{"id":4559,"date":"2025-09-25T12:50:25","date_gmt":"2025-09-25T09:50:25","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=4559"},"modified":"2025-11-03T20:20:40","modified_gmt":"2025-11-03T17:20:40","slug":"mutations-and-deletions-amenable-to-exon-53-skipping-therapies-dmd","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ar\/mutations-and-deletions-amenable-to-exon-53-skipping-therapies-dmd\/","title":{"rendered":"\u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0648\u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0642\u0627\u0628\u0644 \u0644\u0644\u0639\u0644\u0627\u062c \u0628\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0644\u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u062f\u0648\u0634\u064a\u0646"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a (DMD) \u0647\u0648 \u0627\u0636\u0637\u0631\u0627\u0628 \u0648\u0631\u0627\u062b\u064a \u0645\u064f\u0646\u0647\u0643 \u0648\u0645\u062a\u0641\u0627\u0642\u0645\u060c \u064a\u0635\u064a\u0628 \u0627\u0644\u0623\u0648\u0644\u0627\u062f \u0628\u0634\u0643\u0644 \u0631\u0626\u064a\u0633\u064a\u060c \u0645\u0633\u0628\u0628\u064b\u0627 \u0636\u0639\u0641\u064b\u0627 \u0639\u0636\u0644\u064a\u064b\u0627 \u0648\u062a\u0646\u0643\u0633\u064b\u0627 \u0628\u0633\u0628\u0628 \u0637\u0641\u0631\u0627\u062a \u0641\u064a \u062c\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646. \u0639\u0644\u0649 \u0645\u0631 \u0627\u0644\u0633\u0646\u064a\u0646\u060c \u0637\u0631\u0623\u062a \u062a\u0637\u0648\u0631\u0627\u062a \u0639\u0644\u0627\u062c\u064a\u0629 \u0644\u0648\u0642\u0641 \u062a\u0637\u0648\u0631 \u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a\u060c \u0648\u0645\u0646 \u0623\u0628\u0631\u0632\u0647\u0627 \u0639\u0644\u0627\u062c\u0627\u062a \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a. \u062a\u0647\u062f\u0641 \u0647\u0630\u0647 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0625\u0644\u0649 \u062a\u062c\u0627\u0648\u0632 \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0627\u0644\u0645\u0639\u064a\u0628\u0629 \u0641\u064a \u062c\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646\u060c \u0645\u0645\u0627 \u064a\u0633\u0645\u062d \u0628\u0625\u0646\u062a\u0627\u062c \u0628\u0631\u0648\u062a\u064a\u0646 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0648\u0638\u064a\u0641\u064a\u060c \u062d\u062a\u0649 \u0645\u0639 \u0648\u062c\u0648\u062f \u0637\u0641\u0631\u0627\u062a \u062c\u064a\u0646\u064a\u0629. \u064a\u064f\u0639\u062f \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0623\u062d\u062f \u0647\u0630\u0647 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u0648\u062c\u0647\u0629 \u0627\u0644\u062a\u064a \u062d\u0638\u064a\u062a \u0628\u0627\u0647\u062a\u0645\u0627\u0645 \u0643\u0628\u064a\u0631 \u0641\u064a \u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a. <strong>\u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u0645\u0642\u0627\u0644\u0629\u060c \u0633\u0648\u0641 \u0646\u0633\u062a\u0643\u0634\u0641 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0648\u0627\u0644\u062d\u0630\u0641 \u0641\u064a \u062c\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0627\u0644\u0630\u064a \u064a\u0645\u0643\u0646 \u0639\u0644\u0627\u062c\u0647 \u0639\u0646 \u0637\u0631\u064a\u0642 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0648\u0643\u064a\u0641 \u064a\u0642\u062f\u0645 \u0647\u0630\u0627 \u0627\u0644\u0646\u0647\u062c \u0627\u0644\u0623\u0645\u0644 \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646.<\/strong> - \u064a\u062a\u0639\u0644\u0645 \u0623\u0643\u062b\u0631: <a href=\"https:\/\/dmdwarrior.com\/ar\/what-is-duchenne\/\" target=\"_blank\" data-type=\"post\" data-id=\"588\" rel=\"noreferrer noopener\">\u0645\u0627 \u0647\u0648 \u062f\u0648\u0634\u064a\u0646\u061f<\/a> \u2013<\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>\u062c\u062f\u0648\u0644 \u0627\u0644\u0645\u062d\u062a\u0648\u064a\u0627\u062a<\/h2><nav><ul><li><a href=\"#exon-skipping-a-breakthrough-approach-for-dmd\">\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646: \u0646\u0647\u062c \u0645\u0628\u062a\u0643\u0631 \u0644\u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0634\u064a\u0646\u064a<\/a><\/li><li><a href=\"#how-exon-53-skipping-works-for-dmd\">\u0643\u064a\u0641 \u064a\u0639\u0645\u0644 \u062a\u062e\u0637\u064a \u0625\u0643\u0633\u0648\u0646 53 \u0644\u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0634\u064a\u0646\u064a<\/a><\/li><li><a href=\"#mutations-and-deletions-amenable-to-exon-53-skipping\">\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u062a\u062e\u0637\u064a \u0641\u064a Exon 53<\/a><\/li><li><a href=\"#common-deletions-amenable-to-exon-53-skipping\">\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0634\u0627\u0626\u0639\u0629 \u0627\u0644\u062a\u064a \u064a\u0645\u0643\u0646 \u062a\u062e\u0637\u064a\u0647\u0627 \u0641\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53<\/a><\/li><li><a href=\"#mutations-amenable-to-exon-51-skipping\">\u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u0642\u0627\u0628\u0644\u0629 \u0644\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53<\/a><ul><li><a href=\"#golodirsen-a-leading-exon-53-skipping-drug\">Golodirsen: \u0639\u0644\u0627\u062c \u0631\u0627\u0626\u062f \u0644\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53<\/a><ul><li><a href=\"#clinical-trials-and-results\">\u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0627\u0644\u0646\u062a\u0627\u0626\u062c<\/a><\/li><\/ul><\/li><li><a href=\"#benefits-of-exon-53-skipping-therapy-for-dmd-patients\">\u0641\u0648\u0627\u0626\u062f \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u062a\u062e\u0637\u064a \u0625\u0643\u0633\u0648\u0646 53 \u0644\u0645\u0631\u0636\u0649 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a<\/a><\/li><li><a href=\"#future-prospects-expanding-exon-skipping-therapies\">\u0627\u0644\u0622\u0641\u0627\u0642 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u064a\u0629: \u062a\u0648\u0633\u064a\u0639 \u0646\u0637\u0627\u0642 \u0639\u0644\u0627\u062c\u0627\u062a \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646<\/a><\/li><\/ul><\/li><li><a href=\"#summary-is-your-child-a-candidate-for-exon-51-skipping\">\u0645\u0644\u062e\u0635: \u0647\u0644 \u0627\u0628\u0646\u064a \u0645\u0631\u0634\u062d \u0644\u062a\u062e\u0637\u064a Exon 53\u061f<\/a><ul><li><a href=\"#conclusion\">\u062e\u0627\u062a\u0645\u0629<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"exon-skipping-a-breakthrough-approach-for-dmd\"><strong>\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646: \u0646\u0647\u062c \u0645\u0628\u062a\u0643\u0631 \u0644\u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0634\u064a\u0646\u064a<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0647\u0648 \u0634\u0643\u0644 \u0645\u0646 \u0623\u0634\u0643\u0627\u0644 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u064a\u0647\u062f\u0641 \u0625\u0644\u0649 &quot;\u062a\u062e\u0637\u064a&quot; \u0627\u0644\u0623\u062c\u0632\u0627\u0621 \u0627\u0644\u0645\u0639\u064a\u0628\u0629 (\u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a) \u0645\u0646 \u062c\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0623\u062b\u0646\u0627\u0621 \u0639\u0645\u0644\u064a\u0629 \u0631\u0628\u0637 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0631\u064a\u0628\u0648\u0632\u064a. \u0627\u0644\u0647\u062f\u0641 \u0647\u0648 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0625\u0637\u0627\u0631 \u0627\u0644\u0642\u0631\u0627\u0621\u0629 \u0644\u0644\u062c\u064a\u0646 \u0648\u062a\u0645\u0643\u064a\u0646 \u0625\u0646\u062a\u0627\u062c \u0646\u0633\u062e\u0629 \u0645\u062e\u062a\u0635\u0631\u0629 \u0648\u0644\u0643\u0646\u0647\u0627 \u0641\u0639\u0627\u0644\u0629 \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646. \u064a\u064f\u0639\u062f \u0647\u0630\u0627 \u0627\u0644\u0646\u0647\u062c \u0645\u0641\u064a\u062f\u064b\u0627 \u0628\u0634\u0643\u0644 \u062e\u0627\u0635 \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u062d\u0630\u0641 \u0645\u062d\u062f\u062f \u0641\u064a \u062c\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u062e\u0644\u0644 \u0641\u064a \u0625\u0637\u0627\u0631 \u0627\u0644\u0642\u0631\u0627\u0621\u0629\u060c \u0648\u0627\u0644\u0630\u064a \u0639\u0627\u062f\u0629\u064b \u0645\u0627 \u064a\u0646\u062a\u062c \u0628\u0631\u0648\u062a\u064a\u0646 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u063a\u064a\u0631 \u0641\u0639\u0627\u0644. - \u0627\u0642\u0631\u0623 \u0627\u0644\u0645\u0632\u064a\u062f: <a href=\"https:\/\/dmdwarrior.com\/ar\/what-is-exon-skipping-and-how-does-it-work\/\" target=\"_blank\" data-type=\"post\" data-id=\"1445\" rel=\"noreferrer noopener\">\u0645\u0627 \u0647\u0648 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u061f<\/a> \u2013<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0628\u062a\u062e\u0637\u064a \u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0645\u0639\u064a\u0646\u0629\u060c \u0645\u062b\u0644 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 \u0665\u0663\u060c \u064a\u064f\u0639\u064a\u062f \u0627\u0644\u0639\u0644\u0627\u062c \u0636\u0628\u0637 \u0625\u0637\u0627\u0631 \u0627\u0644\u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u0635\u062d\u064a\u062d\u060c \u0645\u0645\u0627 \u064a\u0633\u0645\u062d \u0628\u0625\u0646\u062a\u0627\u062c \u0628\u0631\u0648\u062a\u064a\u0646 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0648\u0638\u064a\u0641\u064a \u064a\u064f\u0633\u0627\u0639\u062f \u0641\u064a \u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0648\u0648\u0638\u0627\u0626\u0641\u0647\u0627. \u0644\u0627 \u064a\u064f\u0639\u0627\u0644\u062c \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a\u060c \u0648\u0644\u0643\u0646\u0647 \u064a\u064f\u0628\u0637\u0626 \u062a\u0637\u0648\u0631 \u0627\u0644\u0645\u0631\u0636 \u0648\u064a\u064f\u062d\u0633\u0651\u0646 \u062c\u0648\u062f\u0629 \u062d\u064a\u0627\u0629 \u0627\u0644\u0645\u0631\u0636\u0649.