{"id":2961,"date":"2025-02-18T15:46:12","date_gmt":"2025-02-18T12:46:12","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2961"},"modified":"2025-03-07T12:57:05","modified_gmt":"2025-03-07T09:57:05","slug":"solid-biosciences-reports-positive-initial-clinical-data-from-next-generation-duchenne-gene-therapy-candidate-sgt-003","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/hi\/solid-biosciences-reports-positive-initial-clinical-data-from-next-generation-duchenne-gene-therapy-candidate-sgt-003\/","title":{"rendered":"Solid Biosciences \u0928\u0947 \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0909\u092e\u094d\u092e\u0940\u0926\u0935\u093e\u0930 SGT-003 \u0938\u0947 \u0938\u0915\u093e\u0930\u093e\u0924\u094d\u092e\u0915 \u092a\u094d\u0930\u093e\u0930\u0902\u092d\u093f\u0915 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u0921\u0947\u091f\u093e \u0915\u0940 \u0930\u093f\u092a\u094b\u0930\u094d\u091f \u0926\u0940"},"content":{"rendered":"

\u0928\u094d\u092f\u0942\u0930\u094b\u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0914\u0930 \u0939\u0943\u0926\u092f \u0938\u0902\u092c\u0902\u0927\u0940 \u092c\u0940\u092e\u093e\u0930\u093f\u092f\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0938\u091f\u0940\u0915 \u0906\u0928\u0941\u0935\u0902\u0936\u093f\u0915 \u0926\u0935\u093e\u0907\u092f\u093e\u0902 \u0935\u093f\u0915\u0938\u093f\u0924 \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u0940 \u0932\u093e\u0907\u092b \u0938\u093e\u0907\u0902\u0938\u0947\u091c \u0915\u0902\u092a\u0928\u0940 Solid Biosciences \u0928\u0947 \u0906\u091c SGT-003 \u0915\u093e \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u0947 \u091a\u0930\u0923 1\/2 INSPIRE DUCHENNE \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0938\u0947 \u0938\u0915\u093e\u0930\u093e\u0924\u094d\u092e\u0915 \u092a\u094d\u0930\u093e\u0930\u0902\u092d\u093f\u0915 \u0921\u0947\u091f\u093e \u0915\u0940 \u0918\u094b\u0937\u0923\u093e \u0915\u0940, \u091c\u094b \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 (\u0921\u094d\u092f\u0942\u091a\u0947\u0928) \u0915\u0947 \u0909\u092a\u091a\u093e\u0930 \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u093e \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0909\u0924\u094d\u092a\u093e\u0926 \u0909\u092e\u094d\u092e\u0940\u0926\u0935\u093e\u0930 \u0939\u0948\u0964 \u092a\u0939\u0932\u0947 \u0924\u0940\u0928 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u092e\u0947\u0902 \u0930\u093f\u092a\u094b\u0930\u094d\u091f \u0915\u093f\u090f \u0917\u090f \u0905\u0902\u0924\u0930\u093f\u092e 90-\u0926\u093f\u0935\u0938\u0940\u092f \u092c\u093e\u092f\u094b\u092a\u094d\u0938\u0940 \u0921\u0947\u091f\u093e \u0928\u0947 \u0935\u0947\u0938\u094d\u091f\u0930\u094d\u0928 \u092c\u094d\u0932\u0949\u091f \u0926\u094d\u0935\u093e\u0930\u093e \u092e\u093e\u092a\u0940 \u0917\u0908 110% \u0915\u0940 \u0914\u0938\u0924 \u092e\u093e\u0907\u0915\u094d\u0930\u094b\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0905\u092d\u093f\u0935\u094d\u092f\u0915\u094d\u0924\u093f \u0914\u0930 \u0915\u0908 \u092c\u093e\u092f\u094b\u092e\u093e\u0930\u094d\u0915\u0930 \u092e\u0947\u0902 \u0938\u0941\u0927\u093e\u0930 \u0926\u093f\u0916\u093e\u092f\u093e, \u091c\u094b \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u093f\u092f\u094b\u0902 \u0915\u0947 \u0938\u094d\u0935\u093e\u0938\u094d\u0925\u094d\u092f \u0914\u0930 \u0932\u091a\u0940\u0932\u0947\u092a\u0928 \u0915\u0947 \u0938\u0902\u0915\u0947\u0924\u0915 \u0939\u0948\u0902\u0964<\/p>\n\n\n\n

