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What does Surrogate Endpoint mean in Duchenne (DMD)?

Surrogate Endpoint is a Duchenne (DMD) laboratory term, explained for patients, families, and caregivers.

Category: Biomarkers and Laboratory Measurements

Surrogate Endpoint

A measurement used in place of a direct clinical outcome because it is expected to predict a meaningful benefit. In DMD, dystrophin measurements may be considered in this context, but an increase in a surrogate marker does not automatically establish improved mobility, quality of life, or survival.

Updated November 3, 2026

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