u0902 \u0938\u092a\u094d\u0924\u093e\u0939 \u092e\u0947\u0902 \u092b\u0930\u094d\u0936 \u0938\u0947 \u0909\u0920\u0928\u0947 \u0915\u0940 \u0917\u0924\u093f (\u0906\u0930\u090f\u092b\u090f\u092b) \u092e\u0947\u0902 \u0939\u094b\u0928\u0947 \u0935\u093e\u0932\u0947 \u092a\u0930\u093f\u0935\u0930\u094d\u0924\u0928\u094b\u0902 \u0915\u094b \u092e\u093e\u092a\u0928\u093e \u0939\u0948, \u091c\u093f\u0938\u0947 \u0909\u0920\u0928\u0947 \u092e\u0947\u0902 \u0932\u0917\u0928\u0947 \u0935\u093e\u0932\u093e \u0938\u092e\u092f (\u091f\u0940\u091f\u0940\u0906\u0930) \u092d\u0940 \u0915\u0939\u093e \u091c\u093e\u0924\u093e \u0939\u0948\u0964.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u092f\u0939 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0907\u0938 \u092c\u093e\u0924 \u0915\u094b \u092e\u093e\u092a\u0924\u093e \u0939\u0948 \u0915\u093f \u0915\u094b\u0908 \u092e\u0930\u0940\u091c \u0915\u093f\u0924\u0928\u0940 \u091c\u0932\u094d\u0926\u0940 \u092b\u0930\u094d\u0936 \u0938\u0947 \u0916\u0921\u093c\u093e \u0939\u094b \u0938\u0915\u0924\u093e \u0939\u0948 \u0914\u0930 \u0907\u0938\u0947 \u0921\u0940\u090f\u092e\u0921\u0940 \u0915\u0947 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u092a\u0930\u0940\u0915\u094d\u0937\u0923\u094b\u0902 \u092e\u0947\u0902 \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u0940 \u0924\u093e\u0915\u0924 \u0914\u0930 \u092e\u094b\u091f\u0930 \u0938\u092e\u0928\u094d\u0935\u092f \u0915\u093e \u090f\u0915 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0938\u0902\u0915\u0947\u0924\u0915 \u092e\u093e\u0928\u093e \u091c\u093e\u0924\u093e \u0939\u0948\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0907\u0938\u0938\u0947 \u092a\u0939\u0932\u0947 \u0915\u0947 \u091a\u0930\u0923 1\/2 DELIVER \u0905\u0927\u094d\u092f\u092f\u0928 \u092e\u0947\u0902, z-rostudirsen \u0938\u0947 \u0909\u092a\u091a\u093e\u0930\u093f\u0924 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0928\u0947 \u092a\u094d\u0932\u0947\u0938\u0940\u092c\u094b \u0938\u0947 \u0909\u092a\u091a\u093e\u0930\u093f\u0924 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0915\u0940 \u0924\u0941\u0932\u0928\u093e \u092e\u0947\u0902 \u091b\u0939 \u092e\u0939\u0940\u0928\u0947 \u092c\u093e\u0926 RFF \u0935\u0947\u0917 \u092e\u0947\u0902 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0938\u0941\u0927\u093e\u0930 \u0926\u093f\u0916\u093e\u092f\u093e\u0964.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 id=\"additional-secondary-endpoints-in-the-forzetto-study\" class=\"wp-block-heading\">FORZETTO \u0905\u0927\u094d\u092f\u092f\u0928 \u092e\u0947\u0902 \u0905\u0924\u093f\u0930\u093f\u0915\u094d\u0924 \u0926\u094d\u0935\u093f\u0924\u0940\u092f\u0915 \u0932\u0915\u094d\u0937\u094d\u092f<\/h2>\n\n\n\n<h3 id=\"researchers-will-track-mobility-and-lung-function\" class=\"wp-block-heading\">\u0936\u094b\u0927\u0915\u0930\u094d\u0924\u093e \u0917\u0924\u093f\u0936\u0940\u0932\u0924\u093e \u0914\u0930 \u092b\u0947\u092b\u0921\u093c\u094b\u0902 \u0915\u0940 \u0915\u093e\u0930\u094d\u092f\u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u092a\u0930 \u0928\u091c\u093c\u0930 \u0930\u0916\u0947\u0902\u0917\u0947\u0964<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u0907\u0938 \u0905\u0927\u094d\u092f\u092f\u0928 \u092e\u0947\u0902 \u0915\u0908 \u0905\u0924\u093f\u0930\u093f\u0915\u094d\u0924 \u0915\u093e\u0930\u094d\u092f\u093e\u0924\u094d\u092e\u0915 \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u0915\u093e \u092d\u0940 \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u0915\u093f\u092f\u093e \u091c\u093e\u090f\u0917\u093e, \u091c\u093f\u0928\u092e\u0947\u0902 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0938\u094d\u091f\u094d\u0930\u093e\u0907\u0921 \u0935\u0947\u0932\u094b\u0938\u093f\u091f\u0940 95\u0935\u093e\u0902 \u092a\u0930\u0938\u0947\u0902\u091f\u093e\u0907\u0932 (SV95C)<\/li>\n\n\n\n<li><a href=\"https:\/\/dmdwarrior.com\/hi\/north-star-ambulatory-assessment-nsaa-in-duchenne-dmd\/\" target=\"_blank\" data-type=\"post\" data-id=\"4959\" rel=\"noreferrer noopener\">\u0928\u0949\u0930\u094d\u0925 \u0938\u094d\u091f\u093e\u0930 \u090f\u0902\u092c\u0941\u0932\u0947\u091f\u0930\u0940 \u0905\u0938\u0947\u0938\u092e\u0947\u0902\u091f (\u090f\u0928\u090f\u0938\u090f\u090f)<\/a><\/li>\n\n\n\n<li>10 \u092e\u0940\u091f\u0930 \u092a\u0948\u0926\u0932 \u091a\u0932\u0928\u093e\/\u0926\u094c\u0921\u093c\u0928\u093e (10MWR)<\/li>\n\n\n\n<li>\u091a\u093e\u0930 \u0938\u0940\u0922\u093c\u093f\u092f\u093e\u0901 \u091a\u0922\u093c\u0928\u093e (4SC)<\/li>\n\n\n\n<li>\u0905\u0928\u0941\u092e\u093e\u0928\u093f\u0924 \u092c\u093e\u0927\u094d\u092f \u091c\u0940\u0935\u0928 \u0915\u094d\u0937\u092e\u0924\u093e \u092a\u094d\u0930\u0924\u093f\u0936\u0924 (FVC%p)<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u0936\u094b\u0927\u0915\u0930\u094d\u0924\u093e \u092e\u0930\u0940\u091c\u094b\u0902 \u0926\u094d\u0935\u093e\u0930\u093e \u092c\u0924\u093e\u090f \u0917\u090f \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u0915\u094b \u092d\u0940 \u090f\u0915\u0924\u094d\u0930 \u0915\u0930\u0947\u0902\u0917\u0947 \u0924\u093e\u0915\u093f \u092f\u0939 \u092c\u0947\u0939\u0924\u0930 \u0922\u0902\u0917 \u0938\u0947 \u0938\u092e\u091d\u093e \u091c\u093e \u0938\u0915\u0947 \u0915\u093f \u0909\u092a\u091a\u093e\u0930 \u0926\u0948\u0928\u093f\u0915 \u091c\u0940\u0935\u0928 \u0915\u094b \u0915\u0948\u0938\u0947 \u092a\u094d\u0930\u092d\u093e\u0935\u093f\u0924 \u0915\u0930 \u0938\u0915\u0924\u093e \u0939\u0948\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u092a\u094d\u0930\u093e\u0930\u0902\u092d\u093f\u0915 72-\u0938\u092a\u094d\u0924\u093e\u0939 \u0915\u0940 \u092a\u094d\u0932\u0947\u0938\u0940\u092c\u094b-\u0928\u093f\u092f\u0902\u0924\u094d\u0930\u093f\u0924 \u0905\u0935\u0927\u093f \u0915\u0947 \u092c\u093e\u0926, \u092a\u093e\u0924\u094d\u0930 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u0940 96-\u0938\u092a\u094d\u0924\u093e\u0939 \u0915\u0947 \u0913\u092a\u0928-\u0932\u0947\u092c\u0932 \u090f\u0915\u094d\u0938\u091f\u0947\u0902\u0936\u0928 \u0905\u0927\u094d\u092f\u092f\u0928 \u092e\u0947\u0902 \u092d\u093e\u0917 \u0932\u0947 \u0938\u0915\u0924\u0947 \u0939\u0948\u0902\u0964.