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"how-exon-53-skipping-works-for-dmd\"><strong>\u0643\u064a\u0641 \u064a\u0639\u0645\u0644 \u062a\u062e\u0637\u064a \u0625\u0643\u0633\u0648\u0646 53 \u0644\u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0634\u064a\u0646\u064a<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u064a\u0633\u062a\u0647\u062f\u0641 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0628\u0634\u0643\u0644 \u062e\u0627\u0635 \u0645\u0646\u0637\u0642\u0629 \u0645\u0646 \u062c\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0627\u0644\u062a\u064a \u062a\u0639\u062f \u0645\u0647\u0645\u0629 \u0644\u0625\u0646\u062a\u0627\u062c \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646. <strong>\u0644\u0642\u062f \u0623\u0635\u0628\u062d \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0646\u0647\u062c\u064b\u0627 \u0639\u0644\u0627\u062c\u064a\u064b\u0627 \u0631\u0626\u064a\u0633\u064a\u064b\u0627 \u0644\u0623\u0646\u0647 \u064a\u0639\u0627\u0644\u062c \u0645\u062c\u0645\u0648\u0639\u0629 \u0641\u0631\u0639\u064a\u0629 \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0639\u0645\u0644\u064a\u0627\u062a \u062d\u0630\u0641 \u062a\u062a\u0639\u0644\u0642 \u0628\u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0623\u0648 \u0627\u0644\u0645\u0646\u0627\u0637\u0642 \u0627\u0644\u0645\u062d\u064a\u0637\u0629 \u0628\u0627\u0644\u062c\u064a\u0646.<\/strong> \u062a\u0624\u062f\u064a \u0647\u0630\u0647 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0625\u0644\u0649 \u062a\u0639\u0637\u064a\u0644 \u0625\u0637\u0627\u0631 \u0627\u0644\u0642\u0631\u0627\u0621\u0629\u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u062e\u0644\u0644 \u0641\u064a \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0623\u0648 \u063a\u064a\u0627\u0628\u0647.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0639\u0646\u062f \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0623\u062b\u0646\u0627\u0621 \u0639\u0645\u0644\u064a\u0629 \u0631\u0628\u0637 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0631\u064a\u0628\u0648\u0632\u064a\u060c \u064a\u064f\u0633\u062a\u0639\u0627\u062f \u0625\u0637\u0627\u0631 \u0627\u0644\u0642\u0631\u0627\u0621\u0629\u060c \u0648\u064a\u0645\u0643\u0646 \u0625\u0646\u062a\u0627\u062c \u0628\u0631\u0648\u062a\u064a\u0646 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0645\u064f\u062e\u062a\u0635\u0631 \u0648\u0644\u0643\u0646\u0647 \u0641\u0639\u0627\u0644. \u0647\u0630\u0627 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0627\u0644\u0645\u064f\u062e\u062a\u0635\u0631 \u0644\u064a\u0633 \u0628\u062d\u062c\u0645 \u0623\u0648 \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0643\u0627\u0645\u0644 \u0627\u0644\u0637\u0648\u0644\u060c \u0648\u0644\u0643\u0646\u0647 \u0644\u0627 \u064a\u0632\u0627\u0644 \u064a\u0648\u0641\u0631 \u062b\u0628\u0627\u062a\u064b\u0627 \u0643\u0627\u0641\u064a\u064b\u0627 \u0644\u062d\u0645\u0627\u064a\u0629 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0645\u0646 \u0627\u0644\u062a\u0644\u0641. \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u064f\u0628\u0637\u0626 \u0647\u0630\u0627 \u0627\u0644\u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0644\u0625\u0646\u062a\u0627\u062c \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u062a\u0637\u0648\u0631 \u0627\u0644\u0645\u0631\u0636\u060c \u0648\u064a\u064f\u062d\u0633\u0651\u0646 \u0642\u0648\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a\u060c \u0648\u064a\u064f\u0624\u062e\u0631 \u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u062d\u0631\u0643\u064a\u0629.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"mutations-and-deletions-amenable-to-exon-53-skipping\"><strong>\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u062a\u062e\u0637\u064a \u0641\u064a Exon 53<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u064a\u0645\u062b\u0644 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u0639\u0644\u0627\u062c\u064a\u0629 \u0645\u0633\u062a\u0647\u062f\u0641\u0629 \u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0641\u0631\u0639\u064a\u0629 \u0645\u0646 \u0645\u0631\u0636\u0649 \u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a\u060c \u0648\u062e\u0627\u0635\u0629 \u0623\u0648\u0644\u0626\u0643 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0630\u064a \u064a\u062a\u0636\u0645\u0646 \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a<\/strong>: 3-52, 4-52, 5-52, 6-52, 9-52, 10-52, 11-52, 13-52, 14-52, 15-52, 16-52, 17-52, 19-52, 21-52, 23-52, 24-52, 25-52, 26-52 27-52, 28-52, 29-52, 30-52, 31-52, 32-52, 33-52, 34-52, 35-52, 36-52, 37-52, 38-52, 39-52, 40-52, 41-52, 42-52, 43-52, 45-52, 47-52, 48-52, 49-52, 50-52, 52, 54-58, 54-61, 54-63, 54-64, 54-66, 54-76, 54-77.