{"id":5512,"date":"2026-01-31T12:29:03","date_gmt":"2026-01-31T09:29:03","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=5512"},"modified":"2026-01-31T13:15:17","modified_gmt":"2026-01-31T10:15:17","slug":"sonothera-ripple-ultrasound-mediated-delivery-full-length-human-dystrophin","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ar\/sonothera-ripple-ultrasound-mediated-delivery-full-length-human-dystrophin\/","title":{"rendered":"\u062a\u0642\u0646\u064a\u0629 RIPPLE \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0640 SonoThera \u062a\u064f\u0639\u0637\u064a \u0627\u0644\u0623\u0645\u0644 \u0641\u064a \u0625\u0646\u062a\u0627\u062c \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0628\u0634\u0631\u064a \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u0623\u0639\u0644\u0646\u062a \u0634\u0631\u0643\u0629 SonoThera\u060c \u0648\u0647\u064a \u0634\u0631\u0643\u0629 \u0644\u0644\u062a\u0643\u0646\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0645\u0643\u0631\u0633\u0629 \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0623\u0633\u0628\u0627\u0628 \u0627\u0644\u062c\u0630\u0631\u064a\u0629 \u0644\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u062c\u064a\u0644 \u0627\u0644\u062a\u0627\u0644\u064a \u0645\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629\u060c \u0641\u064a 8 \u064a\u0646\u0627\u064a\u0631 2026\u060c \u0623\u0646 \u062a\u0642\u0646\u064a\u0629 RIPPLE\u2122 \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0647\u0627 \u0642\u062f \u0627\u0643\u062a\u0634\u0641\u062a \u062a\u0639\u0628\u064a\u0631\u064b\u0627 \u0642\u0648\u064a\u064b\u0627 \u0648\u0645\u0633\u062a\u0645\u0631\u064b\u0627 \u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0627\u0644\u0628\u0634\u0631\u064a \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644 \u0641\u064a \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0647\u064a\u0643\u0644\u064a\u0629 \u0644\u0644\u0631\u0626\u064a\u0633\u064a\u0627\u062a \u063a\u064a\u0631 \u0627\u0644\u0628\u0634\u0631\u064a\u0629\u060c \u0644\u064a\u0635\u0644 \u0625\u0644\u0649 290% \u0645\u0646 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629.<\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>\u062c\u062f\u0648\u0644 \u0627\u0644\u0645\u062d\u062a\u0648\u064a\u0627\u062a<\/h2><nav><ul><li><a href=\"#sono-theras-nonviral-platform-ripple\">\u0645\u0646\u0635\u0629 SonoThera \u063a\u064a\u0631 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u064a\u0629: RIPPLE<\/a><\/li><li><a href=\"#datas-of-full-length-human-dystrophin-raises-expectations\">\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0627\u0644\u0628\u0634\u0631\u064a \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644 \u062a\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u062a\u0648\u0642\u0639\u0627\u062a<\/a><\/li><li><a href=\"#questions-we-asked-sono-thera-and-their-answers\">\u0627\u0644\u0623\u0633\u0626\u0644\u0629 \u0627\u0644\u062a\u064a \u0637\u0631\u062d\u0646\u0627\u0647\u0627 \u0639\u0644\u0649 SonoThera \u0648\u0627\u0644\u0625\u062c\u0627\u0628\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0644\u0642\u064a\u0646\u0627\u0647\u0627<\/a><ul><li><a href=\"#in-your-press-release-you-mentioned-conducting-a-study-on-non-human-primates-in-this-study-which-genetic-medicine-did-you-use-to-deliver-to-organs-using-umd-technology\">\u0630\u0643\u0631\u062a \u0627\u0644\u0634\u0631\u0643\u0629 \u0641\u064a \u0628\u064a\u0627\u0646\u0647\u0627 \u0627\u0644\u0635\u062d\u0641\u064a SonoThera \u0623\u0646\u0647\u0627 \u0623\u062c\u0631\u062a \u062f\u0631\u0627\u0633\u0629 \u0639\u0644\u0649 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0627\u062a \u063a\u064a\u0631 \u0627\u0644\u0628\u0634\u0631\u064a\u0629. \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629\u060c \u0645\u0627 \u0647\u0648 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0630\u064a \u0627\u0633\u062a\u062e\u062f\u0645\u062a\u0647 \u0627\u0644\u0634\u0631\u0643\u0629 \u0644\u0625\u064a\u0635\u0627\u0644\u0647 \u0625\u0644\u0649 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062a\u0642\u0646\u064a\u0629 UMD\u061f<\/a><\/li><li><a href=\"#to-confirm-we-ask-are-you-using-a-genetic-medicine-developed-in-house-by-sono-thera-using-umd-that-is-not-a-gene-therapy-that-is-already-on-the-market-or-undergoing-clinical-trials-are-you-using-a-gene-medicine-that-is-entirely-owned-by-sono-thera\">\u0648\u0644\u0644\u062a\u0623\u0643\u064a\u062f\u060c \u0646\u0633\u0623\u0644: \u0647\u0644 \u062a\u0633\u062a\u062e\u062f\u0645 \u0634\u0631\u0643\u0629 SonoThera \u062f\u0648\u0627\u0621\u064b \u062c\u064a\u0646\u064a\u0627\u064b \u062a\u0645 \u062a\u0637\u0648\u064a\u0631\u0647 \u062f\u0627\u062e\u0644\u064a\u0627\u064b\u061f \u0623\u064a \u0644\u064a\u0633 \u0639\u0644\u0627\u062c\u0627\u064b \u062c\u064a\u0646\u064a\u0627\u064b \u0645\u0648\u062c\u0648\u062f\u0627\u064b \u0628\u0627\u0644\u0641\u0639\u0644 \u0641\u064a \u0627\u0644\u0633\u0648\u0642 \u0623\u0648 \u064a\u062e\u0636\u0639 \u0644\u062a\u062c\u0627\u0631\u0628 \u0633\u0631\u064a\u0631\u064a\u0629!