{"id":2159,"date":"2024-12-30T16:44:16","date_gmt":"2024-12-30T13:44:16","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2159"},"modified":"2024-12-30T16:46:51","modified_gmt":"2024-12-30T13:46:51","slug":"zebrafish-modeling-shows-promise-in-duchenne-dmd-research","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/es\/zebrafish-modeling-shows-promise-in-duchenne-dmd-research\/","title":{"rendered":"El modelado del pez cebra muestra resultados prometedores en la investigaci\u00f3n de la enfermedad de Duchenne (DMD)"},"content":{"rendered":"<p class=\"wp-block-paragraph\">El pez cebra (Danio rerio) se ha convertido en un valioso organismo modelo para investigar el desarrollo musculoesquel\u00e9tico y la fisiopatolog\u00eda de las enfermedades asociadas. Los genes clave y los procesos biol\u00f3gicos del pez cebra son muy similares a los de los seres humanos, y su r\u00e1pido desarrollo y la transparencia de sus embriones hacen que el pez cebra sea ideal para los estudios in vivo de la formaci\u00f3n de los huesos y los m\u00fasculos, as\u00ed como de los mecanismos moleculares que subyacen a los trastornos musculoesquel\u00e9ticos.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">La investigaci\u00f3n se centra en la utilidad del pez cebra para modelar diversos trastornos musculoesquel\u00e9ticos, con especial \u00e9nfasis en enfermedades \u00f3seas como la osteoporosis y la osteog\u00e9nesis imperfecta, y trastornos musculares como la distrofia muscular de Duchenne.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.mdpi.com\/2073-4409\/14\/1\/28\" target=\"_blank\" rel=\"noreferrer noopener\">Leer m\u00e1s<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Zebrafish (Danio rerio) has emerged as a valuable model organism for investigating musculoskeletal development and the pathophysiology of associated diseases. Key genes and biological processes in zebrafish are very similar to those in humans, and the rapid development and transparent embryos make zebrafish ideal for in vivo studies of bone and muscle formation as well [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2160,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[70,72,71],"class_list":["post-2159","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-crispr-cas9","tag-gene-editing","tag-zebrafish"],"subtitle":"Los peces cebra ofrecen una oportunidad \u00fanica para modelar la distrofia muscular de Duchenne debido a su maleabilidad gen\u00e9tica y su capacidad para realizar estudios de mutag\u00e9nesis a gran escala y edici\u00f3n gen\u00e9tica CRISPR-Cas9.","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/posts\/2159","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/comments?post=2159"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/posts\/2159\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/media\/2160"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/media?parent=2159"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/categories?post=2159"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/es\/wp-json\/wp\/v2\/tags?post=2159"}],"curies":[{"name":"gracias","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}