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"847\" height=\"1024\" src=\"https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-847x1024.jpg\" alt=\"\u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0648\u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0642\u0627\u0628\u0644 \u0644\u0644\u0639\u0644\u0627\u062c \u0628\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0644\u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u062f\u0648\u0634\u064a\u0646\" class=\"wp-image-4566\" title=\"\" srcset=\"https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-847x1024.jpg 847w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-248x300.jpg 248w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-768x929.jpg 768w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-1270x1536.jpg 1270w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-1693x2048.jpg 1693w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-10x12.jpg 10w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-347x420.jpg 347w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-150x181.jpg 150w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-300x363.jpg 300w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-696x842.jpg 696w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-1068x1292.jpg 1068w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping-1920x2323.jpg 1920w, https:\/\/dmdwarrior.com\/wp-content\/uploads\/2025\/09\/amenable-to-exon-53-skipping.jpg 1984w\" sizes=\"auto, (max-width: 847px) 100vw, 847px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u0644\u0643\u064a \u064a\u0643\u0648\u0646 \u0627\u0644\u0645\u0631\u064a\u0636 \u0645\u0631\u0634\u062d\u064b\u0627 \u0644\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53\u060c \u064a\u062c\u0628 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0644\u062f\u064a\u0647 \u062d\u0630\u0641 \u0625\u0637\u0627\u0631\u064a \u064a\u0645\u0643\u0646 \u062a\u0635\u062d\u064a\u062d\u0647 \u0639\u0646 \u0637\u0631\u064a\u0642 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53. \u0648\u0627\u0644\u0647\u062f\u0641 \u0647\u0648 \u0625\u0639\u0627\u062f\u0629 \u062c\u064a\u0646 DMD \u0625\u0644\u0649 \u0625\u0637\u0627\u0631 \u0627\u0644\u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u0635\u062d\u064a\u062d.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"common-deletions-amenable-to-exon-53-skipping\"><strong>\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0634\u0627\u0626\u0639\u0629 \u0627\u0644\u062a\u064a \u064a\u0645\u0643\u0646 \u062a\u062e\u0637\u064a\u0647\u0627 \u0641\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u064a\u064f\u0639\u062f\u0651 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0641\u0639\u0627\u0644\u0627\u064b \u0644\u0645\u0631\u0636\u0649 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u062d\u0630\u0641 \u062c\u064a\u0646\u0627\u062a \u0645\u062d\u062f\u062f\u0629 \u062a\u064f\u0639\u0637\u0651\u0644 \u0625\u0637\u0627\u0631 \u0642\u0631\u0627\u0621\u0629 \u062c\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646. \u062a\u0634\u0645\u0644 \u0623\u0643\u062b\u0631 \u062d\u0627\u0644\u0627\u062a \u0627\u0644\u062d\u0630\u0641 \u0634\u064a\u0648\u0639\u064b\u0627 \u0627\u0644\u062a\u064a \u064a\u064f\u0645\u0643\u0646 \u0639\u0644\u0627\u062c\u0647\u0627 \u0628\u0647\u0630\u0627 \u0627\u0644\u0639\u0644\u0627\u062c \u0645\u0627 \u064a\u0644\u064a:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u062d\u0630\u0641 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 52<\/strong>\u064a\u0624\u062f\u064a \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0645\u0628\u0627\u0634\u0631 \u0644\u0644\u0625\u0643\u0633\u0648\u0646 52 \u0625\u0644\u0649 \u0637\u0641\u0631\u0629 \u0625\u0637\u0627\u0631\u064a\u0629\u060c \u062a\u064f\u0646\u062a\u062c \u0628\u0631\u0648\u062a\u064a\u0646 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u063a\u064a\u0631 \u0648\u0638\u064a\u0641\u064a. \u064a\u0624\u062f\u064a \u062a\u062e\u0637\u064a \u0647\u0630\u0627 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 \u0625\u0644\u0649 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0625\u0637\u0627\u0631 \u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u062c\u064a\u0646\u060c \u0645\u0645\u0627 \u064a\u0633\u0645\u062d \u0628\u0625\u0646\u062a\u0627\u062c \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0648\u0638\u064a\u0641\u064a.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u062a\u064a \u062a\u0645\u062a\u062f \u0639\u0628\u0631 \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0645\u0646 45 \u0625\u0644\u0649 52<\/strong>:\u064a\u0645\u0643\u0646 \u0623\u064a\u0636\u064b\u0627 \u062a\u0635\u062d\u064a\u062d \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0630\u064a \u064a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0645\u0646 45 \u0625\u0644\u0649 52 \u0639\u0646 \u0637\u0631\u064a\u0642 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53\u060c \u0648\u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646\u060c \u0648\u062a\u062b\u0628\u064a\u062a \u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0627\u0644\u062d\u0630\u0641 \u0628\u064a\u0646 \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a 50 \u0625\u0644\u0649 52<\/strong>:\u064a\u0624\u062f\u064a \u0647\u0630\u0627 \u0627\u0644\u0646\u0648\u0639 \u0645\u0646 \u0627\u0644\u062d\u0630\u0641 \u0625\u0644\u0649 \u062a\u062d\u0648\u0644 \u0625\u0637\u0627\u0631\u064a \u064a\u0645\u0643\u0646 \u0625\u0635\u0644\u0627\u062d\u0647 \u0639\u0646 \u0637\u0631\u064a\u0642 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53\u060c \u0645\u0645\u0627 \u064a\u0633\u0645\u062d \u0628\u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0639\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0645\u0642\u0637\u0648\u0639 \u0648\u0644\u0643\u0646\u0647 \u0648\u0638\u064a\u0641\u064a.