<\/a><\/li><li><a href=\"#which-tests-were-used-to-determine-if-full-length-dystrophin-production-was-achieved-did-you-measure-it-via-muscle-biopsy\">\u0645\u0627 \u0647\u064a \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u062a\u064a \u0627\u0633\u062a\u064f\u062e\u062f\u0645\u062a \u0644\u062a\u062d\u062f\u064a\u062f \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0642\u062f \u062a\u0645 \u0625\u0646\u062a\u0627\u062c \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644\u061f \u0647\u0644 \u0642\u0627\u0645 SonoThera \u0628\u0642\u064a\u0627\u0633\u0647 \u0639\u0646 \u0637\u0631\u064a\u0642 \u062e\u0632\u0639\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a\u061f<\/a><\/li><li><a href=\"#did-you-have-the-opportunity-to-see-the-creatine-kinase-ast-and-alt-results-how-much-did-these-values-decrease\">\u0647\u0644 \u0623\u062a\u064a\u062d\u062a \u0627\u0644\u0641\u0631\u0635\u0629 \u0644\u0640 SonoThera \u0644\u0644\u0627\u0637\u0644\u0627\u0639 \u0639\u0644\u0649 \u0646\u062a\u0627\u0626\u062c \u0643\u0631\u064a\u0627\u062a\u064a\u0646 \u0643\u064a\u0646\u0627\u0632\u060c \u0648AST\u060c \u0648ALT\u061f \u0645\u0627 \u0645\u0642\u062f\u0627\u0631 \u0627\u0646\u062e\u0641\u0627\u0636 \u0647\u0630\u0647 \u0627\u0644\u0642\u064a\u0645\u061f<\/a><\/li><li><a href=\"#when-do-you-plan-to-begin-studies-on-humans\">\u0645\u062a\u0649 \u062a\u062e\u0637\u0637 \u0634\u0631\u0643\u0629 SonoThera \u0644\u0628\u062f\u0621 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631\u061f<\/a><\/li><\/ul><\/li><li><a href=\"#the-road-to-clinic-trials\">\u0627\u0644\u0637\u0631\u064a\u0642 \u0625\u0644\u0649 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0644\u0645\u0639\u0631\u0641\u0629 \u0627\u0644\u0645\u0632\u064a\u062f \u0639\u0646 \u062a\u0642\u0646\u064a\u0629 RIPPLE \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0640 SonoThera \u0628\u0634\u0643\u0644 \u0645\u0628\u0627\u0634\u0631\u060c \u0627\u062a\u0635\u0644\u0646\u0627 \u0628\u0625\u0644\u064a\u0632\u0627\u0628\u064a\u062b \u0647\u0627\u0631\u0646\u0633 \u0645\u0646 \u0642\u0633\u0645 \u0627\u0644\u0627\u062a\u0635\u0627\u0644\u0627\u062a \u0627\u0644\u0645\u0624\u0633\u0633\u064a\u0629 \u0648\u0634\u0627\u0631\u0643\u0646\u0627 \u0623\u0633\u0626\u0644\u062a\u0646\u0627 \u0646\u064a\u0627\u0628\u0629 \u0639\u0646 \u0645\u062a\u0627\u0628\u0639\u064a\u0646\u0627.<\/strong> \u0642\u062f\u0645\u062a \u0625\u0644\u064a\u0632\u0627\u0628\u064a\u062b \u0628\u062a\u0623\u0646\u064d \u0648\u0634\u0645\u0648\u0644\u064a\u0629 \u062a\u0641\u0627\u0635\u064a\u0644 \u062d\u0648\u0644 \u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u062a\u0648\u0635\u064a\u0644 \u0628\u0648\u0633\u0627\u0637\u0629 \u0627\u0644\u0645\u0648\u062c\u0627\u062a \u0641\u0648\u0642 \u0627\u0644\u0635\u0648\u062a\u064a\u0629 (UMD)\u060c \u0648\u0627\u0644\u062a\u064a \u0645\u0646 \u0627\u0644\u0645\u062e\u0637\u0637 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0647\u0627 \u0623\u064a\u0636\u064b\u0627 \u0641\u064a \u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0623\u0639\u0644\u0646\u062a \u0634\u0631\u0643\u0629 SonoThera\u060c \u0627\u0644\u0645\u062a\u062e\u0635\u0635\u0629 \u0641\u064a \u0627\u0644\u0637\u0628 \u0627\u0644\u062c\u064a\u0646\u064a \u0648\u0645\u0642\u0631\u0647\u0627 \u062c\u0646\u0648\u0628 \u0633\u0627\u0646 \u0641\u0631\u0627\u0646\u0633\u064a\u0633\u0643\u0648\u060c \u0639\u0646 \u0628\u062f\u0621 \u062c\u0648\u0644\u0629 \u062a\u0645\u0648\u064a\u0644 \u0645\u0646 \u0627\u0644\u0641\u0626\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0628\u0642\u064a\u0645\u0629 $125 \u0645\u0644\u064a\u0648\u0646 \u062f\u0648\u0644\u0627\u0631 \u0623\u0645\u0631\u064a\u0643\u064a \u062e\u0644\u0627\u0644 \u0645\u0624\u062a\u0645\u0631 \u062c\u064a \u0628\u064a \u0645\u0648\u0631\u063a\u0627\u0646 \u0644\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0627\u0644\u0631\u0627\u0628\u0639 \u0648\u0627\u0644\u0623\u0631\u0628\u0639\u064a\u0646. \u0648\u0633\u064a\u064f\u0633\u062a\u062e\u062f\u0645 \u0631\u0623\u0633 \u0627\u0644\u0645\u0627\u0644 \u0627\u0644\u0645\u064f\u062c\u0645\u0639 \u0641\u064a \u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631 \u0644\u062b\u0644\u0627\u062b\u0629 \u0628\u0631\u0627\u0645\u062c \u0631\u0627\u0626\u062f\u0629 \u062a\u0633\u062a\u0647\u062f\u0641 \u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a (DMD)\u060c \u0648\u0645\u0631\u0636 \u0627\u0644\u0643\u0644\u0649 \u0645\u062a\u0639\u062f\u062f \u0627\u0644\u0643\u064a\u0633\u0627\u062a \u0627\u0644\u0633\u0627\u0626\u062f (ADPKD)\u060c \u0648\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0623\u0644\u0628\u0648\u0631\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0643\u0631\u0648\u0645\u0648\u0633\u0648\u0645 X (XLAS). <strong>\u0633\u062a\u0633\u062a\u0641\u064a\u062f \u0647\u0630\u0647 \u0627\u0644\u0628\u0631\u0627\u0645\u062c \u0645\u0646 \u0645\u0646\u0635\u0629 RIPPLE \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0634\u0631\u0643\u0629 SonoThera\u060c \u0648\u0647\u064a \u062a\u0642\u0646\u064a\u0629 \u062a\u0648\u0635\u064a\u0644 \u063a\u064a\u0631 \u0641\u064a\u0631\u0648\u0633\u064a\u0629 \u062a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0627\u0644\u0645\u0648\u062c\u0627\u062a \u0641\u0648\u0642 \u0627\u0644\u0635\u0648\u062a\u064a\u0629 \u0645\u0635\u0645\u0645\u0629 \u0644\u0644\u062a\u063a\u0644\u0628 \u0639\u0644\u0649 \u0642\u064a\u0648\u062f \u0627\u0644\u0646\u0648\u0627\u0642\u0644 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u064a\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u0645\u0643\u064a\u0646 \u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u062d\u0645\u0648\u0644\u0629 \u0627\u0644\u0645\u0633\u062a\u0647\u062f\u0641\u0629 \u0648\u063a\u064a\u0631 \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629 \u0639\u0644\u0649 \u0627\u0644\u062d\u062c\u0645 \u0648\u062f\u0639\u0645 \u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0642\u0627\u0628\u0644 \u0644\u0644\u062a\u0637\u0648\u064a\u0631 \u0648\u0627\u0644\u062a\u0643\u0631\u0627\u0631.