{"id":5285,"date":"2025-12-03T17:41:43","date_gmt":"2025-12-03T14:41:43","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=5285"},"modified":"2025-12-03T17:52:01","modified_gmt":"2025-12-03T14:52:01","slug":"capricor-therapeutics-announces-positive-topline-results","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/hi\/capricor-therapeutics-announces-positive-topline-results\/","title":{"rendered":"Capricor Therapeutics \u0928\u0947 \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u092e\u0947\u0902 Deramiocel \u0915\u0947 \u0928\u093f\u0930\u094d\u0923\u093e\u092f\u0915 \u091a\u0930\u0923 3 HOPE-3 \u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u0947 \u0938\u0915\u093e\u0930\u093e\u0924\u094d\u092e\u0915 \u0936\u0940\u0930\u094d\u0937 \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u0915\u0940 \u0918\u094b\u0937\u0923\u093e \u0915\u0940"},"content":{"rendered":"

\u0939\u094b\u092a-3 \u090f\u0915 \u092f\u093e\u0926\u0943\u091a\u094d\u091b\u093f\u0915, \u0921\u092c\u0932-\u092c\u094d\u0932\u093e\u0907\u0902\u0921, \u092a\u094d\u0932\u0947\u0938\u0940\u092c\u094b-\u0928\u093f\u092f\u0902\u0924\u094d\u0930\u093f\u0924, \u091a\u0930\u0923 3 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0939\u0948 \u091c\u094b \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u0938\u0947 \u092a\u0940\u0921\u093c\u093f\u0924 \u0932\u0921\u093c\u0915\u094b\u0902 \u0914\u0930 \u092f\u0941\u0935\u093e \u092a\u0941\u0930\u0941\u0937\u094b\u0902 \u092e\u0947\u0902 Deramiocel \u0915\u093e \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u0915\u0930\u0924\u093e \u0939\u0948\u0964 \u0907\u0938 \u0905\u0927\u094d\u092f\u092f\u0928 \u092e\u0947\u0902 \u0905\u092e\u0947\u0930\u093f\u0915\u093e \u0915\u0947 20 \u092a\u094d\u0930\u092e\u0941\u0916 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u0915\u0947\u0902\u0926\u094d\u0930\u094b\u0902 \u092e\u0947\u0902 106 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0915\u094b \u092f\u093e\u0926\u0943\u091a\u094d\u091b\u093f\u0915 \u0930\u0942\u092a \u0938\u0947 \u0936\u093e\u092e\u093f\u0932 \u0915\u093f\u092f\u093e \u0917\u092f\u093e\u0964 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0915\u094b 12 \u092e\u0939\u0940\u0928\u0947 \u0915\u0940 \u0905\u0935\u0927\u093f \u0915\u0947 \u0932\u093f\u090f \u0939\u0930 \u0924\u0940\u0928 \u092e\u0939\u0940\u0928\u0947 \u092e\u0947\u0902 15 \u0915\u0930\u094b\u0921\u093c \u0915\u094b\u0936\u093f\u0915\u093e\u0913\u0902 \u0915\u0947 \u0907\u0902\u091c\u0947\u0915\u094d\u0936\u0928 \u092f\u093e \u092a\u094d\u0932\u0947\u0938\u0940\u092c\u094b \u0915\u0947 \u092e\u093e\u0927\u094d\u092f\u092e \u0938\u0947 Deramiocel \u0926\u093f\u092f\u093e \u0917\u092f\u093e\u0964.<\/p>\n\n\n\n