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"mutations-amenable-to-exon-51-skipping\"><strong>\u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u0642\u0627\u0628\u0644\u0629 \u0644\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u062a\u062a\u0636\u0645\u0646 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u0642\u0627\u0628\u0644\u0629 \u0644\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0641\u064a \u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0627\u0644\u062a\u0627\u0644\u064a\u0629<\/strong>: 3-52, 4-52, 5-52, 6-52, 9-52, 10-52, 11-52, 13-52, 14-52, 15-52, 16-52, 17-52, 19-52, 21-52, 23-52, 24-52, 25-52, 26-52 27-52, 28-52, 29-52, 30-52, 31-52, 32-52, 33-52, 34-52, 35-52, 36-52, 37-52, 38-52, 39-52, 40-52, 41-52, 42-52, 43-52, 45-52, 47-52, 48-52, 49-52, 50-52, 52, 54-58, 54-61, 54-63, 54-64, 54-66, 54-76, 54-77.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"golodirsen-a-leading-exon-53-skipping-drug\"><strong>Golodirsen: \u0639\u0644\u0627\u062c \u0631\u0627\u0626\u062f \u0644\u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Golodirsen (Vyondys 53) \u0647\u0648 \u0623\u0648\u0644\u064a\u062c\u0648\u0646\u0648\u0643\u0644\u064a\u0648\u062a\u064a\u062f \u0645\u0636\u0627\u062f \u0644\u0644\u0627\u062a\u062c\u0627\u0647 \u0645\u0639\u062a\u0645\u062f \u0645\u0646 FDA (AON) \u064a\u0639\u0645\u0644 \u0639\u0644\u0649 \u062a\u0639\u0632\u064a\u0632 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53.<\/strong> \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0628\u0646\u0633\u062e\u0629 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0631\u064a\u0628\u0648\u0632\u064a \u0644\u062c\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646\u060c \u064a\u064f\u062c\u0628\u0631 \u0628\u0631\u0648\u062a\u064a\u0646 \u063a\u0648\u0644\u0648\u062f\u064a\u0631\u0633\u0646 \u0622\u0644\u064a\u0629 \u0627\u0644\u0631\u0628\u0637 \u0639\u0644\u0649 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0623\u062b\u0646\u0627\u0621 \u0645\u0639\u0627\u0644\u062c\u0629 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0631\u064a\u0628\u0648\u0632\u064a\u060c \u0645\u0645\u0627 \u064a\u064f\u0639\u064a\u062f \u0625\u0637\u0627\u0631 \u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u062c\u064a\u0646 \u0628\u0641\u0639\u0627\u0644\u064a\u0629. \u064a\u064f\u0645\u0643\u0651\u0646 \u0647\u0630\u0627 \u0645\u0646 \u0625\u0646\u062a\u0627\u062c \u0628\u0631\u0648\u062a\u064a\u0646 \u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0648\u0638\u064a\u0641\u064a \u0648\u0644\u0643\u0646\u0647 \u0645\u064f\u062e\u062a\u0635\u0631. <strong>(\u0642\u062f \u064a\u062a\u0645 \u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u0644\u062f\u064a\u0647\u0645 \u062d\u0630\u0641 \u0641\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 52 \u0628\u0639\u0644\u0627\u062c \u064a\u062a\u062e\u0637\u0649 \u0625\u0645\u0627 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 51 \u0623\u0648 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53.)<\/strong> \u2013 <a href=\"https:\/\/www.vyondys53.com\/\" data-type=\"link\" data-id=\"https:\/\/www.vyondys53.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0627\u0642\u0631\u0623 \u0627\u0644\u0645\u0632\u064a\u062f<\/a> \u2013 <\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"clinical-trials-and-results\"><strong>\u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0627\u0644\u0646\u062a\u0627\u0626\u062c<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u0641\u064a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629\u060c \u0623\u0638\u0647\u0631 \u062f\u0648\u0627\u0621 \u062c\u0648\u0644\u0648\u062f\u064a\u0631\u0633\u0646 \u0632\u064a\u0627\u062f\u0629 \u0645\u0644\u062d\u0648\u0638\u0629 \u0641\u064a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0641\u064a \u062e\u0632\u0639\u0627\u062a \u0627\u0644\u0639\u0636\u0644\u0627\u062a\u060c \u0648\u0647\u0648 \u0645\u0624\u0634\u0631 \u062d\u0627\u0633\u0645 \u0639\u0644\u0649 \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0639\u0644\u0627\u062c. \u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646 \u0643\u0645\u064a\u0629 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0627\u0644\u0645\u064f\u0646\u062a\u062c\u0629 \u0623\u0642\u0644 \u0645\u0646 \u0627\u0644\u0643\u0645\u064a\u0629 \u0627\u0644\u0643\u0627\u0645\u0644\u0629 \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a \u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0633\u0644\u064a\u0645\u0629\u060c \u0625\u0644\u0627 \u0623\u0646\u0647\u0627 \u0643\u0627\u0641\u064a\u0629 \u0644\u062d\u0645\u0627\u064a\u0629 \u0623\u0644\u064a\u0627\u0641 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0645\u0646 \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u062a\u0644\u0641 \u0648\u0625\u0628\u0637\u0627\u0621 \u062a\u0637\u0648\u0631 \u0627\u0644\u0645\u0631\u0636.