<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 id=\"fda-alignment-and-accelerated-approval-plans\" class=\"wp-block-heading\">FDA \u0938\u0902\u0930\u0947\u0916\u0923 \u0914\u0930 \u0924\u094d\u0935\u0930\u093f\u0924 \u0905\u0928\u0941\u092e\u094b\u0926\u0928 \u092f\u094b\u091c\u0928\u093e\u090f\u0901<\/h2>\n\n\n\n<h3 id=\"forzetto-could-support-full-traditional-approval\" class=\"wp-block-heading\">FORZETTO \u092a\u0942\u0930\u094d\u0923 \u092a\u093e\u0930\u0902\u092a\u0930\u093f\u0915 \u0905\u0928\u0941\u092e\u094b\u0926\u0928 \u0915\u093e \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930 \u0938\u0915\u0924\u093e \u0939\u0948<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Dyne Therapeutics \u0928\u0947 \u0915\u0939\u093e \u0915\u093f \u0915\u0902\u092a\u0928\u0940 \u0928\u0947 FORZETTO \u091a\u0930\u0923 3 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0921\u093f\u091c\u093e\u0907\u0928 \u0914\u0930 \u092a\u094d\u0930\u094b\u091f\u094b\u0915\u0949\u0932 \u092a\u0930 \u0905\u092e\u0947\u0930\u093f\u0915\u0940 \u0916\u093e\u0926\u094d\u092f \u090f\u0935\u0902 \u0914\u0937\u0927\u093f \u092a\u094d\u0930\u0936\u093e\u0938\u0928 (FDA) \u0915\u0947 \u0938\u093e\u0925 \u0938\u0939\u092e\u0924\u093f \u0935\u094d\u092f\u0915\u094d\u0924 \u0915\u0940 \u0939\u0948\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0907\u0938 \u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u093e \u0909\u0926\u094d\u0926\u0947\u0936\u094d\u092f \u0905\u092e\u0947\u0930\u093f\u0915\u093e \u092e\u0947\u0902 \u0924\u094d\u0935\u0930\u093f\u0924 \u0905\u0928\u0941\u092e\u094b\u0926\u0928 \u0915\u094b \u092a\u0942\u0930\u094d\u0923 \u092a\u093e\u0930\u0902\u092a\u0930\u093f\u0915 \u0905\u0928\u0941\u092e\u094b\u0926\u0928 \u092e\u0947\u0902 \u092a\u0930\u093f\u0935\u0930\u094d\u0924\u093f\u0924 \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0906\u0935\u0936\u094d\u092f\u0915 \u092a\u0941\u0937\u094d\u091f\u093f\u0915\u0930\u0923 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u0947 \u0930\u0942\u092a \u092e\u0947\u0902 \u0915\u093e\u0930\u094d\u092f \u0915\u0930\u0928\u093e \u0939\u0948\u0964 \u092f\u0939 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0905\u092e\u0947\u0930\u093f\u0915\u093e \u0915\u0947 \u092c\u093e\u0939\u0930 \u092d\u0935\u093f\u0937\u094d\u092f \u0915\u0947 \u0928\u093f\u092f\u093e\u092e\u0915 \u0906\u0935\u0947\u0926\u0928\u094b\u0902 \u0915\u093e \u092d\u0940 \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930 \u0938\u0915\u0924\u093e \u0939\u0948\u0964.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 id=\"why-the-dyne-therapeutics-phase-3-forzetto-trial-of-z-rostudirsen-for-dmd-matters\" class=\"wp-block-heading\">\u0921\u0940\u090f\u092e\u0921\u0940 \u0915\u0947 \u0932\u093f\u090f \u091c\u0947\u0921-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0947\u0928 \u0915\u0947 1\u091f\u0940\u092a\u094045\u091f\u0940 \u092b\u0947\u091c 3 1\u091f\u0940\u092a\u0940135\u091f\u0940 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u093e \u092e\u0939\u0924\u094d\u0935 \u0915\u094d\u092f\u094b\u0902 \u0939\u0948?