{"id":5183,"date":"2025-11-19T18:44:39","date_gmt":"2025-11-19T15:44:39","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=5183"},"modified":"2025-11-19T19:06:37","modified_gmt":"2025-11-19T16:06:37","slug":"avidity-biosciences-announces-u-s-managed-access-program-map-for-investigational-therapy-del-zota-in-dmd44","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/hi\/avidity-biosciences-announces-u-s-managed-access-program-map-for-investigational-therapy-del-zota-in-dmd44\/","title":{"rendered":"Avidity Biosciences \u0928\u0947 \u091c\u093e\u0902\u091a \u091a\u093f\u0915\u093f\u0924\u094d\u0938\u093e del-zota (\u090f\u0915\u094d\u0938\u0949\u0928 44 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917) \u0915\u0947 \u0932\u093f\u090f \u0905\u092e\u0947\u0930\u093f\u0915\u0940 \u092a\u094d\u0930\u092c\u0902\u0927\u093f\u0924 \u092a\u0939\u0941\u0902\u091a \u0915\u093e\u0930\u094d\u092f\u0915\u094d\u0930\u092e (MAP) \u0915\u0940 \u0918\u094b\u0937\u0923\u093e \u0915\u0940"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Avidity Biosciences \u0928\u0947 \u0938\u0902\u092f\u0941\u0915\u094d\u0924 \u0930\u093e\u091c\u094d\u092f \u0905\u092e\u0947\u0930\u093f\u0915\u093e \u092e\u0947\u0902 \u090f\u0915\u094d\u0938\u0949\u0928 44 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 (DMD44) \u0915\u0947 \u0932\u093f\u090f \u0909\u0924\u094d\u0924\u0930\u0926\u093e\u092f\u0940 \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u0909\u0924\u094d\u092a\u0930\u093f\u0935\u0930\u094d\u0924\u0928 \u0935\u093e\u0932\u0947 \u092a\u093e\u0924\u094d\u0930 \u0932\u094b\u0917\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u091c\u093e\u0902\u091a \u091a\u093f\u0915\u093f\u0924\u094d\u0938\u093e \u0921\u0947\u0932\u094d\u092a\u0947\u0938\u0940\u092c\u093e\u0930\u094d\u091f \u091c\u093c\u094b\u091f\u093e\u0921\u093f\u0930\u0938\u0947\u0928 (del-zota) \u0915\u0947 \u0932\u093f\u090f \u0905\u092a\u0928\u0947 \u092a\u094d\u0930\u092c\u0902\u0927\u093f\u0924 \u090f\u0915\u094d\u0938\u0947\u0938 \u092a\u094d\u0930\u094b\u0917\u094d\u0930\u093e\u092e (MAP) \u0915\u0940 \u0918\u094b\u0937\u0923\u093e \u0915\u0940\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201c\u090f\u0935\u093f\u0921\u093f\u091f\u0940 \u0915\u0940 \u0905\u0927\u094d\u092f\u0915\u094d\u0937 \u0914\u0930 \u092e\u0941\u0916\u094d\u092f \u0915\u093e\u0930\u094d\u092f\u0915\u093e\u0930\u0940 \u0905\u0927\u093f\u0915\u093e\u0930\u0940 \u0938\u093e\u0930\u093e \u092c\u0949\u092f\u0938 \u0928\u0947 \u0915\u0939\u093e, &quot;\u0939\u092e \u0921\u0940\u090f\u092e\u0921\u094044 \u0938\u092e\u0941\u0926\u093e\u092f \u0915\u0947 \u0938\u093e\u092e\u0928\u0947 \u092e\u094c\u091c\u0942\u0926 \u0935\u094d\u092f\u093e\u092a\u0915 \u091c\u093c\u0930\u0942\u0930\u0924\u094b\u0902 \u0915\u094b \u0938\u092e\u091d\u0924\u0947 \u0939\u0948\u0902, \u0915\u094d\u092f\u094b\u0902\u0915\u093f \u0907\u0938 \u092c\u0940\u092e\u093e\u0930\u0940 \u0915\u0947 \u0932\u093f\u090f \u0915\u094b\u0908 \u0938\u094d\u0935\u0940\u0915\u0943\u0924 \u090f\u0915\u094d\u0938\u0949\u0928 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0925\u0947\u0930\u0947\u092a\u0940 \u0909\u092a\u0932\u092c\u094d\u0927 \u0928\u0939\u0940\u0902 \u0939\u0948, \u0914\u0930 \u0939\u092e\u093e\u0930\u0947 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u0905\u0927\u094d\u092f\u092f\u0928\u094b\u0902 \u092e\u0947\u0902 \u0926\u093f\u0916\u093e\u090f \u0917\u090f \u0905\u092d\u0942\u0924\u092a\u0942\u0930\u094d\u0935 \u0906\u0902\u0915\u0921\u093c\u094b\u0902 \u0915\u0947 \u0906\u0927\u093e\u0930 \u092a\u0930 del-zota \u0915\u0940 \u0915\u094d\u0937\u092e\u0924\u093e \u092d\u0940 \u0939\u0948\u0964&quot; \u0909\u0928\u094d\u0939\u094b\u0902\u0928\u0947 \u0906\u0917\u0947 \u0915\u0939\u093e, &quot;\u0939\u092e\u0947\u0902 \u092f\u094b\u0917\u094d\u092f \u092e\u0930\u0940\u091c\u093c\u094b\u0902 \u0915\u094b \u091c\u0932\u094d\u0926 \u0938\u0947 \u091c\u0932\u094d\u0926 del-zota \u0909\u092a\u0932\u092c\u094d\u0927 \u0915\u0930\u093e\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u0905\u0928\u0941\u092a\u093e\u0932\u0928 \u0926\u0943\u0937\u094d\u091f\u093f\u0915\u094b\u0923 \u0915\u094b \u0938\u0915\u094d\u0937\u092e \u0915\u0930\u0928\u0947 \u0939\u0947\u0924\u0941 \u0907\u0938 \u090f\u092e\u090f\u092a\u0940 \u0915\u094b \u0936\u0941\u0930\u0942 \u0915\u0930\u0924\u0947 \u0939\u0941\u090f \u0916\u0941\u0936\u0940 \u0939\u094b \u0930\u0939\u0940 \u0939\u0948\u0964&quot;\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">FDA-\u0905\u0927\u093f\u0915\u0943\u0924 \u0909\u092a\u091a\u093e\u0930 \u092a\u094d\u0930\u094b\u091f\u094b\u0915\u0949\u0932 \u0915\u0947 \u0924\u0939\u0924, \u090f\u0935\u093f\u0921\u093f\u091f\u0940 \u0921\u0940\u090f\u092e\u0921\u094044 \u0938\u0947 \u092a\u0940\u0921\u093c\u093f\u0924 \u092a\u093e\u0924\u094d\u0930 \u0932\u0921\u093c\u0915\u094b\u0902 \u0914\u0930 \u092a\u0941\u0930\u0941\u0937\u094b\u0902 \u0915\u094b \u0938\u0939\u092d\u093e\u0917\u0940 \u0938\u094d\u0935\u093e\u0938\u094d\u0925\u094d\u092f \u0938\u0947\u0935\u093e \u092a\u094d\u0930\u0926\u093e\u0924\u093e\u0913\u0902 \u0915\u0947 \u092e\u093e\u0927\u094d\u092f\u092e \u0938\u0947 del-zota \u092a\u094d\u0930\u0926\u093e\u0928 \u0915\u0930\u0947\u0917\u0940\u0964 \u0928\u093e\u092e\u093e\u0902\u0915\u0928 \u0935\u0930\u094d\u0937 \u0915\u0947 \u0905\u0902\u0924 \u0924\u0915 \u0936\u0941\u0930\u0942 \u0939\u094b\u0928\u0947 \u0915\u0940 \u0909\u092e\u094d\u092e\u0940\u0926 \u0939\u0948, \u0914\u0930 EXPLORE44-OLE \u0915\u0947 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0915\u0947 \u092a\u093e\u0938 2 \u0938\u093e\u0932 \u0915\u093e \u0909\u092a\u091a\u093e\u0930 \u092a\u0942\u0930\u093e \u0915\u0930\u0928\u0947 \u0915\u0947 \u092c\u093e\u0926 MAP \u092e\u0947\u0902 \u0938\u0902\u0915\u094d\u0930\u092e\u0923 \u0915\u093e \u0935\u093f\u0915\u0932\u094d\u092a \u0939\u094b\u0917\u093e\u0964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0905\u092c \u091c\u093e\u0902\u091a\u0947\u0902<\/strong>: <a href=\"https:\/\/dmdwarrior.com\/hi\/mutations-and-deletions-amenable-to-exon-44-skipping-therapies-dmd\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0915\u094d\u092f\u093e \u092e\u0947\u0930\u093e \u092c\u0947\u091f\u093e \u090f\u0915\u094d\u0938\u0949\u0928 44 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0925\u0947\u0930\u0947\u092a\u0940 \u0915\u0947 \u0932\u093f\u090f \u0909\u092e\u094d\u092e\u0940\u0926\u0935\u093e\u0930 \u0939\u0948?