{"id":8854,"date":"2026-10-14T11:55:39","date_gmt":"2026-10-14T08:55:39","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=8854"},"modified":"2026-10-14T11:55:43","modified_gmt":"2026-10-14T08:55:43","slug":"sapreme-therapeutics-spm-2551-dystrophin-restoration-duchenne","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ar\/sapreme-therapeutics-spm-2551-dystrophin-restoration-duchenne\/","title":{"rendered":"\u0623\u0638\u0647\u0631\u062a \u062f\u0631\u0627\u0633\u0629 Sapreme Therapeutics \u062a\u062d\u0633\u0646\u0627\u064b \u0645\u0644\u062d\u0648\u0638\u0627\u064b \u0641\u064a \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0641\u064a \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 SPM-2551 \u0641\u064a \u0639\u0644\u0627\u062c \u062f\u0648\u0634\u064a\u0646."},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>\u0623\u0639\u0644\u0646\u062a \u0634\u0631\u0643\u0629 Sapreme Therapeutics \u0639\u0646 \u0646\u062a\u0627\u0626\u062c \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0648\u0627\u0639\u062f\u0629 \u0644\u0640 SPM-2551\u060c \u0648\u0647\u0648 \u0639\u0644\u0627\u062c \u062a\u062c\u0631\u064a\u0628\u064a \u0644\u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a (\u062f\u0648\u0634\u064a\u0646) \u064a\u0633\u062a\u062e\u062f\u0645 \u062a\u0642\u0646\u064a\u0629 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 \u0648\u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0642\u0627\u0626\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0631\u064a\u0628\u064a\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0642\u0644\u064a\u0644 \u0627\u0644\u0646\u0648\u0643\u0644\u064a\u0648\u062a\u064a\u062f\u0627\u062a \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u062d\u0633\u0627\u0633\u064a\u0629 (ASOs).<\/strong> \u0639\u0631\u0636\u062a \u0627\u0644\u0634\u0631\u0643\u0629 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0641\u064a \u0627\u0644\u0627\u062c\u062a\u0645\u0627\u0639 \u0627\u0644\u0633\u0646\u0648\u064a \u0627\u0644\u062b\u0627\u0646\u064a \u0648\u0627\u0644\u0639\u0634\u0631\u064a\u0646 \u0644\u062c\u0645\u0639\u064a\u0629 \u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0623\u0648\u0644\u064a\u063a\u0648\u0646\u0648\u0643\u0644\u064a\u0648\u062a\u064a\u062f (OTS) 2026. \u0648\u0623\u0638\u0647\u0631\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0632\u064a\u0627\u062f\u0627\u062a \u0643\u0628\u064a\u0631\u0629 \u0641\u064a \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0628\u0639\u062f \u062c\u0631\u0639\u0629 \u0645\u0646\u062e\u0641\u0636\u0629 \u0648\u0627\u062d\u062f\u0629 \u0641\u064a \u0646\u0645\u0648\u0630\u062c \u062f\u0648\u0634\u064a\u0646 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a.<\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>\u062c\u062f\u0648\u0644 \u0627\u0644\u0645\u062d\u062a\u0648\u064a\u0627\u062a<\/h2><nav><ul><li><a href=\"#how-does-spm-2551-work\">\u0643\u064a\u0641 \u064a\u0639\u0645\u0644 \u062c\u0647\u0627\u0632 SPM-2551\u061f<\/a><\/li><li><a href=\"#dystrophin-increased-to-more-than-35-and-55-of-normal-levels\">\u0627\u0631\u062a\u0641\u0639 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0625\u0644\u0649 \u0623\u0643\u062b\u0631 \u0645\u0646 35% \u0648 55% \u0645\u0646 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629<\/a><\/li><li><a href=\"#when-will-human-trials-begin\">\u0645\u062a\u0649 \u0633\u062a\u0628\u062f\u0623 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631\u061f<\/a><\/li><li><a href=\"#what-do-these-results-mean-for-duchenne\">\u0645\u0627\u0630\u0627 \u062a\u0639\u0646\u064a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646\u061f<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<h2 id=\"how-does-spm-2551-work\" class=\"wp-block-heading\">\u0643\u064a\u0641 \u064a\u0639\u0645\u0644 \u062c\u0647\u0627\u0632 SPM-2551\u061f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u064a\u0646\u062a\u062c \u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646 \u0639\u0646 \u062a\u063a\u064a\u0631\u0627\u062a \u062c\u064a\u0646\u064a\u0629 \u062a\u0645\u0646\u0639 \u0627\u0644\u062c\u0633\u0645 \u0645\u0646 \u0625\u0646\u062a\u0627\u062c \u0643\u0645\u064a\u0629 \u0643\u0627\u0641\u064a\u0629 \u0645\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0627\u0644\u0648\u0638\u064a\u0641\u064a\u060c \u0648\u0647\u0648 \u0628\u0631\u0648\u062a\u064a\u0646 \u0636\u0631\u0648\u0631\u064a \u0644\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0642\u0648\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0648\u0628\u0646\u064a\u062a\u0647\u0627.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u064a\u062c\u0645\u0639 SPM-2551 \u0628\u064a\u0646 \u062b\u0644\u0627\u062b\u0629 \u0645\u0643\u0648\u0646\u0627\u062a: \u062c\u0633\u0645 \u0645\u0636\u0627\u062f \u064a\u0633\u062a\u0647\u062f\u0641 \u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a\u060c \u0648\u0623\u0648\u0644\u064a\u063a\u0648\u0646\u0648\u0643\u0644\u064a\u0648\u062a\u064a\u062f \u0645\u0636\u0627\u062f \u0644\u0644\u062c\u064a\u0646 \u0645\u0635\u0645\u0645 \u0644\u0644\u0645\u0633\u0627\u0639\u062f\u0629 \u0641\u064a \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646\u060c \u0648\u062a\u0642\u0646\u064a\u0629 SPT \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0634\u0631\u0643\u0629 Sapreme.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u062a\u0647\u062f\u0641 \u062a\u0642\u0646\u064a\u0629 SPT \u0625\u0644\u0649 \u062d\u0644 \u062a\u062d\u062f\u064d\u0651 \u0631\u0626\u064a\u0633\u064a \u064a\u0648\u0627\u062c\u0647 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0642\u0627\u0626\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0631\u064a\u0628\u064a (RNA). \u0641\u0628\u0639\u062f \u062f\u062e\u0648\u0644\u0647\u0627 \u0627\u0644\u062e\u0644\u064a\u0629\u060c \u0642\u062f \u062a\u064f\u062d\u0627\u0635\u0631 \u0647\u0630\u0647 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u062f\u0627\u062e\u0644 \u062a\u0631\u0627\u0643\u064a\u0628 \u0635\u063a\u064a\u0631\u0629 \u062a\u064f\u0633\u0645\u0649 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0627\u0644\u062f\u0627\u062e\u0644\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u0645\u0646\u0639\u0647\u0627 \u0645\u0646 \u0627\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u0649 \u0647\u062f\u0641\u0647\u0627 \u0627\u0644\u0645\u0646\u0634\u0648\u062f. \u0635\u064f\u0645\u0645\u062a \u062a\u0642\u0646\u064a\u0629 Sapreme \u0644\u0645\u0633\u0627\u0639\u062f\u0629 \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u062f\u0648\u0627\u0621 \u0639\u0644\u0649 \u0627\u0644\u062e\u0631\u0648\u062c \u0645\u0646 \u0647\u0630\u0647 \u0627\u0644\u062a\u0631\u0627\u0643\u064a\u0628 \u0648\u0627\u0644\u0639\u0645\u0644 \u062f\u0627\u062e\u0644 \u0627\u0644\u062e\u0644\u064a\u0629.