{"id":3230,"date":"2025-03-17T14:28:46","date_gmt":"2025-03-17T11:28:46","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=3230"},"modified":"2025-03-17T14:28:48","modified_gmt":"2025-03-17T11:28:48","slug":"avidity-biosciences-announces-positive-topline-del-zota-data-showing-consistent-statistically-significant-improvements-in-dystrophin","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/hi\/avidity-biosciences-announces-positive-topline-del-zota-data-showing-consistent-statistically-significant-improvements-in-dystrophin\/","title":{"rendered":"Avidity Biosciences \u0928\u0947 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u092e\u0947\u0902 \u0932\u0917\u093e\u0924\u093e\u0930, \u0938\u093e\u0902\u0916\u094d\u092f\u093f\u0915\u0940\u092f \u0930\u0942\u092a \u0938\u0947 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0938\u0941\u0927\u093e\u0930 \u0926\u093f\u0916\u093e\u0924\u0947 \u0939\u0941\u090f \u0938\u0915\u093e\u0930\u093e\u0924\u094d\u092e\u0915 \u091f\u0949\u092a\u0932\u093e\u0907\u0928 \u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e \u0921\u0947\u091f\u093e \u0915\u0940 \u0918\u094b\u0937\u0923\u093e \u0915\u0940"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Avidity Biosciences \u0928\u0947 \u0938\u0915\u093e\u0930\u093e\u0924\u094d\u092e\u0915 \u091f\u0949\u092a\u0932\u093e\u0907\u0928 \u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e \u0921\u0947\u091f\u093e \u0915\u0940 \u0918\u094b\u0937\u0923\u093e \u0915\u0940 \u0939\u0948, \u091c\u094b \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u0938\u0947 \u092a\u0940\u0921\u093c\u093f\u0924 \u091a\u0930\u0923 1\/2 EXPLORE44\u00ae \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u092e\u0947\u0902 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928, \u090f\u0915\u094d\u0938\u0949\u0928 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0914\u0930 \u0915\u094d\u0930\u093f\u090f\u091f\u093f\u0928 \u0915\u093e\u0907\u0928\u0947\u091c \u092e\u0947\u0902 \u0932\u0917\u093e\u0924\u093e\u0930, \u0938\u093e\u0902\u0916\u094d\u092f\u093f\u0915\u0940\u092f \u0930\u0942\u092a \u0938\u0947 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0938\u0941\u0927\u093e\u0930 \u0926\u093f\u0916\u093e \u0930\u0939\u093e \u0939\u0948, \u091c\u094b \u090f\u0915\u094d\u0938\u0949\u0928 44 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0915\u0947 \u0932\u093f\u090f \u0909\u0924\u094d\u0924\u0930\u0926\u093e\u092f\u0940 \u0939\u0948\u0902\u0964<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u092f\u0939 \u0921\u0947\u091f\u093e 16-19 \u092e\u093e\u0930\u094d\u091a, 2025 \u0915\u094b \u0921\u0932\u093e\u0938, \u091f\u0947\u0915\u094d\u0938\u093e\u0938 \u092e\u0947\u0902 \u0906\u092f\u094b\u091c\u093f\u0924 \u0939\u094b\u0928\u0947 \u0935\u093e\u0932\u0947 2025 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u090f\u0938\u094b\u0938\u093f\u090f\u0936\u0928 (\u090f\u092e\u0921\u0940\u090f) \u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u0914\u0930 \u0935\u0948\u091c\u094d\u091e\u093e\u0928\u093f\u0915 \u0938\u092e\u094d\u092e\u0947\u0932\u0928 \u092e\u0947\u0902 \u092e\u094c\u0916\u093f\u0915 \u0914\u0930 \u092a\u094b\u0938\u094d\u091f\u0930 \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924\u093f \u092e\u0947\u0902 \u0909\u091c\u093e\u0917\u0930 \u0915\u093f\u092f\u093e \u091c\u093e\u090f\u0917\u093e\u0964<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Avidity Biosciences EXPLORE44 (\u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e) \u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u092a\u0930\u0940\u0915\u094d\u0937\u0923<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">&quot;\u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e \u0928\u0947 \u0915\u0908 \u0909\u092a\u093e\u092f\u094b\u0902 \u092e\u0947\u0902 \u0909\u0932\u094d\u0932\u0947\u0916\u0928\u0940\u092f \u0938\u0941\u0927\u093e\u0930 \u0926\u093f\u0916\u093e\u090f \u0939\u0948\u0902, \u091c\u093f\u0938\u092e\u0947\u0902 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093c\u093f\u0928 \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u092e\u0947\u0902 \u092a\u0930\u094d\u092f\u093e\u092a\u094d\u0924 \u0935\u0943\u0926\u094d\u0927\u093f \u0914\u0930 \u0938\u093f\u0930\u094d\u092b\u093c \u0924\u0940\u0928 \u0916\u0941\u0930\u093e\u0915 \u0915\u0947 \u092c\u093e\u0926 \u0938\u0940\u0930\u092e \u0915\u094d\u0930\u093f\u090f\u091f\u093f\u0928 \u0915\u093e\u0907\u0928\u0947\u091c \u0915\u0947 \u0938\u094d\u0924\u0930 \u092e\u0947\u0902 \u0909\u0932\u094d\u0932\u0947\u0916\u0928\u0940\u092f \u0915\u092e\u0940 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948 \u091c\u094b \u0932\u0917\u092d\u0917 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0939\u094b \u0917\u092f\u093e \u0939\u0948\u0964 \u0907\u0924\u0928\u0947 \u0915\u092e \u0938\u092e\u092f \u092e\u0947\u0902 \u0907\u0928 \u092a\u0930\u093f\u0923\u093e\u092e\u094b\u0902 \u0915\u0940 \u0938\u094d\u0925\u093f\u0930\u0924\u093e, \u0905\u0928\u0941\u0915\u0942\u0932 \u0938\u0941\u0930\u0915\u094d\u0937\u093e \u0914\u0930 \u0938\u0939\u0928\u0936\u0940\u0932\u0924\u093e \u0915\u0947 \u0938\u093e\u0925 \u092e\u093f\u0932\u0915\u0930, del-zota \u0915\u0940 \u0915\u094d\u0937\u092e\u0924\u093e \u0915\u094b \u0930\u0947\u0916\u093e\u0902\u0915\u093f\u0924 \u0915\u0930\u0924\u093e \u0939\u0948 \u091c\u094b \u090f\u0915\u094d\u0938\u0949\u0928 44 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0915\u0947 \u0932\u093f\u090f \u0909\u0924\u094d\u0924\u0930\u0926\u093e\u092f\u0940 \u0906\u0928\u0941\u0935\u0902\u0936\u093f\u0915 \u0935\u0947\u0930\u093f\u090f\u0902\u091f \u0935\u093e\u0932\u0947 DMD \u0938\u0947 \u092a\u0940\u0921\u093c\u093f\u0924 \u0935\u094d\u092f\u0915\u094d\u0924\u093f\u092f\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u0905\u092d\u0942\u0924\u092a\u0942\u0930\u094d\u0935 \u0909\u092a\u091a\u093e\u0930 \u092c\u0928 \u0938\u0915\u0924\u093e \u0939\u0948,&quot; \u0905\u0930\u0935\u093f\u0928\u094d\u0926\u0928 \u0935\u0940\u0930\u092a\u093e\u0902\u0921\u093f\u092f\u0928, \u090f\u092e\u0921\u0940, \u092c\u093e\u0932 \u0930\u094b\u0917 \u0915\u0947 \u090f\u0938\u094b\u0938\u093f\u090f\u091f \u092a\u094d\u0930\u094b\u092b\u0947\u0938\u0930, \u0905\u0930\u0915\u0902\u0938\u093e\u0938 \u092e\u0947\u0921\u093f\u0915\u0932 \u0938\u093e\u0907\u0902\u0938\u0947\u091c \u0914\u0930 \u0905\u0930\u0915\u0902\u0938\u093e\u0938 \u091a\u093f\u0932\u094d\u0921\u094d\u0930\u0928\u094d\u0938 \u0939\u0949\u0938\u094d\u092a\u093f\u091f\u0932 \u0935\u093f\u0936\u094d\u0935\u0935\u093f\u0926\u094d\u092f\u093e\u0932\u092f \u0928\u0947 \u0915\u0939\u093e\u0964<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&quot;\u092f\u0947 \u092a\u0930\u093f\u0923\u093e\u092e \u0921\u0940\u090f\u092e\u0921\u0940 \u0938\u0947 \u092a\u094d\u0930\u092d\u093e\u0935\u093f\u0924 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0914\u0930 \u092a\u0930\u093f\u0935\u093e\u0930\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0928\u0908 \u0909\u092e\u094d\u092e\u0940\u0926 \u0932\u0947\u0915\u0930 \u0906\u090f \u0939\u0948\u0902, \u091c\u093f\u0928\u094d\u0939\u0947\u0902 \u0932\u0915\u094d\u0937\u093f\u0924 \u0909\u092a\u091a\u093e\u0930\u094b\u0902 \u0915\u0940 \u0924\u0924\u094d\u0915\u093e\u0932 \u0906\u0935\u0936\u094d\u092f\u0915\u0924\u093e \u0939\u0948, \u091c\u094b \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u0940 \u0905\u0916\u0902\u0921\u0924\u093e \u0915\u094b \u092c\u0928\u093e\u090f \u0930\u0916 \u0938\u0915\u0924\u0947 \u0939\u0948\u0902 \u0914\u0930 \u0938\u0902\u092d\u0935\u0924\u0903 \u0907\u0938 \u0930\u094b\u0917 \u0938\u0947 \u091c\u0941\u0921\u093c\u0940 \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u0940 \u0915\u092e\u091c\u094b\u0930\u0940 \u0914\u0930 \u0915\u093e\u0930\u094d\u092f\u0915\u094d\u0937\u092e\u0924\u093e \u0915\u0940 \u0939\u093e\u0928\u093f \u0915\u0940 \u092a\u094d\u0930\u0917\u0924\u093f \u0915\u094b \u0930\u094b\u0915 \u0938\u0915\u0924\u0947 \u0939\u0948\u0902 \u092f\u093e \u0926\u0947\u0930\u0940 \u0915\u0930 \u0938\u0915\u0924\u0947 \u0939\u0948\u0902\u0964&quot;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e \u0915\u094d\u092f\u093e \u0939\u0948?<\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-1024x576.jpg\" alt=\"Avidity Biosciences \u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e EXPLORE44 \u090f\u0915\u094d\u0938\u0949\u0928 44 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917\" class=\"wp-image-3234\" title=\"\" srcset=\"https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-1024x576.jpg 1024w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-300x169.jpg 300w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-768x432.jpg 768w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-1536x864.jpg 1536w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-18x10.jpg 18w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-747x420.jpg 747w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-150x84.jpg 150w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-696x392.jpg 696w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota-1068x601.jpg 1068w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/03\/Avidity-Biosciences-Del-Zota.jpg 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e \u0915\u094b \u092b\u0949\u0938\u094d\u092b\u094b\u0930\u094b\u0921\u093e\u092f\u092e\u093f\u0921\u0947\u091f \u092e\u0949\u0930\u094d\u092b\u094b\u0932\u093f\u0928\u094b \u0911\u0932\u093f\u0917\u094b\u092e\u0930\u094d\u0938 (PMOs) \u0915\u094b \u0915\u0902\u0915\u093e\u0932 \u0914\u0930 \u0939\u0943\u0926\u092f \u0915\u0940 \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u0947 \u090a\u0924\u0915\u094b\u0902 \u0924\u0915 \u092a\u0939\u0941\u0901\u091a\u093e\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0921\u093f\u091c\u093c\u093e\u0907\u0928 \u0915\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948 \u0924\u093e\u0915\u093f \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093c\u093f\u0928 \u091c\u0940\u0928 \u0915\u0947 \u090f\u0915\u094d\u0938\u0949\u0928 44 \u0915\u094b \u0935\u093f\u0936\u0947\u0937 \u0930\u0942\u092a \u0938\u0947 \u091b\u094b\u0921\u093c \u0926\u093f\u092f\u093e \u091c\u093e \u0938\u0915\u0947 \u0914\u0930 \u0932\u0917\u092d\u0917 \u092a\u0942\u0930\u0940 \u0932\u0902\u092c\u093e\u0908 \u0915\u0947 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093c\u093f\u0928 \u0915\u093e \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u0938\u0915\u094d\u0937\u092e \u0915\u093f\u092f\u093e \u091c\u093e \u0938\u0915\u0947\u0964 \u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e \u0915\u094b \u092f\u0942\u090f\u0938 \u092b\u093c\u0942\u0921 \u090f\u0902\u0921 \u0921\u094d\u0930\u0917 \u090f\u0921\u092e\u093f\u0928\u093f\u0938\u094d\u091f\u094d\u0930\u0947\u0936\u0928 (FDA) \u0914\u0930 \u092f\u0942\u0930\u094b\u092a\u093f\u092f\u0928 \u092e\u0947\u0921\u093f\u0938\u093f\u0928 \u090f\u091c\u0947\u0902\u0938\u0940 (EMA) \u0926\u094d\u0935\u093e\u0930\u093e \u0905\u0928\u093e\u0925 \u092a\u0926\u0928\u093e\u092e \u0926\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948\u0964 FDA \u0915\u094b del-zota \u0926\u0941\u0930\u094d\u0932\u092d \u092c\u093e\u0932 \u0930\u094b\u0917 \u0914\u0930 \u092b\u093c\u093e\u0938\u094d\u091f \u091f\u094d\u0930\u0948\u0915 \u092a\u0926\u0928\u093e\u092e \u092d\u0940 \u0926\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948\u0964 \u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e DMD \u0915\u0947 \u0909\u092a\u091a\u093e\u0930 \u0915\u0947 \u0932\u093f\u090f \u090f\u0935\u093f\u0921\u093f\u091f\u0940 \u092e\u0947\u0902 \u0935\u0930\u094d\u0924\u092e\u093e\u0928 \u092e\u0947\u0902 \u0935\u093f\u0915\u0938\u093f\u0924 \u0915\u093f\u090f \u091c\u093e \u0930\u0939\u0947 \u0915\u0908 AOC \u092e\u0947\u0902 \u0938\u0947 \u092a\u0939\u0932\u093e \u0939\u0948\u0964<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u090f\u092e\u0921\u0940\u090f \u092e\u0947\u0902 \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924 \u0906\u0902\u0915\u0921\u093c\u0947 1\u091f\u0940\u092a\u094037\u091f\u0940 \u0915\u0947 5 \u092e\u093f\u0932\u0940\u0917\u094d\u0930\u093e\u092e\/\u0915\u093f\u0917\u094d\u0930\u093e \u0914\u0930 10 \u092e\u093f\u0932\u0940\u0917\u094d\u0930\u093e\u092e\/\u0915\u093f\u0917\u094d\u0930\u093e \u0926\u094b\u0928\u094b\u0902 \u0938\u092e\u0942\u0939\u094b\u0902 \u092e\u0947\u0902 \u0938\u092d\u0940 \u092e\u093e\u092a\u0926\u0902\u0921\u094b\u0902 \u092a\u0930 \u0938\u0941\u0938\u0902\u0917\u0924 \u0921\u0947\u091f\u093e \u0915\u094b \u0909\u091c\u093e\u0917\u0930 \u0915\u0930\u0924\u0947 \u0939\u0948\u0902, \u091c\u093f\u0928\u092e\u0947\u0902 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u092a\u0940\u090f\u092e\u0913 \u0915\u093e \u0932\u0915\u094d\u0937\u093f\u0924 \u0935\u093f\u0924\u0930\u0923 \u091c\u093f\u0938\u0915\u0947 \u092a\u0930\u093f\u0923\u093e\u092e\u0938\u094d\u0935\u0930\u0942\u092a \u0915\u0902\u0915\u093e\u0932 \u0915\u0940 \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u092e\u0947\u0902 \u0932\u0917\u092d\u0917 200 \u090f\u0928\u090f\u092e \u0915\u0940 \u090a\u0924\u0915 \u0938\u093e\u0902\u0926\u094d\u0930\u0924\u093e \u0939\u094b\u0924\u0940 \u0939\u0948;<\/li>\n\n\n\n<li>\u090f\u0915\u094d\u0938\u0949\u0928 44 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u092e\u0947\u0902 \u0932\u0917\u092d\u0917 40% \u0915\u0940 \u0938\u093e\u0902\u0916\u094d\u092f\u093f\u0915\u0940\u092f \u0930\u0942\u092a \u0938\u0947 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0935\u0943\u0926\u094d\u0927\u093f;<\/li>\n\n\n\n<li>\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u092e\u0947\u0902 \u0932\u0917\u092d\u0917 25% \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0915\u0940 \u0938\u093e\u0902\u0916\u094d\u092f\u093f\u0915\u0940\u092f \u0930\u0942\u092a \u0938\u0947 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0935\u0943\u0926\u094d\u0927\u093f \u0939\u0941\u0908 \u0914\u0930 \u0915\u0941\u0932 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0915\u094b 58% \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0924\u0915 \u092c\u0939\u093e\u0932 \u0915\u093f\u092f\u093e \u0917\u092f\u093e;<\/li>\n\n\n\n<li>\u0906\u0927\u093e\u0930 \u0930\u0947\u0916\u093e \u0915\u0940 \u0924\u0941\u0932\u0928\u093e \u092e\u0947\u0902 80% \u0938\u0947 \u0905\u0927\u093f\u0915 \u0915\u0940 \u0915\u092e\u0940 \u0915\u0947 \u0938\u093e\u0925 \u0915\u094d\u0930\u093f\u090f\u091f\u093f\u0928 \u0915\u093e\u0907\u0928\u0947\u091c \u0915\u0947 \u0938\u094d\u0924\u0930 \u092e\u0947\u0902 \u0932\u0917\u092d\u0917 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0938\u094d\u0924\u0930 \u0924\u0915 \u0915\u092e\u0940:\n<ul class=\"wp-block-list\">\n<li>\u0907\u0938\u0940 \u0924\u0930\u0939, \u092a\u094d\u0932\u0947\u0938\u092c\u094b \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0928\u0947 del-zota \u0915\u0947 \u0938\u093e\u0925 \u0909\u092a\u091a\u093e\u0930 \u0915\u0947 \u092c\u093e\u0926 \u0915\u094d\u0930\u093f\u090f\u091f\u093f\u0928 \u0915\u093e\u0907\u0928\u0947\u091c \u0915\u0947 \u0938\u094d\u0924\u0930 \u092e\u0947\u0902 \u0932\u0917\u092d\u0917 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0938\u094d\u0924\u0930 \u0924\u0915 \u0915\u092e\u0940 \u0915\u093e \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u0928 \u0915\u093f\u092f\u093e;<\/li>\n\n\n\n<li>EXPLORE44-OLE \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u092e\u0947\u0902 \u090f\u0915 \u0935\u0930\u094d\u0937 \u0924\u0915 \u0928\u093f\u0930\u0902\u0924\u0930 \u0909\u092a\u091a\u093e\u0930 \u0915\u0947 \u0938\u093e\u0925 \u0915\u094d\u0930\u093f\u090f\u091f\u093f\u0928 \u0915\u093e\u0907\u0928\u0947\u091c \u0915\u0947 \u0938\u094d\u0924\u0930 \u092e\u0947\u0902 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0915\u092e\u0940 \u0926\u0947\u0916\u0940 \u0917\u0908; \u0924\u0925\u093e,<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>\u0921\u0947\u0932-\u091c\u093c\u094b\u091f\u093e \u0928\u0947 \u0926\u094b\u0928\u094b\u0902 \u0916\u0941\u0930\u093e\u0915\u094b\u0902 \u092a\u0930 \u0905\u0928\u0941\u0915\u0942\u0932 \u0938\u0941\u0930\u0915\u094d\u0937\u093e \u0914\u0930 \u0938\u0939\u0928\u0936\u0940\u0932\u0924\u093e \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u093f\u0924 \u0915\u0940, \u091c\u093f\u0938\u092e\u0947\u0902 \u0905\u0927\u093f\u0915\u093e\u0902\u0936 \u0909\u092a\u091a\u093e\u0930 \u0906\u0915\u0938\u094d\u092e\u093f\u0915 \u092a\u094d\u0930\u0924\u093f\u0915\u0942\u0932 \u0918\u091f\u0928\u093e\u090f\u0902 (\u091f\u0940\u0908\u090f\u0908) \u0939\u0932\u094d\u0915\u0940 \u092f\u093e \u092e\u0927\u094d\u092f\u092e \u0925\u0940\u0902\u0964<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0914\u0930 \u0905\u0927\u093f\u0915 \u091c\u093e\u0928\u0947\u0902:<\/strong> <a href=\"https:\/\/dmdwarrior.com\/hi\/next-generation-exon-skipping-therapies-for-duchenne-muscular-dystrophy\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u0915\u0947 \u0909\u092a\u091a\u093e\u0930 \u0915\u0947 \u0932\u093f\u090f \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0940 \u090f\u0915\u094d\u0938\u0949\u0928 \u0938\u094d\u0915\u093f\u092a\u093f\u0902\u0917 \u0925\u0947\u0930\u0947\u092a\u0940 \u0935\u093f\u0915\u0938\u093f\u0924 \u0915\u0940 \u0917\u0908<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Avidity Biosciences Announces Positive Topline Del-zota Data Showing Consistent, Statistically Significant Improvements in Dystrophin, Exon Skipping, and Creatine Kinase in Phase 1\/2 EXPLORE44\u00ae Trial Participants with Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping. The data will be highlighted in an oral and poster presentation at the 2025 Muscular Dystrophy Association (MDA) Clinical &amp; Scientific [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3232,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[126,298,141,127,246,299],"class_list":["post-3230","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-avidity-biosciences","tag-del-zota","tag-exon-44","tag-exon-44-skipping","tag-exon-44-skipping-therapies","tag-explore44"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/3230","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/comments?post=3230"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/3230\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media\/3232"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media?parent=3230"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/categories?post=3230"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/tags?post=3230"}],"curies":[{"name":"\u0921\u092c\u094d\u0932\u094d\u092f\u0942\u092a\u0940","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}