{"id":2162,"date":"2025-01-01T12:34:10","date_gmt":"2025-01-01T09:34:10","guid":{"rendered":"https:\/\/dmdwarrior.com\/?p=2162"},"modified":"2025-01-01T12:34:11","modified_gmt":"2025-01-01T09:34:11","slug":"new-research-c-terminal-ct-domain-between-dystrophin-and-dystrobrevin","status":"publish","type":"post","link":"https:\/\/dmdwarrior.com\/ar\/new-research-c-terminal-ct-domain-between-dystrophin-and-dystrobrevin\/","title":{"rendered":"\u0623\u0628\u062d\u0627\u062b \u062c\u062f\u064a\u062f\u0629 \u062d\u0648\u0644 \u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0645\u0631\u0636 \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u062f\u0648\u0634\u064a\u0646 \u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u0639\u0644\u0627\u062c\u0627\u062a \u0623\u0643\u062b\u0631 \u0627\u0633\u062a\u0647\u062f\u0627\u0641\u064b\u0627"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u0623\u0638\u0647\u0631 \u0627\u0643\u062a\u0634\u0627\u0641 \u0631\u0627\u0626\u062f \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0627\u0644\u0645\u0639\u0642\u062f\u0629 \u0628\u064a\u0646 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646\u060c \u0648\u0647\u0648 \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a\u060c \u0648\u0628\u0631\u0648\u062a\u064a\u0646\u0647 \u0627\u0644\u0645\u0631\u0627\u0641\u0642\u060c \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0628\u0631\u064a\u0641\u064a\u0646\u060c \u0645\u0645\u0627 \u064a\u0641\u062a\u062d \u0622\u0641\u0627\u0642\u064b\u0627 \u062c\u062f\u064a\u062f\u0629 \u0644\u062f\u0631\u0627\u0633\u0629 \u0648\u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u062f\u0648\u0634\u064a\u0646.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u064a\u0635\u0641 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u0637\u0631\u0641 \u0627\u0644\u0637\u0631\u0641\u064a C (CT) \u0627\u0644\u0645\u0634\u0641\u0631\u0629 \u0644\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0648\u062f\u0648\u0631\u0647\u0627 \u0641\u064a \u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0627\u0644\u0623\u063a\u0634\u064a\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0639\u0628\u0631 \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0641\u064a \u0645\u062c\u0644\u0629 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0641\u064a \u0634\u0647\u0631 \u062f\u064a\u0633\u0645\u0628\u0631.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u0642\u0627\u0644 \u0643\u0631\u064a\u0634\u0646\u0627 \u0645\u0627\u0644\u064a\u0644\u0627\u060c \u0623\u0633\u062a\u0627\u0630 \u0643\u0644\u064a\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0629 \u0648\u0627\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0635\u064a\u062f\u0644\u0627\u0646\u064a\u0629 \u0628\u062c\u0627\u0645\u0639\u0629 \u0643\u0648\u0644\u0648\u0631\u0627\u062f\u0648 \u0633\u0643\u0627\u062c\u0632\u060c \u0648\u0627\u0644\u0645\u0624\u0644\u0641 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0644\u0644\u062f\u0631\u0627\u0633\u0629: &quot;\u064a\u0633\u0644\u0637 \u0647\u0630\u0627 \u0627\u0644\u0628\u062d\u062b \u0627\u0644\u0636\u0648\u0621 \u0639\u0644\u0649 \u0627\u0644\u062f\u064a\u0646\u0627\u0645\u064a\u0643\u064a\u0627\u062a \u0627\u0644\u0645\u0639\u0642\u062f\u0629 \u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0648\u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0628\u0631\u064a\u0641\u064a\u0646\u060c \u0645\u0645\u0627 \u064a\u0648\u0641\u0631 \u0631\u0624\u0649 \u062d\u0627\u0633\u0645\u0629 \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0641\u064a\u062f \u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0639\u0644\u0627\u062c \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644&quot;. \u0625\u0646 \u0641\u0647\u0645\u0646\u0627 \u0644\u0643\u064a\u0641\u064a\u0629 \u0639\u0645\u0644 \u0647\u0630\u0647 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0641\u064a \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0645\u062a\u0646\u0648\u0639\u0629 \u0647\u0648 \u062e\u0637\u0648\u0629 \u0623\u0642\u0631\u0628 \u0625\u0644\u0649 \u0625\u064a\u062c\u0627\u062f \u0639\u0644\u0627\u062c\u0627\u062a \u0644\u0645\u0631\u0636 \u062f\u0648\u0634\u064a\u0646 \u062a\u0633\u062a\u0647\u062f\u0641 \u0627\u0644\u0623\u0633\u0628\u0627\u0628 \u0627\u0644\u062c\u0630\u0631\u064a\u0629.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/news.cuanschutz.edu\/news-stories\/new-study-uncovers-key-insights-into-protein-interactions-in-duchenne-muscular-dystrophy-paving-way-for-more-targeted-therapies\" target=\"_blank\" rel=\"noreferrer noopener\">\u0627\u0642\u0631\u0623 \u0627\u0644\u0645\u0632\u064a\u062f<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(24)02504-3\/fulltext\" target=\"_blank\" rel=\"noreferrer noopener\">\u0631\u0627\u0628\u0637 \u0627\u0644\u0628\u062d\u062b<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>A pioneering discovery has shown the complicated relationships between dystrophin, a muscle stability protein, and its companion protein, dystrobrevin, opening new avenues for studying and treating Duchenne Muscular Dystrophy. Researchers describe dystrophin cryptic C-terminal (CT) region and its role in maintaining cellular membranes across tissues in the December Journal of Biological Chemistry. \u201cThis research highlights [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2166,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[66,74,73,61],"class_list":["post-2162","post","type-post","status-publish","format-standard","has-post-thumbnail","category-research","tag-duchenne-muscular-dystrophy","tag-dystrobrevin","tag-dystrophin","tag-gene-therapy"],"subtitle":"\u062a\u0634\u0631\u062d \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0643\u064a\u0641\u064a\u0629 \u0639\u0645\u0644 \u0627\u0644\u062f\u064a\u0633\u062a\u0631\u0648\u0641\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u060c \u0648\u062a\u0643\u0634\u0641 \u0643\u064a\u0641 \u064a\u0645\u0643\u0646 \u062a\u0637\u0648\u064a\u0631 \u0623\u062f\u0648\u064a\u0629 \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a.","_links":{"self":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/2162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/comments?post=2162"}],"version-history":[{"count":0,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/posts\/2162\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media\/2166"}],"wp:attachment":[{"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/media?parent=2162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/categories?post=2162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dmdwarrior.com\/ar\/wp-json\/wp\/v2\/tags?post=2162"}],"curies":[{"name":"\u0648\u0648\u0631\u062f\u0628\u0631\u064a\u0633","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}