{"id":2438,"date":"2025-01-15T12:28:10","date_gmt":"2025-01-15T09:28:10","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2438"},"modified":"2025-01-15T12:28:12","modified_gmt":"2025-01-15T09:28:12","slug":"the-fda-designates-ips-hearts-givi-mpc-stem-cell-therapy-for-becker-muscular-dystrophy-an-orphan-drug","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/de\/the-fda-designates-ips-hearts-givi-mpc-stem-cell-therapy-for-becker-muscular-dystrophy-an-orphan-drug\/","title":{"rendered":"Mit der Zulassungsnummer FDA wird die GIVI-MPC-Stammzelltherapie von IPS HEART f\u00fcr Becker-Muskeldystrophie zum Orphan Drug erkl\u00e4rt"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Dem Wirkstoff FDA wurde von IPS HEART der Status eines Orphan-Drug-Pr\u00e4parats (ODD) f\u00fcr GIVI-MPCs verliehen, da er \u00fcber eine au\u00dfergew\u00f6hnliche F\u00e4higkeit verf\u00fcgt, bei Patienten mit Becker-Muskeldystrophie (BMD) neue Muskeln mit vollst\u00e4ndigem Dystrophin zu produzieren.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">IPS HEART hat nun nachgewiesen, dass GIVI-MPCs in einem Mausmodell mit Sarkopenie, juvenilen und sehr alten Duchenne-Muskeldystrophie-M\u00e4usen (DMD) und dystrophen Schweinen neue menschliche Muskeln mit menschlichem Dystrophin in voller L\u00e4nge produzieren. Um das au\u00dfergew\u00f6hnliche Plattformpotenzial von GIVI-MPCs zur Umkehrung schw\u00e4chender Krankheiten zu demonstrieren, hat das FDA GIVI-MPCs zuvor den Orphan-Drug-Status f\u00fcr DMD verliehen.<\/p>","protected":false},"excerpt":{"rendered":"<p>The FDA has granted IPS HEART Orphan Drug Designation (ODD) for GIVI-MPCs because of its exceptional capacity to produce new muscle with full length dystrophin in patients with Becker Muscular Dystrophy (BMD). It has now been demonstrated by IPS HEART that GIVI-MPCs produce new human muscle with full length human dystrophin in a mouse model [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2441,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[67,73,88,160,161],"class_list":["post-2438","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-becker-muscular-dystrophy","tag-dystrophin","tag-fda","tag-givi-mpc","tag-ips-heart"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/posts\/2438","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/comments?post=2438"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/posts\/2438\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/media\/2441"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/media?parent=2438"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/categories?post=2438"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/de\/wp-json\/wp\/v2\/tags?post=2438"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}