{"id":5285,"date":"2025-12-03T17:41:43","date_gmt":"2025-12-03T14:41:43","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=5285"},"modified":"2025-12-03T17:52:01","modified_gmt":"2025-12-03T14:52:01","slug":"capricor-therapeutics-announces-positive-topline-results","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ar\/capricor-therapeutics-announces-positive-topline-results\/","title":{"rendered":"\u0623\u0639\u0644\u0646\u062a \u0634\u0631\u0643\u0629 Capricor Therapeutics \u0639\u0646 \u0646\u062a\u0627\u0626\u062c \u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0645\u0646 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629 \u0645\u0646 \u062f\u0631\u0627\u0633\u0629 HOPE-3 \u0627\u0644\u0645\u062d\u0648\u0631\u064a\u0629 \u0644\u062f\u0648\u0627\u0621 Deramiocel \u0641\u064a \u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u062f\u0648\u0634\u064a\u0646"},"content":{"rendered":"

HOPE-3 \u0647\u064a \u062a\u062c\u0631\u0628\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0639\u0634\u0648\u0627\u0626\u064a\u0629\u060c \u0645\u0632\u062f\u0648\u062c\u0629 \u0627\u0644\u062a\u0639\u0645\u064a\u0629\u060c \u0645\u064f\u062d\u0643\u0645\u0629 \u0628\u062f\u0648\u0627\u0621 \u0648\u0647\u0645\u064a\u060c \u0645\u0646 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629\u060c \u062a\u064f\u0642\u064a\u0651\u0645 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 Deramiocel \u0644\u062f\u0649 \u0627\u0644\u0641\u062a\u064a\u0627\u0646 \u0648\u0627\u0644\u0634\u0628\u0627\u0628 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u062f\u0648\u0634\u064a\u0646. \u0648\u0632\u0651\u0639\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0639\u0634\u0648\u0627\u0626\u064a\u064b\u0627 \u0639\u0644\u0649 106 \u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0645\u0646 20 \u0645\u0631\u0643\u0632\u064b\u0627 \u0633\u0631\u064a\u0631\u064a\u064b\u0627 \u0631\u0627\u0626\u062f\u064b\u0627 \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629. \u062a\u0644\u0642\u0649 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0648\u0646 Deramiocel \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0648\u0631\u064a\u062f \u0628\u062c\u0631\u0639\u0629 150 \u0645\u0644\u064a\u0648\u0646 \u062e\u0644\u064a\u0629 \u0644\u0643\u0644 \u062c\u0631\u0639\u0629\u060c \u0623\u0648 \u062f\u0648\u0627\u0621\u064b \u0648\u0647\u0645\u064a\u064b\u0627 \u0643\u0644 \u062b\u0644\u0627\u062b\u0629 \u0623\u0634\u0647\u0631 \u0644\u0645\u062f\u0629 12 \u0634\u0647\u0631\u064b\u0627.<\/p>\n\n\n\n