<\/p>\n\n\n\n<h2 id=\"dystrophin-increased-to-more-than-35-and-55-of-normal-levels\" class=\"wp-block-heading\">\u0627\u0631\u062a\u0641\u0639 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0625\u0644\u0649 \u0623\u0643\u062b\u0631 \u0645\u0646 35% \u0648 55% \u0645\u0646 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0648\u062c\u0627\u0621\u062a \u0623\u0628\u0631\u0632 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u0646 \u0646\u0645\u0648\u0630\u062c \u0641\u0623\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0628\u0634\u0631\u064a \u0627\u0644\u0630\u064a \u062a\u0645 \u062a\u0637\u0648\u064a\u0631\u0647 \u0641\u064a \u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631\u0629 \u0623\u0646\u064a\u0645\u064a\u0643 \u0622\u0631\u062a\u0633\u0645\u0627-\u0631\u0648\u0633.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u062d\u0642\u0642 SPM-2551 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 \u0628\u0645\u0642\u062f\u0627\u0631 5-10 \u0623\u0636\u0639\u0627\u0641 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0646\u064a\u0648\u0643\u0644\u064a\u0648\u062a\u064a\u062f\u0627\u062a \u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629\u060c \u062d\u062a\u0649 \u0639\u0646\u062f \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062c\u0631\u0639\u0629 \u0645\u0646 \u0627\u0644\u0646\u064a\u0648\u0643\u0644\u064a\u0648\u062a\u064a\u062f\u0627\u062a \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u062d\u0633\u0627\u0633\u064a\u0629 \u0623\u0642\u0644 \u0628\u062d\u0648\u0627\u0644\u064a \u0639\u0634\u0631 \u0645\u0631\u0627\u062a.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0648\u0643\u0627\u0646\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0645\u0634\u062c\u0639\u0629 \u0628\u0634\u0643\u0644 \u062e\u0627\u0635:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0639\u0646\u062f \u062c\u0631\u0639\u0629 1 \u0645\u0644\u063a\u0645\/\u0643\u063a\u0645: \u0648\u0635\u0644 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0625\u0644\u0649 \u0623\u0643\u062b\u0631 \u0645\u0646 35% \u0645\u0646 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629.<\/li>\n\n\n\n<li>\u0639\u0646\u062f \u062c\u0631\u0639\u0629 3 \u0645\u0644\u063a\/\u0643\u063a: \u0648\u0635\u0644 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0625\u0644\u0649 \u0623\u0643\u062b\u0631 \u0645\u0646 55% \u0645\u0646 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u062a\u0645 \u0642\u064a\u0627\u0633 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0628\u0639\u062f 56 \u064a\u0648\u0645\u064b\u0627 \u0645\u0646 \u062a\u0646\u0627\u0648\u0644 \u062c\u0631\u0639\u0629 \u0648\u0627\u062d\u062f\u0629. \u0648\u062a\u0634\u064a\u0631 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0625\u0644\u0649 \u0623\u0646 \u0627\u0644\u062c\u0631\u0639\u0627\u062a \u0627\u0644\u0623\u0639\u0644\u0649 \u0623\u062f\u062a \u0625\u0644\u0649 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0623\u0643\u0628\u0631 \u0644\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646\u060c \u0648\u0623\u0646 \u0647\u0630\u0627 \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0633\u062a\u0645\u0631 \u0637\u0648\u0627\u0644 \u0641\u062a\u0631\u0629 \u0627\u0644\u0645\u0644\u0627\u062d\u0638\u0629.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0623\u0639\u0644\u0646\u062a \u0634\u0631\u0643\u0629 \u0633\u0627\u0628\u0631\u064a\u0645 \u0623\u0646 \u0647\u062f\u0641\u0647\u0627 \u0627\u0644\u062a\u0637\u0648\u064a\u0631\u064a \u0647\u0648 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0625\u0644\u0649 \u0623\u0643\u062b\u0631 \u0645\u0646 15% \u0645\u0646 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629. \u0648\u0642\u062f \u062a\u062c\u0627\u0648\u0632\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0645\u064f\u0628\u0644\u063a \u0639\u0646\u0647\u0627 \u0647\u0630\u0627 \u0627\u0644\u0647\u062f\u0641 \u0639\u0646\u062f \u0643\u0644\u062a\u0627 \u0627\u0644\u062c\u0631\u0639\u062a\u064a\u0646 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u062a\u064a\u0646. \u0645\u0639 \u0630\u0644\u0643\u060c \u0641\u0625\u0646 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u0633\u062a\u0645\u062f\u0629 \u0645\u0646 \u0646\u0645\u0648\u0630\u062c \u062d\u064a\u0648\u0627\u0646\u064a\u060c \u0648\u0644\u0627 \u062a\u064f\u062d\u062f\u062f \u0645\u062f\u0649 \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0644\u062f\u0649 \u0627\u0644\u0628\u0634\u0631.