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"sono-theras-nonviral-platform-ripple\">\u0645\u0646\u0635\u0629 SonoThera \u063a\u064a\u0631 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u064a\u0629: RIPPLE<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u064a\u064f\u0639\u0627\u0644\u062c \u0646\u0647\u062c SonoThera \u0641\u064a \u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0623\u062d\u062f \u0623\u0628\u0631\u0632 \u0627\u0644\u062a\u062d\u062f\u064a\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u0645\u0631\u0629 \u0641\u064a \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a: \u0627\u0644\u0642\u064a\u0648\u062f \u0627\u0644\u0645\u062a\u0623\u0635\u0644\u0629 \u0641\u064a \u0627\u0644\u0646\u0648\u0627\u0642\u0644 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u064a\u0629. \u0641\u0628\u064a\u0646\u0645\u0627 \u0644\u0627 \u064a\u0632\u0627\u0644 \u0627\u0644\u0641\u064a\u0631\u0648\u0633 \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u063a\u062f\u0627\u0646\u064a\u0627\u062a (AAV) \u0647\u0648 \u0627\u0644\u0623\u0633\u0644\u0648\u0628 \u0627\u0644\u0633\u0627\u0626\u062f \u0644\u0644\u062a\u0648\u0635\u064a\u0644\u060c \u0625\u0644\u0627 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\u0627\u0644\u0635\u0648\u062a\u064a\u0629 (UMD)\u060c \u0644\u062a\u062c\u0627\u0648\u0632 \u0647\u0630\u0647 \u0627\u0644\u062d\u0648\u0627\u062c\u0632.<\/strong> \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u062c\u0645\u0639 \u0628\u064a\u0646 \u0627\u0644\u0645\u0648\u062c\u0627\u062a \u0641\u0648\u0642 \u0627\u0644\u0635\u0648\u062a\u064a\u0629 \u0627\u0644\u0645\u0631\u0643\u0632\u0629 \u0648\u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u0641\u0642\u0627\u0639\u0627\u062a \u0627\u0644\u062f\u0642\u064a\u0642\u0629\u060c \u062a\u0632\u064a\u062f \u0647\u0630\u0647 \u0627\u0644\u062a\u0642\u0646\u064a\u0629 \u0645\u0624\u0642\u062a\u064b\u0627 \u0645\u0646 \u0646\u0641\u0627\u0630\u064a\u0629 \u063a\u0634\u0627\u0621 \u0627\u0644\u062e\u0644\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u062a\u064a\u062d \u0627\u0645\u062a\u0635\u0627\u0635\u064b\u0627 \u0645\u0648\u062c\u0647\u064b\u0627 \u0644\u0644\u0645\u0627\u062f\u0629 \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629 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\u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u063a\u064a\u0631 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u064a\u0629 \u0627\u0644\u0645\u062f\u0639\u0648\u0645\u0629 \u0628\u0627\u0644\u0623\u062c\u0647\u0632\u0629\u060c \u0644\u0627 \u0633\u064a\u0645\u0627 \u0645\u0639 \u0627\u0632\u062f\u064a\u0627\u062f \u0627\u0644\u062a\u062f\u0642\u064a\u0642 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a \u0639\u0644\u0649 \u0627\u0644\u0646\u0648\u0627\u0642\u0644 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u064a\u0629 \u0627\u0633\u062a\u062c\u0627\u0628\u0629\u064b \u0644\u0644\u062a\u062d\u062f\u064a\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u0645\u0631\u0629 \u0641\u064a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0648\u0627\u0644\u0633\u0644\u0627\u0645\u0629.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"datas-of-full-length-human-dystrophin-raises-expectations\">\u0628\u064a\u0627\u0646\u0627\u062a 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\u0648\u0631\u063a\u0645 \u0623\u0646 \u0647\u0630\u0647 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u064f\u062e\u062a\u0635\u0631\u0629 \u0642\u062f \u062a\u064f\u0628\u0637\u0626 \u0645\u0646 \u062a\u0637\u0648\u0631 \u0627\u0644\u0645\u0631\u0636\u060c \u0625\u0644\u0627 \u0623\u0646\u0647\u0627 \u0644\u064a\u0633\u062a \u0639\u0644\u0627\u062c\u064a\u0629 \u0648\u0644\u0627 \u062a\u064f\u0639\u064a\u062f \u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0628\u0634\u0643\u0644 \u0643\u0627\u0645\u0644.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629\u060c \u0623\u0628\u0644\u063a\u062a \u062f\u0631\u0627\u0633\u0629 SonoThera \u0639\u0646 \u062a\u0639\u0628\u064a\u0631 \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644 \u0639\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0627\u0644\u0628\u0634\u0631\u064a \u0641\u064a \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0647\u064a\u0643\u0644\u064a\u0629 \u0644\u0644\u0631\u0626\u064a\u0633\u064a\u0627\u062a \u063a\u064a\u0631 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0628\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u062a\u0635\u0644 \u0625\u0644\u0649 290% \u0645\u0646 \u0627\u0644\u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u060c \u0625\u0644\u0649 \u062c\u0627\u0646\u0628 \u0625\u062b\u0628\u0627\u062a \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0642\u0648\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0641\u064a \u0646\u0645\u0627\u0630\u062c \u0627\u0644\u0642\u0648\u0627\u0631\u0636.