{"id":4350,"date":"2025-08-19T14:31:34","date_gmt":"2025-08-19T11:31:34","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=4350"},"modified":"2025-08-19T15:44:33","modified_gmt":"2025-08-19T12:44:33","slug":"itf-therapeutics-launching-a-study-to-evaluate-the-real-world-experience-of-duvyzat-givinostat-in-patients-with-duchenne-muscular-dystrophy","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ar\/itf-therapeutics-launching-a-study-to-evaluate-the-real-world-experience-of-duvyzat-givinostat-in-patients-with-duchenne-muscular-dystrophy\/","title":{"rendered":"\u0634\u0631\u0643\u0629 ITF Therapeutics \u062a\u064f\u0637\u0644\u0642 \u062f\u0631\u0627\u0633\u0629 \u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0644\u0640 Duvyzat (Givinostat) \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u062f\u0648\u0634\u064a\u0646"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u062a\u0647\u062f\u0641 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0631\u0635\u062f\u064a\u0629 \u0627\u0644\u0627\u0633\u062a\u0634\u0631\u0627\u0641\u064a\u0629 (NCT07127978) \u0625\u0644\u0649 \u062a\u0642\u064a\u064a\u0645 \u0633\u0644\u0627\u0645\u0629 \u0648\u062a\u062d\u0645\u0644 \u0627\u0644\u0645\u0631\u0636\u0649 \u0648\u0646\u062a\u0627\u0626\u062c\u0647\u0645 \u0627\u0644\u0648\u0638\u064a\u0641\u064a\u0629 \u0644\u062f\u0649 \u0645\u0631\u0636\u0649 \u062f\u0648\u0634\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u064a\u0628\u062f\u0623\u0648\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0641\u0645\u0648\u064a \u0628\u0640 Duvyzat (Givinostat) \u0644\u0623\u0648\u0644 \u0645\u0631\u0629\u060c \u0623\u0648 \u0627\u0644\u0630\u064a\u0646 \u0628\u062f\u0623\u0648\u0627 \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u0641\u0639\u0644 \u062e\u0644\u0627\u0644 \u0633\u062a\u0629 \u0623\u0634\u0647\u0631 \u0643\u062c\u0632\u0621 \u0645\u0646 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0642\u064a\u0627\u0633\u064a\u0629 \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629. \u0645\u0639 \u0641\u062a\u0631\u0629 \u062a\u0633\u062c\u064a\u0644 \u0645\u062f\u062a\u0647\u0627 24 \u0634\u0647\u0631\u064b\u0627 \u0648\u0645\u062a\u0627\u0628\u0639\u0629 \u0644\u0627 \u062a\u0642\u0644 \u0639\u0646 \u0639\u0627\u0645\u064a\u0646\u060c \u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u0633\u062a\u0645\u0631 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0644\u0645\u062f\u0629 \u062a\u0635\u0644 \u0625\u0644\u0649 \u062e\u0645\u0633 \u0633\u0646\u0648\u0627\u062a \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u062a\u0645 \u0627\u062e\u062a\u064a\u0627\u0631\u0647\u0645 \u0641\u064a \u0627\u0644\u0628\u062f\u0627\u064a\u0629.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u064a\u062a\u0639\u0644\u0645 \u0623\u0643\u062b\u0631<\/strong>: <a href=\"https:\/\/dmdwarrior.com\/ar\/duvyzat-givinostat-nonsteroidal-drug\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u0645\u0627 \u0647\u0648 \u062f\u0648\u0641\u064a\u0632\u0627\u062a (\u062c\u064a\u0641\u064a\u0646\u0648\u0633\u062a\u0627\u062a)\u061f<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0633\u062a\u0634\u0645\u0644 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 300 \u0645\u0634\u0627\u0631\u0643 (180 \u0645\u0631\u064a\u0636\u064b\u0627 \u063a\u064a\u0631 \u0642\u0627\u062f\u0631 \u0639\u0644\u0649 \u0627\u0644\u0645\u0634\u064a\u060c \u0648\u0645\u0627 \u064a\u0635\u0644 \u0625\u0644\u0649 120 \u0645\u0631\u064a\u0636\u064b\u0627 \u0642\u0627\u062f\u0631\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u0645\u0634\u064a). \u0633\u062a\u062a\u0645 \u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0644\u0645\u062f\u0629 \u0639\u0627\u0645\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0623\u0642\u0644\u060c \u0645\u0639 \u062c\u0645\u0639 \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u062e\u0644\u0627\u0644 \u0627\u0644\u0632\u064a\u0627\u0631\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0631\u0648\u062a\u064a\u0646\u064a\u0629. \u062a\u0634\u0645\u0644 \u0627\u0644\u062a\u0642\u064a\u064a\u0645\u0627\u062a \u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0645\u062e\u062a\u0628\u0631 (\u0645\u062b\u0644 \u0639\u062f\u062f \u0627\u0644\u0635\u0641\u0627\u0626\u062d \u0627\u0644\u062f\u0645\u0648\u064a\u0629\u060c \u0648\u0627\u0644\u062f\u0647\u0648\u0646 \u0627\u0644\u062b\u0644\u0627\u062b\u064a\u0629)\u060c \u0648\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0631\u0626\u0629\u060c \u0648\u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062a\u064a \u064a\u064f\u0628\u0644\u063a \u0639\u0646\u0647\u0627 \u0627\u0644\u0645\u0631\u0636\u0649\u060c \u0648\u0645\u0642\u0627\u064a\u064a\u0633 \u0627\u0644\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u062d\u0631\u0643\u064a\u0629 \u0645\u062b\u0644 \u062a\u0642\u064a\u064a\u0645 \u0646\u0648\u0631\u062b \u0633\u062a\u0627\u0631 \u0644\u0644\u0645\u0634\u064a (NSAA) \u0648\u0645\u0642\u064a\u0627\u0633 \u0623\u062f\u0627\u0621 \u0627\u0644\u0637\u0631\u0641 \u0627\u0644\u0639\u0644\u0648\u064a (PUL).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u062f\u0631\u0627\u0633\u0629 Duvyzat (Givinostat) - NCT07127978 -<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u062a\u0647\u062f\u0641 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0625\u0644\u0649 \u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u062e\u0628\u0631\u0629 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0644\u062f\u0648\u0627\u0621 \u062c\u064a\u0641\u064a\u0646\u0648\u0633\u062a\u0627\u062a \u0641\u064a \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u062f\u0648\u0634\u064a\u0646. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0628\u062f\u0621 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 (\u0645\u0642\u062f\u0631)<\/strong>: 2025-09-15<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0627\u0644\u0625\u0643\u0645\u0627\u0644 \u0627\u0644\u0623\u0633\u0627\u0633\u064a (\u062a\u0642\u062f\u064a\u0631\u064a):<\/strong> 2030-06-30<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0625\u0643\u0645\u0627\u0644 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 (\u062a\u0642\u062f\u064a\u0631\u064a)<\/strong>: 2030-07-30<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0639\u062f\u062f \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 (\u062a\u0642\u062f\u064a\u0631\u064a)<\/strong>: 300<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0646\u0648\u0639 \u0627\u0644\u062f\u0631\u0627\u0633\u0629<\/strong>: \u0631\u0635\u062f\u064a<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0627\u0644\u0645\u0648\u0627\u0642\u0639<\/strong>:\u0644\u0627 \u062a\u0648\u062c\u062f \u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0645\u0648\u0642\u0639 \u062d\u062a\u0649 \u0627\u0644\u0622\u0646.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u0627\u0644\u0623\u0639\u0645\u0627\u0631 \u0627\u0644\u0645\u0624\u0647\u0644\u0629 \u0644\u0644\u062f\u0631\u0627\u0633\u0629<\/strong>:6 \u0633\u0646\u0648\u0627\u062a \u0648\u0645\u0627 \u0641\u0648\u0642 (\u0637\u0641\u0644\u060c \u0628\u0627\u0644\u063a\u060c \u0634\u062e\u0635 \u0628\u0627\u0644\u063a \u0643\u0628\u064a\u0631 \u0627\u0644\u0633\u0646)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0625\u062f\u0631\u0627\u062c \u0648\u0627\u0644\u0627\u0633\u062a\u0628\u0639\u0627\u062f \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629. <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT07127978\" target=\"_blank\" rel=\"noreferrer noopener\">NCT07127978<\/a> -<\/p>","protected":false},"excerpt":{"rendered":"<p>The purpose of this prospective observational study (NCT07127978) is to assess the safety, tolerability, and functional results of DMD patients who are starting oral Duvyzat (Givinostat) for the first time or who have already begun therapy within six months as part of standard clinical care in the United States. With a 24-month enrollment period and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4353,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[46,47],"class_list":["post-4350","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-duvyzat","tag-givinostat"],"_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/4350","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/comments?post=4350"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/4350\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media\/4353"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media?parent=4350"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/categories?post=4350"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/tags?post=4350"}],"curies":[{"name":"\u0648\u0648\u0631\u062f\u0628\u0631\u064a\u0633","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}