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0641\u0639\u0627\u0644\u064a\u0629:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0623\u0638\u0647\u0631\u062a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0623\u0646 \u0639\u0642\u0627\u0631 \u062c\u0648\u0644\u0648\u062f\u064a\u0631\u0633\u064a\u0646 \u0646\u062c\u062d \u0641\u064a \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0639\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u062d\u0630\u0641 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53.<\/li>\n\n\n\n<li>\u0648\u0641\u064a \u062d\u064a\u0646 \u0638\u0644\u062a \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0623\u0642\u0644 \u0645\u0646 \u062a\u0644\u0643 \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0639\u0636\u0644\u064a\u0629 \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629\u060c \u0643\u0627\u0646\u062a \u0627\u0644\u0643\u0645\u064a\u0629 \u0627\u0644\u0645\u0646\u062a\u062c\u0629 \u0643\u0627\u0641\u064a\u0629 \u0644\u062a\u0648\u0641\u064a\u0631 \u0628\u062f\u064a\u0644 \u0648\u0638\u064a\u0641\u064a\u060c \u0645\u0645\u0627 \u064a\u0642\u0644\u0644 \u0645\u0646 \u0634\u062f\u0629 \u0636\u0639\u0641 \u0627\u0644\u0639\u0636\u0644\u0627\u062a.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0645\u0644\u0641 \u0627\u0644\u0633\u0644\u0627\u0645\u0629:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0643\u0627\u0646 \u0633\u062c\u0644 \u0633\u0644\u0627\u0645\u0629 \u062f\u0648\u0627\u0621 \u063a\u0648\u0644\u0648\u062f\u064a\u0631\u0633\u0646 \u0625\u064a\u062c\u0627\u0628\u064a\u064b\u0627\u060c \u0645\u0639 \u0622\u062b\u0627\u0631 \u062c\u0627\u0646\u0628\u064a\u0629 \u062e\u0641\u064a\u0641\u0629 \u0625\u0644\u0649 \u0645\u062a\u0648\u0633\u0637\u0629\u060c \u062a\u0634\u0645\u0644 \u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0645\u0648\u0636\u0639 \u0627\u0644\u062d\u0642\u0646 \u0648\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u062a\u0646\u0641\u0633\u064a. \u0648\u0647\u0630\u0647 \u0627\u0644\u0622\u062b\u0627\u0631 \u0634\u0627\u0626\u0639\u0629 \u0641\u064a \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u064f\u0639\u0637\u0649 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u062a\u0633\u0631\u064a\u0628 \u0627\u0644\u0648\u0631\u064a\u062f\u064a.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"benefits-of-exon-53-skipping-therapy-for-dmd-patients\"><strong>\u0641\u0648\u0627\u0626\u062f \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u062a\u062e\u0637\u064a \u0625\u0643\u0633\u0648\u0646 53 \u0644\u0645\u0631\u0636\u0649 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u062a\u0648\u0641\u0631 \u0639\u0644\u0627\u062c\u0627\u062a \u062a\u062e\u0637\u064a \u0625\u0643\u0633\u0648\u0646 53 \u0645\u062b\u0644 golodirsen \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0641\u0648\u0627\u0626\u062f \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u062f\u0648\u0634\u064a\u0646:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u064a\u0628\u0637\u0626 \u062a\u0642\u062f\u0645 \u0627\u0644\u0645\u0631\u0636:<\/strong> \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0625\u0646\u062a\u0627\u062c \u0628\u0639\u0636 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646\u060c \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0624\u062f\u064a \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 \u0625\u0644\u0649 \u0625\u0628\u0637\u0627\u0621 \u0627\u0646\u062d\u0644\u0627\u0644 \u0623\u0644\u064a\u0627\u0641 \u0627\u0644\u0639\u0636\u0644\u0627\u062a\u060c \u0645\u0645\u0627 \u064a\u0633\u0627\u0639\u062f \u0641\u064a \u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0642\u0648\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0648\u0648\u0638\u064a\u0641\u062a\u0647\u0627.<\/li>\n\n\n\n<li><strong>\u062a\u062d\u0633\u064a\u0646 \u0646\u0648\u0639\u064a\u0629 \u0627\u0644\u062d\u064a\u0627\u0629:<\/strong> \u0645\u0639 \u062a\u062d\u0633\u0646 \u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u0639\u0636\u0644\u0627\u062a\u060c \u0642\u062f \u064a\u0639\u0627\u0646\u064a \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0645\u0646 \u062a\u0639\u0628 \u0623\u0642\u0644 \u0648\u0642\u062f\u0631\u0629 \u0623\u0643\u0628\u0631 \u0639\u0644\u0649 \u0627\u0644\u062d\u0631\u0643\u0629\u060c \u0645\u0645\u0627 \u064a\u0633\u0645\u062d \u0644\u0647\u0645 \u0628\u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0627\u0644\u0627\u0633\u062a\u0642\u0644\u0627\u0644 \u0644\u0641\u062a\u0631\u0627\u062a \u0623\u0637\u0648\u0644.<\/li>\n\n\n\n<li><strong>\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0633\u062a\u0647\u062f\u0641 \u0644\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u0645\u062d\u062f\u062f\u0629:<\/strong> \u064a\u0639\u062f \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u062e\u0627\u0635\u064b\u0627 \u0644\u0644\u063a\u0627\u064a\u0629 \u0628\u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0645\u062d\u064a\u0637 \u0628\u0645\u0646\u0627\u0637\u0642 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 52\u060c \u0645\u0645\u0627 \u064a\u0648\u0641\u0631 \u0646\u0647\u062c\u064b\u0627 \u0639\u0644\u0627\u062c\u064a\u064b\u0627 \u0645\u0635\u0645\u0645\u064b\u0627 \u062e\u0635\u064a\u0635\u064b\u0627 \u0644\u0647\u0630\u0647 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 \u0645\u0631\u0636\u0649 \u062f\u0648\u0634\u064a\u0646.