<\/strong>. \u0625\u0630\u0627 \u0645\u0627 \u062a\u0645 \u062a\u0631\u062c\u0645\u0629 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0648\u0644\u0648 \u062c\u0632\u0626\u064a\u0627\u064b \u0625\u0644\u0649 \u0627\u0644\u0628\u064a\u0626\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629\u060c \u0641\u0642\u062f \u062a\u0645\u062b\u0644 \u062a\u0642\u062f\u0645\u0627\u064b \u062a\u062d\u0648\u064a\u0644\u064a\u0627\u064b \u0641\u064a \u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0634\u064a\u0646\u064a - \u062d\u064a\u062b \u0645\u0646 \u0627\u0644\u0645\u062d\u062a\u0645\u0644 \u0623\u0646 \u062a\u062d\u0642\u0642 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0645\u0646 \u0627\u0644\u0641\u0627\u0626\u062f\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u062a\u0642\u062a\u0631\u0628 \u0645\u0646 \u062a\u0644\u0643 \u0627\u0644\u062a\u064a \u0644\u0648\u062d\u0638\u062a \u0641\u064a \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0628\u064a\u0643\u0631 \u0623\u0648 \u0641\u064a \u062d\u0627\u0645\u0644\u064a \u0637\u0641\u0631\u0629 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0628\u062f\u0648\u0646 \u0623\u0639\u0631\u0627\u0636.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"questions-we-asked-sono-thera-and-their-answers\">\u0627\u0644\u0623\u0633\u0626\u0644\u0629 \u0627\u0644\u062a\u064a \u0637\u0631\u062d\u0646\u0627\u0647\u0627 \u0639\u0644\u0649 SonoThera \u0648\u0627\u0644\u0625\u062c\u0627\u0628\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0644\u0642\u064a\u0646\u0627\u0647\u0627<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"in-your-press-release-you-mentioned-conducting-a-study-on-non-human-primates-in-this-study-which-genetic-medicine-did-you-use-to-deliver-to-organs-using-umd-technology\"><strong>\u0630\u0643\u0631\u062a \u0627\u0644\u0634\u0631\u0643\u0629 \u0641\u064a \u0628\u064a\u0627\u0646\u0647\u0627 \u0627\u0644\u0635\u062d\u0641\u064a SonoThera \u0623\u0646\u0647\u0627 \u0623\u062c\u0631\u062a \u062f\u0631\u0627\u0633\u0629 \u0639\u0644\u0649 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0627\u062a \u063a\u064a\u0631 \u0627\u0644\u0628\u0634\u0631\u064a\u0629. \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629\u060c \u0645\u0627 \u0647\u0648 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0630\u064a \u0627\u0633\u062a\u062e\u062f\u0645\u062a\u0647 \u0627\u0644\u0634\u0631\u0643\u0629 \u0644\u0625\u064a\u0635\u0627\u0644\u0647 \u0625\u0644\u0649 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062a\u0642\u0646\u064a\u0629 UMD\u061f<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u0627\u0644\u0637\u0628 \u0627\u0644\u062c\u064a\u0646\u064a \u0647\u0648 \u0641\u0626\u0629 \u0648\u0627\u0633\u0639\u0629 \u062a\u0634\u0645\u0644 \u0623\u0646\u0648\u0627\u0639\u064b\u0627 \u0639\u062f\u064a\u062f\u0629 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629. <strong>SonoThera \u0647\u064a \u0634\u0631\u0643\u0629 \u0644\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a\u061b \u0648\u0645\u0639 \u0630\u0644\u0643\u060c \u0639\u0644\u0649 \u0639\u0643\u0633 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629 \u062d\u0627\u0644\u064a\u064b\u0627 \u0644\u0645\u0631\u0636 \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0634\u064a\u0646\u064a\u060c \u0641\u0625\u0646\u0646\u0627 \u0644\u0627 \u0646\u0633\u062a\u062e\u062f\u0645 \u0646\u0627\u0642\u0644\u0627\u062a \u062a\u0648\u0635\u064a\u0644 \u0641\u064a\u0631\u0648\u0633\u064a\u0629 \u0645\u062b\u0644 AAV.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0628\u062f\u0644\u0627\u064b \u0645\u0646 \u0630\u0644\u0643\u060c \u0637\u0648\u0631\u062a \u0634\u0631\u0643\u0629 SonoThera \u062d\u0635\u0631\u064a\u0627\u064b \u0645\u0646\u0635\u0629 \u062a\u0648\u0635\u064a\u0644 \u062c\u062f\u064a\u062f\u0629 \u063a\u064a\u0631 \u0641\u064a\u0631\u0648\u0633\u064a\u0629 \u062a\u064f\u0633\u0645\u0649 RIPPLE\u2122. \u0635\u064f\u0645\u0645\u062a RIPPLE\u2122 \u062e\u0635\u064a\u0635\u0627\u064b \u0644\u0644\u062a\u063a\u0644\u0628 \u0639\u0644\u0649 \u0642\u064a\u0648\u062f \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0648\u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0648\u0627\u0644\u062a\u0643\u0644\u0641\u0629\/\u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0641\u064a \u0623\u0633\u0627\u0644\u064a\u0628 \u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062d\u0627\u0644\u064a\u0629.