<\/h2>\n\n\n\n<h3 id=\"a-potentially-important-development-for-the-dmd-community\" class=\"wp-block-heading\">\u0921\u0940\u090f\u092e\u0921\u0940 \u0938\u092e\u0941\u0926\u093e\u092f \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u0938\u0902\u092d\u093e\u0935\u093f\u0924 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0918\u091f\u0928\u093e\u0915\u094d\u0930\u092e<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0921\u0940\u090f\u092e\u0921\u0940 \u0915\u0947 \u0932\u093f\u090f \u091c\u0947\u0921-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0947\u0928 \u0915\u0947 1\u091f\u0940\u092a\u094045\u091f\u0940 \u092b\u0947\u091c 3 1\u091f\u0940\u092a\u0940135\u091f\u0940 \u091f\u094d\u0930\u093e\u092f\u0932 \u0915\u093e \u0936\u0941\u092d\u093e\u0930\u0902\u092d \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0938\u092e\u0941\u0926\u093e\u092f \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u092e\u0940\u0932 \u0915\u093e \u092a\u0924\u094d\u0925\u0930 \u0939\u0948, \u0935\u093f\u0936\u0947\u0937 \u0930\u0942\u092a \u0938\u0947 \u0909\u0928 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u091c\u094b \u090f\u0915\u094d\u0938\u0949\u0928 51 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0925\u0947\u0930\u0947\u092a\u0940 \u0915\u0947 \u0932\u093f\u090f \u092a\u093e\u0924\u094d\u0930 \u0939\u0948\u0902\u0964.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u092a\u0939\u0932\u0947 \u0915\u0947 \u0906\u0936\u093e\u091c\u0928\u0915 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u0906\u0902\u0915\u0921\u093c\u094b\u0902 \u0914\u0930 \u091a\u0932 \u0930\u0939\u0947 \u090f\u0915 \u092c\u0921\u093c\u0947 \u092a\u0941\u0937\u094d\u091f\u093f\u0915\u0930\u0923 \u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u0947 \u0938\u093e\u0925, \u0936\u094b\u0927\u0915\u0930\u094d\u0924\u093e \u0914\u0930 \u092a\u0930\u093f\u0935\u093e\u0930 \u0907\u0938 \u092c\u093e\u0924 \u092a\u0930 \u092c\u093e\u0930\u0940\u0915\u0940 \u0938\u0947 \u0928\u091c\u0930 \u0930\u0916\u0947\u0902\u0917\u0947 \u0915\u093f \u0915\u094d\u092f\u093e DYNE-251 \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u0938\u0947 \u092a\u0940\u0921\u093c\u093f\u0924 \u0932\u094b\u0917\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0938\u093e\u0930\u094d\u0925\u0915 \u0915\u093e\u0930\u094d\u092f\u093e\u0924\u094d\u092e\u0915 \u0938\u0941\u0927\u093e\u0930 \u0932\u093e \u0938\u0915\u0924\u093e \u0939\u0948\u0964.