{"id":2190,"date":"2025-01-02T01:50:35","date_gmt":"2025-01-01T22:50:35","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2190"},"modified":"2025-01-02T02:00:28","modified_gmt":"2025-01-01T23:00:28","slug":"is-duchenne-gene-therapy-a-suitable-treatment-despite-its-immunogenic-class-effect","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/hi\/is-duchenne-gene-therapy-a-suitable-treatment-despite-its-immunogenic-class-effect\/","title":{"rendered":"\u0915\u094d\u092f\u093e \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0905\u092a\u0928\u0947 \u092a\u094d\u0930\u0924\u093f\u0930\u0915\u094d\u0937\u093e\u091c\u0928\u094d\u092f \u0935\u0930\u094d\u0917 \u092a\u094d\u0930\u092d\u093e\u0935 \u0915\u0947 \u092c\u093e\u0935\u091c\u0942\u0926 \u090f\u0915 \u0909\u092a\u092f\u0941\u0915\u094d\u0924 \u0909\u092a\u091a\u093e\u0930 \u0939\u0948?"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u0915\u093e\u0930\u094d\u0921\u093f\u092f\u094b\u092e\u093e\u092f\u094b\u092a\u0948\u0925\u0940 \u092f\u093e \u0936\u094d\u0935\u0938\u0928 \u091c\u091f\u093f\u0932\u0924\u093e\u0913\u0902 \u0915\u0947 \u092a\u0930\u093f\u0923\u093e\u092e\u0938\u094d\u0935\u0930\u0942\u092a \u092a\u094d\u0930\u0917\u0924\u093f\u0936\u0940\u0932 \u092e\u093e\u0902\u0938\u092a\u0947\u0936\u0940 \u0915\u092e\u091c\u093c\u094b\u0930\u0940 \u0914\u0930 \u0905\u0902\u0924\u0924\u0903 \u092e\u0943\u0924\u094d\u092f\u0941 \u0926\u0930 \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 (\u0921\u0940\u090f\u092e\u0921\u0940) \u0915\u0940 \u092a\u0939\u091a\u093e\u0928 \u0939\u0948, \u091c\u094b \u090f\u0915 \u0917\u0902\u092d\u0940\u0930 \u090f\u0915\u094d\u0938-\u0932\u093f\u0902\u0915\u094d\u0921 \u0935\u093f\u0915\u093e\u0930 \u0939\u0948\u0964 \u0935\u0930\u094d\u0924\u092e\u093e\u0928 \u092e\u0947\u0902, \u0921\u0940\u090f\u092e\u0921\u0940 \u0915\u0947 \u0932\u093f\u090f \u0915\u094b\u0908 \u0907\u0932\u093e\u091c \u0928\u0939\u0940\u0902 \u0939\u0948, \u0914\u0930 \u092e\u093e\u0928\u0915 \u0909\u092a\u091a\u093e\u0930\u094b\u0902 \u0915\u093e \u092a\u094d\u0930\u093e\u0925\u092e\u093f\u0915 \u0927\u094d\u092f\u093e\u0928 \u0932\u0915\u094d\u0937\u0923 \u092a\u094d\u0930\u092c\u0902\u0927\u0928 \u092a\u0930 \u0939\u0948\u0964 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0907\u092e\u094d\u092f\u0942\u0928\u094b\u0938\u092a\u094d\u0930\u0947\u0938\u093f\u0935 \u0909\u092a\u093e\u092f\u094b\u0902 \u0914\u0930 \u0905\u0928\u0941\u0915\u0942\u0932\u093f\u0924 \u0935\u0947\u0915\u094d\u091f\u0930 \u0921\u093f\u091c\u093c\u093e\u0907\u0928\u094b\u0902 \u0915\u094b \u0928\u093f\u092f\u094b\u091c\u093f\u0924 \u0915\u0930\u0915\u0947 \u0930\u094b\u0917 \u0915\u0947 \u0906\u0928\u0941\u0935\u0902\u0936\u093f\u0915 \u0915\u093e\u0930\u0923 \u0915\u094b \u0905\u0927\u093f\u0915 \u092a\u094d\u0930\u092d\u093e\u0935\u0940 \u0922\u0902\u0917 \u0938\u0947 \u0938\u0902\u092c\u094b\u0927\u093f\u0924 \u0915\u0930 \u0938\u0915\u0924\u0940 \u0939\u0948\u0964<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0921\u094d\u092f\u0942\u0936\u0947\u0928 \u092e\u0938\u094d\u0915\u0941\u0932\u0930 \u0921\u093f\u0938\u094d\u091f\u094d\u0930\u0949\u092b\u0940 (\u0921\u0940\u090f\u092e\u0921\u0940) \u0930\u094b\u0917 \u092e\u0947\u0902 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0909\u092a\u091a\u093e\u0930 \u0915\u0947 \u0915\u094d\u092f\u093e \u092a\u094d\u0930\u092d\u093e\u0935 \u0939\u0948\u0902, \u0915\u094d\u092f\u093e \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0915\u093e\u092e \u0915\u0930\u0924\u0940 \u0939\u0948? \u092f\u0939\u093e\u0901 \u090f\u0915 \u0935\u094d\u092f\u093e\u092a\u0915 \u0935\u093f\u0936\u094d\u0932\u0947\u0937\u0923 \u0926\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948\u0964<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.tandfonline.com\/eprint\/BFZQKYN3YY3AHAVX9S27\/full?target=10.1080\/14740338.2024.2447072\" target=\"_blank\" rel=\"noreferrer noopener\">\u0914\u0930 \u092a\u0922\u093c\u0947\u0902<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/x.com\/ToshifumiYokota\" target=\"_blank\" rel=\"noreferrer noopener\">\u092a\u094d\u0930\u094b. \u0924\u094b\u0936\u0940 \u092f\u094b\u0915\u094b\u0924\u093e \u0915\u093e \u0905\u0928\u0941\u0938\u0930\u0923 \u0915\u0930\u0947\u0902<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Progressive muscle weakness and eventual mortality as a result of cardiomyopathy or respiratory complications are the hallmarks of Duchenne muscular dystrophy (DMD), a severe X-linked disorder. At present, there is no cure for DMD, and the primary focus of standard treatments is on symptom management. Gene therapies can more effectively address the genetic cause of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2192,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[66,33,72,61],"class_list":["post-2190","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-duchenne-muscular-dystrophy","tag-elevidys","tag-gene-editing","tag-gene-therapy"],"subtitle":"\u092f\u0939 \u0932\u0947\u0916 \u0905\u0917\u0938\u094d\u0924 2024 \u0924\u0915 \u0915\u0940 \u0935\u0930\u094d\u0924\u092e\u093e\u0928 \u091c\u0940\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0915\u0940 \u091c\u093e\u0902\u091a \u0915\u0930\u0947\u0917\u093e, \u091c\u093f\u0938\u092e\u0947\u0902 \u092e\u093e\u0907\u0915\u094d\u0930\u094b-\u0921\u093f\u0938\u094d\u091f\u094d\u0930\u094b\u092b\u093f\u0928 \u0921\u094d\u092f\u0942\u091a\u0947\u0928 \u0925\u0947\u0930\u0947\u092a\u0940 \u0914\u0930 \u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932\u091f\u094d\u0930\u093e\u092f\u0932\u094d\u0938.gov \u092a\u0930 \u0909\u092a\u0932\u092c\u094d\u0927 CRISPR-Cas9 \u0925\u0947\u0930\u0947\u092a\u0940 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902\u0964","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/2190","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/comments?post=2190"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/posts\/2190\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media\/2192"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/media?parent=2190"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/categories?post=2190"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/hi\/wp-json\/wp\/v2\/tags?post=2190"}],"curies":[{"name":"\u0921\u092c\u094d\u0932\u094d\u092f\u0942\u092a\u0940","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}