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u064a\u064f\u0645\u0643\u0651\u0646 \u0646\u0647\u062c\u0646\u0627 \u0627\u0644\u062e\u0627\u0635 \u0645\u0646 \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0627\u0644\u062d\u064a\u0648\u064a \u0627\u0644\u0622\u0645\u0646 \u0648\u0627\u0644\u0641\u0639\u0627\u0644 \u0648\u0627\u0644\u0645\u0648\u062d\u062f \u0644\u0644\u062d\u0645\u0648\u0644\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0641\u064a \u062c\u0645\u064a\u0639 \u0623\u0646\u062d\u0627\u0621 \u0627\u0644\u0639\u0636\u0648 \u0627\u0644\u0645\u0633\u062a\u0647\u062f\u0641. <strong>\u0641\u064a \u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a\u060c \u064a\u0646\u0635\u0628 \u062a\u0631\u0643\u064a\u0632\u0646\u0627 \u0639\u0644\u0649 \u062a\u0648\u0635\u064a\u0644 \u062c\u0632\u064a\u0621 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0630\u064a \u064a\u0634\u0641\u0631 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644 \u0625\u0644\u0649 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0647\u064a\u0643\u0644\u064a\u0629 \u0648\u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u062d\u062c\u0627\u0628 \u0627\u0644\u062d\u0627\u062c\u0632\u060c \u0645\u0639 \u062a\u0642\u0644\u064a\u0644 \u062e\u0637\u0631 \u0627\u0644\u062a\u0648\u0635\u064a\u0644 \u063a\u064a\u0631 \u0627\u0644\u0645\u0633\u062a\u0647\u062f\u0641.<\/strong> \u0646\u0638\u0631\u064b\u0627 \u0644\u0623\u0646 \u062a\u0642\u0646\u064a\u0629 RIPPLE\u2122 \u063a\u064a\u0631 \u0641\u064a\u0631\u0648\u0633\u064a\u0629\u060c \u0641\u0647\u064a \u062a\u062a\u0645\u064a\u0632 \u0628\u0642\u062f\u0631\u062a\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u062a\u062e\u0641\u064a \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0648\u062a\u062e\u062a\u0644\u0641 \u0627\u062e\u062a\u0644\u0627\u0641\u064b\u0627 \u062c\u0648\u0647\u0631\u064a\u064b\u0627 \u0639\u0646 \u0645\u0646\u0635\u0627\u062a \u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u0629 \u0641\u064a \u0639\u0644\u0627\u062c\u0627\u062a \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0634\u064a\u0646\u064a \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629. \u0643\u0645\u0627 \u0635\u064f\u0645\u0645\u062a \u0647\u0630\u0647 \u0627\u0644\u062a\u0642\u0646\u064a\u0629 \u0644\u062a\u0643\u0648\u0646 \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0623\u0645\u062f \u0648\u0642\u0627\u0628\u0644\u0629 \u0644\u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u062a\u0633\u062a\u062e\u062f\u0645 \u062a\u0642\u0646\u064a\u0629 RIPPLE\u2122 \u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u0645\u0648\u062c\u0627\u062a \u0641\u0648\u0642 \u0627\u0644\u0635\u0648\u062a\u064a\u0629 \u0648\u0627\u0644\u0645\u062c\u0633\u0627\u062a \u0648\u0627\u0644\u0641\u0642\u0627\u0639\u0627\u062a \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0627\u0644\u0645\u062a\u0648\u0641\u0631\u0629 \u062a\u062c\u0627\u0631\u064a\u0627\u064b \u0644\u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u062d\u0645\u0648\u0644\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0628\u0637\u0631\u064a\u0642\u0629 \u063a\u064a\u0631 \u062c\u0631\u0627\u062d\u064a\u0629.<\/strong> \u064a\u062a\u0645 \u062d\u0642\u0646 \u0627\u0644\u0641\u0642\u0627\u0639\u0627\u062a \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0648\u0627\u0644\u062d\u0645\u0648\u0644\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0645\u0639\u064b\u0627 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0648\u0631\u064a\u062f\u060c \u0648\u062a\u0646\u062a\u0634\u0631 \u0641\u064a \u062c\u0645\u064a\u0639 \u0623\u0646\u062d\u0627\u0621 \u0627\u0644\u062c\u0633\u0645. \u062b\u0645 \u064a\u062a\u0645 \u062a\u0637\u0628\u064a\u0642 \u0637\u0627\u0642\u0629 \u0627\u0644\u0645\u0648\u062c\u0627\u062a \u0641\u0648\u0642 \u0627\u0644\u0635\u0648\u062a\u064a\u0629 \u0628\u0634\u0643\u0644 \u0645\u062d\u062f\u062f \u0639\u0644\u0649 \u0627\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u0645\u0633\u062a\u0647\u062f\u0641\u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0627\u0646\u0647\u064a\u0627\u0631 \u0627\u0644\u0641\u0642\u0627\u0639\u0627\u062a \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0648\u062a\u0643\u0648\u064a\u0646 \u0645\u0633\u0627\u0645 \u0645\u0624\u0642\u062a\u0629. <strong>\u0648\u0647\u0630\u0627 \u064a\u0633\u0645\u062d \u0644\u0644\u062d\u0645\u0648\u0644\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0628\u0627\u0644\u062e\u0631\u0648\u062c \u0645\u0646 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629\u060c \u0648\u0627\u0644\u062f\u062e\u0648\u0644 \u0625\u0644\u0649 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0639\u0636\u0644\u0627\u062a\u060c \u0648\u0627\u0644\u0648\u0635\u0648\u0644 \u0644\u0627\u062d\u0642\u064b\u0627 \u0625\u0644\u0649 \u0627\u0644\u0646\u0648\u0627\u0629\u060c \u062d\u064a\u062b \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u062d\u062f\u062b \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a.<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"to-confirm-we-ask-are-you-using-a-genetic-medicine-developed-in-house-by-sono-thera-using-umd-that-is-not-a-gene-therapy-that-is-already-on-the-market-or-undergoing-clinical-trials-are-you-using-a-gene-medicine-that-is-entirely-owned-by-sono-thera\"><strong>\u0648\u0644\u0644\u062a\u0623\u0643\u064a\u062f\u060c \u0646\u0633\u0623\u0644: \u0647\u0644 \u062a\u0633\u062a\u062e\u062f\u0645 \u0634\u0631\u0643\u0629 SonoThera \u062f\u0648\u0627\u0621\u064b \u062c\u064a\u0646\u064a\u0627\u064b \u062a\u0645 \u062a\u0637\u0648\u064a\u0631\u0647 \u062f\u0627\u062e\u0644\u064a\u0627\u064b\u061f \u0623\u064a \u0644\u064a\u0633 \u0639\u0644\u0627\u062c\u0627\u064b \u062c\u064a\u0646\u064a\u0627\u064b \u0645\u0648\u062c\u0648\u062f\u0627\u064b \u0628\u0627\u0644\u0641\u0639\u0644 \u0641\u064a \u0627\u0644\u0633\u0648\u0642 \u0623\u0648 \u064a\u062e\u0636\u0639 \u0644\u062a\u062c\u0627\u0631\u0628 \u0633\u0631\u064a\u0631\u064a\u0629!