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 id=\"contact-information\" class=\"wp-block-heading\">\u0938\u0902\u092a\u0930\u094d\u0915 \u091c\u093e\u0928\u0915\u093e\u0930\u0940<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0928\u093e\u092e: \u0921\u093e\u092f\u0928 \u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u091f\u094d\u0930\u093e\u092f\u0932\u094d\u0938<\/li>\n\n\n\n<li>\u092b\u093c\u094b\u0928 \u0928\u0902\u092c\u0930: +1-781-317-1919<\/li>\n\n\n\n<li>\u0908\u092e\u0947\u0932: clinicaltrials@dyne-tx.com<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0907\u0938 \u092a\u0947\u091c \u0915\u094b \u092b\u093c\u0949\u0932\u094b \u0915\u0930\u0947\u0902<\/strong>&nbsp;&gt;&gt;&gt;&nbsp;<a href=\"https:\/\/dmdwarrior.com\/hi\/dmd-therapies\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0915\u0947 \u0932\u093f\u090f \u0938\u092d\u0940 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u092a\u0930\u0940\u0915\u094d\u0937\u0923<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Dyne Therapeutics has announced the start of the Dyne Therapeutics Phase 3 FORZETTO Trial (NCT07608432) of Z-Rostudirsen for DMD, marking another major step forward for families affected by Duchenne muscular dystrophy (DMD). The global Phase 3 study will evaluate z-rostudirsen (DYNE-251) in people living with DMD who are amenable to exon 51 skipping. The company [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":8013,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[137,143,208,145,122,193,421,194,780,460],"class_list":["post-7974","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-clinical-trial","tag-dyne","tag-dyne-therapeutics","tag-dyne-251","tag-exon-51","tag-exon-51-skipping","tag-exon-51-skipping-therapy","tag-exon-51-treatment","tag-forzetto","tag-z-rostudirsen"],"subtitle":"Dyne Therapeutics \u0928\u0947 \u090f\u0915\u094d\u0938\u0949\u0928 51 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0915\u0947 \u0932\u093f\u090f \u092a\u093e\u0924\u094d\u0930 \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 (DMD) \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f DYNE-251 (NCT07608432) \u0915\u0947 \u0924\u0940\u0938\u0930\u0947 \u091a\u0930\u0923 \u0915\u0947 FORZETTO \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u0940 \u0936\u0941\u0930\u0941\u0906\u0924 \u0915\u0940 \u0939\u0948\u0964 \u092f\u0939 \u0935\u0948\u0936\u094d\u0935\u093f\u0915 \u0905\u0927\u094d\u092f\u092f\u0928 \u091c\u093c\u0947\u0921-\u0930\u094b\u0938\u094d\u091f\u0941\u0921\u093f\u0930\u0938\u0947\u0928 \u0915\u094b FDA \u0915\u0940 \u092e\u0902\u091c\u0942\u0930\u0940 \u0915\u0947 \u0915\u0930\u0940\u092c \u0932\u093e \u0938\u0915\u0924\u093e \u0939\u0948 \u0914\u0930 DMD \u0938\u092e\u0941\u0926\u093e\u092f \u092e\u0947\u0902 \u0928\u0908 \u0909\u092e\u094d\u092e\u0940\u0926 \u091c\u0917\u093e \u0938\u0915\u0924\u093e \u0939\u0948\u0964.","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/7974","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/comments?post=7974"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/7974\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media\/8013"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media?parent=7974"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/categories?post=7974"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/tags?post=7974"}],"curies":[{"name":"\u0921\u092c\u094d\u0932\u094d\u092f\u0942\u092a\u0940","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}