\u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0909\u092e\u094d\u092e\u0940\u0926\u0935\u093e\u0930 SGT-003 \u0915\u093e \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u0921\u0947\u091f\u093e<\/h2>\n\n\n\n
    \n
  1. 110% (N=3) \u0915\u0940 \u0914\u0938\u0924 \u092e\u093e\u0907\u0915\u094d\u0930\u094b\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0905\u092d\u093f\u0935\u094d\u092f\u0915\u094d\u0924\u093f \u0914\u0930 \u0915\u0908 \u0905\u0924\u093f\u0930\u093f\u0915\u094d\u0924 \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u0940 \u0938\u094d\u0935\u093e\u0938\u094d\u0925\u094d\u092f \u092c\u093e\u092f\u094b\u092e\u093e\u0930\u094d\u0915\u0930\u094b\u0902 \u092e\u0947\u0902 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0938\u0941\u0927\u093e\u0930, \u0905\u0917\u0932\u0940 \u092a\u0940\u0922\u093c\u0940 \u0915\u0947 \u0938\u0930\u094d\u0935\u0936\u094d\u0930\u0947\u0937\u094d\u0920 \u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0909\u092e\u094d\u092e\u0940\u0926\u0935\u093e\u0930 \u0915\u0947 \u0930\u0942\u092a \u092e\u0947\u0902 SGT-003 \u0915\u0940 \u0915\u094d\u0937\u092e\u0924\u093e \u0915\u093e \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0924\u0947 \u0939\u0948\u0902\u0964<\/li>\n\n\n\n
  2. \u0938\u0902\u092d\u093e\u0935\u093f\u0924 \u0939\u0943\u0926\u092f \u0938\u0902\u092c\u0902\u0927\u0940 \u0932\u093e\u092d \u0915\u0947 \u0909\u0924\u094d\u0938\u093e\u0939\u091c\u0928\u0915 \u092a\u094d\u0930\u093e\u0930\u0902\u092d\u093f\u0915 \u0938\u0902\u0915\u0947\u0924 \u0926\u0947\u0916\u0947 \u0917\u090f\u0964<\/li>\n\n\n\n
  3. 11 \u092b\u0930\u0935\u0930\u0940, 2025 \u0924\u0915 \u0916\u0941\u0930\u093e\u0915 \u0926\u093f\u090f \u0917\u090f 6 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u092e\u0947\u0902 SGT-003 \u0915\u094b \u0905\u091a\u094d\u091b\u0940 \u0924\u0930\u0939 \u0938\u0947 \u0938\u0939\u0928 \u0915\u093f\u092f\u093e \u0917\u092f\u093e, \u0924\u0925\u093e \u0915\u094b\u0908 \u0917\u0902\u092d\u0940\u0930 \u092a\u094d\u0930\u0924\u093f\u0915\u0942\u0932 \u0918\u091f\u0928\u093e \u0928\u0939\u0940\u0902 \u0926\u0947\u0916\u0940 \u0917\u0908\u0964<\/li>\n\n\n\n
  4. \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0915\u093e \u0928\u093e\u092e\u093e\u0902\u0915\u0928 \u091c\u093e\u0930\u0940 \u0939\u0948, 17 \u092b\u0930\u0935\u0930\u0940 2025 \u0915\u094b 7\u0935\u0947\u0902 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u0940 \u0915\u094b \u0916\u0941\u0930\u093e\u0915 \u0926\u0940 \u091c\u093e\u090f\u0917\u0940; \u0915\u0902\u092a\u0928\u0940 \u0915\u094b \u0909\u092e\u094d\u092e\u0940\u0926 \u0939\u0948 \u0915\u093f 2025 \u0915\u0940 \u091a\u094c\u0925\u0940 \u0924\u093f\u092e\u093e\u0939\u0940 \u0924\u0915 \u0932\u0917\u092d\u0917 20 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u0915\u094b \u0916\u0941\u0930\u093e\u0915 \u0926\u0940 \u091c\u093e\u090f\u0917\u0940\u0964<\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"

    Solid Biosciences, a life sciences company developing precision genetic medicines for neuromuscular and cardiac diseases, today announced positive initial data from the Phase 1\/2 INSPIRE DUCHENNE trial evaluating SGT-003, a next-generation gene therapy product candidate intended for the treatment of Duchenne muscular dystrophy (Duchenne). Interim 90-day biopsy data reported in the first three participants showed […]<\/p>\n","protected":false},"author":1,"featured_media":2963,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[137,110,170,109],"class_list":["post-2961","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-clinical-trial","tag-sgt-003","tag-sgt-003-gene-therapy","tag-solid-biosciences"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/2961","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/comments?post=2961"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/2961\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media\/2963"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media?parent=2961"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/categories?post=2961"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/tags?post=2961"}],"curies":[{"name":"\u0921\u092c\u094d\u0932\u094d\u092f\u0942\u092a\u0940","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}