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\u0646\u062a\u0627\u0626\u062c \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u062e\u0637 \u0627\u0644\u0639\u0644\u0648\u064a<\/h2>\n\n\n\n
\u0646\u0642\u0637\u0629 \u0627\u0644\u0646\u0647\u0627\u064a\u0629<\/strong><\/td>% \u0625\u0628\u0637\u0627\u0621 \u0627\u0644\u062a\u0642\u062f\u0645<\/strong>3<\/strong><\/sup>
(Deramiocel \u0645\u0642\u0627\u0628\u0644 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0648\u0647\u0645\u064a)<\/strong><\/td>		\u0642\u064a\u0645\u0629 p<\/strong><\/td><\/tr>
\u0623\u062f\u0627\u0621 \u0627\u0644\u0637\u0631\u0641 \u0627\u0644\u0639\u0644\u0648\u064a (PUL v2.0) \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a\u0629<\/strong>\u00b9
(\u0623\u0633\u0627\u0633\u064a\u060c \u0646=105)<\/td>		54%<\/td>\u0635=0.029<\/td><\/tr>
\u0643\u0633\u0631 \u0627\u0644\u0642\u0630\u0641 \u0627\u0644\u0628\u0637\u064a\u0646\u064a \u0627\u0644\u0623\u064a\u0633\u0631 (LVEF %)<\/strong>\u00b2
(\u0627\u0644\u0645\u0641\u062a\u0627\u062d \u0627\u0644\u062b\u0627\u0646\u0648\u064a\u060c \u0639\u062f\u062f = 83)<\/td>		91%<\/td>\u0635=0.041<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u00b9 n \u064a\u0639\u0643\u0633 \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u0636\u0649 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 ITT \u0627\u0644\u0630\u064a\u0646 \u0644\u062f\u064a\u0647\u0645 \u062a\u0642\u064a\u064a\u0645\u0627\u062a PUL v2.0 \u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u062a\u0642\u064a\u064a\u0645 \u0628\u0639\u062f 12 \u0634\u0647\u0631\u064b\u0627.
\u064a\u0639\u0643\u0633 \u00b2 n \u0639\u062f\u062f \u0627\u0644\u0645\u0631\u0636\u0649 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 ITT \u0627\u0644\u0630\u064a\u0646 \u062e\u0636\u0639\u0648\u0627 \u0644\u062a\u0642\u064a\u064a\u0645\u0627\u062a LVEF \u0644\u0644\u0642\u0644\u0628 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u062a\u0635\u0648\u064a\u0631 \u0628\u0627\u0644\u0631\u0646\u064a\u0646 \u0627\u0644\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a \u0648\u0627\u0644\u062a\u064a \u062a\u0645\u062a \u0645\u0631\u0627\u062c\u0639\u062a\u0647\u0627 \u0648\u062a\u0642\u064a\u064a\u0645\u0647\u0627 \u0645\u0631\u0643\u0632\u064a\u064b\u0627 \u0641\u064a 12 \u0634\u0647\u0631\u064b\u0627.
3 <\/sup>\u064a\u062a\u0645 \u062d\u0633\u0627\u0628 \u0646\u0633\u0628\u0629 \u0627\u0644\u062a\u0628\u0627\u0637\u0624 \u0639\u0644\u0649 \u0623\u0646\u0647\u0627 \u0641\u0631\u0642 \u0627\u0644\u0639\u0644\u0627\u062c \u0645\u0642\u0633\u0648\u0645\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u062a\u063a\u064a\u0631 \u0641\u064a \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0648\u0647\u0645\u064a \u0639\u0646 \u062e\u0637 \u0627\u0644\u0623\u0633\u0627\u0633.<\/p>\n\n\n\n

\u062a\u0627\u0628\u0639 \u0647\u0630\u0647 \u0627\u0644\u0635\u0641\u062d\u0629<\/strong> >>> \u062c\u0645\u064a\u0639 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646<\/a><\/p>","protected":false},"excerpt":{"rendered":"

HOPE-3 is a randomized, double-blind, placebo-controlled, Phase 3 clinical trial evaluating Deramiocel in boys and young men with Duchenne muscular dystrophy. The study randomized 106 participants across 20 leading U.S. clinical sites. Participants received intravenous Deramiocel at 150 million cells per infusion or placebo every three months for a 12-month period. The average age of […]<\/p>\n","protected":false},"author":1,"featured_media":5287,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[281],"tags":[86,87,303,137,85],"class_list":["post-5285","post","type-post","status-publish","format-standard","has-post-thumbnail","category-press-releases","tag-capricor","tag-capricor-therapeutics","tag-cell-therapy","tag-clinical-trial","tag-deramiocel"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/5285","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/comments?post=5285"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/5285\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media\/5287"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media?parent=5285"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/categories?post=5285"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/tags?post=5285"}],"curies":[{"name":"\u0648\u0648\u0631\u062f\u0628\u0631\u064a\u0633","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}