{"id":3307,"date":"2025-03-19T19:20:55","date_gmt":"2025-03-19T16:20:55","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=3307"},"modified":"2025-03-19T19:20:57","modified_gmt":"2025-03-19T16:20:57","slug":"regenxbio-reports-positive-biomarker-data-from-affinity-duchenne-trial-of-rgx-202-gene-therapy","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/hi\/regenxbio-reports-positive-biomarker-data-from-affinity-duchenne-trial-of-rgx-202-gene-therapy\/","title":{"rendered":"Regenxbio \u0928\u0947 \u0906\u0930\u091c\u0940\u090f\u0915\u094d\u0938-202 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0915\u0947 \u090f\u092b\u093f\u0928\u093f\u091f\u0940 \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0938\u0947 \u0938\u0915\u093e\u0930\u093e\u0924\u094d\u092e\u0915 \u092c\u093e\u092f\u094b\u092e\u093e\u0930\u094d\u0915\u0930 \u0921\u0947\u091f\u093e \u0915\u0940 \u0930\u093f\u092a\u094b\u0930\u094d\u091f \u0915\u0940"},"content":{"rendered":"<p class=\"wp-block-paragraph\">REGENXBIO \u0928\u0947 RGX-202 \u0915\u0947 AFFINITY DUCHENNE\u00ae \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u0947 \u091a\u0930\u0923 I\/II \u092d\u093e\u0917 \u092e\u0947\u0902 \u0926\u094b \u0905\u0924\u093f\u0930\u093f\u0915\u094d\u0924 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0938\u0947 \u0928\u090f, \u0938\u0915\u093e\u0930\u093e\u0924\u094d\u092e\u0915 \u0905\u0902\u0924\u0930\u093f\u092e \u0921\u0947\u091f\u093e \u0915\u0940 \u0930\u093f\u092a\u094b\u0930\u094d\u091f \u0915\u0940, \u091c\u094b \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 (\u0921\u094d\u092f\u0942\u091a\u0947\u0928) \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u0935\u093f\u092d\u0947\u0926\u093f\u0924 \u091c\u093e\u0902\u091a \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0939\u0948\u0964 \u092a\u0930\u093f\u0923\u093e\u092e 2025 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u090f\u0938\u094b\u0938\u093f\u090f\u0936\u0928 (MDA) \u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u0914\u0930 \u0935\u0948\u091c\u094d\u091e\u093e\u0928\u093f\u0915 \u0938\u092e\u094d\u092e\u0947\u0932\u0928 \u092e\u0947\u0902 \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924 \u0915\u093f\u090f \u0917\u090f\u0964<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0906\u0930\u091c\u0940\u090f\u0915\u094d\u0938-202 \u0938\u0947 \u092a\u094d\u0930\u093e\u092a\u094d\u0924 \u092a\u094d\u0930\u092e\u0941\u0916 \u0928\u093f\u0937\u094d\u0915\u0930\u094d\u0937\u094b\u0902 \u092e\u0947\u0902 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0906\u0930\u091c\u0940\u090f\u0915\u094d\u0938-202 \u0915\u0940 \u0928\u093f\u0930\u094d\u0923\u093e\u092f\u0915 \u0916\u0941\u0930\u093e\u0915 \u092a\u094d\u0930\u093e\u092a\u094d\u0924 \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u0947 \u0926\u094b \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0938\u0947 \u092a\u094d\u0930\u093e\u092a\u094d\u0924 \u0928\u090f \u092c\u093e\u092f\u094b\u092e\u093e\u0930\u094d\u0915\u0930 \u0921\u0947\u091f\u093e \u0915\u094b \u090f\u092e\u0921\u0940\u090f \u092e\u0947\u0902 \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924 \u0915\u093f\u092f\u093e \u0917\u092f\u093e, \u0924\u0925\u093e \u092f\u0939 \u0938\u092d\u0940 \u0906\u092f\u0941 \u0935\u0930\u094d\u0917\u094b\u0902 \u092e\u0947\u0902 \u0906\u0930\u091c\u0940\u090f\u0915\u094d\u0938-202 \u092e\u093e\u0907\u0915\u094d\u0930\u094b\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u0940 \u0938\u0941\u0938\u0902\u0917\u0924, \u0938\u0941\u0926\u0943\u0922\u093c \u0905\u092d\u093f\u0935\u094d\u092f\u0915\u094d\u0924\u093f \u0914\u0930 \u0938\u0902\u091a\u0930\u0923 \u0915\u093e \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0924\u093e \u0939\u0948\u0964<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0916\u0941\u0930\u093e\u0915 \u0915\u0947 \u0938\u092e\u092f 3 \u0935\u0930\u094d\u0937 \u0915\u0940 \u0906\u092f\u0941 \u0915\u0947 \u090f\u0915 \u0930\u094b\u0917\u0940 \u092e\u0947\u0902, \u092e\u093e\u0907\u0915\u094d\u0930\u094b\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0905\u092d\u093f\u0935\u094d\u092f\u0915\u094d\u0924\u093f \u0915\u094b \u0928\u093f\u092f\u0902\u0924\u094d\u0930\u0923 \u0915\u0940 \u0924\u0941\u0932\u0928\u093e \u092e\u0947\u0902 122.3% \u092e\u093e\u092a\u093e \u0917\u092f\u093e\u0964 4 \u0935\u0930\u094d\u0937 \u0938\u0947 \u0915\u092e \u0906\u092f\u0941 \u0915\u0947 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u0947 \u092a\u093e\u0938 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0924\u0915 \u092a\u0939\u0941\u0902\u091a \u0928\u0939\u0940\u0902 \u0939\u0948, \u0914\u0930 REGENXBIO \u0905\u092e\u0947\u0930\u093f\u0915\u093e \u092e\u0947\u0902 \u0907\u0938 \u0906\u092f\u0941 \u0935\u0930\u094d\u0917 \u0915\u0947 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u094b \u092d\u0930\u094d\u0924\u0940 \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u093e \u090f\u0915\u092e\u093e\u0924\u094d\u0930 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u092a\u094d\u0930\u093e\u092f\u094b\u091c\u0915 \u0939\u0948<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>7 \u0935\u0930\u094d\u0937 \u0915\u0940 \u0906\u092f\u0941 \u0915\u0947 \u090f\u0915 \u0930\u094b\u0917\u0940 \u092e\u0947\u0902, \u0928\u093f\u092f\u0902\u0924\u094d\u0930\u0923 \u0915\u0940 \u0924\u0941\u0932\u0928\u093e \u092e\u0947\u0902 RGX-202 \u092e\u093e\u0907\u0915\u094d\u0930\u094b\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u0940 \u0905\u092d\u093f\u0935\u094d\u092f\u0915\u094d\u0924\u093f 31.5% \u092e\u093e\u092a\u0940 \u0917\u0908\u0964<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0938\u092d\u0940 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u092e\u0947\u0902, RGX-202 \u0915\u094b \u0938\u093e\u0930\u094d\u0915\u094b\u0932\u0947\u092e\u093e \u092e\u0947\u0902 \u0909\u091a\u093f\u0924 \u0930\u0942\u092a \u0938\u0947 \u0938\u094d\u0925\u093e\u0928\u0940\u0915\u0943\u0924 \u0915\u093f\u092f\u093e \u0917\u092f\u093e, \u091c\u093f\u0938\u0938\u0947 \u092f\u0939 \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u093f\u0924 \u0939\u0941\u0906 \u0915\u093f CT-\u0921\u094b\u092e\u0947\u0928 \u0915\u0947 \u0938\u093e\u0925 \u0935\u093f\u092d\u0947\u0926\u093f\u0924 \u0938\u0902\u0930\u091a\u0928\u093e \u0909\u091a\u093f\u0924 \u0930\u0942\u092a \u0938\u0947 \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u0940 \u0915\u094b \u0932\u0915\u094d\u0937\u094d\u092f \u0915\u0930 \u0930\u0939\u0940 \u0939\u0948\u0964<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>8 \u0935\u0930\u094d\u0937 \u0938\u0947 \u0905\u0927\u093f\u0915 \u0906\u092f\u0941 \u0915\u0947 \u091a\u0932\u0928\u0947-\u092b\u093f\u0930\u0928\u0947 \u092e\u0947\u0902 \u0938\u0915\u094d\u0937\u092e \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u092e\u0947\u0902 \u0906\u0930\u091c\u0940\u090f\u0915\u094d\u0938-202 \u092e\u093e\u0907\u0915\u094d\u0930\u094b\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0905\u092d\u093f\u0935\u094d\u092f\u0915\u094d\u0924\u093f \u0915\u0947 \u092a\u0930\u093f\u0923\u093e\u092e, \u0905\u0928\u0941\u092e\u094b\u0926\u093f\u0924 \u092f\u093e \u091c\u093e\u0902\u091a\u093e\u0924\u094d\u092e\u0915 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u092e\u0947\u0902 \u092e\u093e\u0907\u0915\u094d\u0930\u094b\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u0947 \u0909\u091a\u094d\u091a\u0924\u092e \u0938\u094d\u0924\u0930 \u0939\u0948\u0902\u0964<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0924\u094d\u0935\u0930\u093f\u0924 \u0905\u0928\u0941\u092e\u094b\u0926\u0928 \u092e\u093e\u0930\u094d\u0917 \u0915\u093e \u0909\u092a\u092f\u094b\u0917 \u0915\u0930\u0924\u0947 \u0939\u0941\u090f \u092c\u093e\u092f\u094b\u0932\u0949\u091c\u093f\u0915\u094d\u0938 \u0932\u093e\u0907\u0938\u0947\u0902\u0938 \u0906\u0935\u0947\u0926\u0928 (\u092c\u0940\u090f\u0932\u090f) \u0915\u093e \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f, \u090f\u092b\u093f\u0928\u093f\u091f\u0940 \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u0915\u0947 \u0928\u093f\u0930\u094d\u0923\u093e\u092f\u0915 \u091a\u0930\u0923 \u092e\u0947\u0902 \u092a\u094d\u0930\u093e\u0925\u092e\u093f\u0915 \u0938\u092e\u093e\u092a\u0928 \u092c\u093f\u0902\u0926\u0941 \u0909\u0928 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0915\u093e \u0905\u0928\u0941\u092a\u093e\u0924 \u0939\u0948 \u091c\u093f\u0928\u0915\u0940 \u0906\u0930\u091c\u0940\u090f\u0915\u094d\u0938-202 \u092e\u093e\u0907\u0915\u094d\u0930\u094b\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0905\u092d\u093f\u0935\u094d\u092f\u0915\u094d\u0924\u093f \u0938\u092a\u094d\u0924\u093e\u0939 12 \u092e\u0947\u0902 \u226510% \u0939\u0948\u0964<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0906\u0930\u091c\u0940\u090f\u0915\u094d\u0938-202 \u0905\u0928\u0941\u092e\u094b\u0926\u093f\u0924 \u092f\u093e \u091c\u093e\u0902\u091a\u093e\u0924\u094d\u092e\u0915 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u092e\u0947\u0902 \u0915\u094d\u092f\u0942\u092a\u0940\u0938\u0940\u0906\u0930 \u0926\u094d\u0935\u093e\u0930\u093e \u092e\u093e\u092a\u0940 \u0917\u0908 \u0909\u091a\u094d\u091a\u0924\u092e \u0930\u093f\u092a\u094b\u0930\u094d\u091f \u0915\u0940 \u0917\u0908 \u0935\u0947\u0915\u094d\u091f\u0930 \u091c\u0940\u0928\u094b\u092e \u092a\u094d\u0930\u0924\u093f\u092f\u094b\u0902 (4.9-55.4) \u0915\u094b \u092d\u0940 \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u093f\u0924 \u0915\u0930\u0924\u093e \u0939\u0948\u0964<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>REGENXBIO \u0928\u0947 RGX-202 \u0915\u0947 AFFINITY DUCHENNE\u00ae \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0915\u0947 \u091a\u0930\u0923 I\/II \u092d\u093e\u0917 \u092e\u0947\u0902 \u0926\u094b \u0905\u0924\u093f\u0930\u093f\u0915\u094d\u0924 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0938\u0947 \u092a\u094d\u0930\u093e\u092a\u094d\u0924 \u0928\u090f, \u0938\u0915\u093e\u0930\u093e\u0924\u094d\u092e\u0915 \u0905\u0902\u0924\u0930\u093f\u092e \u0921\u0947\u091f\u093e \u0915\u0940 \u0930\u093f\u092a\u094b\u0930\u094d\u091f \u0915\u0940 \u0939\u0948\u0964 RGX-202, \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 (\u0921\u094d\u092f\u0942\u0936\u0947\u0928) \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u0935\u093f\u092d\u0947\u0926\u093f\u0924 \u091c\u093e\u0902\u091a\u093e\u0924\u094d\u092e\u0915 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0939\u0948\u0964 \u092a\u0930\u093f\u0923\u093e\u092e 2025 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u090f\u0938\u094b\u0938\u093f\u090f\u0936\u0928 (MDA) \u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u0914\u0930 \u0935\u0948\u091c\u094d\u091e\u093e\u0928\u093f\u0915 \u0938\u092e\u094d\u092e\u0947\u0932\u0928 \u092e\u0947\u0902 \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924 \u0915\u093f\u090f \u0917\u090f\u0964 RgX-202 \u0915\u0947 \u092a\u094d\u0930\u092e\u0941\u0916 \u0928\u093f\u0937\u094d\u0915\u0930\u094d\u0937\u094b\u0902 \u092e\u0947\u0902 \u0936\u093e\u092e\u093f\u0932 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