\u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0915\u0940 \u0914\u0938\u0924 \u0906\u092f\u0941 \u0932\u0917\u092d\u0917 15 \u0935\u0930\u094d\u0937 \u0925\u0940, \u0914\u0930 \u0938\u092d\u0940 \u092a\u0942\u0930\u0947 \u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u0947 \u0926\u094c\u0930\u093e\u0928 \u0938\u094d\u0925\u093f\u0930 \u0915\u0949\u0930\u094d\u091f\u093f\u0915\u094b\u0938\u094d\u091f\u0947\u0930\u0949\u0907\u0921 \u0909\u092a\u091a\u093e\u0930 \u092a\u0930 \u0925\u0947\u0964 \u0909\u092a\u091a\u093e\u0930 \u0938\u092e\u0942\u0939\u094b\u0902 \u0915\u0947 \u092c\u0940\u091a \u0906\u0927\u093e\u0930\u092d\u0942\u0924 \u091c\u0928\u0938\u093e\u0902\u0916\u094d\u092f\u093f\u0915\u0940 \u0905\u091a\u094d\u091b\u0940 \u0924\u0930\u0939 \u0938\u0947 \u0938\u0902\u0924\u0941\u0932\u093f\u0924 \u0925\u0940, \u0932\u0917\u092d\u0917 90 \u092a\u094d\u0930\u0924\u093f\u0936\u0924 \u0932\u094b\u0917 \u0906\u0927\u093e\u0930\u092d\u0942\u0924 \u0938\u094d\u0924\u0930 \u092a\u0930 \u0939\u0943\u0926\u092f \u0938\u0902\u092c\u0902\u0927\u0940 \u0926\u0935\u093e\u090f\u0901 \u0932\u0947 \u0930\u0939\u0947 \u0925\u0947, \u0914\u0930 75 \u092a\u094d\u0930\u0924\u093f\u0936\u0924 \u0938\u0947 \u0905\u0927\u093f\u0915 \u0932\u094b\u0917\u094b\u0902 \u092e\u0947\u0902 \u0915\u093e\u0930\u094d\u0921\u093f\u092f\u094b\u092e\u093e\u092f\u094b\u092a\u0948\u0925\u0940 \u0915\u093e \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u0928\u093f\u0926\u093e\u0928 \u0925\u093e\u0964 Deramiocel \u0928\u0947 \u092a\u0942\u0930\u094d\u0935 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u0905\u0928\u0941\u092d\u0935 \u0915\u0947 \u0905\u0928\u0941\u0930\u0942\u092a \u090f\u0915 \u0905\u0928\u0941\u0915\u0942\u0932 \u0938\u0941\u0930\u0915\u094d\u0937\u093e \u0914\u0930 \u0938\u0939\u0928\u0936\u0940\u0932\u0924\u093e \u092a\u094d\u0930\u094b\u092b\u093c\u093e\u0907\u0932 \u092c\u0928\u093e\u090f \u0930\u0916\u0940\u0964 >>>\u00a0Deramiocel \u0915\u094d\u092f\u093e \u0939\u0948? CAP-1002 \u0915\u094d\u092f\u093e \u0915\u0930\u0924\u093e \u0939\u0948?<\/a><\/p>\n\n\n\n