<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u0637\u0648\u0651\u0631\u062a \u0634\u0631\u0643\u0629 SonoThera \u0645\u0646\u0635\u0629 \u062a\u0648\u0635\u064a\u0644 \u0645\u0628\u062a\u0643\u0631\u0629 \u063a\u064a\u0631 \u0641\u064a\u0631\u0648\u0633\u064a\u0629 \u062a\u064f\u0633\u0645\u0649 RIPPLE\u2122\u060c \u062a\u0633\u062a\u062e\u062f\u0645 \u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u0645\u0648\u062c\u0627\u062a \u0641\u0648\u0642 \u0627\u0644\u0635\u0648\u062a\u064a\u0629 \u0648\u0627\u0644\u0645\u062c\u0633\u0627\u062a \u0648\u0627\u0644\u0641\u0642\u0627\u0639\u0627\u062a \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0627\u0644\u0645\u062a\u0648\u0641\u0631\u0629 \u062a\u062c\u0627\u0631\u064a\u064b\u0627 \u0644\u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u062d\u0645\u0648\u0644\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0628\u0637\u0631\u064a\u0642\u0629 \u063a\u064a\u0631 \u062c\u0631\u0627\u062d\u064a\u0629. \u0648\u0641\u064a\u0645\u0627 \u064a\u062a\u0639\u0644\u0642 \u0628\u0627\u0644\u062d\u0645\u0648\u0644\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0623\u0648 &quot;\u0627\u0644\u0623\u062f\u0648\u064a\u0629&quot;\u060c \u0641\u0625\u0646 \u0646\u0647\u062c\u0646\u0627 \u064a\u0633\u0645\u062d \u0644\u0646\u0627 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0623\u0646\u0648\u0627\u0639 \u0645\u062e\u062a\u0644\u0641\u0629 \u0645\u0646 \u0627\u0644\u062d\u0645\u0648\u0644\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u062f\u0648\u0646 \u0642\u064a\u0648\u062f \u0639\u0644\u0649 \u0627\u0644\u062d\u062c\u0645. <strong>\u0648\u0627\u0644\u0623\u0647\u0645 \u0645\u0646 \u0630\u0644\u0643\u060c \u0623\u0646\u0646\u0627 \u0644\u0627 \u0646\u0633\u062a\u062e\u062f\u0645 \u0646\u0627\u0642\u0644\u0627\u062a \u062a\u0648\u0635\u064a\u0644 \u0641\u064a\u0631\u0648\u0633\u064a\u0629 \u0645\u062b\u0644 AAV\u060c \u0648\u0644\u0647\u0630\u0627 \u0627\u0644\u0633\u0628\u0628 \u0641\u0625\u0646 \u0646\u0647\u062c\u0646\u0627 \u063a\u064a\u0631 \u0641\u064a\u0631\u0648\u0633\u064a.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0641\u064a\u0645\u0627 \u064a\u062a\u0639\u0644\u0642 \u0628\u0627\u0644\u062d\u0645\u0648\u0644\u0629 \u0627\u0644\u062a\u064a \u0646\u0633\u062a\u062e\u062f\u0645\u0647\u0627 \u0644\u062f\u0631\u0627\u0633\u0629 \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0634\u064a\u0646\u064a\u060c \u0641\u0625\u0646\u0646\u0627 \u0646\u0633\u062a\u062e\u062f\u0645 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0644\u0627\u0633\u062a\u0628\u062f\u0627\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627. <strong>\u0647\u0630\u0647 \u0627\u0644\u062d\u0645\u0648\u0644\u0629 \u0648\u0639\u0646\u0627\u0635\u0631\u0647\u0627 \u0645\u0645\u0644\u0648\u0643\u0629 \u0644\u0634\u0631\u0643\u0629 SonoThera.<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"which-tests-were-used-to-determine-if-full-length-dystrophin-production-was-achieved-did-you-measure-it-via-muscle-biopsy\"><strong>\u0645\u0627 \u0647\u064a \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u062a\u064a \u0627\u0633\u062a\u064f\u062e\u062f\u0645\u062a \u0644\u062a\u062d\u062f\u064a\u062f \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0642\u062f \u062a\u0645 \u0625\u0646\u062a\u0627\u062c \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644\u061f \u0647\u0644 \u0642\u0627\u0645 SonoThera \u0628\u0642\u064a\u0627\u0633\u0647 \u0639\u0646 \u0637\u0631\u064a\u0642 \u062e\u0632\u0639\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a\u061f<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0646\u0639\u0645. \u062a\u0645 \u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u0643\u0627\u0645\u0644 \u0639\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062e\u0632\u0639\u0627\u062a \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0645 \u062c\u0645\u0639\u0647\u0627 \u0628\u0639\u062f \u0627\u0644\u0639\u0644\u0627\u062c.<\/strong> \u062a\u0645 \u062a\u062d\u0644\u064a\u0644 \u0647\u0630\u0647 \u0627\u0644\u0639\u064a\u0646\u0627\u062a \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0637\u0631\u0642 \u0645\u062e\u062a\u0628\u0631\u064a\u0629 \u0645\u0636\u0628\u0648\u0637\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u062a\u0642\u0646\u064a\u0629 Western Blot \u0644\u062a\u0623\u0643\u064a\u062f \u0648\u062c\u0648\u062f \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644\u060c \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0627\u0644\u062d\u064a\u0648\u064a \u0644\u0623\u0644\u064a\u0627\u0641 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0648\u0627\u0644\u062a\u0648\u0637\u064a\u0646 \u0627\u0644\u062e\u0644\u0648\u064a \u0627\u0644\u0641\u0631\u0639\u064a \u0627\u0644\u0645\u0646\u0627\u0633\u0628 \u0628\u0645\u0631\u0648\u0631 \u0627\u0644\u0648\u0642\u062a.