<\/p>\n\n\n\n<h2 id=\"when-will-human-trials-begin\" class=\"wp-block-heading\">\u0645\u062a\u0649 \u0633\u062a\u0628\u062f\u0623 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631\u061f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u062a\u0633\u062a\u0639\u062f \u0634\u0631\u0643\u0629 Sapreme \u0644\u0625\u062c\u0631\u0627\u0621 \u062f\u0631\u0627\u0633\u0627\u062a \u062a\u0645\u0643\u064a\u0646\u064a\u0629 \u0644\u0640 SPM-2551 \u0641\u064a \u0639\u0627\u0645 2027.<\/strong> \u062a\u0647\u062f\u0641 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0625\u0644\u0649 \u062a\u0648\u0644\u064a\u062f \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0644\u0627\u0632\u0645\u0629 \u0644\u062f\u0639\u0645 \u0637\u0644\u0628 \u0645\u062d\u062a\u0645\u0644 \u0644\u0628\u062f\u0621 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0644\u0645 \u062a\u0639\u0644\u0646 \u0627\u0644\u0634\u0631\u0643\u0629 \u0639\u0646 \u062a\u0627\u0631\u064a\u062e \u0645\u062d\u062f\u062f \u0644\u0628\u062f\u0621 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631.<\/strong> \u062a\u062a\u0645\u062b\u0644 \u062e\u0637\u062a\u0647\u0627 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u0641\u064a \u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0645\u0631\u0634\u062d \u0646\u062d\u0648 \u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u060c \u0628\u062f\u0621\u064b\u0627 \u0645\u0646 \u0627\u0644\u062a\u062d\u0636\u064a\u0631\u0627\u062a \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0644\u0627\u0632\u0645\u0629.<\/p>\n\n\n\n<h2 id=\"what-do-these-results-mean-for-duchenne\" class=\"wp-block-heading\">\u0645\u0627\u0630\u0627 \u062a\u0639\u0646\u064a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646\u061f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0623\u0638\u0647\u0631 \u0627\u0644\u0645\u0631\u0643\u0628 SPM-2551 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0645\u0644\u062d\u0648\u0638\u0629 \u0644\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0628\u0639\u062f \u062c\u0631\u0639\u0629 \u0645\u0646\u062e\u0641\u0636\u0629 \u0648\u0627\u062d\u062f\u0629 \u0641\u064a \u0646\u0645\u0648\u0630\u062c \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a. \u0648\u0642\u062f \u062a\u0633\u0627\u0639\u062f \u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u0645\u0648\u062c\u0647 \u0648\u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u0647\u0631\u0648\u0628 \u0645\u0646 \u0627\u0644\u062c\u0633\u064a\u0645\u0627\u062a \u0627\u0644\u062f\u0627\u062e\u0644\u064a\u0629 \u0639\u0644\u0649 \u062a\u062d\u0642\u064a\u0642 \u0627\u0644\u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0628\u062c\u0631\u0639\u0627\u062a \u0623\u0642\u0644 \u0648\u0641\u062a\u0631\u0627\u062a \u0632\u0645\u0646\u064a\u0629 \u0623\u0637\u0648\u0644 \u0628\u064a\u0646 \u0627\u0644\u062c\u0631\u0639\u0627\u062a.