<\/li>\n<\/ol>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"future-prospects-expanding-exon-skipping-therapies\"><strong>\u0627\u0644\u0622\u0641\u0627\u0642 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u064a\u0629: \u062a\u0648\u0633\u064a\u0639 \u0646\u0637\u0627\u0642 \u0639\u0644\u0627\u062c\u0627\u062a \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u0641\u064a \u062d\u064a\u0646 \u064a\u064f\u0645\u062b\u0644 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0625\u0646\u062c\u0627\u0632\u064b\u0627 \u0647\u0627\u0645\u064b\u0627 \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0637\u0641\u0631\u0627\u062a \u0645\u062d\u062f\u062f\u0629\u060c \u0641\u0625\u0646 \u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 \u062a\u0645\u062a\u062f \u0625\u0644\u0649 \u0645\u0627 \u0647\u0648 \u0623\u0628\u0639\u062f \u0645\u0646 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53. \u0648\u064a\u0639\u0645\u0644 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0639\u0644\u0649 \u0639\u0644\u0627\u062c\u0627\u062a \u062a\u0633\u062a\u0647\u062f\u0641 \u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0623\u062e\u0631\u0649 \u0641\u064a \u062c\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a 51 \u064845 \u064844. \u0648\u0645\u0639 \u062a\u0642\u062f\u0645 \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629\u060c \u0633\u062a\u0638\u0647\u0631 \u0639\u0644\u0627\u062c\u0627\u062a \u0623\u0643\u062b\u0631 \u062a\u062e\u0635\u064a\u0635\u064b\u0627\u060c \u0645\u0645\u0627 \u064a\u0645\u0646\u062d \u0627\u0644\u0623\u0645\u0644 \u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0623\u0648\u0633\u0639 \u0645\u0646 \u0645\u0631\u0636\u0649 \u062f\u0648\u0634\u064a\u0646.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0642\u062f \u062a\u064f\u0639\u0632\u0632 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u064f\u0631\u0643\u0651\u0628\u0629\u060c \u0645\u062b\u0644 \u062f\u0645\u062c \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0645\u0639 \u062a\u0642\u0646\u064a\u0627\u062a \u062a\u0639\u062f\u064a\u0644 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0645\u062b\u0644 \u0643\u0631\u064a\u0633\u0628\u0631\u060c \u0641\u0639\u0627\u0644\u064a\u0629 \u0647\u0630\u0647 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a. \u0648\u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0646\u0627\u0647\u062c \u0645\u062a\u0639\u062f\u062f\u0629 \u0628\u0627\u0644\u062a\u0632\u0627\u0645\u0646\u060c \u064a\u0623\u0645\u0644 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0641\u064a \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0628\u0634\u0643\u0644 \u0643\u0627\u0645\u0644 \u0623\u0648 \u0634\u0628\u0647 \u0643\u0627\u0645\u0644\u060c \u0648\u062a\u0648\u0641\u064a\u0631 \u0641\u0648\u0627\u0626\u062f \u0623\u0637\u0648\u0644 \u0623\u0645\u062f\u064b\u0627 \u0644\u0644\u0645\u0631\u0636\u0649. - \u0627\u0642\u0631\u0623 \u0627\u0644\u0645\u0632\u064a\u062f: <a href=\"https:\/\/dmdwarrior.com\/ar\/crispr-cas13-could-accelerate-studies-on-rna-targeted-therapies\/\" target=\"_blank\" data-type=\"post\" data-id=\"1418\" rel=\"noreferrer noopener\">\u0643\u0631\u064a\u0633\u0628\u0631<\/a> \u2013<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"summary-is-your-child-a-candidate-for-exon-51-skipping\"><strong>\u0645\u0644\u062e\u0635: \u0647\u0644 \u0627\u0628\u0646\u064a \u0645\u0631\u0634\u062d \u0644\u062a\u062e\u0637\u064a Exon 53\u061f<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u0625\u0630\u0627 \u062a\u0645 \u062a\u0634\u062e\u064a\u0635 \u0637\u0641\u0644\u0643 \u0628\u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646 \u0648\u0644\u062f\u064a\u0647 \u0637\u0641\u0631\u0629 \u0628\u0627\u0644\u0642\u0631\u0628 \u0645\u0646 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 52\u060c \u0645\u062b\u0644 \u062d\u0630\u0641 \u0627\u0644\u0625\u0643\u0633\u0648\u0646\u0627\u062a \u0645\u0646 45 \u0625\u0644\u0649 52\u060c \u0641\u0647\u0646\u0627\u0643 \u0627\u062d\u062a\u0645\u0627\u0644 \u0623\u0646 \u064a\u0633\u062a\u0641\u064a\u062f \u0645\u0646 \u0639\u0644\u0627\u062c \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\ud83d\udd0d \u0627\u0644\u0646\u0642\u0627\u0637 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u064a\u0633\u0627\u0639\u062f \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0639\u0644\u0649 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0625\u0637\u0627\u0631 \u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0641\u064a \u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062d\u0630\u0641 \u0627\u0644\u0645\u062d\u062f\u062f\u0629.<\/li>\n\n\n\n<li>\u062d\u0648\u0627\u0644\u064a %8 \u0645\u0646 \u0645\u0631\u0636\u0649 \u062f\u0648\u0634\u064a\u0646 \u0645\u0624\u0647\u0644\u0648\u0646.