<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u090f\u0935\u093f\u0921\u093f\u091f\u0940 \u0928\u0947 FDA \u0915\u0947 \u0938\u093e\u0925 \u092e\u093f\u0932\u0915\u0930 del-zota \u0915\u0947 \u0932\u093f\u090f BLA \u0938\u092c\u092e\u093f\u0936\u0928 \u0915\u0940 \u0926\u093f\u0936\u093e \u092e\u0947\u0902 \u0915\u093e\u092e \u0915\u093f\u092f\u093e \u0939\u0948, \u091c\u093f\u0938\u0915\u0947 \u092c\u093e\u0926 \u0905\u0915\u094d\u091f\u0942\u092c\u0930 2025 \u092e\u0947\u0902 \u0939\u094b\u0928\u0947 \u0935\u093e\u0932\u0940 \u092a\u094d\u0930\u0940-BLA \u092e\u0940\u091f\u093f\u0902\u0917 \u0939\u094b\u0917\u0940\u0964 \u0907\u0938\u0947 \u0924\u094d\u0935\u0930\u093f\u0924 \u0905\u0928\u0941\u092e\u094b\u0926\u0928 \u0915\u0947 \u0932\u093f\u090f 2026 \u092e\u0947\u0902 \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924 \u0915\u0930\u0928\u0947 \u0915\u0940 \u092f\u094b\u091c\u0928\u093e \u0939\u0948\u0964 \u092d\u0935\u093f\u0937\u094d\u092f \u092e\u0947\u0902 \u0938\u0902\u092d\u093e\u0935\u093f\u0924 FDA \u0905\u0928\u0941\u092e\u094b\u0926\u0928 \u0914\u0930 \u0909\u0924\u094d\u092a\u093e\u0926 \u0909\u092a\u0932\u092c\u094d\u0927\u0924\u093e \u0915\u0947 \u0906\u0927\u093e\u0930 \u092a\u0930 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u0940 \u0935\u094d\u092f\u093e\u0935\u0938\u093e\u092f\u093f\u0915 \u0926\u0935\u093e \u0906\u092a\u0942\u0930\u094d\u0924\u093f \u092e\u0947\u0902 \u092c\u0926\u0932\u093e\u0935 \u0915\u0930\u0947\u0902\u0917\u0947\u0964.<a href=\"https:\/\/investors.aviditybiosciences.com\/2025-11-19-Avidity-Biosciences-Announces-U-S-Managed-Access-Program-MAP-for-Investigational-Therapy-del-zota-in-DMD44#print\" target=\"_blank\" rel=\"noopener\"><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0907\u0938 \u092a\u0947\u091c \u0915\u094b \u092b\u093c\u0949\u0932\u094b \u0915\u0930\u0947\u0902<\/strong>&nbsp;&gt;&gt;&gt;&nbsp;<a href=\"https:\/\/dmdwarrior.com\/hi\/dmd-therapies\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u0915\u0947 \u0932\u093f\u090f \u0938\u092d\u0940 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u092a\u0930\u0940\u0915\u094d\u0937\u0923<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Avidity Biosciences announced its Managed Access Program (MAP) for investigational therapy delpacibart zotadirsen (del-zota) for eligible people with Duchenne muscular dystrophy mutations amenable to exon 44 skipping (DMD44) in the United States. &#8220;We recognize the considerable needs facing the DMD44 community given there are no approved exon skipping therapies for this disease as well as [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":5185,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[126,298,397,129,141,127,246],"class_list":["post-5183","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-avidity-biosciences","tag-del-zota","tag-delpacibart-zotadirsen","tag-dmd44","tag-exon-44","tag-exon-44-skipping","tag-exon-44-skipping-therapies"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/5183","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/comments?post=5183"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/5183\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media\/5185"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media?parent=5183"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/categories?post=5183"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/tags?post=5183"}],"curies":[{"name":"\u0921\u092c\u094d\u0932\u094d\u092f\u0942\u092a\u0940","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}