\u0936\u0940\u0930\u094d\u0937 \u092a\u094d\u0930\u092d\u093e\u0935\u0915\u093e\u0930\u093f\u0924\u093e \u092a\u0930\u093f\u0923\u093e\u092e<\/h2>\n\n\n\n
endpoint<\/strong><\/td>% \u092a\u094d\u0930\u0917\u0924\u093f \u0915\u093e \u0927\u0940\u092e\u093e \u0939\u094b\u0928\u093e<\/strong>3<\/strong><\/sup>
(Deramiocel \u092c\u0928\u093e\u092e \u092a\u094d\u0932\u0947\u0938\u0940\u092c\u094b)<\/strong><\/td>		\u092a\u0940-\u092e\u093e\u0928<\/strong><\/td><\/tr>
\u090a\u092a\u0930\u0940 \u0905\u0902\u0917 \u0915\u093e \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u0928 (PUL v2.0) \u0915\u0941\u0932 \u0938\u094d\u0915\u094b\u0930<\/strong>\u00b9
(\u092a\u094d\u0930\u093e\u0925\u092e\u093f\u0915, n=105)<\/td>		54%<\/td>\u092a\u0940=0.029<\/td><\/tr>
\u092c\u093e\u090f\u0902 \u0935\u0947\u0902\u091f\u094d\u0930\u093f\u0915\u0941\u0932\u0930 \u0907\u091c\u0947\u0915\u094d\u0936\u0928 \u0905\u0902\u0936 (LVEF %)<\/strong>\u00b2
(\u092e\u0941\u0916\u094d\u092f \u0926\u094d\u0935\u093f\u0924\u0940\u092f\u0915, n=83)<\/td>		91%<\/td>\u092a\u0940=0.041<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u00b9 n 12 \u092e\u0939\u0940\u0928\u094b\u0902 \u092e\u0947\u0902 \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u092f\u094b\u0917\u094d\u092f PUL v2.0 \u0906\u0915\u0932\u0928 \u0915\u0947 \u0938\u093e\u0925 ITT \u0906\u092c\u093e\u0926\u0940 \u092e\u0947\u0902 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u0940 \u0938\u0902\u0916\u094d\u092f\u093e \u0915\u094b \u0926\u0930\u094d\u0936\u093e\u0924\u093e \u0939\u0948\u0964.
\u00b2 n 12 \u092e\u0939\u0940\u0928\u094b\u0902 \u092e\u0947\u0902 \u0915\u0947\u0902\u0926\u094d\u0930\u0940\u092f \u0930\u0942\u092a \u0938\u0947 \u0938\u092e\u0940\u0915\u094d\u0937\u093f\u0924 \u0914\u0930 \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u092f\u094b\u0917\u094d\u092f \u0915\u093e\u0930\u094d\u0921\u093f\u092f\u0915 \u090f\u092e\u0906\u0930\u0906\u0908 \u090f\u0932\u0935\u0940\u0908\u090f\u092b \u0906\u0915\u0932\u0928 \u0915\u0947 \u0938\u093e\u0925 \u0906\u0908\u091f\u0940\u091f\u0940 \u0906\u092c\u093e\u0926\u0940 \u092e\u0947\u0902 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u0940 \u0938\u0902\u0916\u094d\u092f\u093e \u0915\u094b \u0926\u0930\u094d\u0936\u093e\u0924\u093e \u0939\u0948\u0964.
3 <\/sup>\u092a\u094d\u0930\u0924\u093f\u0936\u0924 \u0927\u0940\u092e\u093e\u092a\u0928 \u0915\u0940 \u0917\u0923\u0928\u093e \u0909\u092a\u091a\u093e\u0930 \u0905\u0902\u0924\u0930 \u0915\u094b \u0906\u0927\u093e\u0930 \u0930\u0947\u0916\u093e \u0938\u0947 \u092a\u094d\u0932\u0947\u0938\u0940\u092c\u094b \u092a\u0930\u093f\u0935\u0930\u094d\u0924\u0928 \u0938\u0947 \u0935\u093f\u092d\u093e\u091c\u093f\u0924 \u0915\u0930\u0915\u0947 \u0915\u0940 \u091c\u093e\u0924\u0940 \u0939\u0948\u0964.<\/p>\n\n\n\n

\u0907\u0938 \u092a\u0947\u091c \u0915\u094b \u092b\u093c\u0949\u0932\u094b \u0915\u0930\u0947\u0902<\/strong> >>> \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0915\u0947 \u0932\u093f\u090f \u0938\u092d\u0940 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u092a\u0930\u0940\u0915\u094d\u0937\u0923<\/a><\/p>","protected":false},"excerpt":{"rendered":"

HOPE-3 is a randomized, double-blind, placebo-controlled, Phase 3 clinical trial evaluating Deramiocel in boys and young men with Duchenne muscular dystrophy. The study randomized 106 participants across 20 leading U.S. clinical sites. Participants received intravenous Deramiocel at 150 million cells per infusion or placebo every three months for a 12-month period. The average age of […]<\/p>\n","protected":false},"author":1,"featured_media":5287,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[86,87,303,137,85],"class_list":["post-5285","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-capricor","tag-capricor-therapeutics","tag-cell-therapy","tag-clinical-trial","tag-deramiocel"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/5285","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/comments?post=5285"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/5285\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media\/5287"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media?parent=5285"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/categories?post=5285"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/tags?post=5285"}],"curies":[{"name":"\u0921\u092c\u094d\u0932\u094d\u092f\u0942\u092a\u0940","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}