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u062a\u062a\u0645\u062b\u0644 \u0627\u0644\u062e\u0637\u0648\u0629 \u0627\u0644\u0645\u0647\u0645\u0629 \u0627\u0644\u062a\u0627\u0644\u064a\u0629 \u0641\u064a \u062a\u062d\u062f\u064a\u062f \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0628\u0627\u0644\u0625\u0645\u0643\u0627\u0646 \u062a\u0643\u0631\u0627\u0631 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0628\u0623\u0645\u0627\u0646 \u0648\u0641\u0639\u0627\u0644\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631. \u0625\u0644\u0649 \u062d\u064a\u0646 \u062a\u0642\u062f\u064a\u0645 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0647\u0630\u0627 \u0627\u0644\u062f\u0644\u064a\u0644\u060c \u064a\u0628\u0642\u0649 \u0639\u0642\u0627\u0631 SPM-2551 \u0639\u0644\u0627\u062c\u064b\u0627 \u062a\u062c\u0631\u064a\u0628\u064a\u064b\u0627\u060c \u0648\u0644\u0645 \u062a\u064f\u062b\u0628\u062a \u0628\u0639\u062f \u0641\u0648\u0627\u0626\u062f\u0647 \u0627\u0644\u0645\u062d\u062a\u0645\u0644\u0629 \u0644\u0644\u0623\u0634\u062e\u0627\u0635 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0627\u0643\u062a\u0634\u0641 \u0627\u0644\u0645\u0632\u064a\u062f<\/strong>:\u00a0<a href=\"https:\/\/dmdwarrior.com\/clinical-trials\/map\/\" target=\"_blank\" rel=\"noopener\">\u062e\u0631\u064a\u0637\u0629 \u0645\u0648\u0627\u0642\u0639 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>","protected":false},"excerpt":{"rendered":"<p>Sapreme Therapeutics has announced promising preclinical results for SPM-2551, an experimental treatment for Duchenne muscular dystrophy (Duchenne) that uses exon-skipping technology and RNA-based medicines, including antisense oligonucleotides (ASOs). The company presented the new findings at the 22nd Annual Meeting of the Oligonucleotide Therapeutics Society (OTS) 2026. The results showed substantial increases in dystrophin production following [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":8855,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[929,77,931,930,928,932,927],"class_list":["post-8854","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-dystrophin-restoration","tag-exon-skipping","tag-oligonucleotide-therapeutics","tag-rna-therapeutics","tag-sapreme-therapeutics","tag-sirna","tag-spm-2551"],"subtitle":"\u062d\u0642\u0642 \u0627\u0644\u0645\u0631\u0643\u0628 SPM-2551 (Sapreme Therapeutics) \u0632\u064a\u0627\u062f\u0629 \u0645\u0644\u062d\u0648\u0638\u0629 \u0641\u064a \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0641\u064a \u0646\u0645\u0648\u0630\u062c \u062f\u0648\u0634\u064a\u0646. \u0639\u0646\u062f \u062c\u0631\u0639\u0627\u062a 1 \u06483 \u0645\u0644\u063a\u0645\/\u0643\u063a\u0645\u060c \u062a\u062c\u0627\u0648\u0632\u062a \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629 35% \u064855% \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a. \u0647\u0644 \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0647\u0630\u0627 \u0627\u0644\u0646\u0647\u062c \u0627\u0644\u0642\u0627\u0626\u0645 \u0639\u0644\u0649 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 \u062c\u0627\u0647\u0632\u064b\u0627 \u0644\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631 \u0641\u064a \u0639\u0627\u0645 2027\u061f","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/8854","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/comments?post=8854"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/8854\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media\/8855"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media?parent=8854"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/categories?post=8854"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/tags?post=8854"}],"curies":[{"name":"\u0648\u0648\u0631\u062f\u0628\u0631\u064a\u0633","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}