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"did-you-have-the-opportunity-to-see-the-creatine-kinase-ast-and-alt-results-how-much-did-these-values-decrease\"><strong>\u0647\u0644 \u0623\u062a\u064a\u062d\u062a \u0627\u0644\u0641\u0631\u0635\u0629 \u0644\u0640 SonoThera \u0644\u0644\u0627\u0637\u0644\u0627\u0639 \u0639\u0644\u0649 \u0646\u062a\u0627\u0626\u062c \u0643\u0631\u064a\u0627\u062a\u064a\u0646 \u0643\u064a\u0646\u0627\u0632\u060c \u0648AST\u060c \u0648ALT\u061f \u0645\u0627 \u0645\u0642\u062f\u0627\u0631 \u0627\u0646\u062e\u0641\u0627\u0636 \u0647\u0630\u0647 \u0627\u0644\u0642\u064a\u0645\u061f<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u0644\u0642\u062f \u0642\u0645\u0646\u0627 \u0628\u062a\u0642\u064a\u064a\u0645 AST \u0648 ALT \u0648\u0639\u0644\u0627\u0645\u0627\u062a \u0625\u0636\u0627\u0641\u064a\u0629 \u0644\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629\u060c \u0648\u062d\u062a\u0649 \u0627\u0644\u0622\u0646 \u0644\u0645 \u0646\u0644\u0627\u062d\u0638 \u0623\u064a \u0645\u0634\u0627\u0643\u0644 \u062a\u062a\u0639\u0644\u0642 \u0628\u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0628\u0639\u062f \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0641\u0631\u062f\u064a \u0623\u0648 \u0627\u0644\u0645\u062a\u0643\u0631\u0631 \u0641\u064a \u0646\u0645\u0627\u0630\u062c \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u0627\u062a \u0627\u0644\u0635\u063a\u064a\u0631\u0629 \u0648\u0627\u0644\u0643\u0628\u064a\u0631\u0629.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0646\u062d\u0646 \u062d\u0627\u0644\u064a\u064b\u0627 \u0628\u0635\u062f\u062f \u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0627\u0646\u062e\u0641\u0627\u0636\u0627\u062a \u0641\u064a \u0627\u0644\u0643\u0631\u064a\u0627\u062a\u064a\u0646 \u0643\u064a\u0646\u0627\u0632 (CK) \u0628\u0639\u062f \u0639\u0644\u0627\u062c \u0646\u0645\u0627\u0630\u062c \u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"when-do-you-plan-to-begin-studies-on-humans\"><strong>\u0645\u062a\u0649 \u062a\u062e\u0637\u0637 \u0634\u0631\u0643\u0629 SonoThera \u0644\u0628\u062f\u0621 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0639\u0644\u0649 \u0627\u0644\u0628\u0634\u0631\u061f<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u0646\u062d\u0646 \u0646\u0633\u062a\u0639\u062f \u0644\u0644\u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0633\u0631\u064a\u0631\u064a \u0648\u0646\u0633\u062a\u0647\u062f\u0641 \u0628\u062f\u0621 \u0623\u0648\u0644 \u062a\u062c\u0631\u0628\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0628\u0634\u0631\u064a\u0629 \u0644\u0646\u0627 \u0641\u064a \u0627\u0644\u0646\u0635\u0641 \u0627\u0644\u0623\u0648\u0644 \u0645\u0646 \u0639\u0627\u0645 2027\u060c \u0631\u0647\u0646\u0627\u064b \u0628\u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"the-road-to-clinic-trials\">\u0627\u0644\u0637\u0631\u064a\u0642 \u0625\u0644\u0649 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u062e\u0627\u0631\u062c \u0646\u0637\u0627\u0642 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629\u060c \u0642\u062f \u062a\u064f\u0639\u0632\u0632 \u0627\u0644\u062f\u064a\u0646\u0627\u0645\u064a\u0643\u064a\u0627\u062a \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0627\u0644\u0645\u062a\u0637\u0648\u0631\u0629 \u0645\u0643\u0627\u0646\u0629 SonoThera. \u0648\u0642\u062f \u0628\u062f\u0623 \u0643\u0644 \u0645\u0646 FDA \u0648EMA \u0628\u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0628\u0634\u0643\u0644 \u0623\u0643\u0628\u0631 \u0639\u0644\u0649 \u0627\u0644\u062a\u0637\u0648\u0631\u0627\u062a \u0641\u064a \u062a\u0642\u0646\u064a\u0627\u062a \u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u062c\u064a\u0646\u0627\u062a\u060c \u0644\u0627 \u0633\u064a\u0645\u0627 \u0628\u0639\u062f \u0627\u0644\u0646\u0643\u0633\u0627\u062a \u0627\u0644\u062a\u064a \u0648\u0627\u062c\u0647\u062a\u0647\u0627 \u0627\u0644\u0628\u0631\u0627\u0645\u062c \u0627\u0644\u0642\u0627\u0626\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0627\u0644\u063a\u062f\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 (AAV) \u0648\u062a\u0642\u0627\u0631\u064a\u0631 \u0648\u0641\u064a\u0627\u062a \u0627\u0644\u0645\u0631\u0636\u0649 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062c\u0647\u0627\u0632\u064a\u0629 \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u062c\u0631\u0639\u0629. \u0625\u0646 \u0625\u062b\u0628\u0627\u062a \u0648\u062c\u0648\u062f \u0646\u0647\u062c \u0622\u0645\u0646 \u0648\u063a\u064a\u0631 \u0641\u064a\u0631\u0648\u0633\u064a \u0644\u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u064a\u0633\u0645\u062d \u0628\u062a\u0643\u0631\u0627\u0631 \u0627\u0644\u062c\u0631\u0639\u0627\u062a \u0642\u062f \u064a\u0643\u0648\u0646 \u0644\u0647 \u0622\u062b\u0627\u0631 \u0628\u0639\u064a\u062f\u0629 \u0627\u0644\u0645\u062f\u0649\u060c \u0625\u0630 \u064a\u064f\u0634\u0643\u0644 \u0627\u0644\u062a\u0648\u0642\u0639\u0627\u062a \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0648\u064a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0623\u0643\u0627\u062f\u064a\u0645\u064a\u0629 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u064a\u0629 \u0648\u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0627\u062a \u0627\u0644\u0645\u0646\u0635\u0627\u062a \u0627\u0644\u062a\u062c\u0627\u0631\u064a\u0629 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0645\u062c\u0627\u0644.