<\/li>\n\n\n\n<li>\u064a\u0639\u062f \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0636\u0631\u0648\u0631\u064a\u064b\u0627 \u0644\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0623\u0647\u0644\u064a\u0629.<\/li>\n\n\n\n<li>\u062a\u0645\u062a \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0645\u062b\u0644 Golodirsen (Vyondys 53) \u0628\u0648\u0627\u0633\u0637\u0629 FDA \u0644\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u062a\u0623\u062b\u0631 \u0628\u0627\u0644\u0625\u0643\u0633\u0648\u0646 53.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"conclusion\"><strong>\u062e\u0627\u062a\u0645\u0629<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u062a\u064f\u0645\u062b\u0644 \u0639\u0644\u0627\u062c\u0627\u062a \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53 \u0622\u0641\u0627\u0642\u064b\u0627 \u0648\u0627\u0639\u062f\u0629 \u0641\u064a \u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a\u060c \u0648\u062e\u0627\u0635\u0629\u064b \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u062d\u0627\u0644\u0627\u062a \u062d\u0630\u0641 \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53. \u0648\u0642\u062f \u0623\u0638\u0647\u0631 \u062f\u0648\u0627\u0621 \u062c\u0648\u0644\u0648\u062f\u064a\u0631\u0633\u0646\u060c \u0648\u0647\u0648 \u0623\u0648\u0644 \u062f\u0648\u0627\u0621 \u0645\u0639\u062a\u0645\u062f \u0645\u0646 FDA \u064a\u0633\u062a\u0647\u062f\u0641 \u0627\u0644\u0625\u0643\u0633\u0648\u0646 53\u060c \u0646\u062a\u0627\u0626\u062c \u0648\u0627\u0639\u062f\u0629 \u0641\u064a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u064f\u0639\u0637\u064a \u0623\u0645\u0644\u064b\u0627 \u0641\u064a \u0625\u0628\u0637\u0627\u0621 \u062a\u0637\u0648\u0631 \u0627\u0644\u0645\u0631\u0636 \u0648\u062a\u062d\u0633\u064a\u0646 \u062c\u0648\u062f\u0629 \u0627\u0644\u062d\u064a\u0627\u0629. \u0648\u0645\u0639 \u0627\u0633\u062a\u0645\u0631\u0627\u0631 \u0627\u0644\u0623\u0628\u062d\u0627\u062b\u060c \u0642\u062f \u064a\u064f\u0635\u0628\u062d \u062a\u062e\u0637\u064a \u0627\u0644\u0625\u0643\u0633\u0648\u0646 \u062c\u0632\u0621\u064b\u0627 \u0644\u0627 \u064a\u062a\u062c\u0632\u0623 \u0645\u0646 \u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u0639\u0644\u0627\u062c\u064a\u0629 \u0623\u0648\u0633\u0639 \u0646\u0637\u0627\u0642\u064b\u0627 \u0644\u0636\u0645\u0648\u0631 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0639\u0636\u0644\u064a\u060c \u0645\u0645\u0627 \u064a\u064f\u0648\u0641\u0631 \u0639\u0644\u0627\u062c\u0627\u062a \u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629\u064b \u0648\u0645\u0644\u0627\u0621\u0645\u0629\u064b \u0644\u0644\u0623\u0641\u0631\u0627\u062f \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0647\u0630\u0647 \u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0645\u064f\u062f\u0645\u0631\u0629.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0645\u0639 \u0627\u0644\u062a\u0642\u062f\u0645 \u0627\u0644\u0645\u0633\u062a\u0645\u0631 \u0641\u064a \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0648\u0627\u0644\u0637\u0628 \u0627\u0644\u0634\u062e\u0635\u064a\u060c \u064a\u0628\u062f\u0648 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 \u0623\u0643\u062b\u0631 \u0625\u0634\u0631\u0627\u0642\u0627 \u0644\u0623\u0648\u0644\u0626\u0643 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u064a\u0634\u0648\u0646 \u0645\u0639 \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u062f\u0648\u0634\u064a\u0646.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0627\u0642\u0631\u0623 \u0627\u0644\u0645\u0632\u064a\u062f<\/strong>:\u00a0<a href=\"https:\/\/dmdwarrior.com\/ar\/dmd-therapies\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646 (\u0642\u0627\u0626\u0645\u0629 \u0628\u062c\u0645\u064a\u0639 \u0627\u0644\u0623\u0628\u062d\u0627\u062b)<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Duchenne Muscular Dystrophy (DMD) is a debilitating and progressive genetic disorder that primarily affects boys, causing muscle weakness and degeneration due to mutations in the dystrophin gene. Over the years, therapeutic advancements have been made to halt the progression of DMD, with one of the most promising being exon skipping therapies. These therapies aim to [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4570,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[155,154,328,77,178],"class_list":["post-4559","post","type-post","status-publish","format-standard","has-post-thumbnail","category-dmd","tag-exon-53","tag-exon-53-skipping","tag-exon-53-skipping-therapy","tag-exon-skipping","tag-exon-skipping-therapies"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/4559","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/comments?post=4559"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/4559\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media\/4570"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media?parent=4559"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/categories?post=4559"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/tags?post=4559"}],"curies":[{"name":"\u0648\u0648\u0631\u062f\u0628\u0631\u064a\u0633","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}