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0625\u0630\u0627 \u0646\u062c\u062d \u0645\u0634\u0631\u0648\u0639 SonoThera \u0641\u064a \u062a\u062d\u0642\u064a\u0642 \u0648\u0644\u0648 \u062c\u0632\u0621 \u0645\u0646 \u0625\u0645\u0643\u0627\u0646\u0627\u062a\u0647 \u0627\u0644\u062a\u0643\u0646\u0648\u0644\u0648\u062c\u064a\u0629\u060c \u0641\u0642\u062f \u062a\u062a\u062d\u0648\u0644 \u0645\u0646\u0635\u0629 RIPPLE \u0645\u0646 \u0627\u0628\u062a\u0643\u0627\u0631 \u0646\u0627\u0634\u0626 \u0625\u0644\u0649 \u0625\u0637\u0627\u0631 \u0639\u0645\u0644 \u0623\u0633\u0627\u0633\u064a \u0644\u0644\u062c\u064a\u0644 \u0627\u0644\u0642\u0627\u062f\u0645 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u063a\u064a\u0631 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u064a\u0629.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><span style=\"text-decoration: underline;\">\u0625\u0634\u0639\u0627\u0631 \u0647\u0627\u0645 \u0645\u0646 SonoThera \u0644\u0644\u0645\u0631\u0636\u0649 \u0648\u0639\u0627\u0626\u0644\u0627\u062a\u0647\u0645:<\/span><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u064a\u0631\u062c\u0649 \u0627\u0644\u0639\u0644\u0645 \u0628\u0623\u0646 \u0634\u0631\u0643\u0629 SonoThera \u0644\u0627 \u062a\u0642\u0628\u0644 \u0623\u0648 \u062a\u0631\u0627\u062c\u0639 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629 \u0627\u0644\u0634\u062e\u0635\u064a\u0629 \u062a\u062d\u062a \u0623\u064a \u0638\u0631\u0641 \u0645\u0646 \u0627\u0644\u0638\u0631\u0648\u0641. \u0646\u062a\u0644\u0642\u0649 \u0645\u0646 \u062d\u064a\u0646 \u0644\u0622\u062e\u0631 \u0631\u0633\u0627\u0626\u0644 \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0623\u0648 \u0639\u0627\u0626\u0644\u0627\u062a\u0647\u0645 \u0623\u0648 \u0645\u0642\u062f\u0645\u064a \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0630\u064a\u0646 \u064a\u0631\u063a\u0628\u0648\u0646 \u0641\u064a \u0645\u0634\u0627\u0631\u0643\u0629 \u062a\u0641\u0627\u0635\u064a\u0644 \u0637\u0628\u064a\u0629 \u0639\u0644\u0649 \u0623\u0645\u0644 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0629 \u0641\u064a \u062a\u062c\u0631\u0628\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 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\u0630\u0644\u0643 \u0639\u0644\u0646\u064b\u0627 \u0639\u0628\u0631 \u0628\u064a\u0627\u0646 \u0635\u062d\u0641\u064a \u0631\u0633\u0645\u064a \u0648\u0642\u0646\u0648\u0627\u062a \u0627\u0644\u062a\u0648\u0627\u0635\u0644 \u0627\u0644\u0627\u062c\u062a\u0645\u0627\u0639\u064a \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0627\u0644\u0634\u0631\u0643\u0629\u060c \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0631\u0627\u0628\u0637 \u0645\u0628\u0627\u0634\u0631 \u0644\u0642\u0627\u0626\u0645\u0629 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0641\u064a \u0642\u0627\u0639\u062f\u0629 \u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629. \u0646\u0646\u0635\u062d \u0627\u0644\u0642\u0631\u0627\u0621 \u0628\u0634\u062f\u0629 \u0628\u0627\u0644\u0627\u0639\u062a\u0645\u0627\u062f \u0641\u0642\u0637 \u0639\u0644\u0649 \u0647\u0630\u0647 \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0631\u0633\u0645\u064a\u0629 \u0648\u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u062a\u062d\u062f\u064a\u062b\u0627\u062a \u0639\u0628\u0631 \u0645\u0648\u0642\u0639\u0646\u0627 \u0627\u0644\u0625\u0644\u0643\u062a\u0631\u0648\u0646\u064a\u060c \u0648\u062d\u0633\u0627\u0628\u0627\u062a\u0646\u0627 \u0639\u0644\u0649 \u0644\u064a\u0646\u0643\u062f\u0625\u0646\u060c \u0648\u0628\u0644\u0648 \u0633\u0643\u0627\u064a\u060c \u0648\u062a\u0648\u064a\u062a\u0631\/\u0625\u0643\u0633. <a href=\"https:\/\/www.linkedin.com\/company\/sonothera\" target=\"_blank\" rel=\"noreferrer noopener\">\u0644\u064a\u0646\u0643\u062f \u0625\u0646<\/a> | <a href=\"https:\/\/bsky.app\/profile\/sonothera.bsky.social\" target=\"_blank\" rel=\"noreferrer noopener\">\u0628\u0644\u0648 \u0633\u0643\u0627\u064a<\/a> | <a href=\"https:\/\/x.com\/SonotheraI41798\" target=\"_blank\" rel=\"noreferrer noopener\">\u062a\u0648\u064a\u062a\u0631\/\u0625\u0643\u0633<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>SonoThera, a biotechnology company dedicated to treat the root causes of human diseases by developing the next generation of genetic medicines, announced on January 8, 2026, that its proprietary RIPPLE\u2122 technology had detected strong and persistent full-length human dystrophin protein expression in the skeletal muscles of non-human primates, reaching up to 290% of normal levels. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":5514,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[282],"tags":[66,359,432,285,286],"class_list":["post-5512","post","type-post","status-publish","format-standard","has-post-thumbnail","category-editorials","tag-duchenne-muscular-dystrophy","tag-full-length-dystrophin","tag-ripple","tag-sonothera","tag-ultrasound-mediated-delivery"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/5512","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/comments?post=5512"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/5512\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media\/5514"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media?parent=5512"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/categories?post=5512"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/tags?post=5512"}],"curies":[{"name":"\u0648\u0648\u0631\u062f\u0628\u0631\u064a\u0633","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}